Biostatistics Core
The primary objective of the Biostatistics Core is to provide state-of-the-art design and analytical services to investigators conducting studies that advance the Yale OAIC theme of multifactorial geriatric conditions.
The Biostatistics Core consists of faculty and staff that aim to:
- Collaborate with Pepper Scholars, Pilot and Exploratory Core investigators, the Operations Core, and investigators of external projects to achieve the mission of the Yale OAIC in promoting the understanding and treatment of multifactorial geriatric conditions
- Develop new and sound methods that address the challenges of designing and analyzing studies in basic, translational, and clinical geriatric/aging research, with special emphasis on introducing statistical methods from other disciplines
- Train the next generation of statisticians, epidemiologists and junior investigators in Gerontologic Biostatistics research methods specific to studies of multifactorial geriatric health conditions
Statistical and Analytical Services
Biostatisticians in the core can assist with analysis and design at all stages of a project from early stages of grant development (statistical methodology, power analyses) to manuscript preparation.
Collaborators
We coordinate services regularly within the Yale research community:
Publications
2025
- Spatial differentiation of carbon emissions from energy consumption based on machine learning algorithm: A case study during 2015-2020 in Shaanxi, China.Cao H, Han L, Liu M, Li L. J Environ Sci (China). 2025 Mar; 2023 Aug 22. PMID: 39181649.
2024
- Evaluation of β2-microglobulin in the condition and prognosis of psoriasis patients.Han L, Gan Y, Du J, Hu Y, Chen Y, Huang Q, Zhang Z, Yawalkar N, Yan K, Wang Z. J Dermatolog Treat. 2024 Dec; 2024 Jul 28. PMID: 39069294.
- RBM5 induces motor neuron apoptosis in hSOD1(G93A)-related amyotrophic lateral sclerosis by inhibiting Rac1/AKT pathways.Tan X, Su X, Wang Y, Liang W, Wang D, Huo D, Wang H, Qi Y, Zhang W, Han L, Zhang D, Wang M, Xu J, Feng H. Brain Res Bull. 2024 Oct 1; 2024 Aug 12. PMID: 39142444.
- Systematic analysis of serum peptidase inhibitor 3 in psoriasis diagnosis and treatment.Xu M, Deng H, Zhang X, Deng J, Yu W, Han L, Yan Y, Yao D, Yu J, Ye S, Cui J, Hu D, Jia Y, Dong Z, Xu D, Yu X, Lu C. Clin Rheumatol. 2024 Sep 17; 2024 Sep 17. PMID: 39287701.
- Inflammatory protein associations with brain MRI measures: Framingham Offspring Cohort.Chen J, Ragab AAY, Doyle MF, Alosco ML, Fang Y, Mez J, Satizabal CL, Qiu WQ, Murabito JM, Lunetta KL. Alzheimers Dement. 2024 Sep 16; 2024 Sep 16. PMID: 39282876.
- Design and implementation of a Type-2 hybrid, prospective randomized trial of opioid agonist therapies integration into primary care clinics in Ukraine.Machiavariani E, Dumchev K, Pykalo I, Filippovych M, Ivasiy R, Esserman D, Madden LM, Bromberg DJ, Haddad M, Morozova O, Ahmad B, Gómez DO, Farnum SO, Dvoriak S, Altice FL. Contemp Clin Trials. 2024 Sep 14; 2024 Sep 14. PMID: 39265780.
- Association between Silva pattern-based classification and endocervical adenocarcinoma: a systematic review and meta-analysis.Chen M, Han L, Wang Y, Chen Y, Zheng A. Int J Gynecol Cancer. 2024 Sep 13; 2024 Sep 13. PMID: 39277184.
- "Faith and a sunny day": Association of patient frailty with strain experienced by informal caregivers of older adults with non-muscle-invasive bladder cancer.Garg T, Maheshwari C, Frank K, Johns A, Rabinowitz K, Danella JF, Becker H, Kirchner HL, Nielsen ME, Cohen HJ, Murphy TE, McMullen CK. J Geriatr Oncol. 2024 Sep 7; 2024 Sep 7. PMID: 39244892.
- The minimally invasive resection of port-site metastasis of ovarian cancer after laparoscopy with cutaneous integrity: a case report and literature review.Han L, Liu W, Shi G, Zheng A, Ruan J. BMC Womens Health. 2024 Sep 6; 2024 Sep 6. PMID: 39242540.
- Gene expression and splicing QTL analysis of blood cells in African American participants from the Jackson Heart Study.Wen J, Sun Q, Huang L, Zhou L, Doyle MF, Ekunwe L, Durda P, Olson NC, Reiner AP, Li Y, Raffield LM. Genetics. 2024 Sep 4. PMID: 39056362.
