2024
A Multimodal Video-Based AI Biomarker for Aortic Stenosis Development and Progression
Oikonomou E, Holste G, Yuan N, Coppi A, McNamara R, Haynes N, Vora A, Velazquez E, Li F, Menon V, Kapadia S, Gill T, Nadkarni G, Krumholz H, Wang Z, Ouyang D, Khera R. A Multimodal Video-Based AI Biomarker for Aortic Stenosis Development and Progression. JAMA Cardiology 2024, 9: 534-544. PMID: 38581644, PMCID: PMC10999005, DOI: 10.1001/jamacardio.2024.0595.Peer-Reviewed Original ResearchCardiac magnetic resonanceAortic valve replacementCardiac magnetic resonance imagingAV VmaxSevere ASAortic stenosisCohort studyPeak aortic valve velocityCohort study of patientsAortic valve velocityCohort of patientsTraditional cardiovascular risk factorsAssociated with faster progressionStudy of patientsCedars-Sinai Medical CenterAssociated with AS developmentCardiovascular risk factorsCardiovascular imaging modalitiesIndependent of ageModerate ASEjection fractionEchocardiographic studiesValve replacementRisk stratificationCardiac structure
2017
Contemporary risk model for inhospital major bleeding for patients with acute myocardial infarction: The acute coronary treatment and intervention outcomes network (ACTION) registry®–Get With The Guidelines (GWTG)®
Desai NR, Kennedy KF, Cohen DJ, Connolly T, Diercks DB, Moscucci M, Ramee S, Spertus J, Wang TY, McNamara RL. Contemporary risk model for inhospital major bleeding for patients with acute myocardial infarction: The acute coronary treatment and intervention outcomes network (ACTION) registry®–Get With The Guidelines (GWTG)®. American Heart Journal 2017, 194: 16-24. PMID: 29223432, DOI: 10.1016/j.ahj.2017.08.004.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionIntervention Outcomes Network RegistryAcute Coronary TreatmentInhospital major bleedingMajor bleedingRisk scoreCoronary TreatmentValidation cohortMyocardial infarctionHigh riskLower riskContemporary risk modelsProspective risk stratificationSimplified risk scoreHospital quality assessmentRisk adjustment methodsBaseline hemoglobinCardiogenic shockCreatinine clearanceFrequent complicationDerivation cohortHeart failureRisk stratificationSignificant morbidityCardiac arrest