1998
CFTR: From scientific inquiry to clinical remedy
Gorelick F. CFTR: From scientific inquiry to clinical remedy. Gastroenterology 1998, 115: 5. PMID: 9649449, DOI: 10.1016/s0016-5085(98)70355-5.Peer-Reviewed Original ResearchCystic Fibrosis Transmembrane Conductance RegulatorHumansCellular Localization of Calmodulin-dependent Protein Kinases I and II to A-cells and D-cells of the Endocrine Pancreas
Matovcik L, Nairn A, Gorelick F. Cellular Localization of Calmodulin-dependent Protein Kinases I and II to A-cells and D-cells of the Endocrine Pancreas. Journal Of Histochemistry & Cytochemistry 1998, 46: 519-526. PMID: 9524198, DOI: 10.1177/002215549804600412.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCalcium-Calmodulin-Dependent Protein Kinase Type 1Calcium-Calmodulin-Dependent Protein Kinase Type 2Calcium-Calmodulin-Dependent Protein KinasesCyclic AMP Response Element-Binding ProteinCystic Fibrosis Transmembrane Conductance RegulatorDigestive SystemFluorescent Antibody Technique, IndirectGlucagonImmunoblottingIslets of LangerhansMicroscopy, ConfocalPancreasRatsSomatostatinSomatostatin-Secreting CellsTissue DistributionConceptsCaM kinase IKinase IProtein kinase ICaM kinase IIGlucagon secretionKinase IICalmodulin-dependent protein kinase ISomatostatin cellsDependent protein kinase IA cellsSomatostatin-containing D-cellsD cellsDifferent cell typesRegulation of Ca2Islets of LangerhansCaM kinaseCytosolic proteinsI antibodiesSomatostatin granulesPancreatic polypeptideCellular localizationRegulatory rolePeptide antibodiesIntracellular Ca2Endocrine pancreas
1995
Effect of cerulein hyperstimulation on the paracellular barrier of rat exocrine pancreas
Fallon M, Gorelick F, Anderson J, Mennone A, Saluja A, Steer M. Effect of cerulein hyperstimulation on the paracellular barrier of rat exocrine pancreas. Gastroenterology 1995, 108: 1863-1872. PMID: 7539388, DOI: 10.1016/0016-5085(95)90151-5.Peer-Reviewed Original ResearchActinsAmino Acid SequenceAnimalsCalciumCeruletideCystic Fibrosis Transmembrane Conductance RegulatorHorseradish PeroxidaseMaleMembrane ProteinsMolecular Sequence DataPancreasPermeabilityRatsRats, Wistar
1992
Scientific advances in cystic fibrosis
Marino C, Gorelick F. Scientific advances in cystic fibrosis. Gastroenterology 1992, 103: 681-693. PMID: 1378805, DOI: 10.1016/0016-5085(92)90866-w.Peer-Reviewed Original ResearchChloride ChannelsCloning, MolecularCystic FibrosisCystic Fibrosis Transmembrane Conductance RegulatorExocrine Pancreatic InsufficiencyHumansMembrane Proteins
1991
Localization of the cystic fibrosis transmembrane conductance regulator in pancreas.
Marino CR, Matovcik LM, Gorelick FS, Cohn JA. Localization of the cystic fibrosis transmembrane conductance regulator in pancreas. Journal Of Clinical Investigation 1991, 88: 712-716. PMID: 1713921, PMCID: PMC295422, DOI: 10.1172/jci115358.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceChloridesCystic FibrosisCystic Fibrosis Transmembrane Conductance RegulatorHumansImmunoblottingImmunohistochemistryMembrane ProteinsMolecular Sequence DataPancreatic DuctsConceptsCF transmembrane conductance regulatorCystic fibrosisTransmembrane conductance regulatorCFTR peptidesPancreatic secretory functionDouble-label immunofluorescence studiesConductance regulatorDuct epithelial cellsCystic fibrosis transmembrane conductance regulatorFibrosis transmembrane conductance regulatorPancreatic insufficiencyIntralobular duct cellsSecretory functionHuman pancreasCFTR moleculesChloride transportMonoclonal antibodiesApical domainDuct cellsAntibodiesEpithelial cellsAcinar cellsCFTR proteinImmunofluorescence studiesProtein products