Leyuan Xu, PhD

Immune-mediated Tubule Atrophy Promotes Acute Kidney Injury to Chronic Kidney Disease Transition

Single-cell RNA sequencing analysis of adaptive and maladaptive kidney repair models reveals distinct pathways of myeloid and lymphoid cell recruitment and activation

Adaptive and maladaptive kidney repair models reveal distinct pathways of myeloid and lymphoid cell recruitment and activation

Macrophage chemoattractant protein-1 (MCP-1) promotes renal fibrosis in AKI-to-CKD transition

Folate-targeted Polyamidoamine Dendrimer for Head and Neck Cancer Gene Therapy

Synthesis and In Vitro Assessment of Folate-targeted Polyamidoamine Dendrimer Gene Vector

Novel electrospun gelatin/insulin formulation for transbuccal insulin delivery

Surface hybridization of macrophages with dendrimer via copper-free click chemistry for hypoxic tumor drug delivery

Intracellular response and cytocompatibility of cells cultured with photoinitiators

Induction of IκBα expression mediates the anti-inflammatory response to 25-hydroxycholesterol-3-sulfate (25HC3S) in primary rat hepatocytes and THP-1 macrophages

25-Hydroxycholesterol-3-sulfate decreases hepatic steatosis and inflammation in mouse models of nonalcoholic fatty liver disease by down-regulating sterol regulatory element binding protein-1c

25-Hydroxycholesterol-3-sulfate (25HC3S) attenuates hepatocyte intracellular lipid levels and inflammatory response via LXR/SREBPs and IκBα/NF-κB pathways

25-Hydroxycholesterol-3-sulfate (25HC3S) suppresses NF-κB activation and inflammatory response in human macrophages and hepatocytes

Nuclear oxysterols, 25HC and 25HC3S, regulate nuclear orphan receptor activities and attenuate intracellular lipid levels