2020
Palliative Care in Ruptured Aortic Aneurysm in the United States: A Retrospective Analysis of Nationwide Inpatient Sample Database
Ando T, Adegbala O, Uemura T, Ashraf S, Akintoye E, Pahuja M, Afonso L, Briasoulis A, Takagi H. Palliative Care in Ruptured Aortic Aneurysm in the United States: A Retrospective Analysis of Nationwide Inpatient Sample Database. Angiology 2020, 71: 633-640. PMID: 32249588, DOI: 10.1177/0003319720917239.Peer-Reviewed Original ResearchConceptsLength of stayHospitalization costsPalliative careAortic aneurysmRepair groupNationwide Inpatient Sample databasePalliative care referralPC referral ratePercutaneous repair groupRuptured Aortic AneurysmSurgical repair groupNationwide Inpatient SamplePC referralCare referralInpatient SampleReferral ratesRetrospective analysisAdmissionStudy periodSample databaseFurther studiesStayAneurysmsReferralCareRural–Urban Disparities in Intracerebral Hemorrhage Mortality in the USA: Preliminary Findings from the National Inpatient Sample
Otite F, Akano E, Akintoye E, Khandelwal P, Malik A, Chaturvedi S, Rosand J. Rural–Urban Disparities in Intracerebral Hemorrhage Mortality in the USA: Preliminary Findings from the National Inpatient Sample. Neurocritical Care 2020, 32: 715-724. PMID: 32232726, PMCID: PMC7223184, DOI: 10.1007/s12028-020-00950-2.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAphasiaCerebral HemorrhageComorbidityCraniotomyDeglutition DisordersFemaleHealthcare DisparitiesHospital Bed CapacityHospital MortalityHospitals, RuralHospitals, UrbanHumansHydrocephalusMaleMiddle AgedRespiration, ArtificialRisk FactorsUnited StatesYoung AdultConceptsNational Inpatient SampleSex-adjusted mortalityUrban hospitalRural hospitalsICH patientsInpatient SampleJoinpoint regressionIntracerebral hemorrhage mortalityMultivariable-adjusted modelsOdds of mortalityIntracerebral hemorrhage patientsCases of ICHHospital deathHospital mortalityMultivariable adjustmentUrban patientsRural patientsStroke careHemorrhage patientsMedicare insuranceRural-urban disparitiesPatientsResultsFrom 2004HospitalMortality gap
2019
Clinical and economic burden of heparin-induced thrombocytopenia in hospitalized patients undergoing percutaneous peripheral arterial interventions
Subahi A, Osman M, Adegbala O, Abubakar H, Kheiri B, Yassin A, Khalid M, Akintoye E, Eljack A, Osman K, Alkhouli M. Clinical and economic burden of heparin-induced thrombocytopenia in hospitalized patients undergoing percutaneous peripheral arterial interventions. Vascular 2019, 28: 81-86. PMID: 31382836, DOI: 10.1177/1708538119868615.Peer-Reviewed Original ResearchConceptsVenous thrombosis/pulmonary embolismAcute kidney injuryKidney injuryIschemic strokePulmonary embolismHigh riskDeep venous thrombosis/pulmonary embolismPercutaneous peripheral arterial interventionsICD-9-CM codesHospital mortality differenceProlonged hospital stayHospital-level characteristicsPeripheral arterial interventionsNational Inpatient SampleHospital outcomesHospital stayIntervention patientsAbsence of heparinBaseline characteristicsHome dischargeLonger hospitalizationArterial interventionsHospitalized patientsInpatient SampleThrombocytopeniaClinical Impact of Atrial Fibrillation on Short-Term Outcomes and In-Hospital Mortality in Patients with Takotsubo Syndrome: A Propensity-Matched National Study
Yassin A, Subahi A, Adegbala O, Abubakar H, Dawdy J, Mishra T, Akintoye E, Shereef H, Ghandour M, Alhusain R, Shokr M, Oviedo C, Afonso L. Clinical Impact of Atrial Fibrillation on Short-Term Outcomes and In-Hospital Mortality in Patients with Takotsubo Syndrome: A Propensity-Matched National Study. Cardiovascular Revascularization Medicine 2019, 21: 522-526. PMID: 31439442, DOI: 10.1016/j.carrev.2019.07.022.Peer-Reviewed Original ResearchConceptsCost of hospitalizationAtrial fibrillationHospital mortalityHospital complicationsVentricular arrhythmiasNational Inpatient Sample databasePropensity score-matched analysisMajor cardiac complicationsTakotsubo syndrome patientsIn-Hospital MortalityNon-routine dischargeAtrial fibrillation groupAtrial fibrillation patientsShort-term outcomesNational Inpatient SampleLength of stayPotential confounding factorsCardiac complicationsHospital stayFibrillation groupFibrillation patientsSecondary outcomesTakotsubo syndromePrimary outcomeCardiac arrestTrends and Outcomes of Infective Endocarditis in Adults With Tetralogy of Fallot: A Review of the National Inpatient Sample Database
