2024
Corrigendum to “Extensive transmission of SARS-CoV-2 BQ.1* variant in a population with high levels of hybrid immunity: A prevalence survey” [International Journal of Infectious Diseases 139 (2024) 159-167]
Ticona J, Xiao M, Li D, Nery N, Hitchings M, Belitardo E, Fofana M, Victoriano R, Cruz J, de Moraes L, Strobel I, Silva J, do Aragão Filho A, Ribeiro G, Reis M, Costa F, Khouri R, Ko A, Cummings D. Corrigendum to “Extensive transmission of SARS-CoV-2 BQ.1* variant in a population with high levels of hybrid immunity: A prevalence survey” [International Journal of Infectious Diseases 139 (2024) 159-167]. International Journal Of Infectious Diseases 2024, 141: 106964. PMID: 38452689, PMCID: PMC10927614, DOI: 10.1016/j.ijid.2024.02.007.Peer-Reviewed Original ResearchOverestimation of Severe Acute Respiratory Syndrome Coronavirus 2 Household Transmission in Settings of High Community Transmission: Insights From an Informal Settlement Community in Salvador, Brazil
Ticona J, Nery N, Hitchings M, Belitardo E, Fofana M, Dorión M, Victoriano R, Cruz J, Santana J, de Moraes L, Cardoso C, Ribeiro G, Reis M, Khouri R, Costa F, Ko A, Cummings D. Overestimation of Severe Acute Respiratory Syndrome Coronavirus 2 Household Transmission in Settings of High Community Transmission: Insights From an Informal Settlement Community in Salvador, Brazil. Open Forum Infectious Diseases 2024, 11: ofae065. PMID: 38516384, PMCID: PMC10957159, DOI: 10.1093/ofid/ofae065.Peer-Reviewed Original ResearchSARS-CoV-2Household transmissionRT-PCR positive casesSecondary attack rateAttack rateSARS-CoV-2 infectionSARS-CoV-2 Omicron variantRisk of infectionCommunity acquisitionTherapeutic optionsCOVID-19-related symptomsCase-finding studyHousehold contactsAcquisition of SARS-CoV-2Increased riskSymptom onsetSecondary infectionBooster vaccinationSevere outcomesBiweekly visitsHighest attack rateRT-PCRInfectionCOVID-19 severe outcomesOmicron BA
2023
Extensive transmission of SARS-CoV-2 BQ.1* variant in a population with high levels of hybrid immunity: A prevalence survey
Ticona J, Xiao M, Li D, Nery N, Hitchings M, Belitardo E, Fofana M, Victoriano R, Cruz J, de Moraes L, Strobel I, Silva J, do Aragão Filho A, Ribeiro G, Reis M, Costa F, Khouri R, Ko A, Cummings D. Extensive transmission of SARS-CoV-2 BQ.1* variant in a population with high levels of hybrid immunity: A prevalence survey. International Journal Of Infectious Diseases 2023, 139: 159-167. PMID: 38070701, PMCID: PMC10784150, DOI: 10.1016/j.ijid.2023.11.039.Peer-Reviewed Original Research
2022
Association between primary or booster COVID-19 mRNA vaccination and Omicron lineage BA.1 SARS-CoV-2 infection in people with a prior SARS-CoV-2 infection: A test-negative case–control analysis
Lind M, Robertson A, Silva J, Warner F, Coppi A, Price N, Duckwall C, Sosensky P, Di Giuseppe E, Borg R, Fofana M, Ranzani O, Dean N, Andrews J, Croda J, Iwasaki A, Cummings D, Ko A, Hitchings M, Schulz W. Association between primary or booster COVID-19 mRNA vaccination and Omicron lineage BA.1 SARS-CoV-2 infection in people with a prior SARS-CoV-2 infection: A test-negative case–control analysis. PLOS Medicine 2022, 19: e1004136. PMID: 36454733, PMCID: PMC9714718, DOI: 10.1371/journal.pmed.1004136.Peer-Reviewed Original ResearchConceptsSARS-CoV-2 infectionBooster vaccinationPrior infectionOmicron infectionPrimary vaccinationMRNA vaccinationOdds ratioAcute respiratory syndrome coronavirus 2 infectionSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infectionPrior SARS-CoV-2 infectionTest-negative case-control analysisYale New Haven Health SystemTest-negative case-control studyCOVID-19 mRNA vaccinationSyndrome coronavirus 2 infectionOmicron variant infectionPrior infection statusCoronavirus 2 infectionCase-control studyCase-control analysisOdds of infectionRisk of infectionRace/ethnicityBooster dosesDate of testStructural factors associated with SARS-CoV-2 infection risk in an urban slum setting in Salvador, Brazil: A cross-sectional survey
