2018
Incidence, Trends, and Predictors of Palliative Care Consultation After Aortic Valve Replacement in the United States
Ando T, Adegbala O, Uemura T, Akintoye E, Ashraf S, Briasoulis A, Takagi H, Afonso L. Incidence, Trends, and Predictors of Palliative Care Consultation After Aortic Valve Replacement in the United States. Journal Of Palliative Care 2018, 34: 111-117. PMID: 30587081, DOI: 10.1177/0825859718819433.Peer-Reviewed Original ResearchConceptsSurgical aortic valve replacementTranscatheter aortic valve replacementAortic valve replacementPC referral rateAdjusted odds ratioPC consultPC referralValve replacementIndex hospitalizationPC consultationReferral ratesTransapical transcatheter aortic valve replacementAortic valve replacement patientsNationwide Inpatient Sample databaseValve replacement patientsPalliative care consultPalliative care consultationMultivariable regression analysisCare consultTAVR cohortAcceptable morbidityInpatient mortalityReplacement patientsElectrolyte derangementsNIS databaseVenous congestion and pulmonary vascular function in Fontan circulation: Implications for prognosis and treatment
Egbe A, Reddy Y, Khan A, Al-Otaibi M, Akintoye E, Obokata M, Borlaug B. Venous congestion and pulmonary vascular function in Fontan circulation: Implications for prognosis and treatment. International Journal Of Cardiology 2018, 271: 312-316. PMID: 30223363, PMCID: PMC6146405, DOI: 10.1016/j.ijcard.2018.05.039.Peer-Reviewed Original ResearchConceptsPulmonary vascular resistance indexCentral venous pressureSystemic venous congestionPulmonary vascular functionFontan patientsVenous congestionFontan circulationVascular functionElevated pulmonary vascular resistance indexAdult Fontan patientsVascular resistance indexPulmonary blood flowSub-pulmonary ventricleCongenital heart diseaseLow-level elevationsPulmonary vascular structureFontan groupFontan populationAntiplatelet therapyCause mortalityCardiac catheterizationComposite endpointVenous pressureMulticenter studyAdverse outcomes
2017
Mechanism for temporal changes in exercise capacity after Fontan palliation: Role of Doppler echocardiography
Egbe A, Khan A, Miranda W, Ammash N, Warnes C, Said S, Taggart N, Akintoye E, Veldtman G, Connolly H. Mechanism for temporal changes in exercise capacity after Fontan palliation: Role of Doppler echocardiography. American Heart Journal 2017, 196: 144-152. PMID: 29421006, DOI: 10.1016/j.ahj.2017.10.010.Peer-Reviewed Original ResearchMeSH KeywordsAcademic Medical CentersAdultAge FactorsCohort StudiesDouble Outlet Right VentricleEchocardiography, DopplerExercise TestExercise ToleranceFollow-Up StudiesFontan ProcedureHeart Defects, CongenitalHumansMaleMichiganOxygen ConsumptionPulmonary AtresiaRetrospective StudiesTime FactorsTreatment OutcomeTricuspid AtresiaYoung AdultConceptsCardiopulmonary exercise testTransthoracic echocardiogramLV function indicesFontan palliationExercise capacityChronotropic indexFunction IndexLeft ventricleAdult Fontan patientsFontan conversion operationSystemic left ventriclePeak oxygen consumptionSerial transthoracic echocardiogramsFontan patientsFontan conversionDoppler echocardiographyRetrospective reviewDoppler hemodynamicsMean ageHemodynamic mechanismsExercise testMayo ClinicCPET dataPatientsTemporal improvementNationwide survival after inhospital cardiac arrest before and after 2010 cardiopulmonary resuscitation guidelines: 2007–2014
Mallikethi-Reddy S, Akintoye E, Rubenfire M, Briasoulis A, Grines C, Afonso L. Nationwide survival after inhospital cardiac arrest before and after 2010 cardiopulmonary resuscitation guidelines: 2007–2014. International Journal Of Cardiology 2017, 249: 231-233. PMID: 28987317, DOI: 10.1016/j.ijcard.2017.09.199.Peer-Reviewed Original ResearchConceptsInhospital cardiac arrestCardiopulmonary resuscitation guidelinesCPR guidelinesCardiac arrestResuscitation guidelinesSurvival trendsAmerican Heart AssociationSignificant improvementInhospital survivalStudy cohortMean ageHeart AssociationStudy populationSurvival rateStudy periodSurvivalCPRGuidelinesRole of diastolic function indices in the risk stratification of patients with mixed aortic valve disease
Egbe A, Khan A, Boler A, Said S, Geske J, Miranda W, Akintoye E, Connolly H, Warnes C, Oh J. Role of diastolic function indices in the risk stratification of patients with mixed aortic valve disease. European Heart Journal - Cardiovascular Imaging 2017, 19: 668-674. PMID: 28655164, DOI: 10.1093/ehjci/jex148.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAnalysis of VarianceAortic Valve InsufficiencyAortic Valve StenosisAsymptomatic DiseasesCohort StudiesConfidence IntervalsDiastoleEchocardiographyFemaleHumansMaleMiddle AgedMonitoring, PhysiologicPredictive Value of TestsPrognosisRetrospective StudiesRisk AssessmentSex FactorsStroke VolumeSurvival RateUnited StatesConceptsAortic valve replacementCardiovascular adverse eventsRelative wall thicknessMixed aortic valve diseaseDiastolic function indicesAortic valve diseaseCardiac deathRisk stratificationValve diseaseFunction IndexHigh-risk patient subsetsPost-operative risk stratificationSevere left ventricular dysfunctionAtrial volume indexHeart failure hospitalizationTricuspid regurgitation velocityEarly diastolic velocityLeft ventricular dysfunctionMultivariable risk factorsAsymptomatic patientsCardiovascular morbidityFailure hospitalizationPrimary endpointSecondary endpointsVentricular dysfunction