1991
Molecular biology of renal Na(+)-H+ exchangers.
Igarashi P, Reilly RF, Hildebrandt F, Biemesderfer D, Rebouças NA, Slayman CW, Aronson PS. Molecular biology of renal Na(+)-H+ exchangers. Kidney International Supplement 1991, 33: s84-9. PMID: 1653876.Commentaries, Editorials and LettersConceptsKb cDNALLC-PK1 cellsSteady-state transcript levelsPlasma membrane proteinsMembrane-associated domainSequence of cDNACDNA library screeningAmino acid sequenceExchanger gene expressionNorthern blot analysisEvolutionary conservationRenal epithelial cellsCytoplasmic domainMembrane proteinsRegulation of intracellularAcid sequenceTranscript levelsUntranslated regionGene expressionSimilar transcriptsCDNALibrary screeningMolecular biologyPolymerase chain reactionBlot analysis
1985
The plasma membrane sodium-hydrogen exchanger and its role in physiological and pathophysiological processes.
Mahnensmith RL, Aronson PS. The plasma membrane sodium-hydrogen exchanger and its role in physiological and pathophysiological processes. Circulation Research 1985, 56: 773-788. PMID: 2988813, DOI: 10.1161/01.res.56.6.773.Commentaries, Editorials and LettersMeSH KeywordsAcid-Base EquilibriumAnimalsBiological Transport, ActiveBlood PlateletsCalciumCarrier ProteinsCations, MonovalentCell MembraneEpitheliumHormonesHumansHydrogenHydrogen-Ion ConcentrationHypertensionLeukocytesMembrane ProteinsNeoplasmsSodiumSodium-Hydrogen ExchangersSodium-Potassium-Exchanging ATPaseWater-Electrolyte BalanceConceptsSodium-hydrogen exchangerCellular acid-base homeostasisAllosteric regulationPlasma membraneRegulation of intracellularStimulus-response couplingIntracellular protonsPathophysiological processesPhysiological roleTransport systemTransmembrane exchangeCell growthAcid-base homeostasisRegulationSodium-hydrogen exchangeKinetic propertiesSuch diverse conditionsMetabolic responsePathophysiological roleDiverse conditionsCellsCell volumeRoleHomeostasisIntracellular
1982
Modifier role of internal H+ in activating the Na+–H+ exchanger in renal microvillus membrane vesicles
Aronson P, Nee J, Suhm M. Modifier role of internal H+ in activating the Na+–H+ exchanger in renal microvillus membrane vesicles. Nature 1982, 299: 161-163. PMID: 7110335, DOI: 10.1038/299161a0.Peer-Reviewed Original Research