1982
Physiologic Effects of Increasing Hemoglobin Concentration in Left-to-Right Shunting in Infants with Ventricular Septal Defects
Lister G, Hellenbrand W, Kleinman C, Talner N. Physiologic Effects of Increasing Hemoglobin Concentration in Left-to-Right Shunting in Infants with Ventricular Septal Defects. New England Journal Of Medicine 1982, 306: 502-506. PMID: 7057857, DOI: 10.1056/nejm198203043060902.Peer-Reviewed Original ResearchConceptsPulmonary vascular resistanceVentricular septal defectRight shuntVascular resistanceHemoglobin concentrationSeptal defectBlood flowLarge ventricular septal defectLeft ventricular stroke workSystemic blood flowVentricular stroke workPulmonary blood flowSystemic oxygen transportIsovolemic exchange transfusionHigher hemoglobin concentrationRight shuntingExchange transfusionStroke workClinical signsAcute effectsPhysiologic effectsSystemic circulationPostnatal declineIsolated circulationNormal fall
1981
Effect of physical training on exercise performance of children following surgical repair of congenital heart disease.
Goldberg B, Fripp R, Lister G, Loke J, Nicholas J, Talner N. Effect of physical training on exercise performance of children following surgical repair of congenital heart disease. Pediatrics 1981, 68: 691-9. PMID: 7312473, DOI: 10.1542/peds.68.5.691.Peer-Reviewed Original ResearchConceptsMaximum work capacitySurgical repairExercise performanceMaximum oxygen consumptionWork capacityPhysical trainingHeart rateOxygen consumptionHome exercise programVentricular septal defectCongenital heart diseaseWork loadExercise testingExercise programSeptal defectHeart diseaseBicycle ergometerPatientsLevel of activitySignificant differencesOne-thirdTwo-thirdsTraining sessionsRepairOne-half