Featured Publications
Functional connectivity between task-positive and task-negative brain areas and its relation to working memory performance
Hampson M, Driesen N, Roth JK, Gore JC, Constable RT. Functional connectivity between task-positive and task-negative brain areas and its relation to working memory performance. Magnetic Resonance Imaging 2010, 28: 1051-1057. PMID: 20409665, PMCID: PMC2936669, DOI: 10.1016/j.mri.2010.03.021.Peer-Reviewed Original ResearchMeSH KeywordsAdultBrainBrain MappingFemaleFrontal LobeHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleMemoryMiddle AgedModels, StatisticalNormal DistributionConceptsDorsolateral prefrontal cortexCognitive tasksBrain areasCognitive functionPrefrontal cortexTask-negative regionsWhole-brain correlationMedial frontal cortexAnterior cingulate cortexGroup-level analysisMemory performanceFunctional brainCingulate cortexFunctional connectivityFrontal cortexFunctional connectionsCortexTaskRelationshipNegative correlationValidityConnectivityBrainFindingsRegression
2014
Optimizing real time fMRI neurofeedback for therapeutic discovery and development
Stoeckel LE, Garrison KA, Ghosh S, Wighton P, Hanlon CA, Gilman JM, Greer S, Turk-Browne NB, deBettencourt MT, Scheinost D, Craddock C, Thompson T, Calderon V, Bauer CC, George M, Breiter HC, Whitfield-Gabrieli S, Gabrieli JD, LaConte SM, Hirshberg L, Brewer JA, Hampson M, Van Der Kouwe A, Mackey S, Evins AE. Optimizing real time fMRI neurofeedback for therapeutic discovery and development. NeuroImage Clinical 2014, 5: 245-255. PMID: 25161891, PMCID: PMC4141981, DOI: 10.1016/j.nicl.2014.07.002.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsBrain MappingHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingNeurofeedbackConceptsBrain disordersBrain functionReal-time functional magnetic resonance imaging (rt-fMRI) neurofeedbackRtfMRI neurofeedbackFunctional magnetic resonance imaging (fMRI) neurofeedbackWorld Health OrganizationEffective treatmentClinical problemBrain-behavior relationshipsTherapeutic toolEffective interventionsHealth OrganizationDisordersNational InstituteIntervention approachesTherapeutic discoveryNeurofeedbackPersonalized assessmentRtfMRIMaladaptive patternsMorbidityNeurotherapeutics
2013
Real-time fMRI links subjective experience with brain activity during focused attention
Garrison KA, Scheinost D, Worhunsky PD, Elwafi HM, Thornhill TA, Thompson E, Saron C, Desbordes G, Kober H, Hampson M, Gray JR, Constable RT, Papademetris X, Brewer JA. Real-time fMRI links subjective experience with brain activity during focused attention. NeuroImage 2013, 81: 110-118. PMID: 23684866, PMCID: PMC3729617, DOI: 10.1016/j.neuroimage.2013.05.030.Peer-Reviewed Original ResearchMeSH KeywordsAdultAttentionBrain MappingFemaleGyrus CinguliHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleMeditationMiddle AgedNeurofeedbackConceptsReal-time fMRIPosterior cingulate cortexBrain activitySubjective experienceFocused attentionCingulate cortexCognitive neuroscience researchFocused attention taskOngoing subjective experienceFeedback graphsOwn brain activityDefault mode networkAttention taskNeural processesIntrospective awarenessOngoing taskRt-fMRIAffective functionsExperienced meditatorsMode networkNovel contextNeuroscience researchMeditatorsBrain imagingObjective measuresA Graphics Processing Unit Accelerated Motion Correction Algorithm and Modular System for Real-time fMRI
