2022
Clinical, functional and prognostic implications of severe atrial dilation in secondary mitral regurgitation
Layoun H, Mentias A, Akintoye E, Matta M, Kanaan C, Daou R, Ramchand J, Burns D, Gillinov A, Bhattacharya S, Puri R, Collier P, Griffin B, Kapadia S, Harb S. Clinical, functional and prognostic implications of severe atrial dilation in secondary mitral regurgitation. Open Heart 2022, 9: e001996. PMID: 35383126, PMCID: PMC8984044, DOI: 10.1136/openhrt-2022-001996.Peer-Reviewed Original ResearchMeSH KeywordsAdultDilatationEchocardiographyFemaleHumansMaleMitral ValveMitral Valve InsufficiencyPrognosisConceptsSecondary mitral regurgitationAtrial dilationMitral regurgitationPrognostic implicationsSevere left atrial dilationSevere secondary mitral regurgitationLA reservoir strainLeft atrial dilationLeft ventricle dysfunctionPoor prognostic indicatorMV interventionVentricle dysfunctionMore diabetesAdult patientsTransthoracic echocardiographyEjection fractionIndependent predictorsAtrial fibrillationReservoir strainWorse prognosisPrognostic indicatorMR severityBetter outcomesFunctional alterationsPatients
2018
In‐hospital outcomes of transcatheter mitral valve repair with Mitraclip in patients with pulmonary hypertension: Insights from the National Inpatient Sample
Ahmed A, Akintoye E, Adegbala O, Yassin A, Subahi A, Bangura L, Abubakar H, Elder M, Shokr M, Afonso L. In‐hospital outcomes of transcatheter mitral valve repair with Mitraclip in patients with pulmonary hypertension: Insights from the National Inpatient Sample. Catheterization And Cardiovascular Interventions 2018, 94: e30-e36. PMID: 30506974, DOI: 10.1002/ccd.27997.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overCardiac CatheterizationClinical Decision-MakingDatabases, FactualFemaleHeart Valve ProsthesisHeart Valve Prosthesis ImplantationHospital MortalityHumansHypertension, PulmonaryMaleMiddle AgedMitral ValveMitral Valve InsufficiencyPatient SelectionPostoperative ComplicationsPrevalenceProsthesis DesignRecovery of FunctionRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeUnited StatesConceptsTranscatheter mitral valve repairNational Inpatient SamplePulmonary hypertensionMitral valve repairHospital outcomesValve repairInpatient SamplePre-existing pulmonary hypertensionPrevalence of PHPostoperative deep vein thrombosisAcute respiratory failureCohort of patientsDeep vein thrombosisMedian hospital costsHemorrhage requiring transfusionLength of stayPH groupCardiogenic shockPostoperative sepsisRespiratory failureHome dischargeInpatient mortalityPeriprocedural outcomesProhibitive riskPulmonary embolism
2017
Usefulness of the Mitral Regurgitation Severity Index to Assess the Severity of Chronic Mitral Regurgitation
Afonso L, Shokr M, Akintoye E, Briasoulis A, Alesh I, Alani A, Mahajan N, Veeranna V, Mostafa A, Zmily H, Telila T, Zalawadiya S. Usefulness of the Mitral Regurgitation Severity Index to Assess the Severity of Chronic Mitral Regurgitation. The American Journal Of Cardiology 2017, 120: 304-308. PMID: 28550931, DOI: 10.1016/j.amjcard.2017.04.027.Peer-Reviewed Original ResearchMeSH KeywordsBlood Flow VelocityChronic DiseaseEchocardiography, Doppler, ColorEchocardiography, TransesophagealFemaleFollow-Up StudiesHumansMaleMiddle AgedMitral ValveMitral Valve InsufficiencyPredictive Value of TestsReproducibility of ResultsRetrospective StudiesROC CurveSeverity of Illness IndexConceptsSevere mitral regurgitationMitral regurgitationTime-velocity integralVelocity integralNonsevere mitral regurgitationChronic mitral regurgitationInter-rater reproducibilityOptimal diagnostic accuracyDerivation cohortMitral inflowValidation cohortGood inter-rater reproducibilityHigh interobserver variabilityMR severityInter-rater agreementLevel IIMean differenceDiagnostic accuracyInterobserver variabilitySeverity IndexCut pointsRegurgitationPatientsCohortSeverity