2005
Sexual Risk Behavior Among Injection Drug Users Before Widespread Availability of Highly Active Antiretroviral Therapy
Rusch M, Farzadegan H, Tarwater P, Safaeian M, Vlahov D, Strathdee S. Sexual Risk Behavior Among Injection Drug Users Before Widespread Availability of Highly Active Antiretroviral Therapy. AIDS And Behavior 2005, 9: 289-299. PMID: 16133905, DOI: 10.1007/s10461-005-9003-4.Peer-Reviewed Original ResearchConceptsInjection drug usersCondom useAntiretroviral therapyHIV testingDrug usersEligible injection drug usersRisk behaviorsActive antiretroviral therapyInconsistent condom useSexual risk behaviorsIDU cohortHIV transmissionRetrospective analysisLower riskStudy exposureSexual riskLong-term studiesTherapySignificant changesCounselingRiskExposureLogistic modelWidespread availabilityCohortSuicidal ideation among African-American non-injection drug users.
Havens J, Ompad D, Latkin C, Fuller C, Arria A, Vlahov D, Strathdee S. Suicidal ideation among African-American non-injection drug users. Ethnicity & Disease 2005, 15: 110-5. PMID: 15720057.Peer-Reviewed Original ResearchConceptsSuicidal ideationDrug usersDrug dependenceNon-injection drug usersCommunity-based cohortInterview-administered questionnaireMultiple logistic regressionDrug use historyUse of heroinAfrican American drug usersMedian agePsychiatric comorbidityDepressive symptomsMore drugsSuicidal thoughtsLogistic regressionIdeationAfrican AmericansUse historyParticipantsComorbiditiesCohortSymptomsYearsHeroin
2003
Longitudinal Patterns of Drug Injection Behavior in the ALIVE Study Cohort,1988–2000: Description and Determinants
Galai N, Safaeian M, Vlahov D, Bolotin A, Celentano D. Longitudinal Patterns of Drug Injection Behavior in the ALIVE Study Cohort,1988–2000: Description and Determinants. American Journal Of Epidemiology 2003, 158: 695-704. PMID: 14507606, DOI: 10.1093/aje/kwg209.Peer-Reviewed Original ResearchConceptsInjection drug usersDrug injection behaviorDrug usersIntravenous Experience (ALIVE) studyDrug treatment programsHistory of incarcerationLogistic regression modelsALIVE studySemiannual visitsMultinomial logistic regression modelsBaseline factorsChronic diseasesDrug injectionRecent overdoseCessation attemptsDrug use transitionsDrug injectorsCommunity outreach effortsLongitudinal patternsHigh mortalityEarly determinantsYounger ageTreatment programInjection behaviorStudy periodGenetic influence of CXCR6 chemokine receptor alleles on PCP-mediated AIDS progression among African Americans
Duggal P, An P, Beaty T, Strathdee S, Farzadegan H, Markham R, Johnson L, O'Brien S, Vlahov D, Winkler C. Genetic influence of CXCR6 chemokine receptor alleles on PCP-mediated AIDS progression among African Americans. Genes & Immunity 2003, 4: 245-250. PMID: 12761559, DOI: 10.1038/sj.gene.6363950.Peer-Reviewed Original ResearchConceptsPneumocystis carinii pneumoniaLate-stage HIV-1 infectionAfrican AmericansHIV-1 infectionMedian survival timeSIV infectionCarinii pneumoniaChemokine receptorsAIDS progressionPrimary coreceptorSurvival timeK polymorphismInitial infectionCXCR6Receptor allelesInfectionProgressionSingle nucleotide polymorphismsDeathK genotypesAIDSCoreceptorNucleotide polymorphismsGenetic influencesAllele frequenciesThe Role of Medicaid HMO Enrollment in the Longitudinal Utilization of Medical Care Services in a Cohort of Injecting Drug users in Baltimore, Maryland