Fofana MO, Nery N, Ticona J, de Andrade Belitardo EMM, Victoriano R, Anjos RO, Portilho MM, de Santana MC, dos Santos LL, de Oliveira D, Cruz JS, Muenker MC, Khouri R, Wunder EA, Hitchings MDT, Johnson O, Reis MG, Ribeiro GS, Cummings DAT, Costa F, Ko AI. Structural factors associated with SARS-CoV-2 infection risk in an urban slum setting in Salvador, Brazil: A cross-sectional survey. PLOS Medicine 2022, 19: e1004093. PMID: 36074784, PMCID: PMC9499230, DOI: 10.1371/journal.pmed.1004093.Peer-Reviewed Original ResearchConceptsSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infectionAcute respiratory syndrome coronavirus 2 infectionSARS-CoV-2 infection riskUrban slumsSyndrome coronavirus 2 infectionSARS-CoV-2 seroprevalenceSARS-CoV-2 incidenceCoronavirus 2 infectionCross-sectional serosurveyMain outcome measuresUrban slum populationPresence of IgGSARS-CoV-2 spike proteinUrban slum communityCross-sectional surveyUrban slum residentsCumulative incidenceMedian ageRisk factorsOutcome measuresStudy populationHigh seroprevalenceMedian dailyPandemic waveGender distributionReliable estimation of SARS-CoV-2 anti-spike protein IgG titers from single dilution optical density values in serologic surveys
Belitardo E, Nery N, Ticona J, Portilho MM, Mello IO, Ribeiro GS, Reis MG, Costa F, Cummings DAT, Ko AI, Fofana MO. Reliable estimation of SARS-CoV-2 anti-spike protein IgG titers from single dilution optical density values in serologic surveys. Diagnostic Microbiology And Infectious Disease 2022, 104: 115807. PMID: 36162285, PMCID: PMC9428330, DOI: 10.1016/j.diagmicrobio.2022.115807.Peer-Reviewed Original ResearchConceptsSARS-CoV-2 incidenceCommunity-based cohortPopulation-level immunitySARS-CoV-2Large-scale serosurveysELISA optical densityIgG titersIgG ELISAPandemic evolvesSerologic surveyTitersOptical density valuesPopulation-level changesSerosurveyImmunitySingle dilutionSerial dilutionsNODCohortIncidenceELISASerum
2021
The Deepest Cuts
Fofana MO. The Deepest Cuts. Annals Of Emergency Medicine 2021, 78: 453-454. PMID: 34420558, DOI: 10.1016/j.annemergmed.2021.03.011.Peer-Reviewed Original ResearchWillingness to Get the COVID-19 Vaccine among Residents of Slum Settlements
Ticona J, Nery N, Victoriano R, Fofana MO, Ribeiro GS, Giorgi E, Reis MG, Ko AI, Costa F. Willingness to Get the COVID-19 Vaccine among Residents of Slum Settlements. Vaccines 2021, 9: 951. PMID: 34579188, PMCID: PMC8472908, DOI: 10.3390/vaccines9090951.Peer-Reviewed Original ResearchVaccine hesitancyCOVID-19 vaccine acceptanceCOVID-19 vaccine hesitancyImportance of vaccinationCOVID-19 infectionCOVID-19 vaccinePotential side effectsCOVID-19Vaccine efficacyCOVID-19 casesVaccine acceptanceVaccine intentionsGeneral populationHigh incidenceSpecific treatmentSide effectsHealth historySalvador-BrazilMultivariate analysisYounger ageVaccineSlum residentsSlum settingsVaccinationSlum communitiesRacial Discrimination from Patients: Institutional Strategies to Establish Respectful Emergency Department Environments
Chary A, Fofana M, Kohli H. Racial Discrimination from Patients: Institutional Strategies to Establish Respectful Emergency Department Environments. Western Journal Of Emergency Medicine 2021, 22: 898-902. PMID: 35354011, PMCID: PMC8328184, DOI: 10.5811/westjem.2021.3.51582.Peer-Reviewed Original ResearchTime and time again: the reincarnations of coerced sterilisation
Fofana MO. Time and time again: the reincarnations of coerced sterilisation. Journal Of Medical Ethics 2021, 48: 805-809. PMID: 34127527, DOI: 10.1136/medethics-2020-106924.Peer-Reviewed Original Research
