2020
Palliative Care in Ruptured Aortic Aneurysm in the United States: A Retrospective Analysis of Nationwide Inpatient Sample Database
Ando T, Adegbala O, Uemura T, Ashraf S, Akintoye E, Pahuja M, Afonso L, Briasoulis A, Takagi H. Palliative Care in Ruptured Aortic Aneurysm in the United States: A Retrospective Analysis of Nationwide Inpatient Sample Database. Angiology 2020, 71: 633-640. PMID: 32249588, DOI: 10.1177/0003319720917239.Peer-Reviewed Original ResearchConceptsLength of stayHospitalization costsPalliative careAortic aneurysmRepair groupNationwide Inpatient Sample databasePalliative care referralPC referral ratePercutaneous repair groupRuptured Aortic AneurysmSurgical repair groupNationwide Inpatient SamplePC referralCare referralInpatient SampleReferral ratesRetrospective analysisAdmissionStudy periodSample databaseFurther studiesStayAneurysmsReferralCare
2019
P4727Comparing in-hospital outcomes of transcatheter mitral valve repair vs surgical mitral valve repair in patients with pulmonary hypertension
Ahmed A, Adegbala O, Akintoye E, Alhatemi G, Aldiwani H, Yassin A, Khalid M, Mishra T, Ajam M, Abubakar H, Shokr M, Afonso L. P4727Comparing in-hospital outcomes of transcatheter mitral valve repair vs surgical mitral valve repair in patients with pulmonary hypertension. European Heart Journal 2019, 40: ehz745.1104. DOI: 10.1093/eurheartj/ehz745.1104.Peer-Reviewed Original ResearchSurgical mitral valve repairMitral valve repairTranscatheter mitral valve repairAbsolute standardized differencesValve repairTMVR groupPercutaneous interventionHigher Elixhauser comorbidity scoreStandardized morbidity ratio weightsChronic obstructive pulmonary diseaseNationwide Inpatient Sample databasePropensity scoreLow periprocedural complicationsAcute kidney injuryChronic renal failureCoronary artery bypassElixhauser comorbidity scorePulmonary hypertension patientsCongestive heart failureObstructive pulmonary diseasePrevious myocardial infarctionMedian hospital costsHospital mortalityPH patientsTMVR patientsPredictors of Hospital Cost After Transcatheter Aortic Valve Implantation in the United States: From the Nationwide Inpatient Sample Database
Ando T, Adegbala O, Villablanca P, Akintoye E, Ashraf S, Briasoulis A, Telila T, Takagi H, Grines C, Schreiber T, Bhatt D, Afonso L. Predictors of Hospital Cost After Transcatheter Aortic Valve Implantation in the United States: From the Nationwide Inpatient Sample Database. The American Journal Of Cardiology 2019, 123: 1142-1148. PMID: 30658917, DOI: 10.1016/j.amjcard.2018.12.044.Peer-Reviewed Original ResearchMeSH KeywordsAged, 80 and overAortic Valve StenosisDatabases, FactualFemaleHospital CostsHospital MortalityHospitalizationHumansIncidenceInpatientsMalePatient Acceptance of Health CarePostoperative ComplicationsPropensity ScoreRisk FactorsTime FactorsTranscatheter Aortic Valve ReplacementUnited StatesConceptsTranscatheter aortic valve implantationNationwide Inpatient Sample databaseHigh-cost groupHigher hospitalization costsAortic valve implantationHospitalization costsValve implantationHospital costsSample databaseSurgical aortic valve replacementCost groupsHigher co-morbidity burdenAcute kidney injuryAcute respiratory failureAortic valve replacementPeripheral vascular diseaseCo-morbidity burdenCost of hospitalizationLength of stayMultivariable regression analysisLow-cost groupHigh incremental costPost-TAVITAVI hospitalizationsCardiogenic shock
2018
Incidence, Trends, and Predictors of Palliative Care Consultation After Aortic Valve Replacement in the United States
Ando T, Adegbala O, Uemura T, Akintoye E, Ashraf S, Briasoulis A, Takagi H, Afonso L. Incidence, Trends, and Predictors of Palliative Care Consultation After Aortic Valve Replacement in the United States. Journal Of Palliative Care 2018, 34: 111-117. PMID: 30587081, DOI: 10.1177/0825859718819433.Peer-Reviewed Original ResearchConceptsSurgical aortic valve replacementTranscatheter aortic valve replacementAortic valve replacementPC referral rateAdjusted odds ratioPC consultPC referralValve replacementIndex hospitalizationPC consultationReferral ratesTransapical transcatheter aortic valve replacementAortic valve replacement patientsNationwide Inpatient Sample databaseValve replacement patientsPalliative care consultPalliative care consultationMultivariable regression analysisCare consultTAVR cohortAcceptable morbidityInpatient mortalityReplacement patientsElectrolyte derangementsNIS databaseComparison of In-Hospital Outcomes of Patients With-Versus-Without Ischemic Cardiomyopathy Undergoing Left Ventricular Assist Device Placement
