2023
Reduced Stress-Related Neural Network Activity Mediates the Effect of Alcohol on Cardiovascular Risk
Mezue K, Osborne M, Abohashem S, Zureigat H, Gharios C, Grewal S, Radfar A, Cardeiro A, Abbasi T, Choi K, Fayad Z, Smoller J, Rosovsky R, Shin L, Pitman R, Tawakol A. Reduced Stress-Related Neural Network Activity Mediates the Effect of Alcohol on Cardiovascular Risk. Journal Of The American College Of Cardiology 2023, 81: 2315-2325. PMID: 37316112, PMCID: PMC10333800, DOI: 10.1016/j.jacc.2023.04.015.Peer-Reviewed Original ResearchConceptsNeural network activityAlcohol consumptionMACE riskEffects of alcoholAssociated with lower MACE riskHealth behavior surveyMass General Brigham BiobankNetwork activityBrain networksLower MACE riskChronic stressMedian follow-upLight/moderate alcohol consumptionCardiovascular risk factorsAdverse cardiovascular eventsAssociated with larger decreasesBrain imagingPotential health detrimentCardiovascular eventsFollow-upBehavior SurveyCardiovascular riskRisk factorsCardiovascular diseaseMACE
2016
Nocturnal Non-dipping Blood Pressure Profile in Black Normotensives Is Associated with Cardiac Target Organ Damage.
Mezue K, Isiguzo G, Madu C, Nwuruku G, Rangaswami J, Baugh D, Madu E. Nocturnal Non-dipping Blood Pressure Profile in Black Normotensives Is Associated with Cardiac Target Organ Damage. Ethnicity & Disease 2016, 26: 279-84. PMID: 27440966, PMCID: PMC4948793, DOI: 10.18865/ed.26.3.279.Peer-Reviewed Original ResearchConceptsCardiac target organ damageTarget organ damageNon-dippersBlood pressure profileNocturnal blood pressureOrgan damageBlood pressureBlack normotensivesNon-dipping of blood pressureMass indexCardiovascular riskLeft atrial volume indexLeft ventricular mass indexCardiovascular end-organ damageIncreased relative wall thicknessAtrial volume indexAmbulatory blood pressure patternsNon-dipper groupVentricular mass indexNocturnal non-dippingNon-dipping profileNon-dipping patternPredictor of cardiovascular riskEnd-organ damageNon-dipping blood pressure profile