2024
Multimorbidity and associated informal care receiving characteristics for US older adults: a latent class analysis
Liu R, Nagel C, Chen S, Newsom J, Allore H, Quiñones A. Multimorbidity and associated informal care receiving characteristics for US older adults: a latent class analysis. BMC Geriatrics 2024, 24: 571. PMID: 38956501, PMCID: PMC11221032, DOI: 10.1186/s12877-024-05158-z.Peer-Reviewed Original ResearchConceptsNational Health and Aging Trends StudyMultimorbidity patternsCare needsOlder adultsSelf-careInformal careLatent class analysisCare receiver characteristicsCombinations of multimorbidityPerson-centered carePatterns of multimorbidityDifferential care needsUS older adultsAssociated with lower oddsAssociated with higher oddsGroup of older adultsMultinomial logistic regression modelModerate cognitive impairmentClass analysisLogistic regression modelsInformal caregiversBackgroundOlder adultsCare recipientsMultimorbidity groupsChronic conditionsMultimorbidity Patterns, Hospital Uses and Mortality by Race and Ethnicity Among Oldest-Old Patients
Cho J, Allore H, Rahimighazikalayeh G, Vaughn I. Multimorbidity Patterns, Hospital Uses and Mortality by Race and Ethnicity Among Oldest-Old Patients. Journal Of Racial And Ethnic Health Disparities 2024, 1-10. PMID: 38381325, DOI: 10.1007/s40615-024-01929-x.Peer-Reviewed Original ResearchOldest-old patientsClinic visitsAssociated with EDHealthcare systemEmergency departmentPatterns of multimorbidityHealthcare service utilizationIntegrated healthcare systemGeneralized estimating equationsRacial-ethnic groupsMultimorbidity patternsMultimorbidity clustersMinoritized patientsEmergency careService utilizationProportional hazards survival modelChronic conditionsOldest-oldHospital useDiverse patientsMultimorbidityAge-related risk factorsHospital servicesRace-ethnicityRacial-ethnic variationsProfile of Caregiving Activities and Association With Physical Health Among Dementia Spousal Caregivers
Cho J, Sands L, Stevens A, Allore H, Horstman M. Profile of Caregiving Activities and Association With Physical Health Among Dementia Spousal Caregivers. Innovation In Aging 2024, 8: igae017. PMID: 38524243, PMCID: PMC10960627, DOI: 10.1093/geroni/igae017.Peer-Reviewed Original ResearchSpousal caregivers of personsCaregivers of personsSpousal caregiversPhysical activityHealth indicatorsHealth-promoting behaviorsElectronic health recordsPhysical health indicatorsSelf-reported fatigueSleep disturbanceLow-intensity groupFrequency of healthCaregiving intensityCare recipientsCaregiving experiencePain interferenceCaregiving activitiesPhysical functionHealth behaviorsPromoting behaviorsHealth recordsChronic conditionsPhysical healthCaregiversEffective interventions
2023
PERSONALIZED AND TYPICAL CONCURRENT RISK: JOINT MODELS OF RECURRENT OUTCOMES AND MORTALITY BY RACE/ETHNICITY
Allore H, McAvay G, Vander Wyk B, Han L, Quiñones A. PERSONALIZED AND TYPICAL CONCURRENT RISK: JOINT MODELS OF RECURRENT OUTCOMES AND MORTALITY BY RACE/ETHNICITY. Innovation In Aging 2023, 7: 231-231. PMCID: PMC10736438, DOI: 10.1093/geroni/igad104.0759.Peer-Reviewed Original ResearchMultiple chronic conditionsChronic conditionsRisk factorsConcurrent riskSociodemographic risk factorsPoor health outcomesHuman Services initiativeHealthcare system policiesRace/ethnicityFunctional statusHigh riskHealth outcomesHealth statusHealth servicesAverage riskPatient trajectoriesPopulation subgroupsOutcomesRecurrent outcomesRiskCohort levelConcurrent outcomesRandom intercept termLongitudinal effectsMultiple outcomesCONTRIBUTION OF CHRONIC CONDITIONS TO MORTALITY: DIFFERENCES BY RACE AND ETHNICITY