2020
Decolonising global health in the time of COVID-19
Fofana MO. Decolonising global health in the time of COVID-19. Global Public Health 2020, 16: 1155-1166. PMID: 33370211, DOI: 10.1080/17441692.2020.1864754.Peer-Reviewed Original ResearchConceptsCovid-OrganicsContemporary documentary sourcesEffective traditional remediesHistorical sourcesInequitable power structuresColonial inheritanceDocumentary sourcesHistorical contextFrench researchersColonialityPower structuresExternal actorsPersistent influenceAfricaColonialismEssayRhetoricReflectionScandalsMarginalisationActorsClaimsControversyEntrenchExploitation
2017
Reply to Anthony et al., “Protecting Pyrazinamide, a Priority for Improving Outcomes in Multidrug-Resistant Tuberculosis Treatment”
Fofana M, Dowdy D. Reply to Anthony et al., “Protecting Pyrazinamide, a Priority for Improving Outcomes in Multidrug-Resistant Tuberculosis Treatment”. Antimicrobial Agents And Chemotherapy 2017, 61: 10.1128/aac.00427-17. PMID: 28539499, PMCID: PMC5444152, DOI: 10.1128/aac.00427-17.Commentaries, Editorials and LettersA Multistrain Mathematical Model To Investigate the Role of Pyrazinamide in the Emergence of Extensively Drug-Resistant Tuberculosis
Fofana MO, Shrestha S, Knight GM, Cohen T, White RG, Cobelens F, Dowdy DW. A Multistrain Mathematical Model To Investigate the Role of Pyrazinamide in the Emergence of Extensively Drug-Resistant Tuberculosis. Antimicrobial Agents And Chemotherapy 2017, 61: 10.1128/aac.00498-16. PMID: 27956422, PMCID: PMC5328532, DOI: 10.1128/aac.00498-16.Peer-Reviewed Original ResearchMeSH KeywordsAntitubercular AgentsBayes TheoremBiological AvailabilityComputer SimulationDrug Administration ScheduleDrug Resistance, Multiple, BacterialExtensively Drug-Resistant TuberculosisFluoroquinolonesHumansMicrobial Sensitivity TestsModels, StatisticalMycobacterium tuberculosisPyrazinamideRifampinTuberculosis, PulmonaryConceptsCompanion drugsExtensively Drug-Resistant TuberculosisSecond-line treatmentFirst-line treatmentSecond-line regimensDrug-resistant tuberculosisUse of pyrazinamideExtensive drug resistanceDrug resistance dataEmergence of strainsEmergence of mutationsXDR-TBSequential regimensHIV infectionAlternative drugsResistance amplificationPyrazinamide resistanceProlonged treatmentCombination antimicrobialsDrug resistanceInfectious diseasesPrevalenceProportion of simulationsAppropriate useRegimens
2015
Burden of transmitted multidrug resistance in epidemics of tuberculosis: a transmission modelling analysis
Kendall EA, Fofana MO, Dowdy DW. Burden of transmitted multidrug resistance in epidemics of tuberculosis: a transmission modelling analysis. The Lancet Respiratory Medicine 2015, 3: 963-972. PMID: 26597127, PMCID: PMC4684734, DOI: 10.1016/s2213-2600(15)00458-0.Peer-Reviewed Original ResearchConceptsMDR tuberculosisDynamic transmission modelPerson transmissionTuberculosis incidenceTuberculosis treatmentTuberculosis epidemicMDR tuberculosis casesDrug-susceptible tuberculosisFirst-line treatmentHigh-burden settingsMultidrug-resistant tuberculosisEpidemic of tuberculosisDrug regimensTuberculosis casesMDR prevalenceTuberculosis notificationsTuberculosis prevalenceNotification dataMDR acquisitionMDR transmissionTuberculosisMultidrug resistanceDe novo mutationsMelinda Gates FoundationNational InstituteThe Distribution of Fitness Costs of Resistance-Conferring Mutations Is a Key Determinant for the Future Burden of Drug-Resistant Tuberculosis: A Model-Based Analysis
Knight GM, Colijn C, Shrestha S, Fofana M, Cobelens F, White RG, Dowdy DW, Cohen T. The Distribution of Fitness Costs of Resistance-Conferring Mutations Is a Key Determinant for the Future Burden of Drug-Resistant Tuberculosis: A Model-Based Analysis. Clinical Infectious Diseases 2015, 61: s147-s154. PMID: 26409276, PMCID: PMC4583567, DOI: 10.1093/cid/civ579.Peer-Reviewed Original ResearchDevelopment of global health education at Johns Hopkins University School of Medicine: a student-driven initiative
