2018
Among Children Born Extremely Preterm a Higher Level of Circulating Neurotrophins Is Associated with Lower Risk of Cognitive Impairment at School Age
Kuban K, Heeren T, O'Shea T, Joseph R, Fichorova R, Douglass L, Jara H, Frazier J, Hirtz D, Taylor H, Rollins J, Paneth N, Investigators E, Ware J, Coster T, Hanson B, Wilson R, McGhee K, Lee P, Asgarian A, Sadhwani A, Perrin E, Neger E, Mattern K, Walkowiak J, Barron S, Shah B, Singh R, Smith A, Klein D, McQuiston S, Venuti L, Powers B, Foley A, Dessureau B, Wood M, Damon-Minow J, Ehrenkranz R, Benjamin J, Romano E, Tsatsanis K, Chawarska K, Kim S, Dieterich S, Bearrs K, Peters N, Brown P, Ansusinha E, Waldrep E, Friedman J, Hounshell G, Allred D, Engelke S, Darden-Saad N, Stainback G, Warner D, Wereszczak J, Bernhardt J, McKeeman J, Meyer E, Pastyrnak S, Rathbun J, Nota S, Crumb T, Lenski M, Weiland D, Lloyd M, Hunter S, Msall M, Ramoskaite R, Wiggins S, Washington K, Martin R, Prendergast B, Scott M, Klarr J, Kring B, DeRidder J, Vogt K, Yamamoto H, Ryan S, Junaid D, Dawood H, Beatty N, Luu N, Tang V, Sassi R, Pasicznyk J. Among Children Born Extremely Preterm a Higher Level of Circulating Neurotrophins Is Associated with Lower Risk of Cognitive Impairment at School Age. The Journal Of Pediatrics 2018, 201: 40-48.e4. PMID: 30029870, PMCID: PMC6684153, DOI: 10.1016/j.jpeds.2018.05.021.Peer-Reviewed Original ResearchConceptsWeeks of lifeNeurotrophic proteinsSevere cognitive impairmentBlood levelsCognitive impairmentInflammatory proteinLower riskBrain-derived neurotrophic factorNeonatal blood specimensProtein blood levelsHigh blood levelsAdverse cognitive outcomesElevated blood levelsLow Gestational Age Newborn StudyNormal T cellsYears of ageHigh exposureFunction testsNeurotrophic factorCognitive function levelT cellsReduced riskMultinomial logistic regressionElevated proteinBlood specimensHand Preference and Cognitive, Motor, and Behavioral Functioning in 10-Year-Old Extremely Preterm Children
Burnett A, Anderson P, Joseph R, Allred E, O'Shea T, Kuban K, Leviton A, Investigators E, Shah B, Singh R, Smith A, Klein D, McQuiston S, Rollins J, Douglass L, Ware J, Coster T, Henson B, Wilson R, McGhee K, Lee P, Asgarian A, Sadhwani A, Perrin E, Neger E, Mattern K, Walkowiak J, Barron S, Frazier J, Venuti L, Powers B, Foley A, Dessureau B, Wood M, Damon-Minow J, Ehrenkranz R, Benjamin J, Romano E, Tsatsanis K, Chawarska K, Kim S, Dieterich S, Bearrs K, Peters N, Brown P, Ansusinha E, Waldrep E, Friedman J, Hounshell G, Allred D, Engelke S, Darden-Saad N, Stainback G, Warner D, Wereszczak J, Bernhardt J, McKeeman J, Meyer E, Pastyrnak S, Burdo-Hartman W, Rathbun J, Nota S, Crumb T, Lenski M, Weiland D, Lloyd M, Hunter S, Msall M, Ramoskaite R, Wiggins S, Washington K, Martin R, Prendergast B, Scott M, Klarr J, Kring B, DeRidder J, Vogt K. Hand Preference and Cognitive, Motor, and Behavioral Functioning in 10-Year-Old Extremely Preterm Children. The Journal Of Pediatrics 2018, 195: 279-282.e3. PMID: 29336793, PMCID: PMC5869125, DOI: 10.1016/j.jpeds.2017.11.056.Peer-Reviewed Original ResearchMeSH KeywordsChildChild BehaviorCognitionFemaleFollow-Up StudiesFunctional LateralityHumansInfant, Extremely PrematureInfant, NewbornMaleMotor SkillsProspective Studies
2017
Antecedents of Screening Positive for Attention Deficit Hyperactivity Disorder in Ten-Year-Old Children Born Extremely Preterm