Abubakar H, Subahi A, Adegbala O, Yassin A, Akintoye E, Abdulrahman A, Ahmed A, Alade A, Pahuja M, Afonso L. Comparison of In-Hospital Outcomes of Patients With-Versus-Without Ischemic Cardiomyopathy Undergoing Left Ventricular Assist Device Placement. The American Journal Of Cardiology 2018, 123: 414-418. PMID: 30545482, DOI: 10.1016/j.amjcard.2018.10.039.Peer-Reviewed Original ResearchConceptsVentricular assist device placementPostoperative myocardial infarctionLength of stayHospital mortalityVascular complicationsLVAD placementMyocardial infarctionEnd pointLeft ventricular assist device placementNationwide Inpatient Sample databaseST-segment myocardial infarctionDevice placementPeriprocedural vascular complicationsHeart failure etiologyIn-Hospital OutcomesPrimary end pointSecondary end pointsClinical end pointsHospital-level characteristicsCost of hospitalizationHemorrhage requiring transfusionMixed-effects logistic modelHospital outcomesFailure etiologyIschemic cardiomyopathyIncidence, Predictors, and In-Hospital Outcomes of Transcatheter Aortic Valve Implantation After Nonelective Admission in Comparison With Elective Admission: From the Nationwide Inpatient Sample Database
Ando T, Adegbala O, Villablanca P, Akintoye E, Ashraf S, Shokr M, Briasoulis A, Takagi H, Grines C, Afonso L, Schreiber T. Incidence, Predictors, and In-Hospital Outcomes of Transcatheter Aortic Valve Implantation After Nonelective Admission in Comparison With Elective Admission: From the Nationwide Inpatient Sample Database. The American Journal Of Cardiology 2018, 123: 100-107. PMID: 30360892, DOI: 10.1016/j.amjcard.2018.09.023.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve implantationNationwide Inpatient Sample databaseNonelective admissionsPropensity-matched cohortAortic valve implantationHospital mortalityValve implantationElective admissionsOutcomes of TAVITransarterial transcatheter aortic valve implantationSample databaseHigher adverse outcomesPulmonary circulation disordersAcute kidney injuryHealth resource utilizationIn-Hospital OutcomesChronic kidney diseaseIndependent risk factorCongestive heart failureHigh-risk cohortAcute myocardial infarctionCardiogenic shockHospital lengthKidney injuryRespiratory failureFailure to Rescue, Hospital Volume, and In-Hospital Mortality After Transcatheter Aortic Valve Implantation
Ando T, Adegbala O, Villablanca P, Shokr M, Akintoye E, Briasoulis A, Takagi H, Schreiber T, Grines C, Afonso L. Failure to Rescue, Hospital Volume, and In-Hospital Mortality After Transcatheter Aortic Valve Implantation. The American Journal Of Cardiology 2018, 122: 828-832. PMID: 30064862, DOI: 10.1016/j.amjcard.2018.05.020.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve implantationMajor perioperative complicationsAortic valve implantationVolume hospitalsHospital volumePatient mortalityPerioperative complicationsValve implantationTransarterial transcatheter aortic valve implantationNationwide Inpatient Sample databaseCo-morbidity indexGreater hospital volumeIn-Hospital MortalityPatient mortality ratesPercentage of womenHospital mortalityMajor complicationsTAVI procedureHighest quintileMean ageLowest quintileAdjusted ratesMortality rateFourth quintileDifferent hospitalsIs Transcatheter Aortic Valve Replacement Better Than Surgical Aortic Valve Replacement in Patients With Chronic Obstructive Pulmonary Disease? A Nationwide Inpatient Sample Analysis