Quiñones A, Elman M, McAvay G, Vander Wyk B, Nagel C, Allore H. CONTRIBUTION OF CHRONIC CONDITIONS TO MORTALITY: DIFFERENCES BY RACE AND ETHNICITY. Innovation In Aging 2023, 7: 763-764. PMCID: PMC10738322, DOI: 10.1093/geroni/igad104.2468.Peer-Reviewed Original ResearchNeurodegenerative conditionsLung diseasePreventative care servicesHealth care utilizationAverage attributable fractionNon-Hispanic whitesBlack older adultsRace/ethnicityCare utilizationChronic conditionsAttributable fractionCardiovascular diseaseCare servicesEthnic groupsSociodemographic characteristicsHealth disparitiesHispanic participantsMortalityOlder adultsDiseaseBlack participantsEthnic differencesDiabetesWhite participantsDementiaPROFILE OF CAREGIVING ACTIVITIES AND ASSOCIATION WITH PHYSICAL HEALTH AMONG DEMENTIA SPOUSAL CAREGIVERS
Cho J, Sands L, Stevens A, Allore H, Horstman M, Milius R, Hickey A. PROFILE OF CAREGIVING ACTIVITIES AND ASSOCIATION WITH PHYSICAL HEALTH AMONG DEMENTIA SPOUSAL CAREGIVERS. Innovation In Aging 2023, 7: 782-782. PMCID: PMC10736688, DOI: 10.1093/geroni/igad104.2526.Peer-Reviewed Original ResearchSleep disturbancesPhysical activityFamily caregiversHealth behaviorsSpousal caregiversHealth indicatorsPhysical healthHealth promotion behaviorsLess physical activityMore sleep disturbancesFrequency of healthPhysical health indicatorsElectronic health recordsPain interferenceChronic conditionsGeneral healthPhysical functioningPsychosocial distressPromotion behaviorsChi2 testHealth responsibilityDaily careAlzheimer's diseaseRelated dementiaCaregiving activitiesTHE EFFECT OF CHRONIC CONDITIONS ON DEPRESSIVE SYMPTOMS IS MODERATED BY SEXUAL MINORITY STATUS
Trubits E, Newsom J, Saucedo J, Botoseneanu A, Allore H, Nagel C, Dorr D, Quiñones A. THE EFFECT OF CHRONIC CONDITIONS ON DEPRESSIVE SYMPTOMS IS MODERATED BY SEXUAL MINORITY STATUS. Innovation In Aging 2023, 7: 797-798. PMCID: PMC10737157, DOI: 10.1093/geroni/igad104.2574.Peer-Reviewed Original ResearchSelf-rated healthGreater depressive symptomsChronic conditionsDepressive symptomsOlder adultsEffect of SRHGood self-rated healthRace/ethnicityMinority older adultsYears of educationSymptomsHealth disparitiesMental healthPhysical healthSM adultsAdultsRetirement StudyHealthSexual minority statusDirect effectParticipant sexSame effectGreater numberDisparitiesLATENT CLASSES OF MULTIMORBIDITY AND ASSOCIATED CARE-RECEIVING CHARACTERISTICS FOR US OLDER ADULTS
Liu M, Nagel C, Chen S, Kaye J, Allore H, Quiñones A. LATENT CLASSES OF MULTIMORBIDITY AND ASSOCIATED CARE-RECEIVING CHARACTERISTICS FOR US OLDER ADULTS. Innovation In Aging 2023, 7: 823-823. PMCID: PMC10739216, DOI: 10.1093/geroni/igad104.2654.Peer-Reviewed Original ResearchOlder adultsCare needsMore unmet needsDifferent care needsType of careAging Trends StudyMultimorbidity combinationsMultimorbidity patternsMusculoskeletal conditionsChronic conditionsNational HealthMedian numberUnmet needAssociated careMultimorbidityCareIADL domainsLatent classesAbstract Older adultsAdultsFurther investigationFour-class solutionHealthy classCaregiversSmall proportion
2022