Egbe A, Vallabhajosyula S, Akintoye E, Connolly H. Trends and Outcomes of Infective Endocarditis in Adults With Tetralogy of Fallot: A Review of the National Inpatient Sample Database. Canadian Journal Of Cardiology 2019, 35: 721-726. PMID: 31151707, DOI: 10.1016/j.cjca.2019.02.006.Peer-Reviewed Original ResearchConceptsHealth care resource utilizationTetralogy of FallotProsthetic valve implantationNational Inpatient SampleCongenital heart diseaseHospital mortalityValve implantationInfective endocarditisHeart diseaseRisk factorsTOF patientsInflation-adjusted hospitalization costsNational Inpatient Sample databaseCyanotic congenital heart diseaseIncidence of endocarditisLength of stayPacemaker/defibrillatorLow socioeconomic classPopulation-based riskHospital dischargeSecondary outcomesPrimary outcomeHospitalization costsBlack raceInpatient SamplePredictors of Hospital Cost After Transcatheter Aortic Valve Implantation in the United States: From the Nationwide Inpatient Sample Database
Ando T, Adegbala O, Villablanca P, Akintoye E, Ashraf S, Briasoulis A, Telila T, Takagi H, Grines C, Schreiber T, Bhatt D, Afonso L. Predictors of Hospital Cost After Transcatheter Aortic Valve Implantation in the United States: From the Nationwide Inpatient Sample Database. The American Journal Of Cardiology 2019, 123: 1142-1148. PMID: 30658917, DOI: 10.1016/j.amjcard.2018.12.044.Peer-Reviewed Original ResearchMeSH KeywordsAged, 80 and overAortic Valve StenosisDatabases, FactualFemaleHospital CostsHospital MortalityHospitalizationHumansIncidenceInpatientsMalePatient Acceptance of Health CarePostoperative ComplicationsPropensity ScoreRisk FactorsTime FactorsTranscatheter Aortic Valve ReplacementUnited StatesConceptsTranscatheter aortic valve implantationNationwide Inpatient Sample databaseHigh-cost groupHigher hospitalization costsAortic valve implantationHospitalization costsValve implantationHospital costsSample databaseSurgical aortic valve replacementCost groupsHigher co-morbidity burdenAcute kidney injuryAcute respiratory failureAortic valve replacementPeripheral vascular diseaseCo-morbidity burdenCost of hospitalizationLength of stayMultivariable regression analysisLow-cost groupHigh incremental costPost-TAVITAVI hospitalizationsCardiogenic shock
2018
Incidence, Trends, and Predictors of Palliative Care Consultation After Aortic Valve Replacement in the United States
Ando T, Adegbala O, Uemura T, Akintoye E, Ashraf S, Briasoulis A, Takagi H, Afonso L. Incidence, Trends, and Predictors of Palliative Care Consultation After Aortic Valve Replacement in the United States. Journal Of Palliative Care 2018, 34: 111-117. PMID: 30587081, DOI: 10.1177/0825859718819433.Peer-Reviewed Original ResearchConceptsSurgical aortic valve replacementTranscatheter aortic valve replacementAortic valve replacementPC referral rateAdjusted odds ratioPC consultPC referralValve replacementIndex hospitalizationPC consultationReferral ratesTransapical transcatheter aortic valve replacementAortic valve replacement patientsNationwide Inpatient Sample databaseValve replacement patientsPalliative care consultPalliative care consultationMultivariable regression analysisCare consultTAVR cohortAcceptable morbidityInpatient mortalityReplacement patientsElectrolyte derangementsNIS databaseClinical Impact of Diabetes Mellitus on Short-Term Outcomes andIn-Hospital Mortality of Cardiac Mechanical Support with Left Ventricular Assist Device (LVAD): A Retrospective Study from a National Database