Juday T, Wu A, Celentano D, Rick K, Wang M, Vlahov D. The Role of Medicaid HMO Enrollment in the Longitudinal Utilization of Medical Care Services in a Cohort of Injecting Drug users in Baltimore, Maryland. Substance Abuse 2003, 24: 27-41. PMID: 12652093, DOI: 10.1080/08897070309511531.Peer-Reviewed Original ResearchConceptsAmbulatory care visitsCare visitsInpatient admissionsHMO enrollmentDrug usersMedicaid HMO enrolleesMore inpatient admissionsInjecting Drug UsersMedical care utilizationNatural history studiesIntravenous Experience (ALIVE) studyMedical care servicesCommunity-based sampleLongitudinal utilizationER visitsHIV infectionCare utilizationMedicaid beneficiariesHMO enrolleesCare servicesIDUsInappropriate utilizationUtilization differencesMedicaidMedicaid HMOsFactors Associated With Human Herpesvirus Type 8 Infection in an Injecting Drug User Cohort
Bernstein K, Jacobson L, Jenkins F, Vlahov D, Armenian H. Factors Associated With Human Herpesvirus Type 8 Infection in an Injecting Drug User Cohort. Sexually Transmitted Diseases 2003, 30: 199-204. PMID: 12616135, DOI: 10.1097/00007435-200303000-00004.Peer-Reviewed Original ResearchConceptsHHV-8 seroprevalenceRisk factorsHHV-8Human herpesvirus type 8 infectionLarger body mass indexHuman herpesvirus type 8Drug user cohortHHV-8 seropositivityInjection drug useBody mass indexMultivariate logistic regressionCross-sectional studyDrug user populationGenital wartsMass indexGeneral populationDrug useSeroprevalenceIndirect immunofluorescenceLogistic regressionIDUsInfectionType 8User cohortSexual behaviorFeasibility of referring drug users from a needle exchange program into an addiction treatment program: Experience with a mobile treatment van and LAAM maintenance
Kuo I, Brady J, Butler C, Schwartz R, Brooner R, Vlahov D, Strathdee S. Feasibility of referring drug users from a needle exchange program into an addiction treatment program: Experience with a mobile treatment van and LAAM maintenance. Journal Of Substance Use And Addiction Treatment 2003, 24: 67-74. PMID: 12646332, DOI: 10.1016/s0740-5472(02)00343-4.Peer-Reviewed Original ResearchMeSH KeywordsAdultBaltimoreCocaine-Related DisordersFeasibility StudiesFemaleHeroin DependenceHumansMaleMethadyl AcetateMobile Health UnitsNarcoticsNeedle-Exchange ProgramsReferral and ConsultationSeverity of Illness IndexSubstance Abuse Treatment CentersSubstance-Related DisordersTime FactorsTreatment OutcomeConceptsTreatment programLevomethadyl acetate hydrochlorideFirst-line treatmentEarly treatment responseNeedle exchange programsCocaine-positive urine testsDrug treatment programsAddiction treatment programsLAAM maintenanceAgonist therapyLine treatmentOpioid dependenceUrine testsTreatment responseDrug usersNEP attendersHeroin addictionProgram attendersAlcohol useSubscale scoresProgram entrySignificant reductionAttendersLAAM
2002
HEALTH SERVICES UTILIZATION BY INJECTION DRUG USERS PARTICIPATING IN A NEEDLE EXCHANGE PROGRAM
Riley E, Wu A, Junge B, Marx M, Strathdee S, Vlahov D. HEALTH SERVICES UTILIZATION BY INJECTION DRUG USERS PARTICIPATING IN A NEEDLE EXCHANGE PROGRAM. The American Journal Of Drug And Alcohol Abuse 2002, 28: 497-511. PMID: 12211362, DOI: 10.1081/ada-120006738.Peer-Reviewed Original ResearchConceptsNeedle exchange programsDrug treatment utilizationDrug treatmentNEP visitsPrimary careHealth insuranceTreatment utilizationHealth careDrug usersHealth service utilization dataPrimary care utilizationHealth service utilizationAfrican American raceInjection drug usersBaltimore Needle Exchange ProgramHealth Insurance ServicePrimary health careService utilization dataHealth care systemNEP sitesMedian ageCare utilizationOdds ratioService utilizationStudy staffDRUG USER TREATMENT REFERRALS AND ENTRY AMONG PARTICIPANTS OF A NEEDLE EXCHANGE PROGRAM