- Whole-genome analysis of plasma fibrinogen reveals population-differentiated genetic regulators with putative liver roles.Huffman JE, Nicholas J, Hahn J, Heath AS, Raffield LM, Yanek LR, Brody JA, Thibord F, Almasy L, Bartz TM, Bielak LF, Bowler RP, Carrasquilla GD, Chasman DI, Chen MH, Emmert DB, Ghanbari M, Haessler J, Hottenga JJ, Kleber ME, Le NQ, Lee J, Lewis JP, Li-Gao R, Luan J, Malmberg AL, Mangino M, Marioni R, Martinez-Perez A, Pankratz N, Polasek O, Richmond A, Rodriguez BAT, Rotter JI, Steri M, Suchon P, Trompet S, Weiss S, Zare M, Auer PL, Cho M, Christofidou P, Davies G, de Geus EJ, Deleuze JF, Delgado GE, Ekunwe L, Faraday N, Gogele M, Greinacher A, Gao H, Howard TE, Joshi PK, Kilpeläinen TO, Lahti J, Linneberg A, Naitza S, Noordam R, Vergés FP, Rich SS, Rosendaal FR, Rudan I, Ryan KA, Souto JCC, van Rooij FJA, Wang H, Zhao W, Becker L, Beswick A, Brown MR, Cade B, Campbell H, Cho K, Crapo J, Curran J, de Maat MPM, Doyle MF, Elliott P, Floyd JS, Fuchsberger C, Grarup N, Guo X, Harris S, Hou L, Kolcic I, Kooperberg C, Menni C, Nauck M, O'Connell JR, Orru V, Psaty BM, Räikkönen K, Smith JA, Soria JM, Stott D, van Hylckama Vlieg A, Watkins H, Willemsen G, Wilson PW, Ben-Shlomo Y, Blangero J, Boomsma D, Cox SR, Dehghan A, Eriksson JG, Fiorillo E, Fornage M, Hansen T, Hayward C, Ikram MA, Jukema JW, Kardia S, Lange L, Maerz W, Mathias R, Mitchell BD, Mook-Kanamori DO, Morange PE, Pedersen O, Pramstaller PP, Redline S, Reiner AP, Ridker PM, Silverman EK, Spector TD, Volker U, Wareham N, Wilson J, Yao J, Tregouet DA, Johnson AD, Wolberg AS, de Vries PS, Sabater-Lleal M, Morrison A, Smith NL. Blood. 2024 Sep 3; 2024 Sep 3. PMID: 39226462.
- High-resolution carbon emission mapping and spatial-temporal analysis based on multi-source geographic data: A case study in Xi'an City, China.Liu Z, Han L, Liu M. Environ Pollut. 2024 Sep 1; 2024 Sep 1. PMID: 39226983.
- Randomized Clinical Trials That Advance Health and Health Equity: JAMA Internal Medicine Call for Papers.Wang TY, Corbie G, Allore HG, Anderson TS, Durant R, Ganguli I, Grady D, Gross CP, Katz M, Mody L, Tripodis Y, Inouye SK. JAMA Intern Med. 2024 Sep 1. PMID: 39008289.
- Is pharmacologic venous Thromboprophylaxis necessary for patients undergoing minimally invasive surgery for endometrial Cancer? A systematic review and Meta-analysis.Chen H, Chen Y, Zheng A, Tan X, Han L. Gynecol Oncol. 2024 Sep; 2024 Jun 19. PMID: 38901080.
- Functional disability and receipt of informal care among Chinese adults living alone with cognitive impairment.Liu X, Li C, Jin S, Cao X, Hoogendijk EO, Han L, Xu X, Allore H, Feng Q, Zhang Q, Liu Z. Exp Gerontol. 2024 Sep; 2024 Jun 18. PMID: 38876449.
- Effect of a Three-Component Geriatrics Bundle on Incident Delirium among Critically Ill Older Adults: A Pilot Clinical Trial.Ferrante LE, Han L, Andrews B, Cohen AB, Davis JL, Gritsenko D, Lee S, Pisani MA, Reed NS, Rouse G, Truebig J. Ann Am Thorac Soc. 2024 Sep. PMID: 38785442.
- Tapioca starch/konjac gum-based composite film incorporated with nanoliposomes encapsulated grape seed oil: Structure, functionality, controlled release and its preservation role for chilled mutton.Song Z, Zang Z, Cao Y, Ma Y, Li B, Han L, Yu Q. Food Chem. 2024 Aug 31; 2024 Aug 31. PMID: 39243627.
- Effect of tremella polysaccharides on the quality of collagen jelly: insight into the improvement of the gel properties and the antioxidant activity of yak skin gelatin.Zhang Y, Han G, Wang X, Wang Y, Wang M, Li Y, Yu Q, Han L. J Sci Food Agric. 2024 Aug 30; 2024 Apr 17. PMID: 38572795.
- The synergistic effect of high temperature and relative humidity on non-accidental deaths at different urbanization levels.Bu Y, Sun Z, Tao Y, Zhao X, Zhao Y, Liang Y, Hang X, Han L. Sci Total Environ. 2024 Aug 25; 2024 May 31. PMID: 38823719.
