2024
A call to address penicillin allergy labels in patients with hematopoietic stem cell transplants: How to avoid rash decisions
Belmont A, Stone C, Guyer A, Edelman E, Trubiano J. A call to address penicillin allergy labels in patients with hematopoietic stem cell transplants: How to avoid rash decisions. Transplant Infectious Disease 2024, e14350. PMID: 39101669, DOI: 10.1111/tid.14350.Peer-Reviewed Original ResearchHematopoietic stem cell transplantationStem cell transplantationPenicillin allergy labelMultidrug-resistant infectionsPenicillin allergyCell transplantationAllergy labelsAssociated with more severe infectionsReported penicillin allergyRisk-stratify patientsMore severe infectionsPoint-of-care assessmentBeta-lactam antibioticsClinical decision toolTolerate penicillinsAssociated with useDelabel patientsTherapeutic optionsEvaluating patientsSevere infectionsAlternative antibioticsOral challengeClinical care settingsClostridium difficilePatientsASSOCIATIONS BETWEEN REDUCTIONS IN DEPRESSIVE SYMPTOMS AND REDUCTIONS IN PAIN AND ANXIETY SYMPTOMS AND SUBSTANCE USE: EMULATION OF A RANDOMIZED TRIAL
Khan M, Acri M, Ban K, Scheidell J, Stevens E, Manandhar-Sasaki P, Charles D, Chichetto N, Crystal S, Gordan A, Marshall B, Edelman E, Justice A, Braithwaite R, Caniglia E. ASSOCIATIONS BETWEEN REDUCTIONS IN DEPRESSIVE SYMPTOMS AND REDUCTIONS IN PAIN AND ANXIETY SYMPTOMS AND SUBSTANCE USE: EMULATION OF A RANDOMIZED TRIAL. AJPM Focus 2024, 100258. DOI: 10.1016/j.focus.2024.100258.Peer-Reviewed Original ResearchUnhealthy alcohol useDepressive symptomsAnxiety symptomsIllicit opioid useOdds ratioAlcohol useVeterans Aging Cohort StudyPain symptomsConfidence intervalsTarget trial emulation frameworkElevated depressive symptomsAssociated with reductionsReducing depressive symptomsAging Cohort StudySubstance useOpioid useMultisite observational studyDepressive symptom reductionNext follow-up visitUS veteransReduce painFollow-up visitCohort studyAntidepressant medicationComparing individualsW81 Implementation Facilitation Improves Clinician Readiness to Provide Emergency Department-Initiated Buprenorphine in Four Urban Academic Centers
Hawk K, D'Onofrio G, Chawarski M, Coupet E, Cowan E, Curry L, Freiermurth C, Lyons M, Murphy A, O'Connor P, Richardson L, Rothman R, Whiteside L, Williams J, Fiellin D, Edelman E. W81 Implementation Facilitation Improves Clinician Readiness to Provide Emergency Department-Initiated Buprenorphine in Four Urban Academic Centers. Drug And Alcohol Dependence 2024, 260: 110699. DOI: 10.1016/j.drugalcdep.2023.110699.Peer-Reviewed Original ResearchW31 The Impact of Tobacco Use on Liver-Related Morbidity in Patients With Cirrhosis
Haque L, Fiellin D, Bryant K, Edelman E, Justice A, Lim J, Re V, Marshall B, Taddei T, Tate J, Tetrault J, Williams E, McGinnis K. W31 The Impact of Tobacco Use on Liver-Related Morbidity in Patients With Cirrhosis. Drug And Alcohol Dependence 2024, 260: 110649. DOI: 10.1016/j.drugalcdep.2023.110649.Peer-Reviewed Original ResearchM145 Assessing Provider Readiness to Implement Pre-Exposure Prophylaxis for HIV Prevention and Medications for Opioid Use Disorder Among People who Inject Drugs
Pickering E, Sung M, Bailey G, Buchelli M, Davidson D, Jenkins M, John B, Kolakowski J, Maier L, Porter E, Perez O, Rash C, Edelman E, Viera A. M145 Assessing Provider Readiness to Implement Pre-Exposure Prophylaxis for HIV Prevention and Medications for Opioid Use Disorder Among People who Inject Drugs. Drug And Alcohol Dependence 2024, 260: 110425. DOI: 10.1016/j.drugalcdep.2023.110425.Peer-Reviewed Original ResearchT93 Readiness to Implement Contingency Management to Promote PrEP Initiation and Adherence Among People who Inject Drugs