Riley E, Safaeian M, Strathdee S, Brooner R, Beilenson P, Vlahov D. DRUG USER TREATMENT REFERRALS AND ENTRY AMONG PARTICIPANTS OF A NEEDLE EXCHANGE PROGRAM. Substance Use & Misuse 2002, 37: 1869-1886. PMID: 12511056, DOI: 10.1081/ja-120014088.Peer-Reviewed Original ResearchConceptsNEP participantsNeedle exchange programsTreatment referralMethadone treatmentMultiple logistic regression modelUse of speedballsDrug user treatmentNeedle exchange program participantsLogistic regression modelsMedian ageMethadone maintenanceOdds ratioFemale genderFirst injectionDrug useTreatment entryReferral
2001
Dynamics of SEN Virus Infection among Injection Drug Users
Wilson L, Umemura T, Astemborski J, Ray S, Alter H, Strathdee S, Vlahov D, Thomas D. Dynamics of SEN Virus Infection among Injection Drug Users. The Journal Of Infectious Diseases 2001, 184: 1315-1319. PMID: 11679921, DOI: 10.1086/324001.Peer-Reviewed Original ResearchConceptsInjection drug usersSEN virusDrug usersSEN virus infectionSENV-H DNASENV-H infectionPosttransfusion hepatitisSENV infectionViral clearancePolymerase chain reactionViral persistenceClinical significanceVirus infectionInfectionSerum samplesChain reactionReinfectionVirusDNA virusesHepatitisClearanceAccess to medical care and service utilization among injection drug users with HIV/AIDS
Knowlton A, Hoover D, Chung S, Celentano D, Vlahov D, Latkin C. Access to medical care and service utilization among injection drug users with HIV/AIDS. Drug And Alcohol Dependence 2001, 64: 55-62. PMID: 11470341, DOI: 10.1016/s0376-8716(00)00228-3.Peer-Reviewed Original ResearchConceptsCase managementService utilizationDrug treatmentCurrent drug injectorsOutpatient service usePhysical functioning limitationsEmergency room useInjection drug usersCurrent drug useDaily alcohol useHIV/AIDSSubstance abuse treatmentHIV careAIDS diagnosisOutpatient careFunctioning limitationsDrug injectorsOutpatient servicesService useDrug usersDrug useMedical careAbuse treatmentHospital servicesAlcohol useHighly Active Antiretroviral Therapy Associated with Improved Anemia Among HIV-Infected Women
Semba R, Shah N, Klein R, Mayer K, Schuman P, Gardner L, Vlahov D. Highly Active Antiretroviral Therapy Associated with Improved Anemia Among HIV-Infected Women. AIDS Patient Care And STDs 2001, 15: 473-480. PMID: 11587633, DOI: 10.1089/108729101753145466.Peer-Reviewed Original ResearchConceptsPrevalence of anemiaAntiretroviral therapyHuman immunodeficiency virus (HIV) infectionActive antiretroviral therapyCombination antiretroviral therapyImmunodeficiency virus infectionHIV-positive womenYears of treatmentIncrease of hemoglobinImproved anemiaMulticenter cohortVirus infectionHAARTAnemiaHIVWomenTherapyLinear regression modelsPrevalenceTreatmentBaselineHemoglobinRegression modelsSignificant changesMonotherapyUse of Audio Computer-assisted Self-Interviews to Assess Tuberculosis-related Risk Behaviors
