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Yale/NIDA Neuroproteomics Center Pilot Project Grants



# Year

Grant Year Principal Investigator Title University Project Title


36
2019


15
Kristen Brennand
Associate Professor
Mt. Sinai School Medicine Impact of NRXN1α Alternative Splicing Changes on Synaptic Composition


35
2019


15
Yifei Cai (with Jaime Grutzendler)
Postdoctoral Associate
Yale U.
Proteomic Screening of Neuronal and Glial Subcellular Compartments Isolated by Proximity Labeling and FACS in Fixed and Fresh Brain Samples


34
2019


15
Mohammad Shahid Mansuri (with Angus Nairn)
Postdoctoral Associate Yale U.
Ultra-deep Brain Tyrosine Phosphoproteomic Profiling by SH2-Superbinder


33
2019


15
James Quinn (with Steve Arnold)
Postdoctoral Fellow
Mass. General Hospital
Analyzing the Role of Neuropeptides in the Neurobiology and Physiology of Addiction













32 2018

14 Caleb Browne (with Eric Nestler)
Postdoctoral Fellow
Mt. Sinai School Medicine Proteomic Profiling of NAc Synaptosomes During Early and Extended Withdrawal from Self-administered Cocaine


31
2018

14 Ayanabha Chakraborti (with James Bibb)
Senior Research Associate
U. Alabama at Birmingham
Profiling the Nucleus Accumbens Proteome in an Experimental Model of Inflammatory Bowel Disease


30
2018

14 Tina Franklin (with Ron Duman)
Postdoctoral Associate
Yale U.
Stress-induced Dysregulation in Microglial HMGB1 Signaling


29 2018

14 Stephanie Groman (with Jane Taylor)
Associate Research Scientist
Yale U.
A "Targeted" Approach to Identify the Proteins Underlying the Biobehavioral Mechanisms of Addiction


28 2018

14 Angela Lee (with Marina Picciotto)
MD/PhD Student
Yale U.
Sex Differences in Nicotine-induced Changes of the Mouse Brain Proteome


27 2017

13 L. Devi and D. Schechtman Professor and Assoc. Professor Mt. Sinai School Medicine and U. Sao Paulo, Brazil Identification of Protein Kinase C Targets Leading to Opioid Tolerance


26 2017

13 D. Kiraly Assistant Professor
Mt. Sinai School Medicine Characterization of Proteomic Changes in the Nucleus Accumbens in Response to Chronic Granulocyte-colony Stimulating Factor and Cocaine


25 2017

13 M. Girgenti Postdoctoral Associate Yale U. Post Mortem Proteomic Characterization of Human Subgenual Prefrontal Cortex in Tobacco Abuse and PTSD


24 2017

13 M. Wolf and A. Li Professor and Postdoctoral Associate Chicago Medical School and Behavioral Neuroscience Branch, NIDA Projection-specific Proteomics in Striatum and Its Glutamatergic Afferents in Incubation of Craving to Psychostimulants (Cocaine and Methamphetamine)


23 2016

12
T. Cijsouw (with T. Biederer)
Postdoctoral Scholar
Tufts U.
Mapping the Proteome of the Synaptic cleft Through Peroxidase-Based Reporter Proteins


22 2016

12
R. Logan
Assistant Professor
U. Pittsburgh
Identifying Circadian Regulated Proteins in Specific Cell Types of the Nucleus Accumbens involved in Cocaine Reward


21 2016

12
M. Miller (with M. Picciotto)
Postdoctoral Associate
Yale U.
A Systematic Evaluation of High-Affinity α4β2 Nicotinic Acetylcholine Receptor Phosphorylation


20 2017

12 M. Monsey (with J. Taylor) Postdoctoral Associate Yale U. Profiling the neuronal proteome of the lateral amygdala following cocaine-cue memory retrieval and systemic garcinol administration


19 2017

12 R. Taugher Postdoctoral Fellow U. Iowa Role of ASIC1A in regulating the NAc proteome in both the drug naïve and cocaine withdrawn states


18 2017

12 E. Yan Professor Yale U. Role of dimerization in modulating sensitivity and dynamic range of ligand sensing in family CG protein coupled receptors


17 2015

11
B. Carlyle (with A. Nairn)
Postdoctoral Associate
Yale U.
Assessing Proteomic Differences Between the Two Types of Major Cell Types of the Striatum


16 2015

11
A. Koleske
Professor
Yale U.
Mechanisms of Cocaine-Induced Dendritic Spine Refinement and Plasticity


15 2015

11
J. Uys (with P. Kalivas)
Assistant Professor
Medical U. South Carolina Quantitative Proteomic Analysis of S-Glutathionylated Proteins after Cocaine-Induced Reinstatement


14 2015

11
J. Xu (with P. Lombroso)
Assoc. Res. Sci.
Yale U.
Post-Translational Modification of STEP61 by BDNF Signalling: Implications in Drug Abuse


13 2012

9
R. Kitchen (with A. Nairn)
Postdoctoral Associate
Yale U.
Toward Improved Label-free Quantification of MS/MS Spectra Using Predicted Proteomes


12 2011

8
S. Chandra
Assistant Professor
Yale U.
Phosphoinositides, Synaptic Signalling, Drug Addiction, and Neurodegeneration


11 2011

8
M. Koelle
Associate Professor
Yale U.
Proteomic Analysis of Lysine Acetylation of the Neural G Protein Gαo and Its Role in Serotonin Signaling


10 2011

8
T. McClure-Begley (with M. Picciotto)
Postdoctoral Fellow
Yale U.
Defining the nAChR Interactome


9
2011

8
S. Sathyanesan
Assistant Professor
Yale U.
Development of Cerebrospinal Fluid Markers for Neuropsychiactric Disorders


8 2010

7
J. Bibb
Associate Professor
U. Texas Southwestern Medical Center
Phosphoprotein Analysis of the Effects of Cocaine on NMDA Receptor Regulation


7 2010

7
J. Rinehart
Assistant Professor
Yale U.
Global MRM Atlas of the Human Kinome


6 2010

7
A.J. Robison (with E. Nestler)
Postdoctoral Fellow
Mt. Sinai School Medicine
Neuronal Subtype-Specific Effects of the Transcription Factor delta FosB on Synaptic Physiology


5 2010

7
M. Torregrossa (with J. Taylor)
Assoc. Res. Sci.
Yale U.
Identification of Proteins that are Differentially Activated by Drug Cue memory Extinction and Reconsolidation in the Amygdala and Nucleus Accumbens Using Phosphoproteomics


4 2009

6 T. Biederer Associate Professor Yale U. Identification and Analysis of Protein Complexes Mediating Synapse Formation


3 2009

6
S. Chandra
Assistant Professor
Yale U.
Neuronal Substrates Required for Synapse Maintenance


2 2009

6
M. Morabito
Assistant Professor
U. Mass.
Cdk5-Dependent Post-translational Modifications of PSD-95


1 2009

6
S. Sathyanesan
Assistant Professor
Yale U.
A Proteomics and Genomics Characterization of the Choroid Plexus: Protein and Gene Regulation by Psychotropic Drugs