Using phosphatidylethanol as an adjunct to self-reported alcohol use improves identification of liver fibrosis risk.
Murnane P, Afshar M, Chamie G, Cook R, Ferguson T, Haque L, Jacobson K, Justice A, Kim T, Khalili M, Krupitsky E, McGinnis K, Molina P, Muyindike W, Myers B, Richards V, So-Armah K, Stewart S, Sulkowski M, Tien P, Hahn J. Using phosphatidylethanol as an adjunct to self-reported alcohol use improves identification of liver fibrosis risk. The American Journal Of Gastroenterology 2024 PMID: 39480054, DOI: 10.14309/ajg.0000000000003178.Peer-Reviewed Original ResearchLiver fibrosis riskAUDIT-CFIB-4Self-reported alcohol useOdds ratioAlcohol useFibrosis riskPooled individual-level dataLiver fibrosis preventionBody mass indexAssessment of alcohol useManagement of liver diseaseOne-unit differenceIndividual-level dataMedian ageAUDIT-C.Mass indexSuppression statusLiver diseaseFibrosis preventionBlood concentrationsAdjusted modelsLogistic regressionCategorical variablesHIVIntegrated and collaborative care across the spectrum of alcohol-associated liver disease and alcohol use disorder.
Haque L, Leggio L. Integrated and collaborative care across the spectrum of alcohol-associated liver disease and alcohol use disorder. Hepatology 2024 PMID: 38935926, DOI: 10.1097/hep.0000000000000996.Peer-Reviewed Original ResearchAUD careAlcohol-associated liver diseaseAlcohol use disorderCollaborative careImpact of health disparitiesAlcohol-related deathsImpact of comorbid conditionsPublic health impactUse disorderHarm reduction approachesLiver diseaseInterprofessional teamHealth disparitiesTreatment of alcohol use disordersComprehensive careProblematic alcohol useSubstance use disordersSpectrum of alcohol-associated liver diseasesTreatment gapLiver-related outcomesMinority of patientsLiver-related morbidityAlcohol use disorder treatmentCareAlcohol useTreatment of alcohol use disorder in patients with alcohol-associated liver disease: Innovative approaches and a call to action
Haque L, Zuluaga P, Muga R, Fuster D. Treatment of alcohol use disorder in patients with alcohol-associated liver disease: Innovative approaches and a call to action. Addiction Science & Clinical Practice 2024, 19: 19. PMID: 38504384, PMCID: PMC10949674, DOI: 10.1186/s13722-024-00448-8.Peer-Reviewed Original ResearchConceptsAlcohol-associated liver diseaseAlcohol use disorderLiver diseasePresence of liver cirrhosisTreatment of alcohol use disordersUse disorderInnovative treatment strategiesUnhealthy alcohol usePharmacologic treatment choicesTreating unhealthy alcohol useLiver transplantationLiver cirrhosisTreatment strategiesTreatment choiceEfficacious treatmentLiver deathsPatientsAlcohol useDiseaseLiverTreatmentDisordersCirrhosisTransplantation