Yassin A, Subahi A, Adegbala O, Abubakar H, Akintoye E, Ahmed A, Ismail A, Elhag A, Kambal A, Alade A, Shokr M, Weinberger J, Levine D, Afonso L. Clinical Impact of Diabetes Mellitus on Short-Term Outcomes andIn-Hospital Mortality of Cardiac Mechanical Support with Left Ventricular Assist Device (LVAD): A Retrospective Study from a National Database. Cardiovascular Revascularization Medicine 2018, 20: 883-886. PMID: 30578171, DOI: 10.1016/j.carrev.2018.12.011.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedDatabases, FactualDiabetes MellitusFemaleHeart FailureHeart-Assist DevicesHospital MortalityHumansMaleMiddle AgedProsthesis DesignProsthesis ImplantationRecovery of FunctionRegistriesRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeUnited StatesVentricular Dysfunction, LeftVentricular Function, LeftConceptsLeft ventricular assist deviceCardiac mechanical supportDiabetes mellitusCost of hospitalizationCardiac supportVentricular assist deviceHospital mortalityDiabetic patientsHeart failureClinical impactMultivariable logistic regression model analysisAssist deviceStage D heart failureAdvanced congestive heart failureNational Inpatient Sample databasePost-LVAD complicationsShort-term complicationsCongestive heart failureLogistic regression model analysisHospital-level characteristicsImpact of diabetesRegression model analysisInpatient mortalityLVAD implantationSecondary outcomesIn‐hospital outcomes of transcatheter mitral valve repair with Mitraclip in patients with pulmonary hypertension: Insights from the National Inpatient Sample
Ahmed A, Akintoye E, Adegbala O, Yassin A, Subahi A, Bangura L, Abubakar H, Elder M, Shokr M, Afonso L. In‐hospital outcomes of transcatheter mitral valve repair with Mitraclip in patients with pulmonary hypertension: Insights from the National Inpatient Sample. Catheterization And Cardiovascular Interventions 2018, 94: e30-e36. PMID: 30506974, DOI: 10.1002/ccd.27997.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overCardiac CatheterizationClinical Decision-MakingDatabases, FactualFemaleHeart Valve ProsthesisHeart Valve Prosthesis ImplantationHospital MortalityHumansHypertension, PulmonaryMaleMiddle AgedMitral ValveMitral Valve InsufficiencyPatient SelectionPostoperative ComplicationsPrevalenceProsthesis DesignRecovery of FunctionRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeUnited StatesConceptsTranscatheter mitral valve repairNational Inpatient SamplePulmonary hypertensionMitral valve repairHospital outcomesValve repairInpatient SamplePre-existing pulmonary hypertensionPrevalence of PHPostoperative deep vein thrombosisAcute respiratory failureCohort of patientsDeep vein thrombosisMedian hospital costsHemorrhage requiring transfusionLength of stayPH groupCardiogenic shockPostoperative sepsisRespiratory failureHome dischargeInpatient mortalityPeriprocedural outcomesProhibitive riskPulmonary embolismFailure to Rescue, Hospital Volume, and In-Hospital Mortality After Transcatheter Aortic Valve Implantation
Ando T, Adegbala O, Villablanca P, Shokr M, Akintoye E, Briasoulis A, Takagi H, Schreiber T, Grines C, Afonso L. Failure to Rescue, Hospital Volume, and In-Hospital Mortality After Transcatheter Aortic Valve Implantation. The American Journal Of Cardiology 2018, 122: 828-832. PMID: 30064862, DOI: 10.1016/j.amjcard.2018.05.020.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve implantationMajor perioperative complicationsAortic valve implantationVolume hospitalsHospital volumePatient mortalityPerioperative complicationsValve implantationTransarterial transcatheter aortic valve implantationNationwide Inpatient Sample databaseCo-morbidity indexGreater hospital volumeIn-Hospital MortalityPatient mortality ratesPercentage of womenHospital mortalityMajor complicationsTAVI procedureHighest quintileMean ageLowest quintileAdjusted ratesMortality rateFourth quintileDifferent hospitalsOutcomes and Effects of Hepatic Cirrhosis in Patients Who Underwent Transcatheter Aortic Valve Implantation
