Publications

2023

Radiologically isolated syndrome.Lebrun-Frenay C, Kantarci O, Siva A, Azevedo CJ, Makhani N, Pelletier D, Okuda DT. Lancet Neurol. 2023 Nov; 2023 Oct 12. PMID: 37839432.
Interim guidelines for the assessment and treatment of pain in children with multiple sclerosis.Stratton C, Vassilopoulos A, Brenton JN, Potter K, Vargas W, Rumm H, Bartels A, Bailey M, Odonkor C, Stoll S, Zempsky EWT, Yeh EA, Makhani N. Front Neurosci. 2023; 2023 Sep 14. PMID: 37781253.
The radiologically isolated syndrome: revised diagnostic criteria.Lebrun-Frénay C, Okuda DT, Siva A, Landes-Chateau C, Azevedo CJ, Mondot L, Carra-Dallière C, Zephir H, Louapre C, Durand-Dubief F, Le Page E, Bensa C, Ruet A, Ciron J, Laplaud DA, Casez O, Mathey G, de Seze J, Zeydan B, Makhani N, Tutuncu M, Levraut M, Cohen M, Thouvenot E, Pelletier D, Kantarci OH. Brain. 2023 Aug 1. PMID: 36864688.
Radiologically Isolated Syndrome and the Multiple Sclerosis Prodrome in Pediatrics: Early Features of the Spectrum of Demyelination.Bower A, Makhani N. Semin Pediatr Neurol. 2023 Jul; 2023 May 12. PMID: 37451751.
MOGAD patient autoantibodies induce complement, phagocytosis, and cellular cytotoxicity.Yandamuri SS, Filipek B, Obaid AH, Lele N, Thurman JM, Makhani N, Nowak RJ, Guo Y, Lucchinetti CF, Flanagan EP, Longbrake EE, O'Connor KC. JCI Insight. 2023 Jun 8; 2023 Jun 8. PMID: 37097758.
Challenges in the Clinical Recognition of Acute Flaccid Myelitis and its Implications.Hayes LH, Hopkins SE, Liu S, Pardo CA, Garcia-Dominguez MA, Oleszek J, Yea C, Ciftci-Kavaklioglu B, Yeh EA, Dean J, Sadowsky CL, Desai J, Wiegand S, Farias-Moeller R, Nash K, Thakur KT, Vargas WS, Hong-Routson SJ, Yeshokumar A, Zhou MS, Makhani N, Wilson-Murphy M, Bove R, Zhang B, Benson LA. J Pediatr. 2023 Feb; 2022 Sep 15. PMID: 36115622.

2022

From the prodromal stage of multiple sclerosis to disease prevention.Marrie RA, Allegretta M, Barcellos LF, Bebo B, Calabresi PA, Correale J, Davis B, De Jager PL, Gasperi C, Greenbaum C, Helme A, Hemmer B, Kanellis P, Kostich W, Landsman D, Lebrun-Frenay C, Makhani N, Munger KL, Okuda DT, Ontaneda D, Postuma RB, Quandt JA, Roman S, Saidha S, Sormani MP, Strum J, Valentine P, Walton C, Zackowski KM, Zhao Y, Tremlett H. Nat Rev Neurol. 2022 Sep; 2022 Jul 15. PMID: 35840705.
Confirming a Historical Diagnosis of Multiple Sclerosis: Challenges and Recommendations.Solomon AJ, Arrambide G, Brownlee W, Cross AH, Gaitan MI, Lublin FD, Makhani N, Mowry EM, Reich DS, Rovira À, Weinshenker BG, Cohen JA. Neurol Clin Pract. 2022 Jun. PMID: 35747540.

