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Emanuela Bruscia, PhD

Associate Professor of Pediatrics (Respiratory)
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Contact Info

Pediatric Pulmonology, Allergy, Immunology & Sleep Medicine

PO Box 208064

New Haven, CT 06520-8064

United States

About

Titles

Associate Professor of Pediatrics (Respiratory)

Biography

Dr. Bruscia received her Ph.D. in Biochemistry and Molecular Genetics from the University of Tor Vergata in Rome (Italy) in 2002. Since she was an undergraduate, her research has been dedicated to Cystic Fibrosis. During her undergraduate studies, she began working in the exciting field of gene therapy. She spent two years in the laboratory of Dr. Dieter Gruenert at the University of Vermont (Burlington, VT), where she worked on non-viral gene therapy strategies. She started her postdoctoral training in the laboratory of Dr. Diane Krause at Yale School of Medicine in 2002. Here, she explored the use of bone marrow-derived cells as a vehicle for gene therapy in the airway and intestinal epithelia in murine models for CF. In 2005, Dr. Bruscia was appointed as an Associate Research Scientist in the Department of Pediatrics at Yale School of Medicine and in 2010 promoted as an Assistant Professor in the same department. In 2016, she was promoted to Associate Professor. In the past ten years, her research interest has focused on the role of CFTR in the immune system, particularly in macrophages. The current focus of her lab is to explore emerging therapeutic strategies able to target several aspects of CF lung disease, while still proceeding with studies focused on understanding how the lack of CFTR is impairing macrophage function.

Appointments

Education & Training

PhD
Tor Vergata University in Rome (2002)

Research

Overview

Medical Subject Headings (MeSH)

Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Lung; Macrophages; Pediatrics; Respiration Disorders

Research at a Glance

Yale Co-Authors

Frequent collaborators of Emanuela Bruscia's published research.

Publications

2024

2023

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Contacts

Mailing Address

Pediatric Pulmonology, Allergy, Immunology & Sleep Medicine

PO Box 208064

New Haven, CT 06520-8064

United States