2018
Variation in the Use of Warfarin and Direct Oral Anticoagulants in Atrial Fibrillation and Associated Cost Implications
Rodwin BA, Salami JA, Spatz ES, Valero-Elizondo J, Virani SS, Blankstein R, Blaha MJ, Nasir K, Desai NR. Variation in the Use of Warfarin and Direct Oral Anticoagulants in Atrial Fibrillation and Associated Cost Implications. The American Journal Of Medicine 2018, 132: 61-70.e1. PMID: 30290193, DOI: 10.1016/j.amjmed.2018.09.026.Peer-Reviewed Original ResearchConceptsDirect oral anticoagulantsUse of DOACsAtrial fibrillationOral anticoagulantsDiseases Ninth Edition (ICD-9) codesPocket costsProportion of patientsUse of warfarinNinth Edition codesMedical Expenditure Panel SurveyPrescription drug useTotal drug expendituresPrescription drug spendingWarfarin useAnticoagulant useNationwide cohortClinical factorsMedication useEdition codesStudy populationInternational ClassificationDrug useFibrillationClinical groupsAnticoagulantsQuality Improvement Initiatives to Reduce Mortality: An Opportunity to Engage Palliative Care and Improve Advance Care Planning
Flieger SP, Spatz E, Cherlin EJ, Curry LA. Quality Improvement Initiatives to Reduce Mortality: An Opportunity to Engage Palliative Care and Improve Advance Care Planning. American Journal Of Hospice And Palliative Medicine® 2018, 36: 97-104. PMID: 30122054, DOI: 10.1177/1049909118794149.Peer-Reviewed Original ResearchConceptsAdvance care planningPalliative careCare planningQuality improvement initiativesAcute myocardial infarction mortalityPalliative care trainingImprovement initiativesMayo Clinic Care NetworkMyocardial infarction mortalityQuality improvement staffEnd of lifeAcute eventPatient goalsAMI mortalityCare trainingSecondary analysisMortalityFamily preferencesCare networkCarePatientsCliniciansQuality outcomesFamily goalsHospital executivesAssociation of the US Department of Justice Investigation of Implantable Cardioverter-Defibrillators and Devices Not Meeting the Medicare National Coverage Determination, 2007-2015
Desai NR, Bourdillon PM, Parzynski CS, Brindis RG, Spatz ES, Masters C, Minges KE, Peterson P, Masoudi FA, Oetgen WJ, Buxton A, Zipes DP, Curtis JP. Association of the US Department of Justice Investigation of Implantable Cardioverter-Defibrillators and Devices Not Meeting the Medicare National Coverage Determination, 2007-2015. JAMA 2018, 320: 63-71. PMID: 29971398, PMCID: PMC6583049, DOI: 10.1001/jama.2018.8151.Peer-Reviewed Original ResearchConceptsPrimary prevention ICDsNon-Medicare beneficiariesAbsolute decreaseNational Cardiovascular Data Registry ICD RegistrySerial cross-sectional analysisStudy periodImplantable cardioverter defibrillatorRelative decreaseCross-sectional analysisProportion of devicesInitial ICDICD RegistryPrimary preventionCardioverter defibrillatorMAIN OUTCOMEMedicare beneficiariesUS hospitalsHospital groupHospitalICDMore rapid decreasesModest decreaseDepartmentMedicareUS DepartmentComparison of Prevalence, Awareness, Treatment, and Control of Cardiovascular Risk Factors in China and the United States
Lu Y, Wang P, Zhou T, Lu J, Spatz ES, Nasir K, Jiang L, Krumholz HM. Comparison of Prevalence, Awareness, Treatment, and Control of Cardiovascular Risk Factors in China and the United States. Journal Of The American Heart Association 2018, 7: e007462. PMID: 29374046, PMCID: PMC5850247, DOI: 10.1161/jaha.117.007462.Peer-Reviewed Original ResearchMeSH KeywordsAgedAntihypertensive AgentsAttitude of Health PersonnelBlood GlucoseBlood PressureBody Mass IndexCardiovascular DiseasesChinaDiabetes MellitusDyslipidemiasFemaleHealth Knowledge, Attitudes, PracticeHealth Status DisparitiesHumansHypertensionHypolipidemic AgentsLipidsLongitudinal StudiesMaleMiddle AgedNutrition SurveysObesityPractice Patterns, Physicians'PrevalencePrognosisRisk AssessmentRisk FactorsTime FactorsUnited StatesWaist CircumferenceConceptsHigher