2024
The mortality burden of cachexia or weight loss in patients with colorectal or pancreatic cancer: A systematic literature review
Dunne R, Crawford J, Smoyer K, McRae T, Rossulek M, Revkin J, Tarasenko L, Bonomi P. The mortality burden of cachexia or weight loss in patients with colorectal or pancreatic cancer: A systematic literature review. Journal Of Cachexia Sarcopenia And Muscle 2024, 15: 1628-1640. PMID: 39095951, PMCID: PMC11446707, DOI: 10.1002/jcsm.13510.Peer-Reviewed Original ResearchWeight loss categoriesSystematic literature reviewPancreatic cancerColorectal cancerAssessment of weight changeStatistically significant poorer survivalLoss categoriesUnintentional weight lossRisk of cachexiaWeight lossPoor survivalInternational consensusAssociated with significantly poorer survivalMortality burdenLiterature reviewEligibility criteriaPRISMA guidelinesCancer-associated cachexiaColorectalProgressive functional impairmentClinical practiceFunctional impairmentWasting disordersPoor prognosisWeight changeMortality burden of pre‐treatment weight loss in patients with non‐small‐cell lung cancer: A systematic literature review and meta‐analysis
Bonomi P, Crawford J, Dunne R, Roeland E, Smoyer K, Siddiqui M, McRae T, Rossulek M, Revkin J, Tarasenko L. Mortality burden of pre‐treatment weight loss in patients with non‐small‐cell lung cancer: A systematic literature review and meta‐analysis. Journal Of Cachexia Sarcopenia And Muscle 2024, 15: 1226-1239. PMID: 38650388, PMCID: PMC11294038, DOI: 10.1002/jcsm.13477.Peer-Reviewed Original ResearchNon-small-cell lung cancerInternational consensus criteriaHazard ratioStatistical heterogeneityMeta-analysisWeight lossLung cancerSubgroup analysisPre-treatment weight lossAssociated with inferior survivalImpact of cachexiaKaplan-Meier curvesRandom-effects modelInferior survivalOverall survivalWorse survivalSurvival outcomesHigher mortality riskAdult patientsPoor prognosisClinical decision-makingClinical trialsMultivariate analysisCachexiaIndependent reviewers screened titles
2023
The mortality burden of cachexia in patients with colorectal or pancreatic cancer: A systematic literature review.
Dunne R, Bonomi P, Crawford J, Smoyer K, McRae T, Rossulek M, Revkin J, Tarasenko L. The mortality burden of cachexia in patients with colorectal or pancreatic cancer: A systematic literature review. Journal Of Clinical Oncology 2023, 41: 87-87. DOI: 10.1200/jco.2023.41.4_suppl.87.Peer-Reviewed Original ResearchPancreatic cancerPoor survivalInternational Consensus Diagnostic CriteriaRisk of cachexiaUnintentional weight lossCancer-associated cachexiaSystematic literature reviewConsensus diagnostic criteriaProgressive functional impairmentPoor prognosisColorectal cancerUnivariate analysisMortality burdenFunctional impairmentCachexiaPRISMA guidelinesDiagnostic criteriaEligibility criteriaPatientsClinical practiceRoutine assessmentMultivariate analysisSignificant associationWasting disorderCancer