William Asch, MD/PhD, BA
Associate Professor of Medicine (Nephrology); Program Director, Transplant Nephrology Fellowship Program, Internal Medicine; Director of Pre-Transplant Operations, Internal Medicine
Research & Publications
Biography
News
Locations
Coauthors
Selected Publications
- Blood Transcriptomes of SARS-CoV-2–Infected Kidney Transplant Recipients Associated with Immune Insufficiency Proportionate to SeveritySun Z, Zhang Z, Banu K, Azzi YA, Reghuvaran A, Fredericks S, Planoutene M, Hartzell S, Kim Y, Pell J, Tietjen G, Asch W, Kulkarni S, Formica R, Rana M, Maltzman JS, Zhang W, Akalin E, Heeger PS, Cravedi P, Menon MC. Blood Transcriptomes of SARS-CoV-2–Infected Kidney Transplant Recipients Associated with Immune Insufficiency Proportionate to Severity. Journal Of The American Society Of Nephrology 2022, 33: 2108-2122. PMID: 36041788, PMCID: PMC9678030, DOI: 10.1681/asn.2022010125.
- Is Prioritization of Kidney Allografts to Combined Liver-Kidney Recipients Appropriate? COMMENTARYAsch WS. Is Prioritization of Kidney Allografts to Combined Liver-Kidney Recipients Appropriate? COMMENTARY. Kidney360 2022, 3: 999-1002. PMID: 35849645, PMCID: PMC9255872, DOI: 10.34067/kid.0005042021.
- Evaluating the Impact and Rationale of Race-Specific Estimations of Kidney Function: Estimations from U.S. NHANES, 2015-2018Tsai JW, Cerdeña JP, Goedel WC, Asch WS, Grubbs V, Mendu ML, Kaufman JS. Evaluating the Impact and Rationale of Race-Specific Estimations of Kidney Function: Estimations from U.S. NHANES, 2015-2018. EClinicalMedicine 2021, 42: 101197. PMID: 34849475, PMCID: PMC8608882, DOI: 10.1016/j.eclinm.2021.101197.
- Genetic and Epidemiologic Analyses of an Outbreak of Pneumocystis jirovecii Pneumonia Among Kidney Transplant Recipients in the United States.Azar MM, Cohen E, Ma L, Cissé OH, Gan G, Deng Y, Belfield K, Asch W, Grant M, Gleeson S, Koff A, Gaston DC, Topal J, Curran S, Kulkarni S, Kovacs JA, Malinis M. Genetic and Epidemiologic Analyses of an Outbreak of Pneumocystis jirovecii Pneumonia Among Kidney Transplant Recipients in the United States. Clinical Infectious Diseases 2021, 74: 639-647. PMID: 34017984, PMCID: PMC9012955, DOI: 10.1093/cid/ciab474.
- Impact of Low-Dose Fluconazole on Tacrolimus Dosing in Renal TransplantJohnston JP, Cohen EA, Casal GH, Asch WS, Reardon DP. Impact of Low-Dose Fluconazole on Tacrolimus Dosing in Renal Transplant. Journal Of Pharmacy Practice 2021, 35: 701-706. PMID: 33759619, DOI: 10.1177/08971900211000702.
- Is prioritization of kidney allografts to combined liver-kidney recipients appropriate? Discussion of the Pros and Cons.Asch WS. Is prioritization of kidney allografts to combined liver-kidney recipients appropriate? Discussion of the Pros and Cons. Kidney360, In Press, 2021
- Identifying a Kidney Transplant Recipient COVID Phenotype to Aid Test Utilization in the Setting of Limited Testing Availability—Does One Exist?Virmani S, Gleeson SE, Girone GF, Malhotra D, Cohen EA, Klarman SE, Asch WS. Identifying a Kidney Transplant Recipient COVID Phenotype to Aid Test Utilization in the Setting of Limited Testing Availability—Does One Exist? Transplantation Proceedings 2020, 52: 2584-2591. PMID: 32711848, PMCID: PMC7305913, DOI: 10.1016/j.transproceed.2020.05.033.
- Clinical Implications of Unique Drug Interaction Between Extended Release Tacrolimus and PhenytoinHarkness TM, Cohen EA, Asch WS, Belfield KD. Clinical Implications of Unique Drug Interaction Between Extended Release Tacrolimus and Phenytoin. Progress In Transplantation 2020, 30: 177-178. PMID: 32233829, DOI: 10.1177/1526924820913500.
- The Role of the General Nephrologist in Evaluating Patients for Kidney Transplantation: Core Curriculum 2020Virmani S, Asch WS. The Role of the General Nephrologist in Evaluating Patients for Kidney Transplantation: Core Curriculum 2020. American Journal Of Kidney Diseases 2020, 76: 567-579. PMID: 32199707, DOI: 10.1053/j.ajkd.2020.01.001.
