2024
Nonadjuvanted Bivalent Respiratory Syncytial Virus Vaccination and Perinatal Outcomes
Son M, Riley L, Staniczenko A, Cron J, Yen S, Thomas C, Sholle E, Osborne L, Lipkind H. Nonadjuvanted Bivalent Respiratory Syncytial Virus Vaccination and Perinatal Outcomes. JAMA Network Open 2024, 7: e2419268. PMID: 38976271, PMCID: PMC11231799, DOI: 10.1001/jamanetworkopen.2024.19268.Peer-Reviewed Original ResearchConceptsRespiratory syncytial virusNeonatal intensive care unitPreterm birthWeeks gestationRisk of HDPPerinatal outcomesLogistic regression modelsIncreased riskPregnant individualsPrenatal vaccinationSmall-for-gestational age birth weightNeonatal intensive care unit admissionCohort studyIncreased risk of PTBOdds ratioIncreased risk of HDPRisk of preterm birthRespiratory syncytial virus seasonRespiratory syncytial virus vaccineRetrospective observational cohort studyNeonatal respiratory distressVaccination statusMultivariate logistic regression modelObservational cohort studyCox regression modelsCo-existing chronic hypertension and hypertensive disorders of pregnancy and associated adverse pregnancy outcomes
Sweeney L, Lundsberg L, Culhane J, Partridge C, Son M. Co-existing chronic hypertension and hypertensive disorders of pregnancy and associated adverse pregnancy outcomes. The Journal Of Maternal-Fetal & Neonatal Medicine 2024, 37: 2305675. PMID: 38290827, DOI: 10.1080/14767058.2024.2305675.Peer-Reviewed Original ResearchConceptsHypertensive disorders of pregnancyDisorders of pregnancyNeonatal outcomesChronic hypertensionHypertensive disordersIntensive care unitCesarean deliveryOdds of cesarean deliveryPregnant personsBlood pressureBivariate tests of associationHypertensive conditionsMaternal ICU admissionPreterm birth <Intensive care unit admissionAntihypertensive medication useBaseline clinical dataElectronic medical recordsTests of associationRetrospective cohort studySGA birthweightEligible peopleGestational ageMaternal comorbiditiesSingleton deliveries
2023
Using a Patient Educational Video to Improve Knowledge of Maternal Mortality Warning Signs
White K, Tortal D, Callahan K, Eng K, Hyland M, Underwood E, Senter L, León-Martínez D, Son M, Lipkind H. Using a Patient Educational Video to Improve Knowledge of Maternal Mortality Warning Signs. Obstetrics And Gynecology 2023, 142: 1139-1147. PMID: 37708502, DOI: 10.1097/aog.0000000000005368.Peer-Reviewed Original ResearchConceptsPercentage of participantsPosteducation questionnairesPrimary outcomePatient knowledgeDischarge educationSignificant differencesBaseline knowledge questionnairePatient educational videoRoutine discharge educationTertiary care hospitalVideo educationQuestionnaire total scorePercent of participantsWarning signsPostpartum maternal mortalityBaseline characteristicsCare hospitalPostpartum educationEligible participantsMaternal mortalityPostpartum individualsRoutine educationKnowledge questionnaireCommercial insuranceAbsolute increaseSevere maternal morbidity rates in a US-based electronic health record database, 2018–2022
Son M, Culhane J, Louis J, Handley S, Burris H, Greenspan J, McKenney K, Dysart K. Severe maternal morbidity rates in a US-based electronic health record database, 2018–2022. Journal Of Perinatology 2023, 43: 1316-1318. PMID: 37640810, DOI: 10.1038/s41372-023-01765-7.Peer-Reviewed Original ResearchThe association between a low 50-gram, 1-hour glucose challenge test value and neonatal morbidity
Ding J, Lundsberg L, Culhane J, Patridge C, Milley L, Son M. The association between a low 50-gram, 1-hour glucose challenge test value and neonatal morbidity. The Journal Of Maternal-Fetal & Neonatal Medicine 2023, 36: 2245527. PMID: 37558273, DOI: 10.1080/14767058.2023.2245527.Peer-Reviewed Original ResearchConceptsGlucose challenge test valuesTertiary care academic hospitalDiagnosis of GDMGlycemic screeningGCT valuesNICU admissionNeonatal outcomesMorbidity outcomesAcademic hospitalNeonatal intensive care unit admissionSingle tertiary care academic hospitalIntensive care unit admissionMultivariable logistic regression modelingComposite morbidity outcomeNeonatal morbidity outcomesCare unit admissionRetrospective cohort studyNewborns of mothersRisk of morbidityLogistic regression modelingEligible patientsUnit admissionAntenatal surveillanceGestational diabetesHypertensive disordersFetal growth restriction and small for gestational age as predictors of neonatal morbidity: which growth nomogram to use?