Yassin A, Subahi A, Abubakar H, Akintoye E, Alhusain R, Adegbala O, Ahmed A, Elmoughrabi A, Subahi E, Pahuja M, Sahlieh A, Elder M, Kaki A, Schreiber T, Mohamad T. Outcomes and Effects of Hepatic Cirrhosis in Patients Who Underwent Transcatheter Aortic Valve Implantation. The American Journal Of Cardiology 2018, 122: 455-460. PMID: 30041889, DOI: 10.1016/j.amjcard.2018.04.013.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve implantationAortic valve implantationLiver cirrhosisCirrhotic patientsValve implantationUnderwent Transcatheter Aortic Valve ImplantationNational Inpatient Sample databasePropensity score-matched analysisNonroutine hospital dischargeSevere aortic stenosisAortic valve replacementReasonable therapeutic optionCost of hospitalizationHospital mortalityHospital stayVascular complicationsHospital dischargeInpatient mortalitySecondary outcomesValve replacementAortic stenosisPacemaker implantationPrimary outcomeProcedural complicationsClinical outcomesClinical End Points of Transcatheter Aortic Valve Implantation Compared With Surgical Aortic Valve Replacement in Patients <65 Years of Age (From the National Inpatient Sample Database)
Ando T, Akintoye E, Holmes A, Briasoulis A, Pahuja M, Takagi H, Schreiber T, Grines C, Afonso L. Clinical End Points of Transcatheter Aortic Valve Implantation Compared With Surgical Aortic Valve Replacement in Patients <65 Years of Age (From the National Inpatient Sample Database). The American Journal Of Cardiology 2018, 122: 279-283. PMID: 29880287, DOI: 10.1016/j.amjcard.2018.03.356.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAortic ValveAortic Valve StenosisCause of DeathFemaleFollow-Up StudiesHospital MortalityHumansIncidenceInpatientsLength of StayMaleMiddle AgedPostoperative ComplicationsPropensity ScoreRegistriesRetrospective StudiesRisk AssessmentRisk FactorsSurvival RateTime FactorsTranscatheter Aortic Valve ReplacementUnited StatesYoung AdultConceptsSurgical aortic valve replacementTranscatheter aortic valve implantationAortic valve replacementShorter hospital stayAortic valve implantationHospital mortalityHospital stayValve replacementValve implantationNational Inpatient Sample databaseSafe alternativeAcute kidney injuryOlder patient populationClinical end pointsAcute myocardial infarctionPropensity score analysisYears of agePostprocedure strokeKidney injuryValve surgeryVascular complicationsMajor complicationsPacemaker implantationPatient populationMyocardial infarctionRacial/ethnic differences in the prognostic utility of left ventricular mass index for incident cardiovascular disease
Akintoye E, Mahmoud K, Shokr M, Sandio A, Mallikethi‐Reddy S, Sheikh M, Adegbala O, Egbe A, Briasoulis A, Afonso L. Racial/ethnic differences in the prognostic utility of left ventricular mass index for incident cardiovascular disease. Clinical Cardiology 2018, 41: 502-509. PMID: 29663526, PMCID: PMC6490106, DOI: 10.1002/clc.22914.Peer-Reviewed Original ResearchMeSH KeywordsAgedAsianBlack or African AmericanCardiovascular DiseasesComorbidityDatabases, FactualDisease ProgressionFemaleHispanic or LatinoHumansHypertrophy, Left VentricularIncidenceMagnetic Resonance Imaging, CineMaleMiddle AgedPredictive Value of TestsPrognosisProportional Hazards ModelsRacial GroupsRisk FactorsTime FactorsUnited StatesVentricular Function, LeftVentricular RemodelingWhite PeopleConceptsLeft ventricular mass indexLeft ventricular hypertrophyNon-Hispanic whitesVentricular mass indexCVD eventsIncident CVDMass indexPrognostic utilityEthnic differencesFuture cardiovascular disease eventsOptimal cutpointCardiovascular disease eventsFuture CVD eventsIncident cardiovascular diseaseRisk stratification strategiesIncident cardiovascular outcomesMulti-Ethnic StudyRace/ethnicityCardiovascular outcomesLVMI valuesVentricular hypertrophyCardiovascular diseaseDisease eventsCox modelStratification strategiesIs Transcatheter Aortic Valve Replacement Better Than Surgical Aortic Valve Replacement in Patients With Chronic Obstructive Pulmonary Disease? A Nationwide Inpatient Sample Analysis