- Is Hypertension Following Donor Nephrectomy Cause For Elevated Living Donor Kidney Function Concern?Asch WS. Is Hypertension Following Donor Nephrectomy Cause For Elevated Living Donor Kidney Function Concern? Clinical Journal Of The American Society Of Nephrology 2019, 14: 1427-1429. PMID: 31591256, PMCID: PMC6777590, DOI: 10.2215/cjn.09650819.
- Graft-Versus-Host Disease After Pancreatic TransplantationSaffo S, Peng C, Kibbi N, Patel N, Robert ME, Adekolu E, Asch WS, Sanchez M. Graft-Versus-Host Disease After Pancreatic Transplantation. ACG Case Reports Journal 2019, 6: e00214. PMID: 31750381, PMCID: PMC6831153, DOI: 10.14309/crj.0000000000000214.
- New England BK consortium: Regional survey of BK screening and management protocols in comparison to published consensus guidelinesGabardi S, Pavlakis M, Tan C, Francis J, Cardarelli F, Asch W, Bodziak K, Chobanian M, Gilligan H, Gohh R, Kung S, Inker L, Martin S, Rodig N, Rossi A, Chandraker A. New England BK consortium: Regional survey of BK screening and management protocols in comparison to published consensus guidelines. Transplant Infectious Disease 2018, 20: e12985. PMID: 30175491, DOI: 10.1111/tid.12985.
- Frailty and Perioperative OutcomesDeshpande R, Asch W, Malinis M. Frailty and Perioperative Outcomes. Current Anesthesiology Reports 2018, 8: 225-231. DOI: 10.1007/s40140-018-0275-4.
- Delayed Graft Function Phenotypes and 12-Month Kidney Transplant OutcomesHall IE, Reese PP, Doshi MD, Weng FL, Schröppel B, Asch WS, Ficek J, Thiessen-Philbrook H, Parikh CR. Delayed Graft Function Phenotypes and 12-Month Kidney Transplant Outcomes. Transplantation 2017, 101: 1913-1923. PMID: 27495761, PMCID: PMC5292094, DOI: 10.1097/tp.0000000000001409.
- National Kidney Allocation SystemAsch W, Stewart D, Formica R. National Kidney Allocation System. DeckerMed Nephrology Dialysis And Transplantation 2017 DOI: 10.2310/nephro.12068.
- Kidney Transplantation24. Nemr, Saed, and Asch, WS. "Kidney Transplantation." In: CURRENT Diagnosis & Treatment: Nephrology & Hypertension, 2e Eds. Edgar V. Lerma, et al. New York, NY: McGraw-Hill. 2017
- New Organ Allocation System for Combined Liver-Kidney Transplants and the Availability of Kidneys for Transplant to Patients with Stage 4–5 CKDAsch WS, Bia MJ. New Organ Allocation System for Combined Liver-Kidney Transplants and the Availability of Kidneys for Transplant to Patients with Stage 4–5 CKD. Clinical Journal Of The American Society Of Nephrology 2016, 12: 848-852. PMID: 28028050, PMCID: PMC5477211, DOI: 10.2215/cjn.08480816.
- Belatacept and Eculizumab for Treatment of Calcineurin Inhibitor-induced Thrombotic Microangiopathy After Kidney Transplantation: Case ReportMerola J, Yoo PS, Schaub J, Smith JD, Rodriguez-Davalos MI, Tichy E, Mulligan DC, Asch W, Formica R, Kashgarian M, Kulkarni S. Belatacept and Eculizumab for Treatment of Calcineurin Inhibitor-induced Thrombotic Microangiopathy After Kidney Transplantation: Case Report. Transplantation Proceedings 2016, 48: 3106-3108. PMID: 27932157, DOI: 10.1016/j.transproceed.2016.04.005.
- Cancer and Mortality in Solid-Organ Transplantation: Preventable or Inevitable?Asch WS, Perazella MA. Cancer and Mortality in Solid-Organ Transplantation: Preventable or Inevitable? American Journal Of Kidney Diseases 2016, 68: 839-842. PMID: 27405594, DOI: 10.1053/j.ajkd.2016.06.009.
- Ambulatory Blood Pressure in Patients with Chronic Kidney DiseaseAsch W, Santos S, Peixoto A. Ambulatory Blood Pressure in Patients with Chronic Kidney Disease. 2016, 277-298. DOI: 10.1007/978-3-319-22771-9_14.