Viera A, Pickering E, Sung M, Bailey G, Buchelli M, Davidson D, Jenkins M, John B, Kolakowski J, Maier L, Porter E, Perez O, Edelman E, Rash C. T93 Readiness to Implement Contingency Management to Promote PrEP Initiation and Adherence Among People who Inject Drugs. Drug And Alcohol Dependence 2024, 260: 110542. DOI: 10.1016/j.drugalcdep.2023.110542.Peer-Reviewed Original Research“Recovery is about change, so you have to change everything”: Exploring the evolution of recovery capital among women in substance use disorder treatment
Jadovich E, Viera A, Edelman E, Muilenburg J, Kershaw T. “Recovery is about change, so you have to change everything”: Exploring the evolution of recovery capital among women in substance use disorder treatment. SSM - Qualitative Research In Health 2024, 5: 100422. DOI: 10.1016/j.ssmqr.2024.100422.Peer-Reviewed Original ResearchSubstance use disorder treatmentRecovery capitalSecondary qualitative analysis of dataDisorder treatmentNon-clinical interventionsCommunity capitalSubstance use disordersSecondary qualitative analysisSubstance use disorder recoveryIndirect effects of treatmentExperiences of womenEffects of treatmentSubstance use researchRecovery capital frameworkAddiction researchQualitative analysis of dataStudy time pointsThematic analysisClinical pathwayParticipants' experiencesTreatment programsDisorder recoveryWomen's experiencesCapital frameworkCapital developmentImplementation of Opioid Safety Efforts: Influence of Academic Detailing on Adverse Outcomes Among Patients in the Veterans Health Administration.
Williams E, Frost M, Bounthavong M, Edmonds A, Lau M, Edelman E, Harvey M, Christopher M. Implementation of Opioid Safety Efforts: Influence of Academic Detailing on Adverse Outcomes Among Patients in the Veterans Health Administration. Substance Use & Addiction Journal 2024, 29767342241243309. PMID: 38634339, DOI: 10.1177/29767342241243309.Peer-Reviewed Original ResearchVeterans Health AdministrationAcademic detailingAll-cause mortalityInpatient admissionsED visitsHealth AdministrationVA electronic health recordOpioid poisoningEmergency departmentOdds of all-cause mortalityElectronic health recordsRates of inpatient admissionsAssociated with decreased all-cause mortalityPatients prescribed long-term opioidsInterrupted time series analysisIncreased inpatient hospitalizationsOpioid-related outcomesOverdose prevention initiativesLong-term opioidsIncreasing incidence ratesLong-term opioid prescriptionsPatient-level dataObservational cohort of patientsHealth recordsAD implementationDiscordance Between Insurance Coverage of Antiviral Medications and Nicotine Replacement Therapy Among Individuals With Human Immunodeficiency Virus Who Smoke
Bernstein S, Yager J, Sigel K, Porter E, Do T, Payne E, Bold K, Ledgerwood D, Edelman E. Discordance Between Insurance Coverage of Antiviral Medications and Nicotine Replacement Therapy Among Individuals With Human Immunodeficiency Virus Who Smoke. Journal Of Addiction Medicine 2024, 18: 404-407. PMID: 38606851, PMCID: PMC11290992, DOI: 10.1097/adm.0000000000001302.Peer-Reviewed Original ResearchNicotine replacement therapyHuman immunodeficiency virusTobacco use disorderAntiretroviral therapyReplacement therapyTobacco useImmunodeficiency virusCoverage of antiretroviral therapyInsurance coverageSecondary analysis of dataUse disorderManaged care planOut-of-pocketMandated insurance coverageCare planningEfficacy of antiviralsRandomized clinical trialsPharmacy benefit managersInsurance barriersMedication prescriptionsSecondary analysisTracking formParticipation AssessmentAntiviral medicationsPWHPriorities for HIV and chronic pain research: results from a survey of individuals with lived experience
