2006
Long-term assessment of cardiac function after dose-dense and -intense sequential doxorubicin (A), paclitaxel (T), and cyclophosphamide (C) as adjuvant therapy for high risk breast cancer
Abu-Khalaf MM, Juneja V, Chung GG, DiGiovanna MP, Sipples R, McGurk M, Zelterman D, Haffty B, Reiss M, Wackers FJ, Lee FA, Burtness BA. Long-term assessment of cardiac function after dose-dense and -intense sequential doxorubicin (A), paclitaxel (T), and cyclophosphamide (C) as adjuvant therapy for high risk breast cancer. Breast Cancer Research And Treatment 2006, 104: 341-349. PMID: 17051423, DOI: 10.1007/s10549-006-9413-7.Peer-Reviewed Original ResearchConceptsLeft ventricular ejection fractionEnd of chemotherapyEquilibrium radionuclide angiographyBreast cancerAdjuvant therapySequential doxorubicinCardiac functionIpsilateral axillary lymph nodesHigh-risk breast cancerRisk breast cancerClinical heart failureInitiation of chemotherapyAxillary lymph nodesVentricular ejection fractionEnd of therapyLong-term cardiotoxicityMedian absolute changeEligible patientsFilgrastim supportLate cardiotoxicityAxillary nodesAsymptomatic declineEjection fractionHeart failureLymph nodes
1988
Oral Terbutaline Augments Cardiac Performance in Chronic Obstructive Pulmonary Disease
Chan C, Loke J, Snyder P, Wackers F, Mattera J, Matthay R. Oral Terbutaline Augments Cardiac Performance in Chronic Obstructive Pulmonary Disease. The American Journal Of The Medical Sciences 1988, 296: 33-38. PMID: 3044105, DOI: 10.1097/00000441-198807000-00007.Peer-Reviewed Original ResearchConceptsChronic obstructive pulmonary diseaseObstructive pulmonary diseaseVentricular ejection fractionSubmaximal steady-state exerciseOral terbutalineSteady-state exerciseEjection fractionPulmonary diseaseSevere chronic obstructive pulmonary diseaseLeft ventricular ejection fractionFirst-pass radionuclide angiographySystolic pump performancePlacebo-controlled trialState exerciseExpiratory volumeBlood pressureCardiopulmonary effectsPlacebo dayHemodynamic measurementsVital capacityRadionuclide angiographyCardiac functionSubmaximal exerciseCardiac performanceHeart rate
1985
195mGold for Assessment of Cardiac Function
Wackers F, Berger H, Hoffer P, Lange R, Zaret B. 195mGold for Assessment of Cardiac Function. Developments In Nuclear Medicine 1985, 197-221. DOI: 10.1007/978-94-009-5022-1_8.Peer-Reviewed Original ResearchCardiac functionFirst-pass studiesGated cardiac blood pool imagingCardiac blood pool imagingInitial clinical experienceReticulo-endothelial systemEquilibrium radionuclide angiocardiographyBlood pool imagingSerial assessmentRadionuclide angiocardiographyClinical experienceClinical useRadionuclide of choiceInteresting clinical applicationsRed cellsTc99Clinical applicationRadiotracerTotal numberHoursAngiocardiographyKidneyDoseMinimal time interval