- Duration of Prophylaxis against Fungal Infection in Kidney Transplant RecipientsGuerra CM, Formica RN, Kulkarni S, Asch WS, Tichy EM. Duration of Prophylaxis against Fungal Infection in Kidney Transplant Recipients. Progress In Transplantation 2015, 25: 311-315. PMID: 26645924, DOI: 10.7182/pit2015929.
- Revision of immunosuppression in a solid organ transplant recipient leads to complete remission of metastatic undifferentiated carcinomaWaldman AH, McNiff JM, Liapakis A, Asch WS, Smith-Marrone S, Colegio OR. Revision of immunosuppression in a solid organ transplant recipient leads to complete remission of metastatic undifferentiated carcinoma. JAAD Case Reports 2015, 1: s8-s11. PMID: 27051810, PMCID: PMC4809581, DOI: 10.1016/j.jdcr.2015.09.010.
- Hyperuricemia and gout in solid-organ transplant: update in pharmacological management.Sullivan PM, William A, Tichy EM. Hyperuricemia and gout in solid-organ transplant: update in pharmacological management. Progress In Transplantation (Aliso Viejo, Calif.) 2015, 25: 263-70. PMID: 26308787, DOI: 10.7182/pit2015322.
- Renal cancer in kidney transplanted patientsFrascà GM, Sandrini S, Cosmai L, Porta C, Asch W, Santoni M, Salviani C, D’Errico A, Malvi D, Balestra E, Gallieni M. Renal cancer in kidney transplanted patients. Journal Of Nephrology 2015, 28: 659-668. PMID: 26202137, DOI: 10.1007/s40620-015-0219-8.
- Ambulatory blood pressure in patients with chronic kidney disease.21. Asch WS, Santos SFF, Peixoto AJ. Ambulatory blood pressure in patients with chronic kidney disease. In Blood Pressure Monitoring in Cardiovascular Medicine and Therapeutics, Clinical Hypertension and Vascular Diseases. Ed. William B. White. Humana Press Inc., New York, NY. 2015.
- Oncologic Issues and Kidney Transplantation: A Review of Frequency, Mortality, and ScreeningAsch WS, Bia MJ. Oncologic Issues and Kidney Transplantation: A Review of Frequency, Mortality, and Screening. Advances In Kidney Disease And Health 2014, 21: 106-113. PMID: 24359993, DOI: 10.1053/j.ackd.2013.07.003.
- A One-Day Centralized Work-up for Kidney Transplant Recipient Candidates: A Quality Improvement ReportFormica RN, Barrantes F, Asch WS, Bia MJ, Coca S, Kalyesubula R, McCloskey B, Leary T, Arvelakis A, Kulkarni S. A One-Day Centralized Work-up for Kidney Transplant Recipient Candidates: A Quality Improvement Report. American Journal Of Kidney Diseases 2012, 60: 288-294. PMID: 22571868, DOI: 10.1053/j.ajkd.2012.04.008.
- Patient Education to Reduce Disparities in Renal TransplantationAsch WS, Bia MJ. Patient Education to Reduce Disparities in Renal Transplantation. Clinical Journal Of The American Society Of Nephrology 2012, 7: 527-529. PMID: 22403275, DOI: 10.2215/cjn.01770212.
- When should nephrectomy be performed for a failed renal transplant?Asch WS, Bia M. When should nephrectomy be performed for a failed renal transplant? Seminars In Dialysis 2011, 24: 374-376. PMID: 21801221, DOI: 10.1111/j.1525-139x.2011.00903.x.
- Should Living Kidney Donor Candidates with Impaired Fasting Glucose Donate?Vigneault CB, Asch WS, Dahl NK, Bia MJ. Should Living Kidney Donor Candidates with Impaired Fasting Glucose Donate? Clinical Journal Of The American Society Of Nephrology 2011, 6: 2054-2059. PMID: 21784837, DOI: 10.2215/cjn.03370411.
- Combined Liver Kidney Transplantation: Critical Analysis of a Single-Center ExperienceCimsit B, Schilsky M, Moini M, Cartiera K, Arvelakis A, Kulkarni S, Formica R, Caldwell C, Taddei T, Asch W, Emre S. Combined Liver Kidney Transplantation: Critical Analysis of a Single-Center Experience. Transplantation Proceedings 2011, 43: 901-904. PMID: 21486624, DOI: 10.1016/j.transproceed.2011.02.033.
- Multidetector CT angiography in living donor renal transplantation: accuracy and discrepancies in right venous anatomyKulkarni S, Emre S, Arvelakis A, Asch W, Bia M, Formica R, Israel G. Multidetector CT angiography in living donor renal transplantation: accuracy and discrepancies in right venous anatomy. Clinical Transplantation 2011, 25: 77-82. PMID: 20070320, DOI: 10.1111/j.1399-0012.2009.01193.x.