SOCIAL SUPPORT AND STRAIN AS PREDICTORS OF MULTIMORBIDITY FOLLOWING A MARITAL TRANSITION
Denning E, Newsom J, Botoseneanu A, Allore H, Nagel C, Dorr D, Quiñones A. SOCIAL SUPPORT AND STRAIN AS PREDICTORS OF MULTIMORBIDITY FOLLOWING A MARITAL TRANSITION. Innovation In Aging 2022, 6: 567-567. PMCID: PMC9770881, DOI: 10.1093/geroni/igac059.2136.Peer-Reviewed Original ResearchMore chronic conditionsChronic conditionsPredictors of multimorbiditySocial supportAdults age 50Race/ethnicityAge 50Multimorbidity trajectoriesOlder adultsMarital transitionsHealth declineSocial strainStressful eventsRetirement StudyChildrenSpousal supportGrowth curve modelingPiecewise growth curve modelingHealthLtParticipantsMultimorbidityRACIAL-ETHNIC VARIATION IN MULTIMORBIDITY PATTERNS AND HEALTHCARE SERVICES AMONG OLDEST-OLD PATIENTS
Cho J, Rahimighazikalayeh G, Allore H. RACIAL-ETHNIC VARIATION IN MULTIMORBIDITY PATTERNS AND HEALTHCARE SERVICES AMONG OLDEST-OLD PATIENTS. Innovation In Aging 2022, 6: 795-795. PMCID: PMC9767161, DOI: 10.1093/geroni/igac059.2870.Peer-Reviewed Original ResearchMultiple chronic conditionsOldest-old patientsHealthcare service utilizationPatterns of multimorbidityClinic visitsEmergency departmentHispanic patientsService utilizationHealthcare systemAge-related risk factorsIntegrated healthcare systemRacial-ethnic variationsMetabolism syndromeWhite patientsBlack patientsMultimorbidity patternsChronic conditionsRisk factorsClinical dataPatientsCare managementAlzheimer's diseaseDiverse patientsRelated dementiaSignificant associationThe Contribution of Chronic Conditions to Hospitalization, Skilled Nursing Facility Admission, and Death: Variation by Race
Quiñones AR, McAvay GJ, Peak KD, Vander Wyk B, Allore HG. The Contribution of Chronic Conditions to Hospitalization, Skilled Nursing Facility Admission, and Death: Variation by Race. American Journal Of Epidemiology 2022, 191: 2014-2025. PMID: 35932162, PMCID: PMC10144669, DOI: 10.1093/aje/kwac143.Peer-Reviewed Original ResearchConceptsSkilled nursing facility admissionsNursing facility admissionsChronic conditionsFacility admissionMedicare beneficiariesCostly health care utilizationHealth care utilizationRacial differencesNon-Hispanic blacksWhite Medicare beneficiariesAverage attributable fractionHealth-related outcomesImportant health-related outcomesNon-Hispanic White older adultsWhite older adultsAging Trends StudyMultimorbidity burdenRenal morbidityOngoing careAttributable fractionNational HealthCardiovascular conditionsOlder adultsImportant markerHospitalization
2020
Individual Heterogeneity in the Probability of Hospitalization, Skilled Nursing Facility Admission, and Mortality
McAvay GJ, Vander Wyk B, Allore H. Individual Heterogeneity in the Probability of Hospitalization, Skilled Nursing Facility Admission, and Mortality. The Journals Of Gerontology Series A 2020, 76: 1668-1677. PMID: 33320184, PMCID: PMC8361334, DOI: 10.1093/gerona/glaa314.Peer-Reviewed Original ResearchConceptsSkilled nursing facility admissionsNursing facility admissionsChronic kidney diseaseHeart failureFacility admissionKidney diseaseChronic conditionsChronic obstructive pulmonary diseaseObstructive pulmonary diseaseIschemic heart diseaseHealth care utilizationProbability of hospitalizationPulmonary diseaseCare utilizationMortality outcomesPoor outcomeHeart diseaseNational HealthOdds ratioDisease combinationsLongitudinal cohortSociodemographic factorsMedicaid ServicesDiseaseAging Study
