2016
Association Between a Prolonged PR Interval and Outcomes of Cardiac Resynchronization Therapy
Friedman DJ, Bao H, Spatz ES, Curtis JP, Daubert JP, Al-Khatib SM. Association Between a Prolonged PR Interval and Outcomes of Cardiac Resynchronization Therapy. Circulation 2016, 134: 1617-1628. PMID: 27760795, PMCID: PMC5418126, DOI: 10.1161/circulationaha.116.022913.Peer-Reviewed Original ResearchConceptsHeart failure hospitalizationFailure hospitalizationPR intervalImplantable cardioverter defibrillatorNational Cardiovascular Data Registry ICD RegistryCardiac resynchronization therapy candidatesIncident heart failure hospitalizationReal-world comparative effectivenessCRT-eligible patientsReceipt of CRTChronic kidney diseaseCardiac resynchronization therapyCRT-D patientsCoronary artery diseaseProlonged PR intervalComparative effectiveness analysisMore comorbiditiesArtery diseaseDiabetes mellitusICD recipientsICD RegistryResynchronization therapyAtrial arrhythmiasKidney diseaseCardioverter defibrillator
2014
Sex-Specific Mortality Risk by QRS Morphology and Duration in Patients Receiving CRT Results From the NCDR
Zusterzeel R, Curtis JP, Caños DA, Sanders WE, Selzman KA, Piña IL, Spatz ES, Bao H, Ponirakis A, Varosy PD, Masoudi FA, Strauss DG. Sex-Specific Mortality Risk by QRS Morphology and Duration in Patients Receiving CRT Results From the NCDR. Journal Of The American College Of Cardiology 2014, 64: 887-894. PMID: 25169173, DOI: 10.1016/j.jacc.2014.06.1162.Peer-Reviewed Original ResearchConceptsLeft bundle branch blockNational Cardiovascular Data RegistryLonger QRS durationQRS durationQRS morphologyHazard ratioMortality riskBetter survivalCardiac resynchronization therapy defibrillator implantationImplantable Cardioverter-Defibrillator RegistrySex-specific mortality risksCRT-D implantationCRT-D patientsBundle branch blockLower mortality riskSex differencesComparator groupBranch blockData registryBetter outcomesPatientsLower mortalitySurvival curvesMortalityWomen