- A CENTER COORDINATED, PRE-TRANSPLANT EVALUATION ELIMINATES BARRIERS TO KIDNEY TRANSPLANTATION AND ESTABLISHES PARITY ACROSS ALL SOCIO-ECONOMIC GROUPSBarrantes F, Arvelakis A, Asch W, Coca S, Kalyesubula R, Bia M, Formica R, Kulkarni S. A CENTER COORDINATED, PRE-TRANSPLANT EVALUATION ELIMINATES BARRIERS TO KIDNEY TRANSPLANTATION AND ESTABLISHES PARITY ACROSS ALL SOCIO-ECONOMIC GROUPS. Transplantation 2010, 90: 249. DOI: 10.1097/00007890-201007272-00471.
- 45: Single-Day Work-Up Protocol Is Associated With a Shorter Time to Kidney Transplant: The Yale-New Haven Transplantation Center ExperienceBarrantes F, Kalyesubula R, A A, Lettieri D, Asch W, Bia M, Formica R, Kulkarni S. 45: Single-Day Work-Up Protocol Is Associated With a Shorter Time to Kidney Transplant: The Yale-New Haven Transplantation Center Experience. American Journal Of Kidney Diseases 2010, 55: b43. DOI: 10.1053/j.ajkd.2010.02.052.
- Kidney Transplantation and HIV: Does Recipient Privacy Outweigh the Donor's Right to Information?Formica RN, Asch WS, Wagner KR, Kulkarni S. Kidney Transplantation and HIV: Does Recipient Privacy Outweigh the Donor's Right to Information? Clinical Journal Of The American Society Of Nephrology 2010, 5: 924-928. PMID: 20203162, PMCID: PMC2863980, DOI: 10.2215/cjn.06820909.
- Chapter 14 Molecular Genetics of Magnesium HomeostasisAsch W, Lifton R. Chapter 14 Molecular Genetics of Magnesium Homeostasis. 2009, 249-261. DOI: 10.1016/b978-0-12-449851-8.00014-0.
- Molecular genetics of magnesium homeostasis.Asch, W.S. and Lifton R.P. Molecular genetics of magnesium homeostasis. In Genetic Diseases of the Kidney Eds. R.P Lifton, S. Somlo, G. Giebisch, & D. Seldin. Elsevier/Academic Press, San Diego, CA. 2009 pp. 249-261
- Plasticin, a Type III Neuronal Intermediate Filament Protein, Assembles as an Obligate HeteropolymerAsch WS, Schechter N. Plasticin, a Type III Neuronal Intermediate Filament Protein, Assembles as an Obligate Heteropolymer. Journal Of Neurochemistry 2000, 75: 1475-1486. PMID: 10987827, DOI: 10.1046/j.1471-4159.2000.0751475.x.
- Gefiltin in zebrafish embryos: sequential gene expression of two neurofilament proteins in retinal ganglion cellsLeake D, Asch W, Canger A, Schechter N. Gefiltin in zebrafish embryos: sequential gene expression of two neurofilament proteins in retinal ganglion cells. Differentiation 1999, 65: 181-189. PMID: 10653354, DOI: 10.1046/j.1432-0436.1999.6540181.x.
- Restricted expression of the neuronal intermediate filament protein plasticin during zebrafish developmentCanger A, Passini M, Asch W, Leake D, Zafonte B, Glasgow E, Schechter N. Restricted expression of the neuronal intermediate filament protein plasticin during zebrafish development. The Journal Of Comparative Neurology 1998, 399: 561-572. PMID: 9741483, DOI: 10.1002/(sici)1096-9861(19981005)399:4<561::aid-cne8>3.0.co;2-#.
- Cloning of Zebrafish Neurofilament cDNAs for Plasticin and Gefiltin: Increased mRNA Expression in Ganglion Cells After Optic Nerve InjuryAsch W, Leake D, Canger A, Passini M, Argenton F, Schechter N. Cloning of Zebrafish Neurofilament cDNAs for Plasticin and Gefiltin: Increased mRNA Expression in Ganglion Cells After Optic Nerve Injury. Journal Of Neurochemistry 1998, 71: 20-32. PMID: 9648847, DOI: 10.1046/j.1471-4159.1998.71010020.x.
- Cloning of zebrafish vsx1: Expression of a paired‐like homeobox gene during CNS developmentPassini M, Kurtzman A, Canger A, Asch W, Wray G, Raymond P, Schechter N. Cloning of zebrafish vsx1: Expression of a paired‐like homeobox gene during CNS development. Genesis 1998, 23: 128-141. PMID: 9770270, DOI: 10.1002/(sici)1520-6408(1998)23:2<128::aid-dvg5>3.0.co;2-8.