1997
Hepatic and Gastrointestinal Oxygen and Lactate Metabolism during Low Cardiac Output in Lambs
Fahey J, Lister G, Sanfilippo D, Edelstone D. Hepatic and Gastrointestinal Oxygen and Lactate Metabolism during Low Cardiac Output in Lambs. Pediatric Research 1997, 41: 842-851. PMID: 9167197, DOI: 10.1203/00006450-199706000-00008.Peer-Reviewed Original ResearchConceptsHepatic lactate uptakeHepatic O2 deliveryCardiac outputO2 deliveryHepatic O2 consumptionLactate uptakeLactate accumulationLactic acidosisGI tractNet hepatic lactate uptakeLow cardiac outputGastrointestinal blood flowYoung lambsSystemic O2 deliveryLactate productionExtraction of lactateGreater percent decreaseNet lactate productionO2 consumptionConscious lambsHepatic dysfunctionLactate deliveryO2/minBlood flowAdult subjects
1993
Metabolic responses to hypoxia
LISTER G. Metabolic responses to hypoxia. Critical Care Medicine 1993, 21: s340. PMID: 8395993, DOI: 10.1097/00003246-199309001-00022.Peer-Reviewed Original Research
1992
Oxygen transport during anemic hypoxia in pigs: effects of digoxin on metabolism
Saltiel A, Sanfilippo DJ, Hendler R, Lister G. Oxygen transport during anemic hypoxia in pigs: effects of digoxin on metabolism. American Journal Of Physiology 1992, 263: h208-h217. PMID: 1636760, DOI: 10.1152/ajpheart.1992.263.1.h208.Peer-Reviewed Original ResearchConceptsTissue hypoxiaO2 extractionBlood flowHigh-output cardiac failureWhole-body O2 consumptionO2 deficitFemoral venous lactateNormal ventricular functionEffect of digoxinHindlimb blood flowRelease of catecholaminesWhole bodyO2 consumptionDigoxin groupCatecholamine responsesSerum catecholaminesVenous lactateCardiac failureVentricular functionArterial lactateSevere anemiaCardiac outputCatecholamine secretionAnemic hypoxiaO2 demand
1989
Response to Low Cardiac Output: Developmental Differences in Metabolism during Oxygen Deficit and Recovery in Lambs
Fahey J, Lister G. Response to Low Cardiac Output: Developmental Differences in Metabolism during Oxygen Deficit and Recovery in Lambs. Pediatric Research 1989, 26: 180-187. PMID: 2587117, DOI: 10.1203/00006450-198909000-00003.Peer-Reviewed Original ResearchConceptsLow cardiac outputCardiac outputAge groupsPulmonary artery blood pressureO2 deficitOld lambsO2 consumptionArtery blood pressureArterial lactate concentrationMin of recoveryRespective study periodsVenous HbBlood pressureFoley catheterRight atriumO2 saturationLactate concentrationStudy periodYoung lambsAge 2Potential mechanismsYoung animalsHypoxic stressComparable deficitsMetabolic demandsEffect of hemoglobin concentration on critical cardiac output and oxygen transport
Heusser F, Fahey JT, Lister G. Effect of hemoglobin concentration on critical cardiac output and oxygen transport. American Journal Of Physiology 1989, 256: h527-h532. PMID: 2916686, DOI: 10.1152/ajpheart.1989.256.2.h527.Peer-Reviewed Original ResearchConceptsSystemic O2 transportPeripheral O2 extractionCardiac outputO2 extractionFractional O2 extractionHemoglobin concentrationArterial blood lactate concentrationBase-line cardiac outputBalloon-tipped catheterPacked red cellsBlood lactate concentrationO2 transportPhysiological anaemiaExchange transfusionAcute reductionRight atriumVenous PO2Relative anemiaLactate concentrationOld lambsRed cellsAnemiaProgressive decreaseBase lineO2 consumption
1988
Hypoxanthine and lactate concentrations in lambs during hypoxic and stagnant hypoxia
Moss M, Kurzner S, Razlog Y, Lister G. Hypoxanthine and lactate concentrations in lambs during hypoxic and stagnant hypoxia. American Journal Of Physiology 1988, 255: h53-h59. PMID: 3394825, DOI: 10.1152/ajpheart.1988.255.1.h53.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsAnimalsCardiac OutputHypoxanthineHypoxanthinesHypoxiaLactatesLactic AcidOxygen ConsumptionSheepConceptsLow cardiac outputCardiac outputForms of hypoxiaPlasma hypoxanthineTissue hypoxiaO2 deficitHypoxanthine concentrationsPlasma hypoxanthine concentrationBlood lactate concentrationO2 deprivationRate of eliminationHypoxic hypoxiaKetamine sedationStagnant hypoxiaReliable markerHypoxemiaLactate concentrationHypoxiaComparable reductionDeficitsMarkersHypoxanthineO2 transportDeprivationLambs
1987
Oxygen Transport and Metabolism in the Conscious Lamb: The Effects of Hypoxemia
