Professor of Medicine (Digestive Diseases)
Research Interests
- Colitis, Ulcerative
- Crohn Disease
- Genetics
- Immune System
- Immunity, Innate
- Inflammation
- Intestines
- Molecular Biology
- T-Lymphocytes
- Inflammatory Bowel Diseases
Research
Research is one of the cornerstones of our work. Each year, we receive millions of dollars in funding from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDKK) to support our work. Our faculty members are engaged in a wide range of both basic laboratory research activities and patient-oriented clinical research.
On this page
Major areas of clinical research
- complications and treatment of cirrhosis, viral hepatitis, liver cancer, and IBD
- motility disorders of the esophagus, optimal application of advanced endoscopic techniques to clinical problems, including gastrointestinal bleeding, graft-versus-host disease, and pancreatic biliary disorders
- advanced endoscopic techniques, pancreatitis, sphincter of oddi dysfunction, and other clinical aspects of biliary and pancreatic disease
- endoscopic outcomes research
Major areas of laboratory research
- regulation of bile secretion by the liver, including liver cell biology
- basis for portal hypertension, variceal bleeding, and other complications of cirrhosis
- mechanisms responsible for pancreatic inflammation and pancreatitis genetics and immunobiology of inflammatory bowel disease
- liver growth, cancer, and stem cells
- bile ductular secretion
- immunology of the healthy and diseased liver
- metabolic liver diseases
- colon physiology and mechanisms of diarrhea
Related programs
- the Yale Liver Center, an NIH-funded facility that supports both basic and clinical research in liver diseases
- the Yale IBD Program, which is home to the NIH/NIDDK IBD Genetics Consortium
- the Yale Center for Clinical Investigation, an NIH-funded facility that supports investigations and novel treatment protocols in patients.
Research Faculty
Professor of Medicine (Digestive Diseases); Director of Endoscopic Ultrasound, Digestive Diseases; Associate Director, Endoscopy; Director, Yale Advanced Endoscopy Fellowship, Digestive Diseases
Research Interests- Barrett Esophagus
- Biliary Tract Diseases
- Biliary Tract Neoplasms
- Cholangiopancreatography, Endoscopic Retrograde
- Cholelithiasis
- Colonic Polyps
- Digestive System Diseases
- Digestive System Neoplasms
- Duodenal Neoplasms
- Endoscopy
- Esophageal Achalasia
- Esophageal Neoplasms
- Gallbladder Diseases
- Gastrointestinal Diseases
- Gastrointestinal Neoplasms
- Gastrointestinal Hemorrhage
- Pancreas
- Pancreatic Cyst
- Pancreatic Diseases
- Pancreatic Neoplasms
- Pancreatitis
- Stomach Neoplasms
- Colorectal Neoplasms
- Zenker Diverticulum
- Gastrointestinal Stromal Tumors
- Endoscopic Ultrasound-Guided Fine Needle Aspiration
- Diseases
Associate Professor of Medicine (Digestive Diseases); Director, Fellowship Program, Digestive Diseases
Research Interests- Autoimmune Diseases
- Cystic Fibrosis
- Hepatitis
- Liver
- Liver Diseases
Professor Emeritus of Medicine (Digestive Diseases)
Research Interests- Adenosine Triphosphatases
- Digestive System Diseases
- Epithelial Cells
- Fatty Acids, Volatile
- Ion Transport
Ensign Professor of Medicine (Digestive Diseases); Emeritus Director, Yale Liver Center
Research Interests- Bile
- Cholestasis
- Digestive System Diseases
- Jaundice
- Liver
- Organoids
- Cholangitis, Sclerosing
Associate Professor of Radiology and Biomedical Imaging; Associate Professor , Digestive Diseases; Associate Professor , Biomedical Engineering; Principal Investigator, Yale Interventional Oncology Laboratory , Radiology & Biomedical Imaging; Director, Center for Minimally Invasive Therapies, Radiology & Biomedical Imaging; Associate Director, Clinical and Translational Core, Liver Center
Research Interests- Artificial Intelligence
- Carcinoid Tumor
- Carcinoma, Hepatocellular
- Image Processing, Computer-Assisted
- Liver
- Liver Cirrhosis
- Magnetic Resonance Imaging
- Metabolism
- Neoplasm Staging
- Chemotherapy, Cancer, Regional Perfusion
- Ablation Techniques
- Molecular Imaging
Professor of Medicine (Digestive Diseases)
Research Interests- Acetaminophen
- Fibrosis
- Liver Cirrhosis
- Chemical and Drug Induced Liver Injury
- Non-alcoholic Fatty Liver Disease
Assistant Professor of Medicine (Digestive Diseases) and of Pathology; Associate Director, Cellular & Molecular Physiology Core
Associate Professor of Medicine (Digestive Diseases); Director of Clinical Research, Yale Inflammatory Bowel Disease Program; Vice Chief of Clinical Research, Digestive Diseases
Professor of Medicine (Digestive Diseases)
Research Interests- Ascites
- Hepatorenal Syndrome
- Liver
- Liver Cirrhosis
- Liver Diseases
- Veterans
Henry J. and Joan W. Binder Professor of Medicine (Digestive Diseases) and of Cell Biology; Director Investigated Gastroenterology NIH T32, Internal Medicine; Deputy Director, MD-PhD Program
Research Interests- Autophagy
- Cell Survival
- Cell Biology
- Digestive System Diseases
- Gastrointestinal Diseases
- Pancreatic Diseases
- Pancreatic Neoplasms
- Pancreatitis
- Pancreas, Exocrine
- Proteolysis
Assistant Professor of Internal Medicine (Digestive Diseases); Associate Fellowship Program Director, Digestive Diseases; Gastroenterology Elective Director - YNHH, Digestive Diseases
Research Interests- Gastrointestinal Hemorrhage
- Peptic Ulcer Hemorrhage
- Endoscopy, Gastrointestinal
- Helicobacter pylori
- Quality Improvement
Professor of Medicine (Digestive Diseases)
Research Interests- Fibrosis
- Hypertension, Portal
- Kupffer Cells
- Liver Regeneration
- Pancreatitis
- Splenomegaly
- Vascular Diseases
- Lymphangiogenesis
- Endothelial Cells
Professor of Medicine (Digestive Diseases)
Research Interests- Biliary Tract Diseases
- Sphincter of Oddi
- Pancreas
Associate Professor of Medicine (Digestive Diseases); Chief of Endoscopy, Gastroenterology
Professor of Medicine (Digestive Diseases); Chief, Section of Digestive Diseases, Internal Medicine; Medical Chief, Digestive Health; Chief, Section of Digestive Diseases
Assistant Professor of Medicine (Digestive Diseases); Associate Program Director, Gastroenterology Fellowship, Bridgeport Hospital
Assistant Professor of Medicine (Digestive Diseases); Director of Inflammatory Bowel Disease Fellowship Program, Digestive Diseases
Professor of Medicine; Director, Clinical Hepatology, Digestive Diseases; Vice-Chief of Hepatology, Section of Digestive Diseases, Digestive Diseases; Director, Yale Viral Hepatitis Program
Research Interests- Delivery of Health Care
- Hepatitis D
- Fatty Liver
- Health Services Research
- Hepatitis B
- Hepatitis C
- Carcinoma, Hepatocellular
- Liver Cirrhosis
- Liver Neoplasms
- Quality of Health Care
- Clinical Trial