Leon-Martinez D, Lundsberg L, Culhane J, Zhang J, Son M, Reddy U. Fetal growth restriction and small for gestational age as predictors of neonatal morbidity: which growth nomogram to use? American Journal Of Obstetrics And Gynecology 2023, 229: 678.e1-678.e16. PMID: 37348779, DOI: 10.1016/j.ajog.2023.06.035.Peer-Reviewed Original ResearchConceptsNeonatal composite outcomeComposite outcomeFetal growth restrictionGestational ageFetal weightWeeks of gestationPositive likelihood ratioGrowth restrictionNonanomalous singleton pregnanciesPoor neonatal outcomeRetrospective cohort studySingle academic centerWeeks of deliveryDays of deliveryFetal growth referencesElectronic medical recordsProportion of fetusesLikelihood ratioNeonatal morbidityNeonatal outcomesPerinatal outcomesCohort studySingleton pregnanciesNeonatal dataMedical recordsLow-Dose Aspirin during Pregnancy and Postpartum Bleeding
White K, Son M, Lundsberg L, Culhane J, Partridge C, Reddy U, Merriam A. Low-Dose Aspirin during Pregnancy and Postpartum Bleeding. American Journal Of Perinatology 2023, 40: 1390-1397. PMID: 37211010, DOI: 10.1055/a-2096-5199.Peer-Reviewed Original ResearchConceptsLow-dose aspirinPostpartum blood lossTiming of discontinuationBlood lossPostpartum bleedingPostpartum hemorrhageLDA useUse of LDARed blood cell transfusionBlood cell transfusionRetrospective cohort studySystemic lupus erythematosusTime of deliveryDiagnosis of diabetesLogistic regression modelingElectronic medical recordsAspirin 81Ideal dosingPreeclampsia preventionCell transfusionDose aspirinCohort studyHypertensive diseaseLupus erythematosusPrimary outcomeAntibiotic choice for Group B Streptococcus prophylaxis in mothers with reported penicillin allergy and associated newborn outcomes
Snider J, Mithal L, Kwah J, Rhodes N, Son M. Antibiotic choice for Group B Streptococcus prophylaxis in mothers with reported penicillin allergy and associated newborn outcomes. BMC Pregnancy And Childbirth 2023, 23: 400. PMID: 37254067, PMCID: PMC10228028, DOI: 10.1186/s12884-023-05697-0.Peer-Reviewed Original ResearchConceptsGroup B streptococcus prophylaxisReported penicillin allergyPenicillin allergyGBS prophylaxisLab drawsNeonatal outcomesNewborn outcomesAntibiotic administrationMedical recordsPregnant individualsIntrapartum group B streptococcus prophylaxisNeonatal intensive care unit admissionDesignThis retrospective cohort studyIntensive care unit admissionSelf-reported penicillin allergyNeonates of mothersCare unit admissionIntrapartum antibiotic prophylaxisRetrospective cohort studyWeeks of gestationMother-infant pairsMother-infant dyadsBeta-lactam antibioticsAntibiotic prophylaxisUnit admissionIntravenous iron for treatment of iron deficiency anemia during pregnancy and associated maternal outcomes
Burn M, Lundsberg L, Culhane J, Partridge C, Son M. Intravenous iron for treatment of iron deficiency anemia during pregnancy and associated maternal outcomes. The Journal Of Maternal-Fetal & Neonatal Medicine 2023, 36: 2192855. PMID: 36958808, DOI: 10.1080/14767058.2023.2192855.Peer-Reviewed Original ResearchConceptsIron deficiency anemiaMaternal morbidity compositeIntravenous ironMorbidity compositePotential confoundersElectronic medical recordsPregnant patientsTreatment courseDeficiency anemiaHigh-risk baseline characteristicsMultivariable logistic regression modellingRetrospective cohort studyFull treatment courseHospital electronic medical recordsIntensive care unitLogistic regression modellingGreater increaseMaternal morbidityMaternal outcomesNeonatal outcomesBaseline characteristicsCohort studyBlood transfusionPrimary outcomeTerm deliveryManagement of the Pregnant Trauma Patient: A Systematic Literature Review
Liggett M, Amro A, Son M, Schwulst S. Management of the Pregnant Trauma Patient: A Systematic Literature Review. Journal Of Surgical Research 2023, 285: 187-196. PMID: 36689816, DOI: 10.1016/j.jss.2022.11.075.Peer-Reviewed Original ResearchConceptsPregnant trauma patientsPerimortem cesarean sectionMaternal cardiac arrestTrauma patientsCesarean sectionCardiac arrestNon-obstetric maternal deathAdditional high-quality studiesTrauma CT scansKleihauer-Betke testingEvidence-based recommendationsHigh-quality studiesPregnant patientsMaternal deathsTranexamic acidPrognostic valueCochrane LibraryFetal mortalityKB testTraumatic injuryCT scanGeneral surgeonsPrognostic potentialRadiographic studiesReference listsMaximum Dose Rate of Intrapartum Oxytocin Infusion and Associated Obstetric and Perinatal Outcomes
Son M, Roy A, Grobman W, Miller E, Dude A, Peaceman A, Stetson B. Maximum Dose Rate of Intrapartum Oxytocin Infusion and Associated Obstetric and Perinatal Outcomes. Obstetrics And Gynecology 2023, 141: 379-386. PMID: 36649339, DOI: 10.1097/aog.0000000000005058.Peer-Reviewed Original ResearchConceptsTitration regimenCesarean deliveryVaginal deliveryMultivariable analysisAdverse outcomesNeonatal intensive care unit admissionComposite severe neonatal morbidityIntensive care unit admissionSecondary analysisCumulative proportionPerinatal adverse outcomesCare unit admissionSevere neonatal morbiditySpontaneous vaginal deliveryMagnesium sulfate infusionUnderwent cesarean deliveryRupture of membranesWeeks of gestationNICU admissionUnit admissionHypertensive disordersLack of evidenceNeonatal morbidityNulliparous patientsPerinatal outcomes
2022
What Is Long-Acting Reversible Contraception?
