2022
Association Between Depressive Symptoms and Cardiac Structure and Function in a Peruvian Population
Santiago C, Peña M, Brown T, Shakil S, Januzzi J, Velazquez E, Miranda J, Rivera D, Checkley W. Association Between Depressive Symptoms and Cardiac Structure and Function in a Peruvian Population. Global Heart 2022, 17: 78. PMID: 36382157, PMCID: PMC9615600, DOI: 10.5334/gh.981.Peer-Reviewed Original ResearchConceptsSignificant depressive symptomsDepressive symptomsHeart failureCardiac structureTransthoracic echocardiographyEpidemiological Studies Depression ScaleCRONICAS Cohort StudyDiastolic relaxation velocityCause of disabilityMultivariable linear regressionNon-depressed subjectsCohort studyEchocardiographic measuresMiddle-income countriesWorse outcomesDepressive disorderDepression ScaleCardiac diseaseRelaxation velocityDepression symptomsNon-depressed participantsSymptomsPeruvian populationRelevant covariatesAdult participants
2017
Approaches to Sustainable Capacity Building for Cardiovascular Disease Care in Kenya
Barasa FA, Vedanthan R, Pastakia SD, Crowe SJ, Aruasa W, Sugut WK, White R, Ogola ES, Bloomfield GS, Velazquez EJ. Approaches to Sustainable Capacity Building for Cardiovascular Disease Care in Kenya. Cardiology Clinics 2017, 35: 145-152. PMID: 27886785, DOI: 10.1016/j.ccl.2016.08.014.Peer-Reviewed Original ResearchConceptsCardiovascular disease careHealth care infrastructureDiseases of povertyMiddle-income countriesDisease careCardiovascular diseaseNoncommunicable diseasesTherapeutic strategiesDiagnostic capacityHigh-quality medicationsCare infrastructureEpidemic levelsHealth careDiseasePhysical injuryCareTraffic accidents
2016
Tackling NCD in LMIC Achievements and Lessons Learned From the NHLBI–UnitedHealth Global Health Centers of Excellence Program
Engelgau M, Sampson U, Rabadan-Diehl C, Smith R, Miranda J, Bloomfield G, Belis D, Narayan K, National Health L, Rubinstein A, He J, Alam D, Peters D, Wu Y, Yan L, Merson M, Ramirez M, Caballero B, Xavier D, Yusuf S, Prabhakaran D, Narayan K, Kimaiyo S, Velazquez E, Denman C, Cornejo E, de Zapien J, Rosales C, Miranda J, Gilman R, Levitt N, Gaziano T, Ghannem H, Laatikainen T, Rabadan-Diehl C, Engelgau M, Belis D, Sampson U, Smith R, Dianis N, Wolbach T, Matta G, Gutierrez L, Elorriaga N, Poggio R, Irazola V, Bazzano L, Bhuiya A, Wazed A, Khan A, Siddiquee A, Islam A, Khan J, Uddin J, Hasan K, Khanam M, Yunus M, Chowdhury M, Monalisa N, Alam N, Streatfield P, Ahmed S, Parvin S, Ali T, Niessen L, Hossain M, Koehlmoos T, Standing H, Lucas H, Bleich S, Anderson G, Trujillo A, Mirelman A, Hao J, Zhang J, Tian M, Huang P, Luo R, Fang W, Li X, Feng X, Li Z, Deal K, Peterson E, DeLong E, Zhou B, Shi J, Neal B, Jan S, Li N, McMahon S, Zhang J, Sun J, Elliot P, Zhao Y, Zhang Y, Yao C, Sun N, Han Q, Shen R, Niu W, Wang Y, Ke Y, Huang Y, Leeder S, Lopez A, Zhang R, Yu Y, Roman A, Mendoza C, Roche D, Mejicano G, Cordova M, Kroker M, Fort M, Letona P, Kanter R, Garcia R, Murillo S, Chacon V, Montero R, Lopez E, Peña L, Castro M, Dengo A, Ulate E, Alvarado N, Sibrian J, Alegria A, Gutierrez A, Fontes F, Sigamani A, Kamath D, Xavier F, Deepthi K, Anupama M, Mathu N, George N, Rahul P, Pais P, Girish P, Thomas S, Usha T, Thomas T, Joshi R, Chidambaram N, Gupta R, Chow C, Pogue J, O'Donnell M, Devereaux P, Misquith D, Agrawal T, Fathima F, Reddy K, Shivashankar R, Ajay V, Khan H, Kadir M, Masood M, Fatmi Z, Krishnan A, Singh K, Tandon N, Khadgawat R, Menon V, Sethi B, Unnikrishnan A, Hutcheson M, Ali M, Cunningham S, Patel S, Gujral U, Desai A, Mohan D, Pradeepa R, Mohan V, Viswanathan V, Sahay R, Shah S, Bantwal G, Varthakavi P, Nair M, Akwanalo C, Lagat D, Barasa F, Koech M, Sugut W, Korir B, Mosol P, Ali S, Sherman C, Carter J, Bloomfield G, Binanay C, Vedanthan R, Bernabé-Ortiz A, León-Velarde F, Smith G, Málaga G, García H, Casas J, Sacksteder K, Smeeth L, Huicho