2024
Family history of psychiatric conditions and development of siblings of children with autism
Bellia G, Chang J, Liew Z, Vernetti A, Macari S, Powell K, Chawarska K. Family history of psychiatric conditions and development of siblings of children with autism. Autism Research 2024 PMID: 38896553, DOI: 10.1002/aur.3175.Peer-Reviewed Original ResearchSiblings of childrenNeuropsychiatric disordersFamilies of childrenFamily history of schizophreniaYounger siblings of childrenHistory of psychiatric conditionsHistory of schizophreniaYounger siblingsAssess autism symptomsNonverbal IQAutism symptomsBipolar disorderIntellectual disabilityPsychiatric conditionsSubclinical symptomsAdaptive skillsSocial affectAdaptive functioningAutismFamily historyParent interviewsFamily factorsMultiple regression analysisDevelopmental outcomesDisorders
2022
Elevated symptoms of executive dysfunction predict lower adaptive functioning in 3‐year‐olds with autism spectrum disorder
Powell K, Macari S, Brennan‐Wydra E, Feiner H, Butler M, Fortes D, Boxberger A, Torres‐Viso M, Morgan C, Lyons M, Chawarska K. Elevated symptoms of executive dysfunction predict lower adaptive functioning in 3‐year‐olds with autism spectrum disorder. Autism Research 2022, 15: 1336-1347. PMID: 35388596, PMCID: PMC9253075, DOI: 10.1002/aur.2715.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderDaily living skillsExecutive functioningEF deficitsAdaptive functioningSpectrum disorderLiving skillsExecutive functioning (EF) deficitsAutism severity scoresLower adaptive functioningCognitive flexibilityAtypical developmentDevelopmental presentationExecutive dysfunctionAdaptive skillsNonverbal functioningVABS-IIElevated symptomsAge threeToddlersLong-term detrimental impactDevelopmental quotientFunctioningChronological ageSymptom severity
2016
Non‐ASD outcomes at 36 months in siblings at familial risk for autism spectrum disorder (ASD): A baby siblings research consortium (BSRC) study
Charman T, Young GS, Brian J, Carter A, Carver LJ, Chawarska K, Curtin S, Dobkins K, Elsabbagh M, Georgiades S, Hertz‐Picciotto I, Hutman T, Iverson JM, Jones EJ, Landa R, Macari S, Messinger DS, Nelson CA, Ozonoff S, Saulnier C, Stone WL, Tager‐Flusberg H, Webb SJ, Yirmiya N, Zwaigenbaum L. Non‐ASD outcomes at 36 months in siblings at familial risk for autism spectrum disorder (ASD): A baby siblings research consortium (BSRC) study. Autism Research 2016, 10: 169-178. PMID: 27417857, PMCID: PMC5993543, DOI: 10.1002/aur.1669.Peer-Reviewed Original ResearchConceptsAutism Diagnostic Observation ScheduleAutism spectrum disorderHigh-risk siblingsLow-risk controlsBroader autism phenotypeModerate language delayAdaptive functioningASD symptomsLanguage delayVineland Adaptive Behavior ScalesLower adaptive functioningAge 3 yearsAutism Diagnostic InterviewProportion of toddlersAdaptive behavior outcomesAdaptive Behavior ScalesOngoing clinical monitoringAutism phenotypeMullen ScalesSpectrum disorderObservation ScheduleEarly learningBehavioral outcomesElevated scoresDevelopmental outcomes
2013
Gaze Response to Dyadic Bids at 2 Years Related to Outcomes at 3 Years in Autism Spectrum Disorders: A Subtyping Analysis
Campbell DJ, Shic F, Macari S, Chawarska K. Gaze Response to Dyadic Bids at 2 Years Related to Outcomes at 3 Years in Autism Spectrum Disorders: A Subtyping Analysis. Journal Of Autism And Developmental Disorders 2013, 44: 431-442. PMID: 23877749, PMCID: PMC3900601, DOI: 10.1007/s10803-013-1885-9.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderSpectrum disorderChild-directed speechVisual responsesDirect gazeAdaptive functioningSocial scenesSpeaker's mouthHigh functioningBetter attentionCuesToddlersFunctioningLimited attentionEarly predictorAttentionDisordersSpeechSceneGazeYears of ageLanguageEngagementOutcomesMeaningful approach
2011
Early Generalized Overgrowth in Boys With Autism
Chawarska K, Campbell D, Chen L, Shic F, Klin A, Chang J. Early Generalized Overgrowth in Boys With Autism. JAMA Psychiatry 2011, 68: 1021-1031. PMID: 21969460, PMCID: PMC4878118, DOI: 10.1001/archgenpsychiatry.2011.106.Peer-Reviewed Original ResearchConceptsLower adaptive functioningAdaptive functioning levelPervasive developmental disorderCognitive functioningAdaptive functioningCognitive featuresSocial deficitsHC growthAge-related changesUniversity-based clinicAutismFunctioning levelsAge 24 monthsAutistic disorderClinical groupsDevelopmental disordersDevelopmental problemsFunctioningDevelopmental delayBoysAge 2 yearsGeneralized overgrowthOvergrowth patternGreater severityFirst year