- [Analysis of the Spatiotemporal Evolution of Carbon Reserves in Shaanxi Province Under Different Scenarios in the Future].Qu SJ, Han L, Huang X, Yang NN, Guo QH. Huan Jing Ke Xue. 2024 Aug 8. PMID: 39168687.
- Elusive Protein-Glycosphingolipid Interactions Revealed by Membrane Anchor-Assisted Native Mass Spectrometry.Favell JW, Bui DT, Li J, Han L, Kitova EN, Schmidt EN, Brassard R, Kitov PI, St-Pierre Y, Mahal LK, Lemieux MJ, Macauley MS, Klassen JS. J Am Chem Soc. 2024 Aug 7; 2024 Jul 25. PMID: 39052014.
- Risk of Serious Adverse Gastrointestinal Events with Potassium Binders in Hospitalized Patients: A National Study.Holleck JL, Han L, Skanderson M, Bastian LA, Gunderson CG, Brandt CA, Perkal M, Chang JJ, Akgün KM. J Gen Intern Med. 2024 Aug 5; 2024 Aug 5. PMID: 39103605.
- Construction of ecological security pattern in combination with landslide sensitivity: A case study of Yan'an City, China.Li B, Han L, Li L. J Environ Manage. 2024 Aug; 2024 Jul 19. PMID: 39029175.
- Prenatal diagnosis of severe hydrocephalus caused by fetal intracranial pineal gland tumors.Lv B, Zheng A, Han L. Am J Obstet Gynecol. 2024 Aug; 2024 Feb 14. PMID: 38365099.
- Hierarchical Bayesian modeling of heterogeneous outcome variance in cluster randomized trials.Tong G, Tong J, Jiang Y, Esserman D, Harhay MO, Warren JL. Clin Trials. 2024 Aug; 2024 Jan 10. PMID: 38197388.
- Associations of circulating T-cell subsets in carotid artery stiffness: the Multi-Ethnic Study of Atherosclerosis.DeConne TM, Buzkova P, Pewowaruk R, Delaney JA, Psaty BM, Tracy RP, Doyle MF, Sitlani CM, Landay AL, Huber SA, Hughes TM, Bertoni AG, Gepner AD, Olson NC, Ding J. medRxiv. 2024 Jul 31; 2024 Jul 31. PMID: 39132475.
- Immune cell profiling of the ICAM1 p.K56M heart failure with preserved ejection fraction risk variant.Gao J, Giro P, Delaney JA, Rasmussen-Torvik L, Taylor KD, Thorp EB, Doyle MF, Feinstein MJ, Sitlani CM, Olson N, Tracy R, Shah SJ, Psaty BM, Patel RB. ESC Heart Fail. 2024 Jul 22; 2024 Jul 22. PMID: 39034892.
- Phase I Study of GS-3583, an FMS-like Tyrosine Kinase 3 Agonist Fc Fusion Protein, in Patients with Advanced Solid Tumors.Tolcher AW, Brody JD, Rajakumaraswamy N, Kuhne M, Trowe T, Dauki AM, Pai S, Han L, Lin KW, Petrarca M, Kummar S. Clin Cancer Res. 2024 Jul 15. PMID: 38295150.
- Patients with High Baseline Neutrophil-to-Lymphocyte Ratio Exhibit Better Response to Filgotinib as Treatment for Rheumatoid Arthritis.Taylor PC, Downie B, Han L, Hawtin R, Hertz A, Moots RJ, Takeuchi T. Rheumatol Ther. 2024 Jul 10; 2024 Jul 10. PMID: 38985247.
- Multimorbidity and associated informal care receiving characteristics for US older adults: a latent class analysis.Liu R, Nagel CL, Chen S, Newsom JT, Allore HG, Quiñones AR. BMC Geriatr. 2024 Jul 3; 2024 Jul 3. PMID: 38956501.
- Preadsorbed Chymotrypsin Modulated the Composition of Protein Corona and Immunological Response.Han L, Wang Y, Jia H, Zhang Z, Yang S, Li F, Li F, Yang H. ACS Omega. 2024 Jul 2; 2024 Jun 17. PMID: 38973854.
- In-Hospital Delirium and Disability and Cognitive Impairment After COVID-19 Hospitalization.Kaushik R, McAvay GJ, Murphy TE, Acampora D, Araujo K, Charpentier P, Chattopadhyay S, Geda M, Gill TM, Kaminski TA, Lee S, Li J, Cohen AB, Hajduk AM, Ferrante LE. JAMA Netw Open. 2024 Jul 1; 2024 Jul 1. PMID: 38954414.
- Potato oxidized hydroxypropyl starch/pectin-based indicator film with Clitoria ternatea anthocyanin and silver nanoparticles for monitoring chilled beef freshness.Cao Y, Song Z, Dong C, Zhang L, Yu Q, Han L. Int J Biol Macromol. 2024 Jul; 2024 Jun 13. PMID: 38876228.
