2021
Right Ventricular Fatty Infiltration With an Abnormal ECG
Odanovic N, Mojibian HR, Young LH. Right Ventricular Fatty Infiltration With an Abnormal ECG. JACC Case Reports 2021, 3: 314-318. PMID: 34317526, PMCID: PMC8310990, DOI: 10.1016/j.jaccas.2020.11.017.Peer-Reviewed Case Reports and Technical NotesFatty infiltrationCardiac magnetic resonance imagingArrhythmogenic right ventricular cardiomyopathyRight ventricular hypertrophyBenign clinical courseRight ventricular cardiomyopathyMiddle-aged womenMagnetic resonance imagingClinical courseVentricular hypertrophyVentricular thickeningRoutine electrocardiogramVentricular cardiomyopathyAbnormal ECGResonance imagingInfiltrationEchocardiogramPatientsCardiomyopathyHypertrophyElectrocardiogramWomen
2016
miR-182 Modulates Myocardial Hypertrophic Response Induced by Angiogenesis in Heart
Li N, Hwangbo C, Jaba IM, Zhang J, Papangeli I, Han J, Mikush N, Larrivée B, Eichmann A, Chun HJ, Young LH, Tirziu D. miR-182 Modulates Myocardial Hypertrophic Response Induced by Angiogenesis in Heart. Scientific Reports 2016, 6: 21228. PMID: 26888314, PMCID: PMC4758045, DOI: 10.1038/srep21228.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCardiomegalyEndotheliumMechanistic Target of Rapamycin Complex 1Membrane ProteinsMiceMice, KnockoutMicroRNAsMultiprotein ComplexesMyocytes, CardiacNeovascularization, PathologicNitric OxideNitric Oxide Synthase Type IIIProteinsProto-Oncogene Proteins c-aktRGS ProteinsTOR Serine-Threonine KinasesUp-RegulationConceptsHypertrophic responseMiR-182Myocardial hypertrophyEndothelial-cardiomyocyte crosstalkLV pressure overloadEndothelium-derived NOPlacental growth factorMyocardial hypertrophic responseDevelopment of hypertrophyDegradation of regulatorsMiR-182 targetsHemodynamic demandsPressure overloadPlGF expressionBlood supplyParacrine actionCardiomyocyte hypertrophyMyocardial angiogenesisCardiac angiogenesisTreatment inhibitsHypertrophyAKT/mTORC1 pathwaysNovel targetAkt/Growth factor