RILEY E, CHAISSON R, ROBNETT T, VERTEFEUILLE J, STRATHDEE S, VLAHOV D. Use of Audio Computer-assisted Self-Interviews to Assess Tuberculosis-related Risk Behaviors. American Journal Of Respiratory And Critical Care Medicine 2001, 164: 82-85. PMID: 11435243, DOI: 10.1164/ajrccm.164.1.2101091.Peer-Reviewed Original ResearchConceptsInterviewer-assisted questionnaireComputer-assisted questionnaireHIV infectionRisk factorsOdds ratioHuman immunodeficiency virus risk factorsSelf-reported tuberculosisMultiple logistic regressionRisk behavior dataFinal multivariate modelSmoking equipmentNeedle exchange programsNeedle exchange program participantsHigh-risk behaviorsUnderwent interviewsHIV serostatusAlcohol intakeCigarette smokingDrug useHealth statusRisk behaviorsTuberculosisSmoking marijuanaLogistic regressionMultivariate modelNeedle-exchange participation, effectiveness, and policy: Syringe relay, gender, and the paradox of public health
Valente T, Foreman R, Junge B, Vlahov D. Needle-exchange participation, effectiveness, and policy: Syringe relay, gender, and the paradox of public health. Journal Of Urban Health 2001, 78: 340-349. PMID: 11419584, PMCID: PMC3456352, DOI: 10.1093/jurban/78.2.340.Peer-Reviewed Original ResearchMeSH KeywordsAdultBaltimoreCommerceCommunity Health PlanningCounselingFemaleHealth BehaviorHealth EducationHIV InfectionsHumansInterpersonal RelationsMaleMiddle AgedNeedle-Exchange ProgramsOrganizational ObjectivesProgram EvaluationSocial SupportSubstance Abuse, IntravenousSurveys and QuestionnairesSyringesUrban HealthConceptsNeedle exchange programsNEP useIntravenous drug usersBaltimore Needle Exchange ProgramPublic health goalsHIV seroconversionHIV protectionDrug usersHealth goalsVirus transmission rateHigh usersDuration of contactPublic healthEducation effortsCirculation timeMost studiesRelay activityExclusive useParticipantsSeroconversionHIVVisitsWomenSex Differences in Risk Factors for HIV Seroconversion Among Injection Drug Users: A 10-Year Perspective
Strathdee S, Galai N, Safaiean M, Celentano D, Vlahov D, Johnson L, Nelson K. Sex Differences in Risk Factors for HIV Seroconversion Among Injection Drug Users: A 10-Year Perspective. JAMA Internal Medicine 2001, 161: 1281-1288. PMID: 11371255, DOI: 10.1001/archinte.161.10.1281.Peer-Reviewed Original ResearchConceptsInjection drug usersIncidence of HIVHIV seroconversionRisk factorsProspective studyDrug usersHigh-risk heterosexual activityHuman immunodeficiency virus interventionsHIV-negative injection drug usersHuman immunodeficiency virus (HIV) infectionFemale injection drug usersImmunodeficiency virus infectionInjection drug useDrug-related risksHomosexual activityTime-dependent covariatesHIV testMedian agePerson yearsDaily injectionsNeedle sharingCocaine injectionHIV riskVirus infectionSeroconversionImprovement of Anemia Among HIV-Infected Injection Drug Users Receiving Highly Active Antiretroviral Therapy
Semba R, Shah N, Vlahov D. Improvement of Anemia Among HIV-Infected Injection Drug Users Receiving Highly Active Antiretroviral Therapy. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2001, 26: 315-319. PMID: 11317071, DOI: 10.1097/00126334-200104010-00003.Peer-Reviewed Original ResearchMeSH KeywordsAdultAIDS-Related Opportunistic InfectionsAnemiaAnti-HIV AgentsAntiretroviral Therapy, Highly ActiveBaltimoreBody Mass IndexCD4 Lymphocyte CountChronic DiseaseFemaleHemoglobinsHIV InfectionsHIV-1HumansLongitudinal StudiesMaleMultivariate AnalysisPrevalenceSex FactorsSubstance Abuse, IntravenousViral LoadConceptsInjection drug usersPlasma HIV loadActive antiretroviral therapyAntiretroviral therapyHIV loadOpportunistic infectionsCopies/Mean decreaseDrug usersHIV-positive injection drug usersPotent antiretroviral therapyImprovement of anemiaBody mass indexIncrease of hemoglobinAntiretroviral medicationsHIV infectionMass indexControl subjectsOverall prevalenceChronic diseasesAnemiaNutritional statusMean increaseMultivariate analysisHAARTFactors Associated with Adolescent Initiation of Injection Drug Use