- The most recent progress of baicalein in its anti-neoplastic effects and mechanisms.Lei C, Yu Y, Zhu Y, Li Y, Ma C, Ding L, Han L, Zhang H. Biomed Pharmacother. 2024 Jul; 2024 Jun 7. PMID: 38850656.
- Leveraging Electronic Health Records to Assess Residential Mobility Among Veterans in the Veterans Health Administration.Wang KH, Hendrickson ZM, Miller ML, Abel EA, Skanderson M, Erdos J, Womack JA, Brandt CA, Desai M, Han L. Med Care. 2024 Jul 1; 2024 Jun 7. PMID: 38848139.
- Splenectomy as a part of cytoreductive surgery in ovarian cancer: systematic review and meta-analysis.Wang Y, Chen Y, Qin Z, Chen M, Zheng A, Han L. Int J Gynecol Cancer. 2024 Jul 1; 2024 Jul 1. PMID: 38839080.
- Value in Optimizing the Components of App Interventions Before Final Testing.Allore HG, Katz MH. JAMA Intern Med. 2024 Jul 1. PMID: 38805201.
- Recommendations on Methods for Assessing Multimorbidity Changes Over Time: Aligning the Method to the Purpose.Nagel CL, Bishop NJ, Botoseneanu A, Allore HG, Newsom JT, Dorr DA, Quiñones AR. J Gerontol A Biol Sci Med Sci. 2024 Jul 1. PMID: 38742711.
- Assessing readiness to use electronic health record data for outcome ascertainment in clinical trials - A case study.Esserman D, Greene EJ, Latham NK, Kane M, Lu C, Peduzzi PN, Gill TM, Ganz DA. Contemp Clin Trials. 2024 Jul; 2024 May 11. PMID: 38740298.
- Validation of a Rule-Based ICD-10-CM Algorithm to Detect Fall Injuries in Medicare Data.Ganz DA, Esserman D, Latham NK, Kane M, Min LC, Gill TM, Reuben DB, Peduzzi P, Greene EJ. J Gerontol A Biol Sci Med Sci. 2024 Jul 1. PMID: 38566617.
- Variation in Specialist Palliative Care Reach and Associated Factors Among People With Advanced Heart Failure in the Department of Veterans Affairs.Feder SL, Han L, Zhan Y, Abel EA, Akgün KM, Fried T, Ersek M, Redeker NS. J Pain Symptom Manage. 2024 Jul; 2024 Mar 30. PMID: 38561132.
- Association between diet quality and ovarian cancer risk and survival.Cao A, Esserman DA, Cartmel B, Irwin ML, Ferrucci LM. J Natl Cancer Inst. 2024 Jul 1. PMID: 38400738.
- Association Between Rental Assistance Programs and Undiagnosed Diabetes Among U.S.Gonzalez-Lopez C, Fenelon A, Lipska KJ, Denary W, Schlesinger P, Esserman D, Keene D. J Gen Intern Med. 2024 Jul; 2024 Feb 13. PMID: 38351417.
- Identification of an exosomal miRNA-mRNA regulatory network contributing to methotrexate efficacy.Zhang M, Niu Z, Huang Q, Han L, Du J, Liang J, Cheng Y, Cao R, Yawalkar N, Zhang Z, Yan K. Int Immunopharmacol. 2024 Jun 30; 2024 May 21. PMID: 38776848.
- Cowhide gelatin peptide as a source of antioxidants for inhibiting the deterioration of pudding quality during storage.Wang W, Zhao Y, He L, Song Z, Shi C, Jia P, Yu Q, Han L. Food Chem X. 2024 Jun 30; 2024 Mar 26. PMID: 38590633.
- Causal associations between psoriasis, eczema, urticaria, and mental illness: A bidirectional Mendelian randomization study of the European population.Mo N, Yang Y, Wang W, Zhou P, Liu F, Zhang Y, Zhang J, Han L, Lu C. Medicine (Baltimore). 2024 Jun 28. PMID: 38941419.
- Genomic correlation, shared loci, and causal relationship between insomnia and psoriasis: a large-scale genome-wide cross-trait analysis.Wang Q, Wu Y, Wang X, Zhang J, Li L, Wu J, Lu Y, Han L. Arch Dermatol Res. 2024 Jun 21; 2024 Jun 21. PMID: 38904754.
- Effects of cannabidiol, with and without ∆9-tetrahydrocannabinol, on anxiety-like behavior following alcohol withdrawal in mice.Melkumyan M, Annaswamy VM, Evans AM, Showemimo OF, McCullers ZE, Sun D, Murphy TE, Vrana KE, Arnold AC, Raup-Konsavage WM, Silberman Y. Front Neurosci. 2024; 2024 Jun 18. PMID: 38957186.