Ando T, Adegbala O, Akintoye E, Ashraf S, Pahuja M, Briasoulis A, Takagi H, Grines C, Afonso L, Schreiber T. Is Transcatheter Aortic Valve Replacement Better Than Surgical Aortic Valve Replacement in Patients With Chronic Obstructive Pulmonary Disease? A Nationwide Inpatient Sample Analysis. Journal Of The American Heart Association 2018, 7: e008408. PMID: 29606641, PMCID: PMC5907603, DOI: 10.1161/jaha.117.008408.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAortic ValveAortic Valve StenosisCost SavingsCost-Benefit AnalysisDatabases, FactualFemaleHealth StatusHeart Valve Prosthesis ImplantationHospital CostsHospital MortalityHumansInpatientsLength of StayMaleMiddle AgedPostoperative ComplicationsPulmonary Disease, Chronic ObstructiveRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTranscatheter Aortic Valve ReplacementTreatment OutcomeUnited StatesConceptsTranscatheter aortic valve replacementAortic valve replacementValve replacementCOPD patientsChronic obstructive pulmonary disease patientsAortic valve replacement resultsNationwide Inpatient Sample AnalysisSurgical aortic valve replacementObstructive pulmonary disease patientsChronic obstructive pulmonary diseaseNationwide Inpatient Sample databaseRespiratory-related complicationsAcute kidney injuryAcute respiratory failurePropensity-matched cohortPulmonary disease patientsNoninvasive mechanical ventilationObstructive pulmonary diseaseAcute myocardial infarctionRespiratory related complicationsHospital mortalitySAVR patientsHospital stayKidney injuryRespiratory failureFinancial Implications and Impact of Pre-existing Atrial Fibrillation on In-Hospital Outcomes in Patients Who Underwent Transcatheter Aortic Valve Implantation (from the National Inpatient Database)
Abubakar H, Yassin A, Akintoye E, Bakhit K, Pahuja M, Shokr M, Lieberman R, Afonso L. Financial Implications and Impact of Pre-existing Atrial Fibrillation on In-Hospital Outcomes in Patients Who Underwent Transcatheter Aortic Valve Implantation (from the National Inpatient Database). The American Journal Of Cardiology 2018, 121: 1587-1592. PMID: 29622287, DOI: 10.1016/j.amjcard.2018.02.052.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAortic Valve StenosisArrhythmias, CardiacAtrial FibrillationCardiac Pacing, ArtificialCardiac TamponadeComorbidityDatabases, FactualFemaleHeart ArrestHeart FailureHospital CostsHospital MortalityHumansLength of StayLinear ModelsLogistic ModelsMaleMyocardial InfarctionPacemaker, ArtificialPericardial EffusionPostoperative ComplicationsPostoperative HemorrhageStrokeTranscatheter Aortic Valve ReplacementUnited StatesConceptsTranscatheter aortic valve implantationPre-existing atrial fibrillationLength of stayPeriprocedural cardiac complicationsAortic valve implantationAtrial fibrillationCost of hospitalizationCardiac complicationsHospital mortalityEnd pointValve implantationLonger hospital LOSUnderwent Transcatheter Aortic Valve ImplantationPre-existing AFHospital LOSIncidence of AFLonger LOSNationwide Inpatient Sample databaseIn-Hospital OutcomesPrimary end pointSecondary end pointsClinical end pointsHospital-level characteristicsMixed-effects logistic modelTAVI patients
2017
Hospital outcomes of transcatheter versus surgical aortic valve replacement in female in the United States
Ando T, Akintoye E, Telila T, Briasoulis A, Takagi H, Schreiber T, Afonso L, Grines C. Hospital outcomes of transcatheter versus surgical aortic valve replacement in female in the United States. Catheterization And Cardiovascular Interventions 2017, 91: 813-819. PMID: 28990736, DOI: 10.1002/ccd.27362.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAortic ValveAortic Valve StenosisComorbidityCost SavingsCost-Benefit AnalysisDatabases, FactualExtracorporeal Membrane OxygenationFemaleHeart Valve Prosthesis ImplantationHospital CostsHospital MortalityHumansMiddle AgedPostoperative ComplicationsRisk AssessmentRisk FactorsSex FactorsTime FactorsTranscatheter Aortic Valve ReplacementTreatment OutcomeUnited StatesConceptsSurgical aortic valve replacementTranscatheter aortic valve replacementAortic valve replacementExtracorporeal membrane oxygenationTAVR patientsValve replacementPrimary endpointCardiac surgeryMembrane oxygenationFemale patientsMyocardial infarctionOdds ratioNationwide Inpatient Sample databaseRisk of needAcute kidney injuryNew pacemaker implantationNonfatal myocardial infarctionConcomitant cardiac surgeryPerioperative cardiac arrestMedian hospital costsAcute myocardial infarctionLength of stayPropensity score analysisHospital mortalityNonroutine dischargeComparison of In-Hospital Outcomes of Transcatheter Aortic Valve Implantation Versus Surgical Aortic Valve Replacement in Obese (Body Mass Index ≥ 30 Kg/M2) Patients