Stark EL, Gariepy AM, Son M. What Is Long-Acting Reversible Contraception? JAMA 2022, 328: 1362-1362. PMID: 35960529, DOI: 10.1001/jama.2022.14239.Peer-Reviewed Educational MaterialsSurvey of Obstetric Providers to Assess the Knowledge and Management of a Reported Penicillin Allergy in Pregnant Women
Cate JJM, Burn M, Kwah J, Liao J, Illuzzi J, Reddy U, Son M. Survey of Obstetric Providers to Assess the Knowledge and Management of a Reported Penicillin Allergy in Pregnant Women. American Journal Of Perinatology 2022, 40: 001-008. PMID: 35709740, DOI: 10.1055/a-1877-9970.Peer-Reviewed Original ResearchConceptsPenicillin skin testingReported penicillin allergyPenicillin allergyObstetric providersPractice patternsEducational sessionsAllergy knowledgeProvider knowledgeEducational interventionSingle academic medical centerPenicillin allergy delabelingPenicillin allergy evaluationPenicillin allergy testingPercentage of patientsIdentification of patientsClinical practice patternsSmall group educational sessionsAcademic medical centerChi-square testAllergy evaluationPenicillin allergicPerinatal outcomesPregnant patientsDrug allergyAllergy testingThe Uptake of Telemedicine in Obstetric Care During the Early Acute Phase of the Coronavirus 2019 Pandemic
McKenney KM, Lundsberg LS, Burris HH, Ledyard RF, Son M, Greenspan J, Handley SC, Dysart K, Culhane J. The Uptake of Telemedicine in Obstetric Care During the Early Acute Phase of the Coronavirus 2019 Pandemic. Telemedicine Journal And E-Health 2022, 29: 617-620. PMID: 36067146, DOI: 10.1089/tmj.2022.0291.Peer-Reviewed Original ResearchConceptsEarly acute phasePrenatal careTelemedicine useAcute phaseObstetric careElectronic medical record dataPrenatal care provisionCoronavirus disease 2019 (COVID-19) pandemicMedical record dataDisease 2019 pandemicCoronavirus 2019 (COVID-19) pandemicUptake of telemedicineHealth care deliveryObstetric telemedicineTotal visitsCare deliveryEarly pandemicCare provisionRecord dataCareDelivery modeSignificant differencesTelemedicine usersTelemedicineEarly timingChanges in preterm birth during the COVID-19 pandemic by duration of exposure and race and ethnicity
Mullin AM, Handley SC, Lundsberg L, Elovitz MA, Lorch SA, McComb EJ, Montoya-Williams D, Yang N, Dysart K, Son M, Greenspan J, Culhane JF, Burris HH. Changes in preterm birth during the COVID-19 pandemic by duration of exposure and race and ethnicity. Journal Of Perinatology 2022, 42: 1346-1352. PMID: 35974082, PMCID: PMC9379882, DOI: 10.1038/s41372-022-01488-1.Peer-Reviewed Original ResearchConceptsBlack-White disparitiesDuration of exposureOverall PTBPTB phenotypesPreterm birthWhite patientsStudy designWeHigh riskLower riskPandemic exposureNew HavenRacial disparitiesPatientsPrior yearCOVID-19 pandemicWeeksExposure durationExposureBirthRiskPandemicDurationDisparitiesPTBPandemic effectsOutpatient penicillin allergy evaluation during pregnancy and associated clinical outcomes
Kwah JH, Burn MS, Liao J, Cate J, Son M. Outpatient penicillin allergy evaluation during pregnancy and associated clinical outcomes. American Journal Of Obstetrics & Gynecology MFM 2022, 4: 100674. PMID: 35691578, DOI: 10.1016/j.ajogmf.2022.100674.Peer-Reviewed Original ResearchConceptsPenicillin allergy evaluationPenicillin allergyPregnant womenAllergy evaluationHospital stayNeonatal outcomesClinical benefitIntensive care unit admissionBirth hospitalization lengthUnverified penicillin allergyCare unit admissionNeonatal adverse outcomesRetrospective cohort studyMedical record reviewPostpartum hospital stayAdditional clinical benefitLarge academic hospitalElectronic medical recordsBeta-lactam antibioticsPostpartum infectionReferred womenUnit admissionMaternal outcomesCohort studyTrue allergyPostpartum Length of Stay and Hospital Readmission Before and During the Coronavirus Disease 2019 (COVID-19) Pandemic