- Vitamin D supplementation during pregnancy and the role of maternal prenatal depression.Lv B, Zheng A, Han L. BMC Pregnancy Childbirth. 2024 Jun 18; 2024 Jun 18. PMID: 38890581.
- The Benefit of the Optimized Formula of Yinxieling in Psoriasis Vulgaris via Regulation on Autophagy Based on microRNA Expression Profile and Network Pharmacology Analysis.Lu Y, Pan S, Li W, Qi Y, Li L, Yan YH, Wei J, Yao DN, Wu J, Deng H, Ye S, Chen H, Chen Q, Gao H, Han L, Lu C. Drug Des Devel Ther. 2024; 2024 Jun 14. PMID: 38895176.
- Immune cell phenotypes and mortality in the Framingham Heart Study.Ragab AAY, Doyle MF, Chen J, Fang Y, Lunetta KL, Murabito JM. Immun Ageing. 2024 Jun 12; 2024 Jun 12. PMID: 38867269.
- Bayesian semi-parametric inference for clustered recurrent events with zero inflation and a terminal event.Tian X, Ciarleglio M, Cai J, Greene EJ, Esserman D, Li F, Zhao Y. J R Stat Soc Ser C Appl Stat. 2024 Jun; 2024 Feb 1. PMID: 39072299.
- Stiffening of the human proximal pulmonary artery with increasing age.Manning EP, Mishall P, Ramachandra AB, Hassab AHM, Lamy J, Peters DC, Murphy TE, Heerdt P, Singh I, Downie S, Choudhary G, Tellides G, Humphrey JD. Physiol Rep. 2024 Jun. PMID: 38884325.
- Anti-psoriasis effect of 18β-glycyrrhetinic acid by breaking CCL20/CCR6 axis through its vital active group targeting GUSB/ATF2 signaling.Wei J, Zhang J, Hu F, Zhang W, Wu Y, Liu B, Lu Y, Li L, Han L, Lu C. Phytomedicine. 2024 Jun; 2024 Mar 16. PMID: 38552435.
- Two new anti-inflammatory compounds from the roots and rhizomes of Clematis terniflora var. manshurica (Rupr.) Ohwi.Shao P, Dong S, Mu LT, Han L, Lv CN, Yuan JZ, Lu JC. Nat Prod Res. 2024 Jun; 2023 Jul 3. PMID: 37395431.
- A rare case report of endometrial adenosarcoma in the cesarean scar diverticulum.Han L, Shi G, Ruan J. Transl Cancer Res. 2024 May 31; 2024 May 28. PMID: 38881921.
- A Bayesian platform trial design with hybrid control based on multisource exchangeability modelling.Wei W, Blaha O, Esserman D, Zelterman D, Kane M, Liu R, Lin J. Stat Med. 2024 May 30; 2024 Apr 9. PMID: 38594809.
- Molecular Characterization of Resistance and Virulence Factors of Trueperella pyogenes Isolated from Clinical Bovine Mastitis Cases in China.Zheng Y, Yu Q, Han L, Chen X. Infect Drug Resist. 2024; 2024 May 20. PMID: 38800580.
- Mental-somatic multimorbidity in trajectories of cognitive function for middle-aged and older adults.Chen S, Nagel CL, Liu R, Botoseneanu A, Allore HG, Newsom JT, Thielke S, Kaye J, Quiñones AR. PLoS One. 2024; 2024 May 14. PMID: 38743678.
- Toripalimab plus cetuximab combined with radiotherapy in a locally advanced platinum-based chemotherapy-insensitive nasopharyngeal carcinoma patient: a case report.Piao Y, Yang Y, Wu S, Han L. Front Oncol. 2024; 2024 May 10. PMID: 38800412.
- Determinants of mosaic chromosomal alteration fitness.Pershad Y, Mack T, Poisner H, Jakubek YA, Stilp AM, Mitchell BD, Lewis JP, Boerwinkle E, Loos RJF, Chami N, Wang Z, Barnes K, Pankratz N, Fornage M, Redline S, Psaty BM, Bis JC, Shojaie A, Silverman EK, Cho MH, Yun JH, DeMeo D, Levy D, Johnson AD, Mathias RA, Taub MA, Arnett D, North KE, Raffield LM, Carson AP, Doyle MF, Rich SS, Rotter JI, Guo X, Cox NJ, Roden DM, Franceschini N, Desai P, Reiner AP, Auer PL, Scheet PA, Jaiswal S, Weinstock JS, Bick AG. Nat Commun. 2024 May 7; 2024 May 7. PMID: 38714703.
- High Blood Pressure in Children Aged 3 to 12 Years Old With Overweight or Obesity.Nugent JT, Maciejewski KR, Finn EB, Grout RW, Wood CT, Esserman D, Michel JJ, Lu Y, Sharifi M. Child Obes. 2024 May 3; 2024 May 3. PMID: 38700557.
