1995
Lymphocyte adhesion-dependent calcium signaling in human endothelial cells.
Pfau S, Leitenberg D, Rinder H, Smith BR, Pardi R, Bender JR. Lymphocyte adhesion-dependent calcium signaling in human endothelial cells. Journal Of Cell Biology 1995, 128: 969-978. PMID: 7533170, PMCID: PMC2120392, DOI: 10.1083/jcb.128.5.969.Peer-Reviewed Original ResearchConceptsEC Ca2Endothelial cellsEC alterationsLymphocyte-endothelial interactionsNatural killer cellsImmune effector cellsTumor necrosis factorHuman umbilical vein endothelial cellsCytosolic free calcium changesUmbilical vein endothelial cellsVascular endothelial cellsHuman umbilical vein ECsAllogeneic CD3Lymphocyte subsetsVein endothelial cellsHuman endothelial cellsNK cellsEffector cellsKiller cellsVascular toneInflammatory responseNecrosis factorSecond messenger pathwaysExtracellular influxCytokine activation
1992
Early recognition of a discordant xenogeneic organ by human circulating lymphocytes.
Inverardi L, Samaja M, Motterlini R, Mangili F, Bender J, Pardi R. Early recognition of a discordant xenogeneic organ by human circulating lymphocytes. The Journal Of Immunology 1992, 149: 1416-23. PMID: 1386865, DOI: 10.4049/jimmunol.149.4.1416.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntigens, DifferentiationAntigens, Differentiation, T-LymphocyteCD3 ComplexCell AdhesionCytotoxicity, ImmunologicEndothelium, VascularHeart TransplantationHumansImmunity, CellularKiller Cells, NaturalLymphocyte Function-Associated Antigen-1Lymphocyte SubsetsMyocardiumRatsReceptors, Antigen, T-CellReceptors, FcReceptors, IgGTransplantation, HeterologousConceptsNK cellsXenogeneic organsCell-mediated immune mechanismsHuman lymphocytesAntibody-independent pathwayLymphocyte phenotypic analysisCell-mediated mechanismsHuman NK cellsNK cell adhesionPretreatment of lymphocytesAnti-CD18 antibodiesDiscordant xenograft rejectionHuman circulating lymphocytesEx vivo modelRat endothelial cellsCD3-CD16Vascular resistanceLymphocyte subsetsXenograft rejectionCirculating lymphocytesCoronary systemEarly recognitionImmune mechanismsT lymphocytesCell sequestration