1985
A simple method for reducing cardiac output in the conscious lamb
Fahey J, Lister G. A simple method for reducing cardiac output in the conscious lamb. American Journal Of Physiology 1985, 249: h188-h192. PMID: 4014483, DOI: 10.1152/ajpheart.1985.249.1.h188.Peer-Reviewed Original ResearchConceptsCardiac outputBalloon inflationBalloon-tipped catheterSystemic venous returnArterial lactate concentrationSystemic blood flowResting cardiac outputSmall neck incisionStable cardiac outputDays of ageUnsedated lambsConscious lambsBlood pressureVenous returnBalloon deflationNeck incisionRight atriumJugular veinMetabolic variablesO2 extractionBlood flowAnimal survivalLactate concentrationO2 consumptionLambs
1982
Physiologic Effects of Increasing Hemoglobin Concentration in Left-to-Right Shunting in Infants with Ventricular Septal Defects
Lister G, Hellenbrand W, Kleinman C, Talner N. Physiologic Effects of Increasing Hemoglobin Concentration in Left-to-Right Shunting in Infants with Ventricular Septal Defects. New England Journal Of Medicine 1982, 306: 502-506. PMID: 7057857, DOI: 10.1056/nejm198203043060902.Peer-Reviewed Original ResearchConceptsPulmonary vascular resistanceVentricular septal defectRight shuntVascular resistanceHemoglobin concentrationSeptal defectBlood flowLarge ventricular septal defectLeft ventricular stroke workSystemic blood flowVentricular stroke workPulmonary blood flowSystemic oxygen transportIsovolemic exchange transfusionHigher hemoglobin concentrationRight shuntingExchange transfusionStroke workClinical signsAcute effectsPhysiologic effectsSystemic circulationPostnatal declineIsolated circulationNormal fall