- A genetic association study of circulating coagulation factor VIII and von Willebrand factor levels.de Vries PS, Reventun P, Brown MR, Heath AS, Huffman JE, Le NQ, Bebo A, Brody JA, Temprano-Sagrera G, Raffield LM, Ozel AB, Thibord F, Jain D, Lewis JP, Rodriguez BAT, Pankratz N, Taylor KD, Polasek O, Chen MH, Yanek LR, Carrasquilla GD, Marioni RE, Kleber ME, Trégouët DA, Yao J, Li-Gao R, Joshi PK, Trompet S, Martinez-Perez A, Ghanbari M, Howard TE, Reiner AP, Arvanitis M, Ryan KA, Bartz TM, Rudan I, Faraday N, Linneberg A, Ekunwe L, Davies G, Delgado GE, Suchon P, Guo X, Rosendaal FR, Klaric L, Noordam R, van Rooij F, Curran JE, Wheeler MM, Osburn WO, O'Connell JR, Boerwinkle E, Beswick A, Psaty BM, Kolcic I, Souto JC, Becker LC, Hansen T, Doyle MF, Harris SE, Moissl AP, Deleuze JF, Rich SS, van Hylckama Vlieg A, Campbell H, Stott DJ, Soria JM, de Maat MPM, Almasy L, Brody LC, Auer PL, Mitchell BD, Ben-Shlomo Y, Fornage M, Hayward C, Mathias RA, Kilpeläinen TO, Lange LA, Cox SR, März W, Morange PE, Rotter JI, Mook-Kanamori DO, Wilson JF, van der Harst P, Jukema JW, Ikram MA, Blangero J, Kooperberg C, Desch KC, Johnson AD, Sabater-Lleal M, Lowenstein CJ, Smith NL, Morrison AC. Blood. 2024 May 2. PMID: 38320121.
- Social Determinants of Health and Delivery of Rehabilitation to Older Adults During ICU Hospitalization.Jain S, Murphy TE, Falvey JR, Leo-Summers L, O'Leary JR Jr, Zang E, Gill TM, Krumholz HM, Ferrante LE. JAMA Netw Open. 2024 May 1; 2024 May 1. PMID: 38728030.
- Integrated longitudinal multiomics study identifies immune programs associated with acute COVID-19 severity and mortality.Gygi JP, Maguire C, Patel RK, Shinde P, Konstorum A, Shannon CP, Xu L, Hoch A, Jayavelu ND, Haddad EK, Reed EF, Kraft M, McComsey GA, Metcalf JP, Ozonoff A, Esserman D, Cairns CB, Rouphael N, Bosinger SE, Kim-Schulze S, Krammer F, Rosen LB, van Bakel H, Wilson M, Eckalbar WL, Maecker HT, Langelier CR, Steen H, Altman MC, Montgomery RR, Levy O, Melamed E, Pulendran B, Diray-Arce J, Smolen KK, Fragiadakis GK, Becker PM, Sekaly RP, Ehrlich LI, Fourati S, Peters B, Kleinstein SH, Guan L. J Clin Invest. 2024 May 1; 2024 May 1. PMID: 38690733.
- Associations of Social Support With Physical and Mental Health Symptom Burden After COVID-19 Hospitalization Among Older Adults.Lee S, McAvay GJ, Geda M, Chattopadhyay S, Acampora D, Araujo K, Charpentier P, Gill TM, Hajduk AM, Cohen AB, Ferrante LE. J Gerontol A Biol Sci Med Sci. 2024 May 1. PMID: 38558166.
- Characterization of sodium alginate-carrageenan films prepared by adding peanut shell flavonoids as an antioxidant: Application in chilled pork preservation.Wang C, Song Z, Cao Y, Han L, Yu Q, Han G, Zhu X. Int J Biol Macromol. 2024 May; 2024 Mar 27. PMID: 38552691.
- Improving Women's Health Across the Life Span-JAMA Internal Medicine Call for Papers.Grady D, Allore HG, Corbie G, Covinsky KE, Durant RW, Ganguli I, Gross CP, Katz MH, Mody L, Wang T, Tripodis Y, Inouye SK. JAMA Intern Med. 2024 May 1. PMID: 38497973.
- Prognostic value of three-tiered scoring system for lymph-vascular space invasion in endometrial cancer: A systematic review and meta-analysis.Han L, Chen Y, Zheng A, Tan X, Chen H. Gynecol Oncol. 2024 May; 2024 Feb 9. PMID: 38335803.
- Longitudinal Care Network Changes and Associated Healthcare Utilization Among Care Recipients.Liu R, Wyk BV, Quiñones AR, Allore HG. Res Aging. 2024 May-Jun; 2024 Jan 23. PMID: 38261524.
- Deep learning insights into the architecture of the mammalian egg-sperm fusion synapse.Elofsson A, Han L, Bianchi E, Wright GJ, Jovine L. Elife. 2024 Apr 26; 2024 Apr 26. PMID: 38666763.
