2008
Decrease in excitatory neurons, astrocytes and proliferating progenitors in the cerebral cortex of mice lacking exon 3 from the Fgf2 gene
Chen K, Ohkubo Y, Shin D, Doetschman T, Sanford LP, Li H, Vaccarino FM. Decrease in excitatory neurons, astrocytes and proliferating progenitors in the cerebral cortex of mice lacking exon 3 from the Fgf2 gene. BMC Neuroscience 2008, 9: 94. PMID: 18826624, PMCID: PMC2577114, DOI: 10.1186/1471-2202-9-94.Peer-Reviewed Original Research
2002
Chronic hypoxia up-regulates fibroblast growth factor ligands in the perinatal brain and induces fibroblast growth factor-responsive radial glial cells in the sub-ependymal zone
Ganat Y, Soni S, Chacon M, Schwartz ML, Vaccarino FM. Chronic hypoxia up-regulates fibroblast growth factor ligands in the perinatal brain and induces fibroblast growth factor-responsive radial glial cells in the sub-ependymal zone. Neuroscience 2002, 112: 977-991. PMID: 12088755, DOI: 10.1016/s0306-4522(02)00060-x.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBlotting, WesternCerebral CortexCerebral VentriclesEnzyme-Linked Immunosorbent AssayEpendymaFibroblast Growth Factor 1Fibroblast Growth Factor 2HypoxiaImmunohistochemistryNeurogliaRatsReceptor Protein-Tyrosine KinasesReceptor, Fibroblast Growth Factor, Type 1Receptor, Fibroblast Growth Factor, Type 2Receptors, Fibroblast Growth FactorRegenerationUp-RegulationConceptsRadial glial cellsRadial gliaChronic hypoxiaGlial cellsFibroblast growth factor 1Periventricular regionBrain lipid binding proteinMajor receptorChronic hypoxic damageGlial fibrillary acidic proteinHypoxia/ischemiaSub-ventricular zoneImmature glial cellsFibrillary acidic proteinGrowth factor-1Ependymal zoneChronic hypoxemiaCerebral cortexHypoxic damageNeurotrophin familyPerinatal brainFGF receptor 1Rat pupsPostnatal weekGlial phenotype
2000
The subcellular localization of OTX2 is cell-type specific and developmentally regulated in the mouse retina
Baas D, Bumsted KM, Martinez JA, Vaccarino FM, Wikler KC, Barnstable CJ. The subcellular localization of OTX2 is cell-type specific and developmentally regulated in the mouse retina. Brain Research 2000, 78: 26-37. PMID: 10891582, DOI: 10.1016/s0169-328x(00)00060-7.Peer-Reviewed Original ResearchMeSH Keywords3T3 CellsAnimalsAntibodiesBlotting, WesternCell NucleusCytoplasmGene Expression Regulation, DevelopmentalHomeodomain ProteinsHumansMiceMice, Inbred StrainsNerve Tissue ProteinsOtx Transcription FactorsPC12 CellsPigment Epithelium of EyeRabbitsRatsRetinal Ganglion CellsRetinal Rod Photoreceptor CellsTeratocarcinomaTrans-ActivatorsTransfectionTumor Cells, CulturedConceptsSubcellular localizationTranscription factorsHomeodomain-containing proteinCell fate determinationHomeodomain transcription factorCytoplasm of rodsFate determinationCell fateOtx2 proteinSubcellular distributionOtx2Retinal pigment epithelial cellsCell typesRod photoreceptorsPigment epithelial cellsRetinal developmentCytoplasmCell linesAdult eyesEpithelial cellsCentral nervous systemImmature rodsProteinCellsDifferential distribution