2018
Actin and myosin II modulate differentiation of pluripotent stem cells
Boraas L, Pineda E, Ahsan T. Actin and myosin II modulate differentiation of pluripotent stem cells. PLOS ONE 2018, 13: e0195588. PMID: 29664925, PMCID: PMC5903644, DOI: 10.1371/journal.pone.0195588.Peer-Reviewed Original ResearchConceptsPluripotent stem cellsMesodermal lineagesActin polymerizationStem cellsActin-myosin molecular motorEmbryonic stem cellsCell-based therapiesGerm lineageCytoskeletal tensionEndodermal lineagesDifferentiation eventsEmbryoid bodiesLineagesSpontaneous differentiationIntracellular factorsModulates differentiationMolecular motorsEarly differentiationStem cell-based therapiesActin-myosin interactionCytoskeletonDifferentiationRegenerative medicineEndothelial cellsCells
2016
Cytoskeletal Expression and Remodeling in Pluripotent Stem Cells
Boraas L, Guidry J, Pineda E, Ahsan T. Cytoskeletal Expression and Remodeling in Pluripotent Stem Cells. PLOS ONE 2016, 11: e0145084. PMID: 26771179, PMCID: PMC4714815, DOI: 10.1371/journal.pone.0145084.Peer-Reviewed Original ResearchConceptsEmbryonic stem cellsInduced pluripotent stem cellsPluripotent stem cellsCytoskeletal proteinsStem cellsMouse embryonic stem cellsEmbryoid body modelIPSC samplesUndifferentiated pluripotent stem cellsSimilar gene expressionCell-based therapiesLamin ACytoskeletal networkEmbryonic fibroblastsCytoskeletal intermediate filamentsGene expressionParental phenotypesGene levelSmooth muscle cell actinSpontaneous differentiationCytoskeletal markersCell actinDifferentiation studiesCytoskeletal expressionIntermediate filaments