2020
Aortic Valve Replacement for Severe Aortic Stenosis Before and During the Era of Transcatheter Aortic Valve Implantation
Akintoye E, Ando T, Sandio A, Adegbala O, Salih M, Zubairu J, Oseni A, Sistla P, Alqasrawi M, Egbe A, Mentias A, Afonso L, Briasoulis A, Panaich S, Desai M. Aortic Valve Replacement for Severe Aortic Stenosis Before and During the Era of Transcatheter Aortic Valve Implantation. The American Journal Of Cardiology 2020, 126: 73-81. PMID: 32336533, DOI: 10.1016/j.amjcard.2020.03.038.Peer-Reviewed Original ResearchConceptsSevere aortic stenosisAortic valve replacementNational Inpatient SampleTAVI eraAortic stenosisMean annual changeValve replacementFavorable short-term outcomesTranscatheter aortic valve replacementTranscatheter aortic valve implantationRate of AVRAcute kidney injuryRate of strokeAortic valve implantationShort-term outcomesRisk-adjusted ratesHospital mortalityPre-TAVIHospital outcomesKidney injuryHome dischargeHospital dischargePacemaker implantationValve implantationMedian length
2019
The impact of safety‐net burden on in‐hospital outcomes after surgical aortic valve replacement
Ando T, Adegbala O, Akintoye E, Briasoulis A, Takagi H. The impact of safety‐net burden on in‐hospital outcomes after surgical aortic valve replacement. Journal Of Cardiac Surgery 2019, 34: 1178-1184. PMID: 31441545, DOI: 10.1111/jocs.14187.Peer-Reviewed Original ResearchConceptsSurgical aortic valve replacementSafety-net burdenAortic valve replacementSAVR outcomesValve replacementAcute kidney injuryMajor perioperative complicationsHospital-level characteristicsNationwide Inpatient SampleLength of staySafety-net hospitalNumber of admissionsHospital mortalityNonroutine dischargeValvular surgeryHospital outcomesHospital stayKidney injuryPerioperative complicationsDisadvantaged patientsInpatient SampleHospital costsUnadjusted modelsHospitalPatients
2018
In‐hospital outcomes of transcatheter mitral valve repair with Mitraclip in patients with pulmonary hypertension: Insights from the National Inpatient Sample
Ahmed A, Akintoye E, Adegbala O, Yassin A, Subahi A, Bangura L, Abubakar H, Elder M, Shokr M, Afonso L. In‐hospital outcomes of transcatheter mitral valve repair with Mitraclip in patients with pulmonary hypertension: Insights from the National Inpatient Sample. Catheterization And Cardiovascular Interventions 2018, 94: e30-e36. PMID: 30506974, DOI: 10.1002/ccd.27997.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overCardiac CatheterizationClinical Decision-MakingDatabases, FactualFemaleHeart Valve ProsthesisHeart Valve Prosthesis ImplantationHospital MortalityHumansHypertension, PulmonaryMaleMiddle AgedMitral ValveMitral Valve InsufficiencyPatient SelectionPostoperative ComplicationsPrevalenceProsthesis DesignRecovery of FunctionRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeUnited StatesConceptsTranscatheter mitral valve repairNational Inpatient SamplePulmonary hypertensionMitral valve repairHospital outcomesValve repairInpatient SamplePre-existing pulmonary hypertensionPrevalence of PHPostoperative deep vein thrombosisAcute respiratory failureCohort of patientsDeep vein thrombosisMedian hospital costsHemorrhage requiring transfusionLength of stayPH groupCardiogenic shockPostoperative sepsisRespiratory failureHome dischargeInpatient mortalityPeriprocedural outcomesProhibitive riskPulmonary embolismIs Transcatheter Aortic Valve Replacement Better Than Surgical Aortic Valve Replacement in Patients With Chronic Obstructive Pulmonary Disease? A Nationwide Inpatient Sample Analysis
Ando T, Adegbala O, Akintoye E, Ashraf S, Pahuja M, Briasoulis A, Takagi H, Grines C, Afonso L, Schreiber T. Is Transcatheter Aortic Valve Replacement Better Than Surgical Aortic Valve Replacement in Patients With Chronic Obstructive Pulmonary Disease? A Nationwide Inpatient Sample Analysis. Journal Of The American Heart Association 2018, 7: e008408. PMID: 29606641, PMCID: PMC5907603, DOI: 10.1161/jaha.117.008408.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAortic ValveAortic Valve StenosisCost SavingsCost-Benefit AnalysisDatabases, FactualFemaleHealth StatusHeart Valve Prosthesis ImplantationHospital CostsHospital MortalityHumansInpatientsLength of StayMaleMiddle AgedPostoperative ComplicationsPulmonary Disease, Chronic ObstructiveRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTranscatheter Aortic Valve ReplacementTreatment OutcomeUnited StatesConceptsTranscatheter aortic valve replacementAortic valve replacementValve replacementCOPD patientsChronic obstructive pulmonary disease patientsAortic valve replacement resultsNationwide Inpatient Sample AnalysisSurgical aortic valve replacementObstructive pulmonary disease patientsChronic obstructive pulmonary diseaseNationwide Inpatient Sample databaseRespiratory-related complicationsAcute kidney injuryAcute respiratory failurePropensity-matched cohortPulmonary disease patientsNoninvasive mechanical ventilationObstructive pulmonary diseaseAcute myocardial infarctionRespiratory related complicationsHospital mortalitySAVR patientsHospital stayKidney injuryRespiratory failure