Leviton A, Hooper S, Hunter S, Scott M, Allred E, Joseph R, O'Shea T, Kuban K, Investigators E, Ware J, Coster T, Henson B, Wilson R, McGhee K, Lee P, Asgarian A, Sadhwani A, Perrin E, Neger E, Mattern K, Walkowiak J, Barron S, Frazier J, Venuti L, Powers B, Foley A, Dessureau B, Wood M, Damon-Minow J, Ehrenkranz R, Benjamin J, Romano E, Tsatsanis K, Chawarska K, Kim S, Dieterich S, Bearrs K, O'Shea T, Peters N, Brown P, Ansusinha E, Waldrep E, Friedman J, Hounshell G, Allred D, Engelke S, Darden-Saad N, Stainback G, Warner D, Wereszczak J, Bernhardt J, McKeeman J, Meyer E, Pastyrnak S, Burdo-Hartman W, Rathbun J, Nota S, Crumb T, Lenski M, Weiland D, Lloyd M, Hunter S, Msall M, Ramoskaite R, Wiggins S, Washington K, Martin R, Prendergast B, Scott M, Klarr J, Kring B, DeRidder J, Vogt K. Antecedents of Screening Positive for Attention Deficit Hyperactivity Disorder in Ten-Year-Old Children Born Extremely Preterm. Pediatric Neurology 2017, 81: 25-30. PMID: 29523493, PMCID: PMC5903941, DOI: 10.1016/j.pediatrneurol.2017.12.010.Peer-Reviewed Original ResearchMeSH KeywordsAttention Deficit Disorder with HyperactivityChildFemaleHumansInfant, Extremely PrematureInfant, NewbornInfant, Newborn, DiseasesMaleProspective StudiesRisk FactorsSocioeconomic FactorsConceptsAttention deficit hyperactivity disorderDeficit hyperactivity disorderRisk profileHyperactivity disorderRisk factorsLow socioeconomic stateLower gestational ageYoung maternal ageLow birth weightRetinopathy of prematuritySignificant risk factorsWeeks of gestationParent reportChild Symptom Inventory-4Attention deficit hyperactivity disorder (ADHD) diagnosisPostnatal day sevenAntibiotic receiptSeizure prophylaxisMaternal obesityMaternal smokingGestational ageMechanical ventilationBirth weightMaternal ageBrain scansCo-occurrence and Severity of Neurodevelopmental Burden (Cognitive Impairment, Cerebral Palsy, Autism Spectrum Disorder, and Epilepsy) at Age Ten Years in Children Born Extremely Preterm
Hirschberger R, Kuban K, O'Shea T, Joseph R, Heeren T, Douglass L, Stafstrom C, Jara H, Frazier J, Hirtz D, Rollins J, Paneth N, Investigators E, Ware J, Coster T, Hanson B, Wilson R, McGhee K, Lee P, Asgarian A, Sadhwani A, Perrin E, Neger E, Mattern K, Walkowiak J, Barron S, Shah B, Singh R, Smith A, Klein D, McQuiston S, Venuti L, Powers B, Foley A, Dessureau B, Wood M, Damon-Minow J, Ehrenkranz R, Benjamin J, Romano E, Tsatsanis K, Chawarska K, Kim S, Dieterich S, Bearrs K, Peters N, Brown P, Ansusinha E, Waldrep E, Friedman J, Hounshell G, Allred D, Engelke S, Darden-Saad N, Stainback G, Warner D, Wereszczak J, Bernhardt J, McKeeman J, Meyer E, Pastyrnak S, Rathbun J, Nota S, Crumb T, Lenski M, Weiland D, Lloyd M, Hunter S, Msall M, Ramoskaite R, Wiggins S, Washington K, Martin R, Prendergast B, Scott M, Klarr J, Kring B, DeRidder J, Vogt K. Co-occurrence and Severity of Neurodevelopmental Burden (Cognitive Impairment, Cerebral Palsy, Autism Spectrum Disorder, and Epilepsy) at Age Ten Years in Children Born Extremely Preterm. Pediatric Neurology 2017, 79: 45-52. PMID: 29310907, PMCID: PMC5803305, DOI: 10.1016/j.pediatrneurol.2017.11.002.Peer-Reviewed Original ResearchConceptsCerebral palsyAge ten yearsNeurodevelopmental impairmentCognitive impairmentProspective cohort followAutism spectrum disorderMajor neurodevelopmental impairmentPercent of childrenThird of childrenQuarter of childrenCategory ICohort followGestational ageTen yearsNumber of impairmentsChildren BornImpairment severityMultiple diagnosesIII childrenEpilepsyNormal intellectImpairmentDiagnosisCategory IIITen-year-old childrenNeurocognitive Outcomes at 10 Years of Age in Extremely Preterm Newborns with Late-Onset Bacteremia
Bright H, Babata K, Allred E, Erdei C, Kuban K, Joseph R, O'Shea T, Leviton A, Dammann O, Investigators E, Ware J, Coster T, Hanson B, Wilson R, McGhee K, Lee P, Asgarian A, Sadhwani A, Perrin E, Neger E, Mattern K, Walkowiak J, Barron S, Shah B, Singh R, Smith A, Klein D, McQuiston S, Venuti L, Powers B, Foley A, Dessureau B, Wood M, Damon-Minow J, Ehrenkranz R, Benjamin J, Romano E, Tsatsanis K, Chawarska K, Kim S, Dieterich S, Bearrs K, Peters N, Brown P, Ansusinha E, Waldrep E, Friedman J, Hounshell G, Allred D, Engelke S, Darden-Saad N, Stainback G, Warner D, Wereszczak