2021

The Multiple Sclerosis Prodrome: Evidence to Action.Tremlett H, Munger KL, Makhani N. Front Neurol. 2021; 2022 Jan 31. PMID: 35173664.
Risk Factors and Time to Clinical Symptoms of Multiple Sclerosis Among Patients With Radiologically Isolated Syndrome.Lebrun-Frénay C, Rollot F, Mondot L, Zephir H, Louapre C, Le Page E, Durand-Dubief F, Labauge P, Bensa C, Thouvenot E, Laplaud D, de Seze J, Ciron J, Bourre B, Cabre P, Casez O, Ruet A, Mathey G, Berger E, Moreau T, Al Khedr A, Derache N, Clavelou P, Guennoc AM, Créange A, Neau JP, Tourbah A, Camdessanché JP, Maarouf A, Callier C, Vermersch P, Kantarci O, Siva A, Azevedo C, Makhani N, Cohen M, Pelletier D, Okuda D, Vukusic S. JAMA Netw Open. 2021 Oct 1; 2021 Oct 1. PMID: 34633424.
The multiple sclerosis prodrome is just unspecific symptoms in radiologically isolated syndrome patients - Commentary.Makhani N. Mult Scler. 2021 Oct; 2021 Sep 8. PMID: 34494919.
The multiple sclerosis prodrome.Makhani N, Tremlett H. Nat Rev Neurol. 2021 Aug; 2021 Jun 21. PMID: 34155379.

2020

Clinical Reasoning: A 16-year-old girl with ataxia, oscillopsia, and behavioral changes.Silverman A, Selvadurai C, Picard J, Gluck L, Fisayo A, Makhani N, Benitez V. Neurology. 2020 Apr 21; 2020 Mar 31. PMID: 32234821.
Multiple Sclerosis in Children: Current and Emerging Concepts.Brenton JN, Kammeyer R, Gluck L, Schreiner T, Makhani N. Semin Neurol. 2020 Apr; 2020 Apr 15. PMID: 32294785.
Treatment Considerations in the Radiologically Isolated Syndrome.Makhani N. Curr Treat Options Neurol. 2020 Feb 3; 2020 Feb 3. PMID: 32009206.

2019

Safety, tolerability, and efficacy of fluoxetine as an antiviral for acute flaccid myelitis.Messacar K, Sillau S, Hopkins SE, Otten C, Wilson-Murphy M, Wong B, Santoro JD, Treister A, Bains HK, Torres A, Zabrocki L, Glanternik JR, Hurst AL, Martin JA, Schreiner T, Makhani N, DeBiasi RL, Kruer MC, Tremoulet AH, Van Haren K, Desai J, Benson LA, Gorman MP, Abzug MJ, Tyler KL, Dominguez SR. Neurology. 2019 Apr 30; 2018 Nov 9. PMID: 30413631.
Oligoclonal bands increase the specificity of MRI criteria to predict multiple sclerosis in children with radiologically isolated syndrome.Makhani N, Lebrun C, Siva A, Narula S, Wassmer E, Brassat D, Brenton JN, Cabre P, Carra Dallière C, de Seze J, Durand Dubief F, Inglese M, Langille M, Mathey G, Neuteboom RF, Pelletier J, Pohl D, Reich DS, Ignacio Rojas J, Shabanova V, Shapiro ED, Stone RT, Tenembaum S, Tintoré M, Uygunoglu U, Vargas W, Venkateswaren S, Vermersch P, Kantarci O, Okuda DT, Pelletier D. Mult Scler J Exp Transl Clin. 2019 Jan-Mar; 2019 Mar 20. PMID: 30915227.
Acquisition of Early Developmental Milestones and Need for Special Education Services in Pediatric Multiple Sclerosis.Aaen G, Waltz M, Vargas W, Makhani N, Ness J, Harris Y, Casper TC, Benson L, Candee M, Chitnis T, Gorman M, Graves J, Greenberg B, Lotze T, Mar S, Tillema JM, Rensel M, Rodriguez M, Rose J, Rubin J, Schreiner T, Waldman A, Weinstock-Guttman B, Belman A, Waubant E, Krupp L. J Child Neurol. 2019 Mar; 2018 Dec 17. PMID: 30556452.

2018

The Radiologically Isolated Syndrome: An Opportunity to Prevent Multiple Sclerosis in Children.Makhani N. Pediatr Neurol. 2018 Aug; 2018 Jun 3. PMID: 30104110.