Robinson-Papp J, Lawrence S, Wadley A, Scott W, George M, Josh J, O’Brien K, Price C, Uebelacker L, Edelman E, Evangeli M, Goodin B, Harding R, Nkhoma K, Parker R, Sabin C, Slawek D, Tsui J, Merlin J. Priorities for HIV and chronic pain research: results from a survey of individuals with lived experience. AIDS Care 2024, ahead-of-print: 1-11. PMID: 38588701, DOI: 10.1080/09540121.2024.2334358.Peer-Reviewed Original ResearchChronic painOptimal management of painSocial health factorsExperience of HIVSymptoms of anxietyManagement of painWeb-based surveyChronic pain researchMultisite painSurvey of individualsHealth factorsPain treatmentTreatment cost-effectivenessUS-based respondentsTask ForceGlobal Task ForceResearch prioritiesSurvey responsesPain researchMedian numberPainHIVOptimal managementTreatment individualizationAddiction treatmentAlcohol-Related Care Among Veterans With Unhealthy Alcohol Use: The Role of Long-Term Opioid Therapy Receipt
Joudrey P, Wang M, DeRycke E, Williams E, Edelman E. Alcohol-Related Care Among Veterans With Unhealthy Alcohol Use: The Role of Long-Term Opioid Therapy Receipt. Journal Of Addiction Medicine 2024, 18: 293-299. PMID: 38533996, PMCID: PMC11150097, DOI: 10.1097/adm.0000000000001291.Peer-Reviewed Original ResearchUnhealthy alcohol useAlcohol-related careLong-term opioid therapyBrief interventionOpioid receiptAlcohol useReceipt of alcohol-related careReceipt of brief interventionVeterans Health Administration careRates of brief interventionDocumented brief interventionNational cohort of veteransWomen Veterans Cohort StudyCohort of veteransPositive alcohol screensAlcohol screeningIntervention receiptAdministration carePositive screenConsumption questionnaireOpioid prescribingNational cohortTherapy receiptCohort studyCarePerspectives regarding cannabis use: Results from a qualitative study of individuals engaged in substance use treatment in Georgia and Connecticut
Warnock C, Ondrusek A, Edelman E, Kershaw T, Muilenburg J. Perspectives regarding cannabis use: Results from a qualitative study of individuals engaged in substance use treatment in Georgia and Connecticut. Drug And Alcohol Dependence Reports 2024, 11: 100228. PMID: 38585142, PMCID: PMC10997993, DOI: 10.1016/j.dadr.2024.100228.Peer-Reviewed Original ResearchSubstance use disordersCannabis useQualitative study of individualsSubstance use disorder treatment outcomesTreatment-related consequencesSemi-structured interviewsSubstance use treatmentSubstance use initiationStudy of individualsImprove healthPrescription medicationsQualitative studyHealth challengesMedicine beliefsPerceived cannabisTreatment cliniciansPeer perceptionsEntering treatmentAt-riskCannabisSocial servicesStudy objectiveYoung adulthoodInterviewsHealthAvailability of substance use screening and treatment within HIV clinical sites across seven geographic regions within the IeDEA consortium