Fuller C, Vlahov D, Arria A, Ompad D, Garfein R, Strathdee S. Factors Associated with Adolescent Initiation of Injection Drug Use. Public Health Reports 2001, 116: 136-145. PMID: 11889281, PMCID: PMC1913680, DOI: 10.1093/phr/116.s1.136.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdolescent BehaviorAdultAge FactorsBaltimoreBlack or African AmericanCommunity-Institutional RelationsFemaleHealth BehaviorHepatitis CHIV InfectionsHumansLogistic ModelsMalePrimary PreventionProspective StudiesRisk AssessmentRisk-TakingSexual BehaviorSubstance Abuse, IntravenousConceptsInjection drug useDrug useMedian ageInitiation of injectionCrack smokingNon-injection drug useAdolescent initiationHigh-risk groupYears of ageIllicit drug useAfrican AmericansDrug use practicesStudy enrollmentPrevents onsetEarly prevention effortsDrug usersMultivariate analysisCocaine useCondom useSmoking marijuanaLogistic regressionYoung drug usersPrevention effortsYoung adulthoodSmoking
2000
Trends in crime and the introduction of a needle exchange program.
Marx M, Crape B, Brookmeyer R, Junge B, Latkin C, Vlahov D, Strathdee S. Trends in crime and the introduction of a needle exchange program. American Journal Of Public Health 2000, 90: 1933-6. PMID: 11111271, PMCID: PMC1446444, DOI: 10.2105/ajph.90.12.1933.Peer-Reviewed Original ResearchThe prevalence of homelessness among injection drug users with and without HIV infection
Song J, Safaeian M, Strathdee S, Vlahov D, Celentano D. The prevalence of homelessness among injection drug users with and without HIV infection. Journal Of Urban Health 2000, 77: 678-687. PMID: 11194310, PMCID: PMC3456762, DOI: 10.1007/bf02344031.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusInjection drug usersInjection drug useIndependent predictorsDrug usersDrug useActive injection drug useLongitudinal cohort studyCross-sectional studyHIV/AIDSCross-sectional investigationHIV seroconversionCohort studyHIV seroprevalenceHIV infectionPrevalence of homelessnessImmunodeficiency virusMale sexLogistic regressionPrevalenceParticipantsMore experiencePredictorsSeroconversionSerostatusCorrelates of enrollment in methadone maintenance treatment programs differ by HIV-serostatus
Shah N, Celentano D, Vlahov D, Stambolis V, Johnson L, Nelson K, Strathdee S. Correlates of enrollment in methadone maintenance treatment programs differ by HIV-serostatus. AIDS 2000, 14: 2035-2043. PMID: 10997409, DOI: 10.1097/00002030-200009080-00020.Peer-Reviewed Original ResearchMeSH KeywordsAdultBaltimoreCohort StudiesFemaleHealth Services AccessibilityHIV AntibodiesHIV InfectionsHIV SeronegativityHIV SeropositivityHumansMaleMethadoneMiddle AgedNeedle-Exchange ProgramsProspective StudiesRisk-TakingSocioeconomic FactorsSubstance Abuse Treatment CentersSubstance Abuse, IntravenousConceptsMethadone maintenance treatment programInjection drug usersMaintenance treatment programNeedle exchange programsHIV serostatusHIV-seronegative injection drug usersSeronegative injection drug usersHIV-negative injection drug usersTreatment programHIV-seropositive participantsHealth care providersTreatment slotsNeedle exchange program participantsAfrican AmericansHIV testProspective cohortCare providersDrug usersProgram attendanceOlder ageCertain subgroupsVulnerable populationsSimilar proportionsBehavioral factorsEnrollment