2017

Radiologically isolated syndrome in children: Clinical and radiologic outcomes.Makhani N, Lebrun C, Siva A, Brassat D, Carra Dallière C, de Seze J, Du W, Durand Dubief F, Kantarci O, Langille M, Narula S, Pelletier J, Rojas JI, Shapiro ED, Stone RT, Tintoré M, Uygunoglu U, Vermersch P, Wassmer E, Okuda DT, Pelletier D. Neurol Neuroimmunol Neuroinflamm. 2017 Nov; 2017 Sep 25. PMID: 28959703.
Abnormal Fluid-Attenuated Inversion Recovery Signal in the Internal Capsule: A Novel Brain Magnetic Resonance Imaging Finding in a Child With Acute Flaccid Myelitis.Makhani N, Mahajan A. Pediatr Neurol. 2017 Aug; 2017 Feb 7. PMID: 28262551.
MRI findings of optic pathway involvement in Miller Fisher syndrome in 3 pediatric patients and a review of the literature.Malhotra A, Zhang M, Wu X, Jindal S, Durand D, Makhani N. J Clin Neurosci. 2017 May; 2017 Feb 10. PMID: 28209311.

2016

Pediatric multiple sclerosis: Conventional first-line treatment and general management.Ghezzi A, Amato MP, Makhani N, Shreiner T, Gärtner J, Tenembaum S. Neurology. 2016 Aug 30. PMID: 27572869.
International Pediatric MS Study Group Global Members Symposium report.Wassmer E, Chitnis T, Pohl D, Amato MP, Banwell B, Ghezzi A, Hintzen RQ, Krupp LB, Makhani N, Rostásy K, Tardieu M, Tenembaum S, Waldman A, Waubant E, Kornberg AJ. Neurology. 2016 Aug 30. PMID: 27572855.
Oral Dimethyl Fumarate in Children With Multiple Sclerosis: A Dual-Center Study.Makhani N, Schreiner T. Pediatr Neurol. 2016 Apr; 2016 Jan 20. PMID: 26996405.
Radiologically Isolated Syndrome in a Pediatric Patient.George IC, DeStefano K, Makhani N. Pediatr Neurol. 2016 Mar; 2015 Nov 17. PMID: 26724214.
Viral exposures and MS outcome in a prospective cohort of children with acquired demyelination.Makhani N, Banwell B, Tellier R, Yea C, McGovern S, O'Mahony J, Ahorro JM, Arnold D, Sadovnick AD, Marrie RA, Bar-Or A. Mult Scler. 2016 Mar; 2015 Jul 21. PMID: 26199356.

2013

Incidence and prevalence of multiple sclerosis in Europe: a systematic review.Kingwell E, Marriott JJ, Jetté N, Pringsheim T, Makhani N, Morrow SA, Fisk JD, Evans C, Béland SG, Kulaga S, Dykeman J, Wolfson C, Koch MW, Marrie RA. BMC Neurol. 2013 Sep 26; 2013 Sep 26. PMID: 24070256.
Glatiramer acetate-induced acute hepatotoxicity in an adolescent with MS.Makhani N, Ngan BY, Kamath BM, Yeh EA. Neurology. 2013 Aug 27; 2013 Jul 24. PMID: 23884038.
Diagnosing neuromyelitis optica.Makhani N, Bigi S, Banwell B, Shroff M. Neuroimaging Clin N Am. 2013 May; 2013 Jan 21. PMID: 23608690.
Incidence and prevalence of multiple sclerosis in the Americas: a systematic review.Evans C, Beland SG, Kulaga S, Wolfson C, Kingwell E, Marriott J, Koch M, Makhani N, Morrow S, Fisk J, Dykeman J, Jetté N, Pringsheim T, Marrie RA. Neuroepidemiology. 2013; 2013 Jan 24. PMID: 23363936.

2011

Noninfectious central nervous system inflammatory disorders.Makhani N, Banwell B. Semin Pediatr Neurol. 2011 Jun. PMID: 22036488.
A twist on Lyme: the challenge of diagnosing European Lyme neuroborreliosis.Makhani N, Morris SK, Page AV, Brophy J, Lindsay LR, Banwell BL, Richardson SE. J Clin Microbiol. 2011 Jan; 2010 Nov 10. PMID: 21068272.

2006

Vitamin D as a neuroactive substance: review.Kiraly SJ, Kiraly MA, Hawe RD, Makhani N. ScientificWorldJournal. 2006 Jan 26; 2006 Jan 26. PMID: 16493517.