Ando T, Akintoye E, Trehan N, Telila T, Briasoulis A, Takagi H, Grines C, Afonso L. Comparison of In-Hospital Outcomes of Transcatheter Aortic Valve Implantation Versus Surgical Aortic Valve Replacement in Obese (Body Mass Index ≥ 30 Kg/M2) Patients. The American Journal Of Cardiology 2017, 120: 1858-1862. PMID: 28860018, DOI: 10.1016/j.amjcard.2017.07.098.Peer-Reviewed Original ResearchMeSH KeywordsAgedAortic ValveAortic Valve StenosisBody Mass IndexComorbidityFemaleFollow-Up StudiesHospital MortalityHumansIncidenceInpatientsMaleObesityPostoperative ComplicationsPrevalencePrognosisPropensity ScoreRisk AssessmentRisk FactorsSurvival RateTime FactorsTranscatheter Aortic Valve ReplacementUnited StatesConceptsTranscatheter aortic valve implantationSurgical aortic valve replacementAortic valve replacementTAVI patientsNonroutine dischargeObese patientsValve replacementTranscatheter Aortic Valve Implantation Versus Surgical Aortic Valve ReplacementNationwide Inpatient Sample databaseHigher co-morbidity burdenCertain perioperative complicationsAcute kidney injuryIn-Hospital OutcomesShorter hospital stayAortic valve implantationCo-morbidity burdenMedian hospital costsAcute myocardial infarctionLength of stayCharlson scoreDeyo's modificationHospital mortalityCardiac complicationsHospital stayKidney injuryIncidence and Outcomes of Heparin-Induced Thrombocytopenia in Patients Undergoing Transcatheter Aortic Valve Replacement
Telila T, Akintoye E, Ando T, Merid O, Mallikethi-Reddy S, Briasoulis A, Grines C, Afonso L. Incidence and Outcomes of Heparin-Induced Thrombocytopenia in Patients Undergoing Transcatheter Aortic Valve Replacement. The American Journal Of Cardiology 2017, 120: 300-303. PMID: 28576265, DOI: 10.1016/j.amjcard.2017.04.028.Peer-Reviewed Original ResearchMeSH KeywordsAged, 80 and overAnticoagulantsAortic Valve StenosisFemaleHeparinHospital MortalityHumansIncidenceKaplan-Meier EstimateMalePostoperative ComplicationsPrognosisRetrospective StudiesRisk FactorsSurvival RateThrombocytopeniaThromboembolismTranscatheter Aortic Valve ReplacementTreatment OutcomeUnited StatesConceptsVenous thrombosis/pulmonary embolismAcute kidney injuryHospital-level characteristicsHospital stayHospital mortalityKidney injuryPulmonary embolismHospital costsTranscatheter aortic valve replacementNationwide Inpatient Sample databaseOutcomes of HITPerioperative thromboembolic complicationsLonger hospital stayOutcomes of patientsAortic valve replacementHeparin-Induced ThrombocytopeniaMedian hospital costsImpact of HITTAVR groupCumulative incidenceInpatient mortalitySecondary outcomesThromboembolic complicationsValve replacementCardiac surgeryTranscatheter aortic valve implantation in the United States: Predictors of early hospital discharge
Mallikethi‐Reddy S, Akintoye E, Telila T, Sudhakar R, Jagadeesh K, Briasoulis A, Rubenfire M, Afonso L, Grines C. Transcatheter aortic valve implantation in the United States: Predictors of early hospital discharge. Journal Of Interventional Cardiology 2017, 30: 149-155. PMID: 28247569, DOI: 10.1111/joic.12373.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve implantationEarly hospital dischargeAortic valve implantationEarly dischargeDischarge cohortPost-TAVIAortic valvuloplastyHospital dischargeBlood transfusionValve implantationPermanent pacemakerNationwide Inpatient Sample databaseMechanical circulatory support devicesAcute kidney injuryEarly discharge cohortTransfemoral TAVI approachHigher hospitalization costsMechanical circulatory supportCost of hospitalizationOverall mean ageHealthcare Utilization ProjectCirculatory support devicesHospital outcomesKidney injuryRenal failureBurden of arrhythmias in peripartum cardiomyopathy: Analysis of 9841 hospitalizations