stroke prevalenceCardiovascular risk factorsHigh-sensitivity C-reactive proteinBody mass indexC-reactive proteinRisk factorsBlood pressureWaist circumferenceMass indexStroke prevalenceCardiovascular risk factor profileHigher mean blood pressureControl of hypertensionMean blood pressureBlood pressure levelsRisk factor profileComparison of prevalenceRepresentative population sampleLower ratesDyslipidemia awarenessSevere hypertensionHemoglobin A1cHypertension treatmentControl ratePlasma glucoseNational Trends in Nonstatin Use and Expenditures Among the US Adult Population From 2002 to 2013: Insights From Medical Expenditure Panel Survey
Salami JA, Warraich HJ, Valero‐Elizondo J, Spatz ES, Desai NR, Rana JS, Virani SS, Blankstein R, Khera A, Blaha MJ, Blumenthal RS, Katzen BT, Lloyd‐Jones D, Krumholz HM, Nasir K. National Trends in Nonstatin Use and Expenditures Among the US Adult Population From 2002 to 2013: Insights From Medical Expenditure Panel Survey. Journal Of The American Heart Association 2018, 7: e007132. PMID: 29358195, PMCID: PMC5850149, DOI: 10.1161/jaha.117.007132.Peer-Reviewed Original ResearchAdultAgedAtherosclerosisDatabases, FactualDrug CostsDrug PrescriptionsDyslipidemiasFemaleHealth Care SurveysHealth ExpendituresHealthcare DisparitiesHumansHydroxymethylglutaryl-CoA Reductase InhibitorsHypolipidemic AgentsLongitudinal StudiesMaleMedically UninsuredMiddle AgedPractice Patterns, Physicians'Racial GroupsRetrospective StudiesRisk FactorsSex FactorsSocioeconomic FactorsTime FactorsTreatment OutcomeUnited States
2017
National Trends in Statin Use and Expenditures in the US Adult Population From 2002 to 2013: Insights From the Medical Expenditure Panel Survey
Salami JA, Warraich H, Valero-Elizondo J, Spatz ES, Desai NR, Rana JS, Virani SS, Blankstein R, Khera A, Blaha MJ, Blumenthal RS, Lloyd-Jones D, Nasir K. National Trends in Statin Use and Expenditures in the US Adult Population From 2002 to 2013: Insights From the Medical Expenditure Panel Survey. JAMA Cardiology 2017, 2: 56-65. PMID: 27842171, DOI: 10.1001/jamacardio.2016.4700.Peer-Reviewed Original ResearchConceptsAtherosclerotic cardiovascular diseaseStatin useAdults 40 yearsUS adult populationAdult populationMedical Expenditure Panel Survey databaseRepresentative US adult populationUS adults 40 yearsRetrospective longitudinal cohort studyHigh-intensity doseHigh-risk groupLongitudinal cohort studyMedical Expenditure Panel SurveyGeneral adult populationBrand-name statinsCohort studyStatin usersCardiovascular diseaseMedical conditionsMAIN OUTCOMEUS adultsGeneral populationStatinsOOP costsGeneric statins
2014
Sexual Activity and Counseling in the First Month After Acute Myocardial Infarction Among Younger Adults in the United States and Spain
Lindau ST, Abramsohn EM, Bueno H, D'Onofrio G, Lichtman JH, Lorenze NP, Mehta Sanghani R, Spatz ES, Spertus JA, Strait K, Wroblewski K, Zhou S, Krumholz HM. Sexual Activity and Counseling in the First Month After Acute Myocardial Infarction Among Younger Adults in the United States and Spain. Circulation 2014, 130: 2302-2309. PMID: 25512442, PMCID: PMC4322946, DOI: 10.1161/circulationaha.114.012709.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsCounselingFemaleHumansLongitudinal StudiesMaleMiddle AgedMyocardial InfarctionPhysician-Patient RelationsProspective StudiesRisk AssessmentSex FactorsSexual BehaviorSexual Dysfunction, PhysiologicalSexual Dysfunctions, PsychologicalSpainUnited StatesYoung AdultConceptsAcute myocardial infarctionSexual activityMyocardial infarctionPatient experienceYoung AMI Patients (VIRGO) studyBaseline sexual activityPhysicians counsel patientsRisk-adjusted analysisMen ages 18Sample of womenPhysician counselingCounsel patientsMedian ageSociety guidelinesFemale genderHeart rateSexual inactivityU.S. womenAge 18First monthPatientsYoung adultsPatient studiesCounselingWomen