2016
Methodology to Estimate the Longitudinal Average Attributable Fraction of Guideline-recommended Medications for Death in Older Adults With Multiple Chronic Conditions
Allore HG, Zhan Y, Cohen AB, Tinetti ME, Trentalange M, McAvay G. Methodology to Estimate the Longitudinal Average Attributable Fraction of Guideline-recommended Medications for Death in Older Adults With Multiple Chronic Conditions. The Journals Of Gerontology Series A 2016, 71: 1113-1116. PMID: 26748093, PMCID: PMC4945884, DOI: 10.1093/gerona/glv223.Peer-Reviewed Original ResearchMeSH KeywordsAdrenergic beta-AntagonistsAgedAged, 80 and overCardiovascular DiseasesDrug PrescriptionsDrug Therapy, CombinationFemaleFollow-Up StudiesHumansMaleMedicareMultiple Chronic ConditionsPractice Guidelines as TopicRetrospective StudiesSurveys and QuestionnairesSurvival RateThiazidesTreatment OutcomeUnited StatesConceptsMultiple chronic conditionsAverage attributable fractionChronic conditionsAttributable fractionCardiovascular conditionsHeart failureMedicare Current Beneficiary Survey participantsRenin-angiotensin system blockersGuideline-recommended medicationsMore chronic conditionsAge-stratified modelsSystem blockersBeta blockersCardiovascular medicationsOral medicationsAtrial fibrillationMedication effectsMedicationsAge strataParticipant characteristicsOlder adultsSurvivalThiazidesBlockersAgeIndividualized Absolute Risk Calculations for Persons with Multiple Chronic Conditions: Embracing Heterogeneity, Causality, and Competing Events
Allore H, McAvay G, Fragoso C, Murphy TE. Individualized Absolute Risk Calculations for Persons with Multiple Chronic Conditions: Embracing Heterogeneity, Causality, and Competing Events. International Journal Of Statistics In Medical Research 2016, 5: 48-55. PMID: 27076862, PMCID: PMC4827855, DOI: 10.6000/1929-6029.2016.05.01.5.Peer-Reviewed Original ResearchMultiple chronic conditionsPatient-centered outcomesPatient reported outcomesAbsolute risk calculationRisk calculatorChronic conditionsMore chronic medical conditionsPopulation of patientsChronic medical conditionsComplex treatment decisionsTreatment effectsPatient characteristicsAbsolute riskReported outcomesTreatment decisionsMedical conditionsPropensity score methodsSpecific treatmentRisk calculationOutcomesCompeting EventsPatientsTreatmentRiskScore method
2015
Association between guideline recommended drugs and death in older adults with multiple chronic conditions: population based cohort study
Tinetti ME, McAvay G, Trentalange M, Cohen AB, Allore HG. Association between guideline recommended drugs and death in older adults with multiple chronic conditions: population based cohort study. The BMJ 2015, 351: h4984. PMID: 26432468, PMCID: PMC4591503, DOI: 10.1136/bmj.h4984.Peer-Reviewed Original ResearchConceptsSerotonin-norepinephrine reuptake inhibitorsMultiple chronic conditionsSelective serotonin reuptake inhibitorsAdjusted hazard ratioRisk of deathCalcium channel blockersChronic conditionsHazard ratioΒ-blockersCohort studyReuptake inhibitorsAtrial fibrillationOlder adultsChannel blockersCardiovascular drugsSSRIs/serotonin-norepinephrine reuptake inhibitorsRenin-angiotensin system blockersNorepinephrine reuptake inhibitorsSerotonin reuptake inhibitorsCommon combinationRAS blockersSystem blockersStudy drugHeart failureThromboembolic disease