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Project Investigators List

Name Department Institution Website Project Title
James Bibb Psychiatry
University of Arizona
James A. Bibb, Ph.D. Ventral Striatal Addiction, Inflammation, and Metabolic Syndrome Signaling
Thomas Biederer Neurology Yale University Thomas Biederer, Ph.D.
Identification and Analysis of Synapse-Organizing Complexes in Addiction-Relevant Brain Regions
Kristen Brennand Psychiatry Yale University Kristen Brennand, Ph.D. Impact of Patient-Specific Perturbations in the NRXN1α Isoform Repertoire on Synaptic Composition
Sreeganga Chandra Neurology Yale University Sreeganga Chandra, Ph.D. Neuronal Substrates Required for Synapse Maintenance
Christopher Cowan
Neuroscience, Psychiatry
Medical University of South Carolina
Christopher Cowan, Ph.D.
Analysis of ROS-Sensitive HDAC5 PTMs and Identification of HDAC5 Repressor Complexes in Rats Self-Administering Cocaine or Heroin
Pietro De Camilli Cell Biology Yale University Pietro De Camilli, M.D. Membrane Traffic and Lipid Dynamics in Neuronal Function
Lakshmi Devi Pharmacology & Systems Therapeutics Icahn School of Medicine at Mount Sinai Lakshmi Devi, Ph.D. Identification of Novel Modulators of Opioid Receptor Signaling During Drug Addiction
Christie Fowler
Neurobiology and Behavior
University of California, Irvine
Christie Fowler, Ph.D .
Proteomic Analysis of the Impact of Nicotine and THC on Extracellular Vesicle Signaling
William N. Green Neurobiology University of Chicago William N. Green, Ph.D. Proteomic Assays of Nicotine-induced Golgi Fragments and Changes in Glycosylation
Stephanie Groman

Anesthesia and Critical Care

University of Chicago

Stephanie Groman, Ph.D.
Protein Mechanisms of Drug Use Susceptibility
Yasmin Hurd
Pharmacological Sciences, Neuroscience, Psychiatry
Icahn School of Medicine at Mount Sinai
Yasmin Hurd, PH.D.
Proteomic Analysis of Neural Epigenetic Mechanisms and Immune System Underlying Long-Lasting Effects of Developmental Cannabis Exposure
Leonard K. Kaczmarek Pharmacology, Cellular and Molecular Physiology Yale University Leonard K. Kaczmarek, Ph.D. Modulation of Potassium Channels by Protein Phosphorylation and Interacting Auxiliary Proteins
Paul J. Kenny Pharmacology, and Systems Therapeutics Icahn School of Medicine at Mount Sinai Paul J. Kenny, Ph.D. Mechanisms by Which Tcf7l2 Controls Addiction-relevant Gene Expression in the Habenula
Drew Kiraly
Psychiatry, Neuroscience
Wake Forest University
Drew Kiraly, M.D.; Ph.D.
Neuroimmune and Microbiome Effects on Limbic Reward Structures in Models of Substance Use Disorders
Michael R. Koelle Molecular Biophysics & Biochemistry Yale University
Michael R. Koelle, Ph.D. Proteomic Analysis of Complexes formed by the Neural G Protein Gαo
Ryan Logan
Pharmacology & Experimental Therapeutics
University of Massachusetts
Ryan Logan, Ph.D.
The Impact of Morphine on the Diurnal Variation of Protein Expression in the Dorsal Striatum
Hui-Chen Lu Psychological & Brain Sciences Indiana University at Bloomington Hui-Chen Lu, Ph.D. Mechanisms and Treatment of Adolescent Phytocannabinoid Impairment of Prefrontal Cortex Function
Ken Mackie Psychological and Brain Sciences Indiana University Ken Mackie, M.D. Effects of Phytocannabinoids on the Developing Cerebellum
Stephen J. Moss
Department of Neuroscience
Tufts University
Stephen J. Moss
Analyzing the Effects of Benzodiazepines on the Structure and Phosphorylation of Type A γ-Aminobutyric Acid Receptors
Angus Nairn Psychiatry Yale University Angus Nairn, Ph.D. Regulation of Synaptic Structure and Function by Drugs of Abuse
Eric Nestler Chair, Neuroscience Icahn School of Medicine at Mount Sinai Eric Nestler, Ph.D., M.D.
Proteomic Profiling of Drug-induced Alterations to the Brain Reward System Underlying Addiction
Marina Picciotto Psychiatry, Pharmacology, Neurobiology Yale University Marina Picciotto, Ph.D. Proteomics of Altered Signaling in Nicotine Addiction
Paul Slesinger
Icahn School of Medicine at Mount Sinai
Paul Slesinger, Ph.D.
Characterization of Changes in the GIRK Channel Proteome with Psychostimulants
Stephen Strittmatter

Neurobiology, Neurology

Yale University Stephen Strittmatter, M.D., Ph.D. Proteomic Basis for Chronic Anatomical Plasticity of Synapses
Jane Taylor Psychiatry Yale University Jane Taylor, Ph.D. Proteomic Analysis of Cellular Alterations Associated with Drug-Induced Impairments in Decision-Making, Mnemonic Processes and Relapse Behaviors
Susumu Tomita Cellular and Molecular Physiology
Yale University Susumu Tomita, Ph.D. Identification of Altered Phosphorylation Signaling in Neurotransmission
Mary Torregrossa Psychiatry University of Pittsburgh Mary Torregrossa, Ph.D. Identifying Changes in Protein Signaling that Regulate Substance Use Vulnerability, Craving, and Relapse.