L, Rivera M, Gamboa R, Ebrahim S, Montori V, Wise R, Checkley W, Diette G, Nojilana B, Majikela-Dlangamandla B, Sylvester C, Malan J, Murphy K, Steyn K, van Niekerk L, Mash R, Puoane T, Kim G, Pandya A, Abrahams-Gessel S, Rhode H, Pather M, Andrade A, Garcia B, Velasco C, Medina D, Bravo D, Munguia D, Bateman E, Castro F, Schneider H, Ibarra I, Zulu J, Felix J, Tribe K, Bobrow K, Fairall L, Folb N, Murillo N, Pacheco N, Rodriguez P, Navarro P, Flores R, Van Zyl Smit R, Meddoza R, Surka S, Van Haght S, Hernandez Y, Tsolekile L, Jeridi G, Harrabi I, Maatoug J, Boughammoura L, Chaieb L, Mrizek N, Gaha R, Limam K, Amimi S, Gaha K, Gamra H, Al'Absi M, Vartiainen E, Moore C, Spillan D, Cooper K, Mitchell M, Kirby R, Gao Y, Aluko E. Tackling NCD in LMIC Achievements and Lessons Learned From the NHLBI–UnitedHealth Global Health Centers of Excellence Program. Global Heart 2016, 11: 5-15. PMID: 27102018, PMCID: PMC4843818, DOI: 10.1016/j.gheart.2015.12.016.Peer-Reviewed Original ResearchConceptsHealth centersUnitedHealth GroupNoncommunicable disease burdenPriority health issuesBiomedical Research CentreMiddle-income countriesBlood InstituteLung diseaseNational HeartDisease burdenHealth issuesSpecific country settingsCountry settingsProgram’s overall goalSettingFuture investigatorsResearch CenterLungCenterDiseaseNCD
2015
Building Sustainable Capacity for Cardiovascular Care at a Public Hospital in Western Kenya
Binanay CA, Akwanalo CO, Aruasa W, Barasa FA, Corey GR, Crowe S, Esamai F, Einterz R, Foster MC, Gardner A, Kibosia J, Kimaiyo S, Koech M, Korir B, Lawrence JE, Lukas S, Manji I, Maritim P, Ogaro F, Park P, Pastakia SD, Sugut W, Vedanthan R, Yanoh R, Velazquez EJ, Bloomfield GS. Building Sustainable Capacity for Cardiovascular Care at a Public Hospital in Western Kenya. Journal Of The American College Of Cardiology 2015, 66: 2550-2560. PMID: 26653630, PMCID: PMC4680855, DOI: 10.1016/j.jacc.2015.09.086.Peer-Reviewed Original ResearchConceptsMiddle-income countriesPublic referral hospitalCardiovascular disease deathsWorld Health Organization frameworkResource-limited settingsHealth care systemReferral hospitalSubspecialty careDisease deathsCardiovascular healthChronic diseasesCardiovascular diseaseCardiovascular careMedical CenterCardiovascular servicesInfectious diseasesHealth systemCare systemDiseaseHealth partnershipsHospitalStepwise approachCareWestern KenyaAcademic partnershipsHuman Immunodeficiency Virus and Heart Failure in Low- and Middle-Income Countries
Bloomfield GS, Alenezi F, Barasa FA, Lumsden R, Mayosi BM, Velazquez EJ. Human Immunodeficiency Virus and Heart Failure in Low- and Middle-Income Countries. JACC Heart Failure 2015, 3: 579-590. PMID: 26251085, PMCID: PMC4530470, DOI: 10.1016/j.jchf.2015.05.003.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusHeart failureMiddle-income countriesImmunodeficiency virusChronic diseasesBurden of HIVTraditional cardiovascular risk factorsCommon cardiac diagnosesCardiovascular risk factorsLarge observational studiesLife expectancySuccessful combination therapyCare of peopleAntiretroviral therapyClinical characteristicsTreatment patternsSociety guidelinesCombination therapyRisk factorsClinical studiesObservational studyDiagnostic criteriaCardiac diagnosisHigh mortalityCardiac glycosides
2014
HIV and Noncommunicable Cardiovascular and Pulmonary Diseases in Low- and Middle-Income Countries in the ART Era