Handley SC, Gallagher K, Lindgren E, Lo JY, Burris HH, Dysart KC, Greenspan J, Culhane JF, Son M. Postpartum Length of Stay and Hospital Readmission Before and During the Coronavirus Disease 2019 (COVID-19) Pandemic. Obstetrics And Gynecology 2022, 139: 381-390. PMID: 35115443, DOI: 10.1097/aog.0000000000004687.Peer-Reviewed Original ResearchConceptsCoronavirus disease 2019 (COVID-19) pandemicObstetric patientsHospital readmissionMode of deliveryPostpartum hospitalizationDisease 2019 pandemicHospitalization dischargeCOVID-19 pandemicRetrospective cohort studyWeeks of gestationDays of deliveryLogistic mixed-effects modelsCohort studyHospitalization lengthSecondary outcomesPrimary outcomeAdjusted analysisStudy cohortVaginal birthCesarean birthReadmissionPostpartum lengthPatientsHospitalizationMixed-effects modelsIntrapartum nipple stimulation therapy for labor induction: a randomized controlled external pilot study of acceptability and feasibility
Stark EL, Athens ZG, Son M. Intrapartum nipple stimulation therapy for labor induction: a randomized controlled external pilot study of acceptability and feasibility. American Journal Of Obstetrics & Gynecology MFM 2022, 4: 100575. PMID: 35042047, DOI: 10.1016/j.ajogmf.2022.100575.Peer-Reviewed Original ResearchConceptsObstetrical care providersExternal pilot studyLabor inductionStimulation therapyOxytocin infusionNipple stimulationPain levelsCare providersPilot studyInitiation of oxytocinPrimary outcome measureElectric breast pumpWeeks of gestationNeonatal intensive careParticipants' pain levelsNon-English speakingEligible womenMedian durationIntervention startMedian timeIntensive careMinutes of stimulationBreast pumpLabor progressOutcome measures
2021
Birth Hospital Length of Stay and Rehospitalization During COVID-19
Handley SC, Gallagher K, Breden A, Lindgren E, Lo JY, Son M, Murosko D, Dysart K, Lorch SA, Greenspan J, Culhane JF, Burris HH. Birth Hospital Length of Stay and Rehospitalization During COVID-19. Pediatrics 2021, 149: e2021053498. PMID: 34889449, PMCID: PMC9645693, DOI: 10.1542/peds.2021-053498.Peer-Reviewed Original ResearchConceptsInfant rehospitalizationAdjusted odds ratioTerm infantsBirth hospitalization dischargeBirth hospitalization lengthHealthy term infantsRetrospective cohort studyCoronavirus disease 2019 eraDay of birthCOVID-19Hospitalization dischargePrepandemic eraHospital lengthMultivariable adjustmentCohort studyHospitalization lengthShorter LOSAdjusted analysisOdds ratioRehospitalizationInfantsHealth systemAdditional outcomesCOVID-19 eraMixed effects modelsDuration of Exposure to General Endotracheal Anesthesia during Cesarean Deliveries at Term and Perinatal Complications
Swanson K, Liang L, Grobman WA, Higgins N, Roy A, Son M. Duration of Exposure to General Endotracheal Anesthesia during Cesarean Deliveries at Term and Perinatal Complications. American Journal Of Perinatology 2021, 39: 232-237. PMID: 34844279, DOI: 10.1055/s-0041-1739355.Peer-Reviewed Original ResearchConceptsGeneral endotracheal anesthesiaPrimary perinatal outcomeCesarean deliveryPerinatal complicationsPerinatal outcomesDuration of exposureMaternal morbidityMultivariable analysisGeneral anesthesiaEndotracheal anesthesiaFetal statusSingle tertiary care centerComposite of complicationsPrior abdominal surgeryTertiary care centerWeeks of gestationMaternal complicationsNonanomalous gestationsApgar scoreMultivariable adjustmentSecondary outcomesAbdominal surgeryBivariable analysisRetrospective studyCare center