2019
Effects of Pulmonary Hypertension and Right Ventricular Function in Short and Long-Term Kidney Function
Naranjo M, Lo K, Mezue K, Rangaswami J. Effects of Pulmonary Hypertension and Right Ventricular Function in Short and Long-Term Kidney Function. Current Cardiology Reviews 2019, 15: 3-11. PMID: 30306876, PMCID: PMC6367698, DOI: 10.2174/1573403x14666181008154215.Peer-Reviewed Original ResearchConceptsEffects of pulmonary hypertensionPulmonary hypertensionKidney transplant outcomesPrognostic implicationsTransplant outcomesPrognostic implications of pulmonary hypertensionRenal diseaseKidney diseaseDefinition of pulmonary hypertensionRight ventricular functionProgression of kidney diseaseAcute kidney injuryProgression of CKDPost-LVAD implantationVentricular functionKidney injuryHemodynamic dysfunctionKidney functionTreatment strategiesHemodynamic effectsHypertensionPatho-physiological effectsInfluence treatmentLVAD implantationMultiple body systems
2017
Blood Pressure Variability Predicts Adverse Events and Cardiovascular Outcomes in Chronic Kidney Disease: A Post-Hoc Analysis of the SPRINT Trial
Mezue K, Goyal A, Pressman G, Horrow J, Rangaswami J. Blood Pressure Variability Predicts Adverse Events and Cardiovascular Outcomes in Chronic Kidney Disease: A Post-Hoc Analysis of the SPRINT Trial. American Journal Of Hypertension 2017, 31: 48-52. PMID: 28985328, DOI: 10.1093/ajh/hpx128.Peer-Reviewed Original ResearchConceptsChronic kidney diseaseAcute kidney injuryDiastolic blood pressureDBP CVVisit-to-visitCardiovascular outcomesBlood pressure variabilityAdverse eventsPrimary outcomeKidney diseaseBlood pressureAssociated with adverse cardiovascular outcomesVisit-to-visit blood pressure variabilityCox proportional hazards regressionTarget systolic blood pressureAdverse cardiovascular outcomesPressure variabilityProportional hazards regressionSystolic blood pressurePredicting adverse eventsPost hoc analysisVisit-to-visit DBP variabilityAntihypertensive therapyIndependent predictorsKidney injury