Featured Publications
Assessment of Prognostic Value of Left Ventricular Global Longitudinal Strain for Early Prediction of Chemotherapy-Induced Cardiotoxicity
Oikonomou EK, Kokkinidis DG, Kampaktsis PN, Amir EA, Marwick TH, Gupta D, Thavendiranathan P. Assessment of Prognostic Value of Left Ventricular Global Longitudinal Strain for Early Prediction of Chemotherapy-Induced Cardiotoxicity. JAMA Cardiology 2019, 4: 1007-1018. PMID: 31433450, PMCID: PMC6705141, DOI: 10.1001/jamacardio.2019.2952.Peer-Reviewed Original ResearchMeSH KeywordsAntineoplastic AgentsCardiotoxicityEarly DiagnosisEchocardiographyHeart VentriclesHumansNeoplasmsStroke VolumeVentricular Dysfunction, LeftVentricular Function, LeftConceptsCancer therapy-related cardiac dysfunctionGlobal longitudinal strainLeft ventricular global longitudinal strainVentricular global longitudinal strainPrognostic valueCutoff valuePublication biasMeasurement of GLSNew-onset heart failure symptomsAbsolute global longitudinal strainWorse global longitudinal strainLarge prospective multicenter studyLeft ventricular ejection fractionDiscriminatory performanceLongitudinal strainChemotherapy-Induced CardiotoxicityGLS cutoff valueSubclinical ventricular dysfunctionHeart failure symptomsProspective multicenter studyVentricular ejection fractionCochrane Library databasesRisk of biasOptimal cutoff valueBetter prognostic performance
2019
The Prognostic Role of Late Gadolinium Enhancement in Aortic Stenosis A Systematic Review and Meta-Analysis
Papanastasiou CA, Kokkinidis DG, Kampaktsis PN, Bikakis I, Cunha DK, Oikonomou EK, Greenwood JP, Garcia MJ, Karamitsos TD. The Prognostic Role of Late Gadolinium Enhancement in Aortic Stenosis A Systematic Review and Meta-Analysis. JACC Cardiovascular Imaging 2019, 13: 385-392. PMID: 31326491, DOI: 10.1016/j.jcmg.2019.03.029.Peer-Reviewed Original ResearchConceptsLate gadolinium enhancementAortic stenosisCardiac magnetic resonanceCause mortalityGadolinium enhancementLGE-CMRSystematic reviewA Systematic ReviewStrongest univariate predictorsRandom-effects modelBaseline characteristicsHazard ratioPrognostic roleRisk stratificationAdverse outcomesPrognostic valueUnivariate predictorsPooled analysisMyocardial fibrosisInclusion criteriaCardiac diseaseRegional fibrosisPatientsElectronic databasesMeta-Analysis