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INFORMATION FOR

Leyuan Xu, PhD

Assistant Professor

Education & Training

  • Postdoctoral Fellow
    Virginia Commonwealth University (2016)
  • PhD
    Virginia Commonwealth University, Biomedical Engineering (2015)

Activities

  • Immune-mediated Tubule Atrophy Promotes Acute Kidney Injury to Chronic Kidney Disease Transition
    Orlando, FL, United States 2022
    American Society of Nephrology
  • Single-cell RNA sequencing analysis of adaptive and maladaptive kidney repair models reveals distinct pathways of myeloid and lymphoid cell recruitment and activation
    Washington, DC, United States 2019
    American Society of Nephrology Early Program for Emerging Kidney Physiologists
  • Adaptive and maladaptive kidney repair models reveal distinct pathways of myeloid and lymphoid cell recruitment and activation
    Washington, DC, United States 2019
    American Society of Nephrology
  • Macrophage chemoattractant protein-1 (MCP-1) promotes renal fibrosis in AKI-to-CKD transition
    San Diego, CA, United States 2018
    American Society of Nephrology
  • Folate-targeted Polyamidoamine Dendrimer for Head and Neck Cancer Gene Therapy
    Charlotte, NC, United States 2015
    Society for Biomaterials
  • Synthesis and In Vitro Assessment of Folate-targeted Polyamidoamine Dendrimer Gene Vector
    Charlotte, NC, United States 2015
    Society for Biomaterials
  • Novel electrospun gelatin/insulin formulation for transbuccal insulin delivery
    San Antonio, TX, United States 2014
    Biomedical Engineering Society
  • Surface hybridization of macrophages with dendrimer via copper-free click chemistry for hypoxic tumor drug delivery
    Boston, MA, United States 2013
    Society for Biomaterials
  • Intracellular response and cytocompatibility of cells cultured with photoinitiators
    Boston, MA, United States 2013
    Society for Biomaterials
  • Induction of IκBα expression mediates the anti-inflammatory response to 25-hydroxycholesterol-3-sulfate (25HC3S) in primary rat hepatocytes and THP-1 macrophages
    Chicago, IL, United States 2011
    American Association for the Study of Liver Diseases
  • 25-Hydroxycholesterol-3-sulfate decreases hepatic steatosis and inflammation in mouse models of nonalcoholic fatty liver disease by down-regulating sterol regulatory element binding protein-1c
    Boston, MA, United States 2011
    American Association for the Study of Liver Diseases
  • 25-Hydroxycholesterol-3-sulfate (25HC3S) attenuates hepatocyte intracellular lipid levels and inflammatory response via LXR/SREBPs and IκBα/NF-κB pathways
    New Orleans, LA, United States 2010
    American Association for the Study of Liver Diseases
  • 25-Hydroxycholesterol-3-sulfate (25HC3S) suppresses NF-κB activation and inflammatory response in human macrophages and hepatocytes
    San Francisco, CA, United States 2010
    American Heart Association
  • Nuclear oxysterols, 25HC and 25HC3S, regulate nuclear orphan receptor activities and attenuate intracellular lipid levels
    New Orleans, LA, United States 2009
    The American Society for Biochemistry and Molecular Biology

Honors & Recognition

AwardAwarding OrganizationDate
American Physiological Society Travel AwardAmerican Physiological Society and American Society of Nephrology2019
Student Travel Award Recognition Honorable MentionSociety for Biomaterials2013
Graduate/Postdoctoral Travel AwardAmerican Society for Biochemistry and Molecular Biology2009

Professional Service

OrganizationRoleDate
J Am Soc NephrolReviewer2021 - Present
The FASEB JournalReviewer2020 - Present
Advanced ScienceReviewer2018 - Present
Acta BiomaterialiaReviewer2016 - Present
Journal of Materials Chemistry BReviewer2015 - Present
Advanced Healthcare MaterialsReviewer2015 - Present

Departments & Organizations