2017
Early Prosthetic Valve Dysfunction Due to Bioprosthetic Valve Thrombosis The Role of Echocardiography
Egbe A, Pislaru S, Ali M, Khan A, Boler A, Schaff H, Akintoye E, Connolly H, Nkomo V, Pellikka P. Early Prosthetic Valve Dysfunction Due to Bioprosthetic Valve Thrombosis The Role of Echocardiography. JACC Cardiovascular Imaging 2017, 11: 951-958. PMID: 29055629, DOI: 10.1016/j.jcmg.2017.06.022.Peer-Reviewed Original ResearchConceptsProsthetic valve dysfunctionBioprosthetic valve thrombosisTransthoracic echocardiographyPVD diagnosisValve thrombosisValve implantationRetrospective case-control studyAcute disease processPatients ages 61Role of echocardiographyRoutine transthoracic echocardiographyCase-control studyMen 61Symptomatic deteriorationMost patientsValve dysfunctionAppropriate therapyInitial diagnosisSF patientsBioprosthetic valvesTimely diagnosisPatient's conditionBaseline gradientAge 61Disease processHospital outcomes of transcatheter versus surgical aortic valve replacement in female in the United States
Ando T, Akintoye E, Telila T, Briasoulis A, Takagi H, Schreiber T, Afonso L, Grines C. Hospital outcomes of transcatheter versus surgical aortic valve replacement in female in the United States. Catheterization And Cardiovascular Interventions 2017, 91: 813-819. PMID: 28990736, DOI: 10.1002/ccd.27362.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAortic ValveAortic Valve StenosisComorbidityCost SavingsCost-Benefit AnalysisDatabases, FactualExtracorporeal Membrane OxygenationFemaleHeart Valve Prosthesis ImplantationHospital CostsHospital MortalityHumansMiddle AgedPostoperative ComplicationsRisk AssessmentRisk FactorsSex FactorsTime FactorsTranscatheter Aortic Valve ReplacementTreatment OutcomeUnited StatesConceptsSurgical aortic valve replacementTranscatheter aortic valve replacementAortic valve replacementExtracorporeal membrane oxygenationTAVR patientsValve replacementPrimary endpointCardiac surgeryMembrane oxygenationFemale patientsMyocardial infarctionOdds ratioNationwide Inpatient Sample databaseRisk of needAcute kidney injuryNew pacemaker implantationNonfatal myocardial infarctionConcomitant cardiac surgeryPerioperative cardiac arrestMedian hospital costsAcute myocardial infarctionLength of stayPropensity score analysisHospital mortalityNonroutine dischargeFactors associated with postoperative atrial fibrillation and other adverse events after cardiac surgery
Akintoye E, Sellke F, Marchioli R, Tavazzi L, Mozaffarian D. Factors associated with postoperative atrial fibrillation and other adverse events after cardiac surgery. Journal Of Thoracic And Cardiovascular Surgery 2017, 155: 242-251.e10. PMID: 28890081, DOI: 10.1016/j.jtcvs.2017.07.063.Peer-Reviewed Original ResearchConceptsPostoperative atrial fibrillationMajor adverse cardiovascular eventsCoronary artery bypassAdverse cardiovascular eventsArtery bypassAtrial fibrillationCardiovascular eventsCardiac surgeryHigh riskConcomitant valvularValvular surgeryCardiopulmonary bypassAdverse outcomesVentricular pacingBypass useCoronary artery bypass graft surgeryConcomitant coronary artery bypassArtery bypass graft surgeryBypass graft surgeryMultivariable-adjusted modelsCardiopulmonary bypass useType of surgeryData of patientsSpecific adverse outcomesSurgery characteristicsComparison of Hospital Outcome of Transcatheter Versus Surgical Aortic Valve Replacement in Patients With Diabetes Mellitus (from the Nationwide Inpatient Sample)
Ando T, Akintoye E, Telila T, Briasoulis A, Takagi H, Slovut D, Schreiber T, Grines C, Afonso L. Comparison of Hospital Outcome of Transcatheter Versus Surgical Aortic Valve Replacement in Patients With Diabetes Mellitus (from the Nationwide Inpatient Sample). The American Journal Of Cardiology 2017, 119: 1250-1254. PMID: 28219665, DOI: 10.1016/j.amjcard.2016.12.026.Peer-Reviewed Original ResearchMeSH KeywordsAcute Kidney InjuryAgedAged, 80 and overBlood TransfusionDatabases, FactualDiabetes MellitusExtracorporeal Membrane OxygenationFemaleHeart Valve Prosthesis ImplantationHospital CostsHospital MortalityHumansLength of StayMaleMyocardial InfarctionPacemaker, ArtificialPostoperative ComplicationsSepsisTranscatheter Aortic Valve ReplacementUnited StatesConceptsSurgical aortic valve replacementTranscatheter aortic valve replacementAortic valve replacementTAVR patientsValve replacementDM patientsHospital outcomesOdds ratioOutcomes of TAVRTranscatheter Versus Surgical Aortic Valve ReplacementNationwide Inpatient Sample databasePrimary end pointNew pacemaker implantationDiabetes mellitus patientsMean hospitalization costAcute myocardial infarctionLength of staySAVR patientsSAVR proceduresCardiac complicationsCause mortalityPerioperative complicationsPostoperative sepsisRespiratory complicationsVascular complications