2011
Prognostic Importance of Early Worsening Renal Function After Initiation of Angiotensin-Converting Enzyme Inhibitor Therapy in Patients With Cardiac Dysfunction
Testani JM, Kimmel SE, Dries DL, Coca SG. Prognostic Importance of Early Worsening Renal Function After Initiation of Angiotensin-Converting Enzyme Inhibitor Therapy in Patients With Cardiac Dysfunction. Circulation Heart Failure 2011, 4: 685-691. PMID: 21903907, PMCID: PMC3248247, DOI: 10.1161/circheartfailure.111.963256.Peer-Reviewed Original ResearchConceptsGlomerular filtration rateRenal functionPrognostic significanceAngiotensin-Converting Enzyme Inhibitor TherapyACE-I therapySetting of angiotensinWorsening Renal FunctionEnzyme inhibitor therapyPrimary end pointAdverse prognostic significanceEnalapril groupEnalapril therapyPlacebo groupStudy drugVentricular dysfunctionHeart failureInhibitor therapyCardiac dysfunctionPrognostic importanceFiltration rateSurvival advantageMortality rateOverall populationEnd pointTherapy
2010
Effect of Right Ventricular Function and Venous Congestion on Cardiorenal Interactions During the Treatment of Decompensated Heart Failure
Testani JM, Khera AV, St. John Sutton MG, Keane MG, Wiegers SE, Shannon RP, Kirkpatrick JN. Effect of Right Ventricular Function and Venous Congestion on Cardiorenal Interactions During the Treatment of Decompensated Heart Failure. The American Journal Of Cardiology 2010, 105: 511-516. PMID: 20152246, PMCID: PMC2995805, DOI: 10.1016/j.amjcard.2009.10.020.Peer-Reviewed Original ResearchMeSH KeywordsAgedBiomarkersCardiac Output, LowCohort StudiesCreatinineDiureticsFemaleGlomerular Filtration RateHeart FailureHospitals, UniversityHumansHyperemiaIncidenceKidney DiseasesKidney Function TestsLength of StayMaleMiddle AgedNatriuretic Peptide, BrainPredictive Value of TestsRetrospective StudiesRisk AssessmentRisk FactorsSeverity of Illness IndexUltrasonographyVentricular Dysfunction, RightConceptsSignificant RV dysfunctionDecompensated heart failureRV dysfunctionRenal functionGlomerular filtration rateVenous congestionCardiac outputHeart failureFiltration rateAcute decompensated heart failureMultiple echocardiographic methodsRight ventricular dysfunctionWorsening Renal FunctionRight ventricular functionCardiorenal interactionsRenal outcomesVentricular dysfunctionRV dilationRV functionVentricular functionDischarge diagnosisConsecutive admissionsEchocardiographic methodsLower incidenceHigh incidence