2011
The RNA Interference Pathway in Trypanosoma brucei
Ullu E, Kolev N, Barnes R, Tschudi C. The RNA Interference Pathway in Trypanosoma brucei. Nucleic Acids And Molecular Biology 2011, 28: 167-185. DOI: 10.1007/978-3-642-28687-2_8.Peer-Reviewed Original ResearchRNA interference (RNAi) pathwayInterference pathwayEarly divergent eukaryoteMost eukaryotic cellsSequence-specific mannerEukaryotic evolutionDivergent eukaryotesHigher eukaryotesRNAi machineryEukaryotic cellsLong dsRNAsRNAi mechanismTarget transcriptsTrypanosoma bruceiConsequence cellsSpecific defense mechanismsEukaryotesProtozoan parasiteDefense mechanismsTranscriptsCurrent understandingNucleic acidsPathwayHighlight similaritiesSuch mechanisms
2000
A new twist in trypanosome RNA metabolism: cis-splicing of pre-mRNA.
Mair G, Shi H, Li H, Djikeng A, Aviles H, Bishop J, Falcone F, Gavrilescu C, Montgomery J, Santori M, Stern L, Wang Z, Ullu E, Tschudi C. A new twist in trypanosome RNA metabolism: cis-splicing of pre-mRNA. RNA 2000, 6: 163-9. PMID: 10688355, PMCID: PMC1369902, DOI: 10.1017/s135583820099229x.Peer-Reviewed Original ResearchConceptsCis-spliced intronsSplice siteGT/AG ruleSmall intergenic regionAncient acquisitionGene arrangementTrypanosome genomeEukaryotic cellsRNA metabolismIntergenic regionIntron removalLeader sequenceTrypanosoma bruceiIntronsNucleotide positionsAG dinucleotideEuglena gracilisTrypanosoma cruziPolymerase geneIdentical positionsPoint mutationsRecent discoveryPAP mRNAGenesMRNA