1996
Randomized comparison of ligation versus ligation plus sclerotherapy in patients with bleeding esophageal varices
Laine L, Stein C, Sharma V. Randomized comparison of ligation versus ligation plus sclerotherapy in patients with bleeding esophageal varices. Gastroenterology 1996, 110: 529-533. PMID: 8566601, DOI: 10.1053/gast.1996.v110.pm8566601.Peer-Reviewed Original ResearchConceptsEsophageal varicesVariceal eradicationCombined therapyTreatment sessionsMajor bleedingMean followEndoscopic sclerotherapyHospital daysRepeat endoscopyRandomized comparisonSclerotherapyVaricesPatientsAbstractTextTherapyMore sessionsLigationEradicationComplicationsSignificant differencesAIMSTreatmentSessionsGreater timeBleeding
1995
Endoscopic ligation compared with sclerotherapy for treatment of esophageal variceal bleeding. A meta-analysis.
Laine L, Cook D. Endoscopic ligation compared with sclerotherapy for treatment of esophageal variceal bleeding. A meta-analysis. Annals Of Internal Medicine 1995, 123: 280-7. PMID: 7611595, DOI: 10.7326/0003-4819-123-4-199508150-00007.Peer-Reviewed Original ResearchConceptsEsophageal variceal bleedingTreatment of patientsEndoscopic ligationVariceal bleedingEsophageal varicesEndoscopic treatmentDuplicate data abstractionDuplicate independent reviewEndoscopic treatment sessionsRate of deathRelevant primary articlesReview of citationsVariceal obliterationBacterial peritonitisLigation therapyPulmonary infectionEsophageal strictureMethodologic qualitySclerotherapyMortality rateTreatment sessionsPatientsRelevant articlesPrimary investigatorUnpublished studies
1993
Endoscopic ligation compared with sclerotherapy for the treatment of bleeding esophageal varices.
Laine L, el-Newihi HM, Migikovsky B, Sloane R, Garcia F. Endoscopic ligation compared with sclerotherapy for the treatment of bleeding esophageal varices. Annals Of Internal Medicine 1993, 119: 1-7. PMID: 8498757, DOI: 10.7326/0003-4819-119-1-199307010-00001.Peer-Reviewed Original ResearchConceptsRisk of deathEsophageal varicesVariceal eradicationEndoscopic examinationLigation groupInitial endoscopic examinationUrban county hospitalKaplan-Meier estimatesLigation treatmentTransfusion requirementsVariceal obliterationFurther bleedingHospital stayEndoscopic sclerotherapyEndoscopic therapyEsophageal ulcerLocal complicationsRecurrent varicesBlood transfusionSevere bleedingEndoscopic ligationTreatment failureEsophageal strictureCounty HospitalSclerotherapy
1992
Indications, Technique, and Complications of Balloon Tamponade for Variceal Gastrointestinal Bleeding
Cook D, Laine L. Indications, Technique, and Complications of Balloon Tamponade for Variceal Gastrointestinal Bleeding. Journal Of Intensive Care Medicine 1992, 7: 212-218. PMID: 10147943, DOI: 10.1177/088506669200700408.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsBalloon tamponadeAcute upper gastrointestinal haemorrhageVariceal gastrointestinal bleedingUpper gastrointestinal hemorrhageBalloon insertionGastrointestinal bleedingGastrointestinal hemorrhageEsophageal varicesPotential complicationsTherapeutic endoscopyTimely treatmentTamponadeComplicationsVaricesBleedingSclerotherapyHemorrhagePatientsEndoscopyHemostatis