J, Bernhardt J, McKeeman J, Meyer E, Pastyrnak S, Rathbun J, Nota S, Crumb T, Lenski M, Weiland D, Lloyd M, Hunter S, Msall M, Ramoskaite R, Wiggins S, Washington K, Martin R, Prendergast B, Scott M, Klarr J, Kring B, DeRidder J, Vogt K. Neurocognitive Outcomes at 10 Years of Age in Extremely Preterm Newborns with Late-Onset Bacteremia. The Journal Of Pediatrics 2017, 187: 43-49.e1. PMID: 28526224, PMCID: PMC5533634, DOI: 10.1016/j.jpeds.2017.04.045.Peer-Reviewed Original ResearchMeSH KeywordsBacteremiaChildDevelopmental DisabilitiesExecutive FunctionFemaleHumansInfantInfant, Extremely PrematureInfant, NewbornInfant, Premature, DiseasesMaleConceptsLate-onset bacteremiaLow gestational age newbornsGeneral cognitive abilityNeurocognitive outcomesGestational age newbornsYears of agePostnatal week 2Age 10 yearsExtremely Preterm NewbornsCognitive abilitiesExecutive functionAge newbornsNeurocognitive limitationsLower IQWeek 2Academic achievementNeurocognitive functionBirth weight z-scoreEvidence of bacteremiaLower gestational ageWeight z-scoreDefinite bacteremiaWeeks of gestationMotor domainLate bacteremiaThe Relationship of Maternal Prepregnancy Body Mass Index and Pregnancy Weight Gain to Neurocognitive Function at Age 10 Years among Children Born Extremely Preterm
Jensen E, van der Burg J, O'Shea T, Joseph R, Allred E, Heeren T, Leviton A, Kuban K, Investigators E, Shah B, Singh R, Smith A, Klein D, McQuiston S, Rollins J, Douglass L, Ware J, Coster T, Henson B, Wilson R, McGhee K, Lee P, Asgarian A, Sadhwani A, Perrin E, Neger E, Mattern K, Walkowiak J, Barron S, Frazier J, Venuti L, Powers B, Foley A, Dessureau B, Wood M, Damon-Minow J, Ehrenkranz R, Benjamin J, Romano E, Tsatsanis K, Chawarska K, Kim S, Dieterich S, Bearrs K, O'Shea T, Peters N, Brown P, Ansusinha E, Waldrep E, Friedman J, Hounshell G, Allred D, Engelke S, Darden-Saad N, Stainback G, Warner D, Wereszczak J, Bernhardt J, McKeeman J, Meyer E, Pastyrnak S, Burdo-Hartman W, Rathbun J, Nota S, Crumb T, Lenski M, Weiland D, Lloyd M, Hunter S, Msall M, Ramoskaite R, Wiggins S, Washington K, Martin R, Prendergast B, Scott M, Klarr J, Kring B, DeRidder J, Vogt K. The Relationship of Maternal Prepregnancy Body Mass Index and Pregnancy Weight Gain to Neurocognitive Function at Age 10 Years among Children Born Extremely Preterm. The Journal Of Pediatrics 2017, 187: 50-57.e3. PMID: 28341527, PMCID: PMC5533624, DOI: 10.1016/j.jpeds.2017.02.064.Peer-Reviewed Original ResearchConceptsPrepregnancy body mass indexBody mass indexMaternal prepregnancy body mass indexPregnancy weight gainMass indexNeurocognitive functionWeight gainCohort of infantsMaternal prepregnancy obesityLower scoresYears of ageAge 10 yearsFine motor controlMaternal obesityPrepregnancy weightProspective multicenterCohort studyPrepregnancy obesitySingleton pregnanciesSchool-aged childrenNeurocognitive evaluationStudy participantsBehavioral interventionsTen-year-old childrenExpression assessment
2016
Predictive Validity of the Modified Checklist for Autism in Toddlers (M-CHAT) Born Very Preterm
Kim SH, Joseph RM, Frazier JA, O'Shea TM, Chawarska K, Allred EN, Leviton A, Kuban KK, Investigators E. Predictive Validity of the Modified Checklist for Autism in Toddlers (M-CHAT) Born Very Preterm. The Journal Of Pediatrics 2016, 178: 101-107.e2. PMID: 27592094, PMCID: PMC5165696, DOI: 10.1016/j.jpeds.2016.07.052.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderBehavioral dysregulationM-CHATModified ChecklistCognitive impairmentPredictive validityGold standard diagnostic instrumentsStandard diagnostic instrumentsAge 2 yearsASD diagnosisSocioeconomic statusSpectrum disorderPreterm toddlersAge 24 monthsPreterm childrenToddlersAutismLow gestational age newbornsImpairmentSensorimotorDiagnostic instrumentAge 10 yearsVision impairmentChildrenChecklist