Ando T, Adegbala O, Akintoye E, Ashraf S, Pahuja M, Briasoulis A, Takagi H, Grines C, Afonso L, Schreiber T. Is Transcatheter Aortic Valve Replacement Better Than Surgical Aortic Valve Replacement in Patients With Chronic Obstructive Pulmonary Disease? A Nationwide Inpatient Sample Analysis. Journal Of The American Heart Association 2018, 7: e008408. PMID: 29606641, PMCID: PMC5907603, DOI: 10.1161/jaha.117.008408.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAortic ValveAortic Valve StenosisCost SavingsCost-Benefit AnalysisDatabases, FactualFemaleHealth StatusHeart Valve Prosthesis ImplantationHospital CostsHospital MortalityHumansInpatientsLength of StayMaleMiddle AgedPostoperative ComplicationsPulmonary Disease, Chronic ObstructiveRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTranscatheter Aortic Valve ReplacementTreatment OutcomeUnited StatesConceptsTranscatheter aortic valve replacementAortic valve replacementValve replacementCOPD patientsChronic obstructive pulmonary disease patientsAortic valve replacement resultsNationwide Inpatient Sample AnalysisSurgical aortic valve replacementObstructive pulmonary disease patientsChronic obstructive pulmonary diseaseNationwide Inpatient Sample databaseRespiratory-related complicationsAcute kidney injuryAcute respiratory failurePropensity-matched cohortPulmonary disease patientsNoninvasive mechanical ventilationObstructive pulmonary diseaseAcute myocardial infarctionRespiratory related complicationsHospital mortalitySAVR patientsHospital stayKidney injuryRespiratory failureRelation of Cannabis Use and Atrial Fibrillation Among Patients Hospitalized for Heart Failure
Adegbala O, Adejumo A, Olakanmi O, Akinjero A, Akintoye E, Alliu S, Edo-Osagie E, Chatterjee A. Relation of Cannabis Use and Atrial Fibrillation Among Patients Hospitalized for Heart Failure. The American Journal Of Cardiology 2018, 122: 129-134. PMID: 29685570, DOI: 10.1016/j.amjcard.2018.03.015.Peer-Reviewed Original ResearchConceptsDiagnosis of HFAtrial fibrillationHeart failureNervous systemCannabis usersOccurrence of AFUtilization Project National Inpatient SampleDiagnosis of AFCannabis useLeft ventricular dysfunctionCo-morbid conditionsSympathetic nervous systemCannabis user groupAutonomic nervous systemInotropic supportVentricular dysfunctionCardiovascular effectsSympathetic effectsSympathetic activityAutonomic effectsInpatient SampleAF diagnosisInsurance typeMain exposureLower odds
2017
Hospital outcomes of transcatheter versus surgical aortic valve replacement in female in the United States
Ando T, Akintoye E, Telila T, Briasoulis A, Takagi H, Schreiber T, Afonso L, Grines C. Hospital outcomes of transcatheter versus surgical aortic valve replacement in female in the United States. Catheterization And Cardiovascular Interventions 2017, 91: 813-819. PMID: 28990736, DOI: 10.1002/ccd.27362.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAortic ValveAortic Valve StenosisComorbidityCost SavingsCost-Benefit AnalysisDatabases, FactualExtracorporeal Membrane OxygenationFemaleHeart Valve Prosthesis ImplantationHospital CostsHospital MortalityHumansMiddle AgedPostoperative ComplicationsRisk AssessmentRisk FactorsSex FactorsTime FactorsTranscatheter Aortic Valve ReplacementTreatment OutcomeUnited StatesConceptsSurgical aortic valve replacementTranscatheter aortic valve replacementAortic valve replacementExtracorporeal membrane oxygenationTAVR patientsValve replacementPrimary endpointCardiac surgeryMembrane oxygenationFemale patientsMyocardial infarctionOdds ratioNationwide Inpatient Sample databaseRisk of needAcute kidney injuryNew pacemaker implantationNonfatal myocardial infarctionConcomitant cardiac surgeryPerioperative cardiac arrestMedian hospital costsAcute myocardial infarctionLength of stayPropensity score analysisHospital mortalityNonroutine dischargeSeasonal variation in hospitalization outcomes in patients admitted for heart failure in the United States