Scheinost D, Hampson M, Qiu M, Bhawnani J, Constable RT, Papademetris X. A Graphics Processing Unit Accelerated Motion Correction Algorithm and Modular System for Real-time fMRI. Neuroinformatics 2013, 11: 291-300. PMID: 23319241, PMCID: PMC3644525, DOI: 10.1007/s12021-013-9176-3.Peer-Reviewed Case Reports and Technical NotesMeSH KeywordsAlgorithmsBrainBrain MappingComputer GraphicsHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMotionOxygenConceptsGraphics processing unitsNovel graphics processing unitMotion correction algorithmProcessing unitReal-time methodProcessing delayCorrection algorithmSystem designMotion correction strategiesOffline methodsAlgorithmAvailable softwareReal-time functional magnetic resonance imagingModular approachValuable featuresModular systemPresent algorithmReal-time fMRIMotion correctionMotion parametersSoftwareNew technologiesNew systemCorrection strategyEstimates of motion
2010
Elevated Functional Connectivity Along a Corticostriatal Loop and the Mechanism of Auditory/Verbal Hallucinations in Patients with Schizophrenia
Hoffman RE, Fernandez T, Pittman B, Hampson M. Elevated Functional Connectivity Along a Corticostriatal Loop and the Mechanism of Auditory/Verbal Hallucinations in Patients with Schizophrenia. Biological Psychiatry 2010, 69: 407-414. PMID: 21145042, PMCID: PMC3039042, DOI: 10.1016/j.biopsych.2010.09.050.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlgorithmsAntipsychotic AgentsCerebral CortexDiagnostic and Statistical Manual of Mental DisordersFemaleFrontal LobeHallucinationsHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleNeostriatumNeural PathwaysNeuropsychological TestsPutamenSchizophreniaSchizophrenic PsychologySocioeconomic FactorsTemporal LobeVerbal BehaviorConceptsHealthy control subjectsControl subjectsFunctional connectivityNonhallucinating patientsPatient groupInferior frontal gyrusAuditory/verbal hallucinationsCorticostriatal loopsElevated functional connectivityVerbal hallucinationsFalse discovery rate correctionFunctional magnetic resonancePatientsSubcortical regionsLeft inferior frontal gyrusSeed regionPutamenFrontal gyrusSpeech processing networkFunctional coordinationNeural activitySchizophreniaFC relativeHigh levelsHallucinationsFunctional connectivity between ventral prefrontal cortex and amygdala at low frequency in the resting state in bipolar disorder
Chepenik LG, Raffo M, Hampson M, Lacadie C, Wang F, Jones MM, Pittman B, Skudlarski P, Blumberg HP. Functional connectivity between ventral prefrontal cortex and amygdala at low frequency in the resting state in bipolar disorder. Psychiatry Research 2010, 182: 207-210. PMID: 20493671, PMCID: PMC2914819, DOI: 10.1016/j.pscychresns.2010.04.002.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAmygdalaBipolar DisorderBrain MappingFemaleHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleMiddle AgedNeural PathwaysOxygenPrefrontal CortexRestYoung AdultConceptsVentral prefrontal cortexBipolar disorderFunctional connectivityPrefrontal cortexState functional magnetic resonance imagingRight ventral prefrontal cortexFunctional magnetic resonance imagingMagnetic resonance imagingWhole-brain analysisTrait abnormalityResonance imagingVentral striatumHealthy participantsAmygdalaCortexDisordersNegative correlationLow frequencyDysfunctionStriatumAbnormalitiesFunctional connectivity to a right hemisphere language center in prematurely born adolescents
Myers EH, Hampson M, Vohr B, Lacadie C, Frost SJ, Pugh KR, Katz KH, Schneider KC, Makuch RW, Constable RT, Ment LR. Functional connectivity to a right hemisphere language center in prematurely born adolescents. NeuroImage 2010, 51: 1445-1452. PMID: 20347043, PMCID: PMC2872040, DOI: 10.1016/j.neuroimage.2010.03.049.Peer-Reviewed Original ResearchConceptsFunctional connectivityWord Reading EfficiencyVerbal Comprehension IndexWechsler Intelligence ScaleRight supramarginal gyrusPeabody Picture VocabularyGreater cognitive deficitsPPVT-R scoresPhonological processingComprehension IndexLanguage tasksChildren-IIIIntelligence ScaleReading efficiencyLanguage deficitsPicture VocabularyWISC-IIISupramarginal gyrusCognitive outcomesNeurobiological basisHemisphere regionsCognitive deficitsWernicke's areaNeural activityLanguage processing