Moran D, Edwardson J, Cuneo CN, Tackett S, Aluri J, Kironji A, Cox J, Carroll B, Lie E, Fofana M, Bollinger RC, Ziegelstein RC, Chen CC. Development of global health education at Johns Hopkins University School of Medicine: a student-driven initiative. Medical Education Online 2015, 20: 28632. PMID: 26220909, PMCID: PMC4518163, DOI: 10.3402/meo.v20.28632.Peer-Reviewed Original ResearchConceptsGlobal health educationJohns Hopkins University SchoolHealth educationUniversity SchoolStudent-driven initiativesFirst-year studentsFormal educational curriculumGlobal health experiencesGlobal health electivesSchool of MedicineGlobal health programsLearning opportunitiesInterprofessional programEducational curriculumEducational opportunitiesMedical schoolsMedical studentsEducational websitesStudentsSchoolsInternational electivesInterprofessional collaborationSupportive administrationEducationJohns Hopkins Experience
2014
Gaps in predeparture training and postexperience debriefing in global health experiences: A survey of health professions students
Kironji A, Aluri J, Decamp M, Carroll B, Cox J, Fofana M, Lie E, Moran D, Tackett S, Chen C. Gaps in predeparture training and postexperience debriefing in global health experiences: A survey of health professions students. Annals Of Global Health 2014, 80: 166-167. DOI: 10.1016/j.aogh.2014.08.031.Peer-Reviewed Original ResearchDrivers and Trajectories of Resistance to New First-Line Drug Regimens for Tuberculosis
Shrestha S, Knight GM, Fofana M, Cohen T, White RG, Cobelens F, Dowdy DW. Drivers and Trajectories of Resistance to New First-Line Drug Regimens for Tuberculosis. Open Forum Infectious Diseases 2014, 1: ofu073. PMID: 25734143, PMCID: PMC4281792, DOI: 10.1093/ofid/ofu073.Peer-Reviewed Original ResearchDrug-resistant TBTreatment of tuberculosisNew drug regimenTransmission fitnessDrug regimensDrug regimenTreatment successDrug-susceptible TBAppropriate second-line therapyDR-TB prevalenceSecond-line therapyDrug resistance trendsTreatment success rateHigher treatment successNovel drug regimensEmergence of resistancePopulation-level dataTB regimensShort-term surveillanceDS-TBNew regimenClinical trialsEarly diagnosisRegimensDrug resistancePopulation-Level Impact of Shorter-Course Regimens for Tuberculosis: A Model-Based Analysis
Fofana MO, Knight GM, Gomez GB, White RG, Dowdy DW. Population-Level Impact of Shorter-Course Regimens for Tuberculosis: A Model-Based Analysis. PLOS ONE 2014, 9: e96389. PMID: 24816692, PMCID: PMC4015982, DOI: 10.1371/journal.pone.0096389.Peer-Reviewed Original ResearchConceptsShort-course regimensTB incidenceTreatment completionTreatment successFirst-line treatment regimensFour-month regimenFour-month regimensLower treatment completionProportion of patientsPopulation-level incidenceSix-month therapyGlobal tuberculosis incidenceDynamic transmission modelPopulation-level transmissionCourse regimensTB diseaseTB patientsNew regimensRelapse rateTB mortalityTB transmissionTreatment regimensTuberculosis incidenceClinical trialsRegimens
2013
The spectre of race in American medicine
Fofana MO. The spectre of race in American medicine. Medical Humanities 2013, 39: 137. PMID: 23988563, PMCID: PMC4131435, DOI: 10.1136/medhum-2013-010374.Peer-Reviewed Original ResearchConceptsUse of raceAmerican medicineHistory of slaveryInstitution of slaveryHistorical injusticesRacial hierarchyContemporary debatesContemporary examplesPast abuseSlaveryReflexive useRacePastTremendous influenceDebateContemporary medicineMedicine todayToday's physiciansBiological conceptsHistorySpectreInjusticeTodayWayConcept