- Potential functionality of Cutibacterium acnes extracellular vesicles in atopic dermatitis and acne vulgaris: A comparative proteomic analysis.Yu T, Chen J, Wu S, Jiang M, Han L, Ma Y. Proteomics Clin Appl. 2024 Apr 19; 2024 Apr 19. PMID: 38639920.
- Design, synthesis and herbicidal activity of novel cyclohexanedione derivations containing pyrazole and pyridine groups as potential HPPD inhibitors.Hou ST, Han L, Li WR, Dai GY, Liu Y, Lu AM, Yang CL, Chen M. Mol Divers. 2024 Apr 13; 2024 Apr 13. PMID: 38609691.
- Emergence of Astrakhan rickettsial fever in China.Teng ZQ, Yang L, Zhao N, Li XT, Dai LP, Zhang X, Shao TT, Han L, Zheng RJ, Wen BH, Kan B, Xu JG, Lu XB, Qin T. J Infect. 2024 Apr; 2024 Mar 8. PMID: 38462076.
- Roflupram alleviates autophagy defects and reduces mutant hSOD1-induced motor neuron damage in cell and mouse models of amyotrophic lateral sclerosis.Huo D, Liang W, Wang D, Liu Q, Wang H, Wang Y, Zhang C, Cong C, Su X, Tan X, Zhang W, Han L, Zhang D, Wang M, Feng H. Neuropharmacology. 2024 Apr 1; 2024 Jan 12. PMID: 38218579.
- Derivation and validation of a noninvasive prediction tool to identify pulmonary hypertension in patients with IPF: Evolution of the model FORD.Nathan SD, Chandel A, Wang Y, Xu J, Shao L, Watkins TR, Diviney J, King CS, Han L. J Heart Lung Transplant. 2024 Apr; 2023 Nov 17. PMID: 37979926.
- Effect of glycolysis on water holding capacity during postmortem aging of Jersey cattle-yak meat.Shi C, Wang L, Xu J, Li A, Wang C, Zhu X, Wang W, Yu Q, Han L. J Sci Food Agric. 2024 Mar 30; 2024 Jan 12. PMID: 38057148.
- Investigating peripheral blood monocyte and T-cell subsets as non-invasive biomarkers for asymptomatic hepatic steatosis: results from the Multi-Ethnic Study of Atherosclerosis.Niedecker RW, Delaney JA, Doyle MF, Sparks AD, Sitlani CM, Buzkova P, Zeb I, Tracy RP, Psaty BM, Budoff MJ, Olson NC. Front Immunol. 2024; 2024 Mar 26. PMID: 38596669.
- Potential Effects of NO-Induced Hypoxia-Inducible Factor-1α on Yak Meat Tenderness during Post-Mortem Aging.Sun N, Wang Z, Zhu X, Tan S, Song R, Shi W, Han L, Yu Q. J Agric Food Chem. 2024 Mar 20; 2024 Mar 11. PMID: 38466638.
- A genome-wide cross-trait analysis identifies shared loci and causal relationships of obesity and lipidemic traits with psoriasis.Wu Y, Huang M, Chen X, Wu J, Li L, Wei J, Lu C, Han L, Lu Y. Front Immunol. 2024; 2024 Mar 14. PMID: 38550599.
- ZP2 cleavage blocks polyspermy by modulating the architecture of the egg coat.Nishio S, Emori C, Wiseman B, Fahrenkamp D, Dioguardi E, Zamora-Caballero S, Bokhove M, Han L, Stsiapanava A, Algarra B, Lu Y, Kodani M, Bainbridge RE, Komondor KM, Carlson AE, Landreh M, de Sanctis D, Yasumasu S, Ikawa M, Jovine L. Cell. 2024 Mar 14. PMID: 38490181.
- Venous thromboembolism swine model with reflux-induced venous hypertension.Wang M, Lu X, Han L, Diaz JA, Raju S, Kassab GS. JVS Vasc Sci. 2024; 2024 Mar 13. PMID: 38766270.
- [Potential Ecological Risk Assessment of Soil Heavy Metals in Fengdong New District Based on Information Diffution Model].Yang NN, Han L, Liu M. Huan Jing Ke Xue. 2024 Mar 8. PMID: 38471886.
- Joint superpixel and Transformer for high resolution remote sensing image classification.Dang G, Mao Z, Zhang T, Liu T, Wang T, Li L, Gao Y, Tian R, Wang K, Han L. Sci Rep. 2024 Mar 1; 2024 Mar 1. PMID: 38424135.
- Changing epidemiologic patterns of typhus group rickettsiosis and scrub typhus in China, 1950-2022.Han L, Zhang Y, Jin X, Ren H, Teng Z, Sun Z, Xu J, Qin T. Int J Infect Dis. 2024 Mar; 2023 Dec 30. PMID: 38163619.