Bloomfield GS, Khazanie P, Morris A, Rabadán-Diehl C, Benjamin LA, Murdoch D, Radcliff VS, Velazquez EJ, Hicks C. HIV and Noncommunicable Cardiovascular and Pulmonary Diseases in Low- and Middle-Income Countries in the ART Era. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2014, 67: s40-s53. PMID: 25117960, PMCID: PMC4133739, DOI: 10.1097/qai.0000000000000257.Peer-Reviewed Original ResearchConceptsHIV-positive patientsAntiretroviral therapyHIV infectionMiddle-income countriesPulmonary diseaseCoronary artery disease/myocardial infarctionLong-term HIV infectionEffective antiretroviral therapyHIV-seropositive patientsLong-term morbidityPulmonary arterial hypertensionObstructive lung diseaseHIV-positive personsLong-term outcomesChronic noncommunicable diseasesEffective prevention strategiesPotential adverse effectsPulmonary complicationsArterial hypertensionHeart failureLung diseasePulmonary conditionsMyocardial infarctionEarly recognitionART eraOptimizing linkage and retention to hypertension care in rural Kenya (LARK hypertension study): study protocol for a randomized controlled trial
Vedanthan R, Kamano JH, Naanyu V, Delong AK, Were MC, Finkelstein EA, Menya D, Akwanalo CO, Bloomfield GS, Binanay CA, Velazquez EJ, Hogan JW, Horowitz CR, Inui TS, Kimaiyo S, Fuster V. Optimizing linkage and retention to hypertension care in rural Kenya (LARK hypertension study): study protocol for a randomized controlled trial. Trials 2014, 15: 143. PMID: 24767476, PMCID: PMC4113229, DOI: 10.1186/1745-6215-15-143.Peer-Reviewed Original ResearchMeSH KeywordsBlack PeopleBlood PressureCell PhoneClinical ProtocolsCommunicationCommunity Health ServicesCommunity Health WorkersCost-Benefit AnalysisHealth BehaviorHealth Care CostsHealth Knowledge, Attitudes, PracticeHumansHypertensionKenyaMotivational InterviewingPatient CompliancePatientsProfessional-Patient RelationsResearch DesignRural Health ServicesTime FactorsTreatment OutcomeConceptsCommunity health workersHypertension careBlood pressureHealth workersHypertensive individualsMethods/designThis studyCo-primary outcome measuresNon-communicable disease managementHypertension care programDisability-adjusted life yearsSystolic blood pressureOne-year changeHealth Belief ModelCost-effectiveness analysisUsual careMiddle-income countriesHypertension managementHypertension treatmentControl rateRisk factorsOutcome measuresDesignThis studyBehavioral communication strategyCare programLife yearsNurse Management of Hypertension in Rural Western Kenya: Implementation Research to Optimize Delivery
Vedanthan R, Kamano JH, Horowitz CR, Ascheim D, Velazquez EJ, Kimaiyo S, Fuster V. Nurse Management of Hypertension in Rural Western Kenya: Implementation Research to Optimize Delivery. Annals Of Global Health 2014, 80: 5-12. PMID: 24751560, PMCID: PMC4036099, DOI: 10.1016/j.aogh.2013.12.002.Peer-Reviewed Original ResearchConceptsRural western KenyaNurse managementBlood pressureNoncommunicable disease managementSystolic blood pressurePrimary outcome measureLong-term treatmentWestern KenyaHypertensive patientsHypertensive individualsMiddle-income countriesHypertension managementHypertension treatmentControl rateRisk factorsHypertensionOutcome measuresOptimize deliveryFull-time equivalentsEffectiveness of strategiesImplementation researchNursesDisease managementFeasibility testingRecord-keeping tool
2012
Conditions That Predispose to Pulmonary Hypertension and Right Heart Failure in Persons Exposed to Household Air Pollution in LMIC
Bloomfield GS, Lagat DK, Akwanalo OC, Carter EJ, Lugogo N, Vedanthan R, Velazquez EJ, Kimaiyo S, Sherman CB. Conditions That Predispose to Pulmonary Hypertension and Right Heart Failure in Persons Exposed to Household Air Pollution in LMIC. Global Heart 2012, 7: 249-259. PMID: 23687634, PMCID: PMC3653331, DOI: 10.1016/j.gheart.2012.06.015.Peer-Reviewed Original ResearchRight heart failurePulmonary hypertensionHousehold air pollutionHeart failureMiddle-income countriesAdverse cardiovascular health effectsRight heart functionHealth effectsHuman immunodeficiency virusCardiovascular health effectsPre-existing conditionsCommon comorbiditiesTuberculosis infectionImmunodeficiency virusCommon causeHypertensionCommon conditionRespiratory conditionsHeart functionCommon exposureMultifactorial natureLarge burdenAir pollutionSignificant exposureExposure