2007
Effect of acetylcholinesterase inhibition with pyridostigmine on cardiac parasympathetic function in sedentary adults and trained athletes
Dewland TA, Androne AS, Lee FA, Lampert RJ, Katz SD. Effect of acetylcholinesterase inhibition with pyridostigmine on cardiac parasympathetic function in sedentary adults and trained athletes. AJP Heart And Circulatory Physiology 2007, 293: h86-h92. PMID: 17322413, DOI: 10.1152/ajpheart.01339.2006.Peer-Reviewed Original ResearchConceptsHeart rate recoveryPostexercise heart rate recoveryCardiac parasympathetic functionCardiac parasympathetic toneHeart rate variabilityRate recoveryParasympathetic toneSedentary adultsFrequency domain indicesHeart rateParasympathetic functionRate variabilityParasympathetic regulationSingle oral doseCardiac parasympathetic regulationExercise trainingCrossover trialOral doseParasympathetic pathwaysSedentary subjectsPyridostigmineHuman studiesPlaceboEfferent signalsAcetylcholinesterase inhibitors
2003
Effects of propranolol on recovery of heart rate variability following acute myocardial infarction and relation to outcome in the Beta-Blocker Heart Attack Trial
Lampert R, Ickovics JR, Viscoli CJ, Horwitz RI, Lee FA. Effects of propranolol on recovery of heart rate variability following acute myocardial infarction and relation to outcome in the Beta-Blocker Heart Attack Trial. The American Journal Of Cardiology 2003, 91: 137-142. PMID: 12521623, DOI: 10.1016/s0002-9149(02)03098-9.Peer-Reviewed Original ResearchConceptsBeta-Blocker Heart Attack TrialAcute myocardial infarctionHeart rate variabilityPlacebo-treated patientsHeart Attack TrialMyocardial infarctionEffect of propranololBeta blockersAttack TrialDepressed heart rate variabilityRate variabilityRecovery of HRVLF/HF ratioPropranolol-treated patientsWeeks of treatmentHF ratioHigh-frequency powerPropranolol therapyPropranolol treatmentSympathetic predominanceAutonomic toneParasympathetic toneSympathovagal balanceImproved outcomesSudden death