- Minimally Invasive Resection of Ovarian Leiomyoma.Han L, Shi G, Ruan J. J Minim Invasive Gynecol. 2024 Mar; 2023 Dec 1. PMID: 38043861.
- Spontaneous abdominal wall blood vessel rupture as a rare complication of severe pre-eclampsia.Bin L, Han L. Int J Gynaecol Obstet. 2024 Mar; 2023 Nov 27. PMID: 38009360.
- High pressure-assisted enzymatic hydrolysis promotes the release of a bi-functional peptide from cowhide gelatin with dipeptidyl peptidase IV (DPP-IV) inhibitory and antioxidant activities.He L, Han L, Yu Q, Wang X, Li Y, Han G. Food Chem. 2024 Mar 1; 2023 Sep 20. PMID: 37748255.
- Demographic and Clinical Factors Associated With SARS-CoV-2 Spike 1 Antibody Response Among Vaccinated US Adults: the C4R Study.Kim JS, Sun Y, Balte P, Cushman M, Boyle R, Tracy RP, Styer LM, Bell TD, Anderson MR, Allen NB, Schreiner PJ, Bowler RP, Schwartz DA, Lee JS, Xanthakis V, Doyle MF, Regan EA, Make BJ, Kanaya AM, Wenzel SE, Coresh J, Isasi CR, Raffield LM, Elkind MSV, Howard VJ, Ortega VE, Woodruff P, Cole SA, Henderson JM, Mantis NJ, Parker MM, Demmer RT, Oelsner EC. Nat Commun. 2024 Feb 19; 2024 Feb 19. PMID: 38374032.
- Profile of Caregiving Activities and Association With Physical Health Among Dementia Spousal Caregivers.Cho J, Sands LP, Stevens AB, Allore HG, Horstman MJ. Innov Aging. 2024; 2024 Feb 15. PMID: 38524243.
- Network pharmacology and gut microbiota insights: unraveling Shenling Baizhu powder's role in psoriasis treatment.Tang B, Zheng X, Luo Q, Li X, Yang Y, Bi Y, Chen Y, Han L, Chen H, Lu C. Front Pharmacol. 2024; 2024 Feb 14. PMID: 38425649.
- Theory of four wave mixing-based parametric amplification of spin-orbit modes.Elder HF, Dacha SK, Murphy TE, Sprangle P. Opt Express. 2024 Feb 12. PMID: 38439350.
- Prior Influenza Infection Mitigates SARS-CoV-2 Disease in Syrian Hamsters.Di Pietro C, Haberman AM, Lindenbach BD, Smith PC, Bruscia EM, Allore HG, Vander Wyk B, Tyagi A, Zeiss CJ. Viruses. 2024 Feb 3; 2024 Feb 3. PMID: 38400021.
- Filgotinib Demonstrates Efficacy in Rheumatoid Arthritis Independent of Smoking Status: Post Hoc Analysis of Phase 3 Trials and Claims-Based Analysis.Curtis JR, Emery P, Downie B, Zhong Y, Liu J, Han L, Hawtin RE, Burmester GR. Rheumatol Ther. 2024 Feb; 2023 Dec 6. PMID: 38057656.
- Geriatric assessment-derived deficit accumulation and patient-reported treatment burden in older adults with bladder cancer.Garg T, Frank K, Johns A, Rabinowitz K, Danella JF, Kirchner HL, Nielsen ME, McMullen CK, Murphy TE, Cohen HJ. J Am Geriatr Soc. 2024 Feb; 2023 Nov 16. PMID: 37974546.
- Estimating Surveillance Bias in Child Maltreatment Reporting During Home Visiting Program Involvement.Holland ML, Esserman D, Taylor RM, Flaherty S, Leventhal JM. Child Maltreat. 2024 Feb; 2022 Sep 2. PMID: 36054017.
- Group sequential two-stage preference designs.Liu R, Li F, Esserman D, Ryan MM. Stat Med. 2024 Jan 30; 2023 Nov 27. PMID: 38010193.
- FZKA reverses gefitinib resistance by regulating EZH2/Snail/EGFR signaling pathway in lung adenocarcinoma.Tang Q, Xu M, Long S, Yu Y, Ma C, Wang R, Li J, Wang X, Fang F, Han L, Wu W, Wang S. J Ethnopharmacol. 2024 Jan 10; 2023 Jun 1. PMID: 37269912.
- (-)-α-Bisabolol inhibits D-Gal-induced HSF cellular senescence in vitro and prevents skin aging in vivo by reducing SASP.He M, Zhou P, Chen H, Zhang J, Zhang Y, Zheng X, Zhu W, Han L. Iran J Basic Med Sci. 2024. PMID: 39055870.
2023
- Evaluation of prognostic significance of lymphovascular space invasion in early stage endometrial cancer: a systematic review and meta-analysis.Qin ZJ, Wang YS, Chen YL, Zheng A, Han L. Front Oncol. 2023; 2024 Jan 11. PMID: 38273843.
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