Lancaster K, Stockton M, Remch M, Wester C, Nash D, Brazier E, Adedimeji A, Finlayson R, Freeman A, Hogan B, Kasozi C, Kwobah E, Kulzer J, Merati T, Tine J, Poda A, Succi R, Twizere C, Tlali M, von Groote P, Edelman E, Parcesepe A, Consortium I. Availability of substance use screening and treatment within HIV clinical sites across seven geographic regions within the IeDEA consortium. International Journal Of Drug Policy 2024, 124: 104309. PMID: 38228025, PMCID: PMC10939808, DOI: 10.1016/j.drugpo.2023.104309.Peer-Reviewed Original ResearchAlcohol use disorder screeningHIV clinical sitesHIV care settingsProportion of clinicsSubstance use disordersAlcohol use disorderBrief interventionHIV careCare settingsClinical sitesSubstance use disorder screeningTreatment availabilityNegative impact of substance useHIV clinical settingsAvailability of screeningReferral to treatmentInternational epidemiology DatabasesHigh-income countiesImpact of substance useLower-middle-income countriesTreat alcohol use disorderUpper-middle income countriesLow-income countriesEpidemiological databasePrevalence estimatesPerspectives of clinical stakeholders and patients from four VA liver clinics to tailor practice facilitation for implementing evidence-based alcohol-related care
Soyer E, Frost M, Fletcher O, Ioannou G, Tsui J, Edelman E, Weiner B, Bachrach R, Chen J, Williams E. Perspectives of clinical stakeholders and patients from four VA liver clinics to tailor practice facilitation for implementing evidence-based alcohol-related care. Addiction Science & Clinical Practice 2024, 19: 3. PMID: 38200496, PMCID: PMC10782537, DOI: 10.1186/s13722-023-00429-3.Peer-Reviewed Original ResearchConceptsConsolidated Framework for Implementation ResearchAlcohol-related careVeterans Health AdministrationRapid Assessment ProcessClinical stakeholdersPatient participationImplement interventionsBackgroundUnhealthy alcohol useLiver clinicEvidence-based strategiesClinical settingPractice facilitationProvider beliefsImplementation researchHealth AdministrationMethodsData collectionClinical resourcesQualitative interviewsAlcohol use disorderEducation-basedCareAlcohol useMedical CenterPreference-basedRelationship-based
2023
Expanding the Use of Medications for Alcohol Use Disorder: Lessons from the Proliferation of Anti-obesity Medications
Bernstein E, Moreno J, Edelman E. Expanding the Use of Medications for Alcohol Use Disorder: Lessons from the Proliferation of Anti-obesity Medications. Journal Of General Internal Medicine 2023, 39: 1233-1235. PMID: 38087177, PMCID: PMC11116289, DOI: 10.1007/s11606-023-08565-x.Peer-Reviewed Original ResearchPerspectives on unhealthy alcohol use among men who have sex with men prescribed HIV pre-exposure prophylaxis: A qualitative study
Strong S, Oldfield B, van den Berg J, Cole C, Biegacki E, Ogbuagu O, Virata M, Chan P, Edelman E. Perspectives on unhealthy alcohol use among men who have sex with men prescribed HIV pre-exposure prophylaxis: A qualitative study. Preventive Medicine Reports 2023, 37: 102553. PMID: 38282665, PMCID: PMC10810836, DOI: 10.1016/j.pmedr.2023.102553.Peer-Reviewed Original ResearchUnhealthy alcohol usePre-exposure prophylaxisAlcohol reduction interventionsAlcohol useHIV pre-exposure prophylaxisOral pre-exposure prophylaxisAcquisition of HIVAlcohol-related harmPrEP adherencePrEP careTreatment optionsOral formulationReduction interventionsPrEP programMSMPrEPProphylaxisHIVMultimodal approachMenCareAdherenceInterventionSexUnited StatesIntegrating stakeholder feedback into the design of a peer-delivered primary care wellness program: A rapid qualitative study