Akintoye E, Briasoulis A, Egbe A, Adegbala O, Alliu S, Sheikh M, Singh M, Ahmed A, Mallikethi‐Reddy S, Levine D. Seasonal variation in hospitalization outcomes in patients admitted for heart failure in the United States. Clinical Cardiology 2017, 40: 1105-1111. PMID: 28873233, PMCID: PMC6490330, DOI: 10.1002/clc.22784.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsAgedAged, 80 and overChi-Square DistributionDatabases, FactualFemaleHeart FailureHospital CostsHospital MortalityHumansIncidenceLength of StayLogistic ModelsMaleMiddle AgedMultivariate AnalysisOdds RatioPatient AdmissionPrevalenceRisk FactorsSeasonsSex FactorsTime FactorsUnited StatesYoung AdultFactors associated with postoperative atrial fibrillation and other adverse events after cardiac surgery
Akintoye E, Sellke F, Marchioli R, Tavazzi L, Mozaffarian D. Factors associated with postoperative atrial fibrillation and other adverse events after cardiac surgery. Journal Of Thoracic And Cardiovascular Surgery 2017, 155: 242-251.e10. PMID: 28890081, DOI: 10.1016/j.jtcvs.2017.07.063.Peer-Reviewed Original ResearchConceptsPostoperative atrial fibrillationMajor adverse cardiovascular eventsCoronary artery bypassAdverse cardiovascular eventsArtery bypassAtrial fibrillationCardiovascular eventsCardiac surgeryHigh riskConcomitant valvularValvular surgeryCardiopulmonary bypassAdverse outcomesVentricular pacingBypass useCoronary artery bypass graft surgeryConcomitant coronary artery bypassArtery bypass graft surgeryBypass graft surgeryMultivariable-adjusted modelsCardiopulmonary bypass useType of surgeryData of patientsSpecific adverse outcomesSurgery characteristicsHospital teaching status and trascatheter aortic valve replacement outcomes in the United States: Analysis of the national inpatient sample
Telila T, Akintoye E, Ando T, Merid O, Palla M, Mallikethi‐Reddy S, Briasoulis A, Grines C, Afonso L. Hospital teaching status and trascatheter aortic valve replacement outcomes in the United States: Analysis of the national inpatient sample. Catheterization And Cardiovascular Interventions 2017, 90: 1200-1205. PMID: 28795480, DOI: 10.1002/ccd.27236.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overChi-Square DistributionDatabases, FactualFemaleHealthcare DisparitiesHospital CostsHospital MortalityHospitals, TeachingHumansLength of StayLinear ModelsLogistic ModelsMaleMultivariate AnalysisOdds RatioPostoperative ComplicationsProcess Assessment, Health CareRegistriesRisk FactorsTime FactorsTranscatheter Aortic Valve ReplacementTreatment OutcomeUnited StatesConceptsTranscatheter aortic valve replacementAcute kidney injuryNational Inpatient SampleHospital teaching statusHospital mortalityTeaching statusInpatient SampleMechanical circulatory support devicesAortic valve replacementProcedure-related complicationsShort-term outcomesMechanical circulatory supportLength of stayCirculatory support devicesICD-9 codingHospital stayKidney injurySecondary outcomesValve replacementPrimary outcomeTAVR proceduresClinical outcomesCirculatory supportMean agePatient outcomesBiochemical risk markers and 10-year incidence of atherosclerotic cardiovascular disease: independent predictors, improvement in pooled cohort equation, and risk reclassification
Akintoye E, Briasoulis A, Afonso L. Biochemical risk markers and 10-year incidence of atherosclerotic cardiovascular disease: independent predictors, improvement in pooled cohort equation, and risk reclassification. American Heart Journal 2017, 193: 95-103. PMID: 29129262, DOI: 10.1016/j.ahj.2017.08.002.Peer-Reviewed Original ResearchConceptsPooled Cohort EquationsNet reclassification indexBiochemical risk markersBiomarker scoreCohort EquationsC-statisticRisk markersTreatment decisionsPrimary atherosclerotic cardiovascular disease (ASCVD) preventionAtherosclerotic cardiovascular disease preventionCategorical net reclassification indexSensitivity C-reactive proteinCategory-free net reclassification indexN-terminal prohormoneBrain natriuretic peptideAtherosclerotic cardiovascular diseaseCardiovascular disease preventionC-reactive proteinMulti-Ethnic StudyRate of incidentsASCVD preventionIndependent predictorsNet reclassificationNatriuretic peptideRisk reclassification