Moss M, Moreau G, Lister G. Oxygen Transport and Metabolism in the Conscious Lamb: The Effects of Hypoxemia. Pediatric Research 1987, 22: 177-183. PMID: 3658543, DOI: 10.1203/00006450-198708000-00016.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAnimalsAnimals, NewbornBiological Transport, ActiveHypoxiaLactatesLactic AcidOxygenOxygen ConsumptionSheepConceptsSystemic O2 transportRespiratory exchange ratioBase deficitLactate concentrationArterial blood lactate concentrationAge groupsO2 consumptionExchange ratioEffects of hypoxemiaBlood lactate concentrationO2 transportAge related differencesConscious lambsSevere hypoxemiaAlveolar hypoxiaTissue hypoxiaAccumulation of lactateBaseline valuesBlood lactateHypoxemiaNewborn lambsMetabolic consequencesMetabolic responseHypoxiaRelated differencesPostnatal changes in critical cardiac output and oxygen transport in conscious lambs
Fahey J, Lister G. Postnatal changes in critical cardiac output and oxygen transport in conscious lambs. American Journal Of Physiology 1987, 253: h100-h106. PMID: 3605355, DOI: 10.1152/ajpheart.1987.253.1.h100.Peer-Reviewed Original ResearchMeSH KeywordsAgingAnimalsAnimals, NewbornBiological TransportCardiac OutputConsciousnessOxygen ConsumptionSheepConceptsSystemic oxygen transportCardiac outputFractional oxygen extractionOxygen extractionOld lambsBalloon-tipped catheterSystemic oxygen deliveryBase-line valuesWk of ageIncremental inflationUnsedated lambsConscious lambsBlood pressureArterial lactateRight atriumAcute decreaseLactic acid accumulationOxygen deliveryPostnatal changesOxygen transportOxygen consumption
1984
Effects of alterations of oxygen transport on the neonate.
Lister G, Moreau G, Moss M, Talner N. Effects of alterations of oxygen transport on the neonate. Seminars In Perinatology 1984, 8: 192-204. PMID: 6204388.Peer-Reviewed Original ResearchFunctional assessment of the pulmonary microcirculation during postnatal development.
Lister G, Kopf G, Pitt B. Functional assessment of the pulmonary microcirculation during postnatal development. Neonatology 1984, 4: 85-99. PMID: 6091021.Peer-Reviewed Original Research
1983
Cardiopulmonary Interactions in the Infant with Congenital Cardiac Disease
Lister G, Pitt B. Cardiopulmonary Interactions in the Infant with Congenital Cardiac Disease. Clinics In Chest Medicine 1983, 4: 219-232. PMID: 6342921, DOI: 10.1016/s0272-5231(21)00200-8.Peer-Reviewed Original Research
1982
Physiologic Effects of Increasing Hemoglobin Concentration in Left-to-Right Shunting in Infants with Ventricular Septal Defects
Lister G, Hellenbrand W, Kleinman C, Talner N. Physiologic Effects of Increasing Hemoglobin Concentration in Left-to-Right Shunting in Infants with Ventricular Septal Defects. New England Journal Of Medicine 1982, 306: 502-506. PMID: 7057857, DOI: 10.1056/nejm198203043060902.Peer-Reviewed Original ResearchConceptsPulmonary vascular resistanceVentricular septal defectRight shuntVascular resistanceHemoglobin concentrationSeptal defectBlood flowLarge ventricular septal defectLeft ventricular stroke workSystemic blood flowVentricular stroke workPulmonary blood flowSystemic oxygen transportIsovolemic exchange transfusionHigher hemoglobin concentrationRight shuntingExchange transfusionStroke workClinical signsAcute effectsPhysiologic effectsSystemic circulationPostnatal declineIsolated circulationNormal fall
1981
Effect of physical training on exercise performance of children following surgical repair of congenital heart disease.
Goldberg B, Fripp R, Lister G, Loke J, Nicholas J, Talner N. Effect of physical training on exercise performance of children following surgical repair of congenital heart disease. Pediatrics 1981, 68: 691-9. PMID: 7312473, DOI: 10.1542/peds.68.5.691.Peer-Reviewed Original ResearchConceptsMaximum work capacitySurgical repairExercise performanceMaximum oxygen consumptionWork capacityPhysical trainingHeart rateOxygen consumptionHome exercise programVentricular septal defectCongenital heart diseaseWork loadExercise testingExercise programSeptal defectHeart diseaseBicycle ergometerPatientsLevel of activitySignificant differencesOne-thirdTwo-thirdsTraining sessionsRepairOne-halfThe Pathophysiology of disorders of oxygen transport in the infant
Talner N, Lister G. The Pathophysiology of disorders of oxygen transport in the infant. Current Problems In Pediatric And Adolescent Health Care 1981, 11: 7-50. PMID: 7226876, DOI: 10.1016/0045-9380(81)90037-2.Peer-Reviewed Original ResearchConceptsPathophysiology of disordersLower airwaysSurgical treatmentClinical presentationPathophysiologic mechanismsPulmonary circulationHematologic systemLung parenchymaOxygen deliveryPathologic processesControl of respirationOrgan systemsOxygen uptakeLungInfantsTissueDisordersSupply of oxygenHeartAdaptive responseCirculationAirwayPathophysiologyLesionsOxygen transport