Johnson E, Possemato K, Chinman M, True G, Hedges J, Hampton B, Edelman E, Maisto S. Integrating stakeholder feedback into the design of a peer-delivered primary care wellness program: A rapid qualitative study. BMC Health Services Research 2023, 23: 1370. PMID: 38062433, PMCID: PMC10701982, DOI: 10.1186/s12913-023-10324-x.Peer-Reviewed Original ResearchConceptsBehavioral health concernsPrimary careHealth concernWhole Health modelPrimary care settingBehavioral health treatmentCare settingsSemi-structured qualitative interviewsHealth treatmentMaximum variation strategyRapid qualitative studyConsolidated FrameworkNew interventionsStakeholder feedbackVA staffWellness programsHealth modelImplementation researchInitial trialCareNational sampleFrontline staffInterventionVeteransStaff membersThe Association of Prescribed Opioids and Incident Cardiovascular Disease
Sung M, Eden S, Becker W, Crystal S, Duncan M, Gordon K, Kerns R, Kundu S, Freiberg M, So-Armah K, Edelman E. The Association of Prescribed Opioids and Incident Cardiovascular Disease. Journal Of Pain 2023, 25: 104436. PMID: 38029949, PMCID: PMC11058015, DOI: 10.1016/j.jpain.2023.11.019.Peer-Reviewed Original ResearchIncident cardiovascular diseaseModifiable CVD risk factorsCVD risk factorsHuman immunodeficiency virusCardiovascular diseasePrescribed opioidsOpioid receiptRisk factorsUse disordersCox proportional hazards regression modelVeterans Aging Cohort StudyVeterans Health Administration (VHA) carePropensity scoreProportional hazards regression modelsCVD incidence ratesPrescription opioid exposureIncident CVD eventsPrevalence of hypertensionAging Cohort StudyHigher opioid dosesOpioid use disorderHazards regression modelsNational prospective cohortVeterans Administration dataCocaine use disorderPrevalence and Correlates of Physical Inactivity Among Individuals with HIV During the First COVID-19 Wave: A Cross-sectional Survey
Harsono D, Deng Y, Chung S, Barakat L, Friedland G, Villanueva M, Yager J, Justen M, Edelman E. Prevalence and Correlates of Physical Inactivity Among Individuals with HIV During the First COVID-19 Wave: A Cross-sectional Survey. AIDS And Behavior 2023, 28: 1531-1545. PMID: 37824037, DOI: 10.1007/s10461-023-04170-5.Peer-Reviewed Original ResearchPhysical activity guidelinesPhysical inactivityPhysical activityDetectable HIV viral loadSelf-reported physical activitySample of PWHHIV viral loadPhysical activity levelsUnhealthy alcohol useFirst COVID-19 waveImproved health outcomesCross-sectional surveyHIV clinicCOVID-19 waveActivity guidelinesAdjusted analysisCOVID-19 transmissionViral loadTobacco useCoping strategiesSedentary lifestyleLower oddsPsychological coping strategiesHealth outcomesDisease controlCannabis use disorder and adverse cardiovascular outcomes: A population‐based retrospective cohort analysis of adults from Alberta, Canada
Bahji A, Hathaway J, Adams D, Crockford D, Edelman E, Stein M, Patten S. Cannabis use disorder and adverse cardiovascular outcomes: A population‐based retrospective cohort analysis of adults from Alberta, Canada. Addiction 2023, 119: 137-148. PMID: 37766508, DOI: 10.1111/add.16337.Peer-Reviewed Original ResearchConceptsCVD eventsRisk ratioIncident CVDPopulation-based retrospective cohort analysisPopulation-based retrospective cohort studyAdverse cardiovascular disease (CVD) eventsAdverse cardiovascular disease outcomesAdverse CVD eventsGreater risk ratioIncident CVD eventsRetrospective cohort studyAdverse cardiovascular outcomesCardiovascular disease eventsRetrospective cohort analysisCardiovascular disease outcomesMental health comorbiditiesTime of presentationAdministrative health databasesHealth service usePrescription medication useCannabis use disorderMantel-Haenszel techniqueHealth care servicesPoisson regression modelsYear of birth