Mallikethi-Reddy S, Akintoye E, Trehan N, Sharma S, Briasoulis A, Jagadeesh K, Rubenfire M, Grines C, Afonso L. Burden of arrhythmias in peripartum cardiomyopathy: Analysis of 9841 hospitalizations. International Journal Of Cardiology 2017, 235: 114-117. PMID: 28268089, DOI: 10.1016/j.ijcard.2017.02.084.Peer-Reviewed Original ResearchMeSH KeywordsAdultArrhythmias, CardiacCardiomyopathiesDatabases, FactualElectric CountershockElectrophysiologic Techniques, CardiacFemaleHeart ArrestHospital CostsHospital MortalityHumansLength of StayOutcome and Process Assessment, Health CarePregnancyPregnancy Complications, CardiovascularSurvival AnalysisUnited StatesConceptsBurden of arrhythmiasPeripartum cardiomyopathyHospital mortalityHospitalization costsNationwide Inpatient Sample databaseElixhauser comorbidity scoreSwan-Ganz catheterizationFrequency of arrhythmiasLength of stayHealthcare Utilization ProjectArrhythmogenic causesCardiogenic shockComorbidity scorePPM implantationBalloon pumpCoronary angiographyElectrical cardioversionCatheter ablationSignificant morbidityInpatient stayCardiac arrestCommon arrhythmiaMean agePrimary diagnosisVentricular tachycardiaTrends in Vascular Complications in High-Risk Patients Following Transcatheter Aortic Valve Replacement in the United States
Ando T, Akintoye E, Telila T, Briasoulis A, Takagi H, Grines C, Afonso L. Trends in Vascular Complications in High-Risk Patients Following Transcatheter Aortic Valve Replacement in the United States. The American Journal Of Cardiology 2017, 119: 1433-1437. PMID: 28256249, DOI: 10.1016/j.amjcard.2017.01.028.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAged, 80 and overAortic Valve StenosisComorbidityDiabetes MellitusFemaleHospital Bed CapacityHospitalsHospitals, RuralHospitals, TeachingHospitals, UrbanHumansMalePeripheral Vascular DiseasesPostoperative ComplicationsRisk FactorsSex FactorsTranscatheter Aortic Valve ReplacementUnited StatesVascular DiseasesConceptsTranscatheter aortic valve replacementHigh-risk groupAortic valve replacementHigh-risk patientsVascular complicationsVC rateValve replacementHigh riskPeripheral vascular disease patientsOverall populationNationwide Inpatient Sample databaseHigh-risk cohortVascular disease patientsContinuous longitudinal monitoringTAVR patientsCenter experienceDiabetes mellitusDisease patientsWorse outcomesInternational ClassificationPatientsSample databaseLongitudinal monitoringSignificant decreaseStatistical significanceIncidence and Survival After In-Hospital Cardiopulmonary Resuscitation in Nonelderly Adults
Mallikethi-Reddy S, Briasoulis A, Akintoye E, Jagadeesh K, Brook R, Rubenfire M, Afonso L, Grines C. Incidence and Survival After In-Hospital Cardiopulmonary Resuscitation in Nonelderly Adults. Circulation Cardiovascular Quality And Outcomes 2017, 10: e003194. PMID: 28193738, DOI: 10.1161/circoutcomes.116.003194.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsCardiopulmonary ResuscitationChi-Square DistributionDatabases, FactualFemaleHeart ArrestHospital MortalityHumansIncidenceMaleMiddle AgedMultivariate AnalysisOdds RatioPatient DischargeRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeUnited StatesYoung AdultConceptsCardiopulmonary resuscitation guidelinesHospital cardiopulmonary resuscitationNonelderly adultsResuscitation guidelinesSurvival trendsOdds of survivalCardiac arrestBlack raceFemale sexCardiopulmonary resuscitationAmerican Heart Association cardiopulmonary resuscitation guidelinesUtilization Project Nationwide Inpatient Sample databaseNationwide Inpatient Sample databaseShockable arrest rhythmOverall survival rateWeekend admissionArrest rhythmHospital dischargeShockable rhythmSignificant changesLower oddsSurvival ratePatientsStudy periodSample databaseComparison of Hospital Outcome of Transcatheter Versus Surgical Aortic Valve Replacement in Patients With Diabetes Mellitus (from the Nationwide Inpatient Sample)
Ando T, Akintoye E, Telila T, Briasoulis A, Takagi H, Slovut D, Schreiber T, Grines C, Afonso L. Comparison of Hospital Outcome of Transcatheter Versus Surgical Aortic Valve Replacement in Patients With Diabetes Mellitus (from the Nationwide Inpatient Sample). The American Journal Of Cardiology 2017, 119: 1250-1254. PMID: 28219665, DOI: 10.1016/j.amjcard.2016.12.026.Peer-Reviewed Original ResearchMeSH KeywordsAcute Kidney InjuryAgedAged, 80 and overBlood TransfusionDatabases, FactualDiabetes MellitusExtracorporeal Membrane OxygenationFemaleHeart Valve Prosthesis ImplantationHospital CostsHospital MortalityHumansLength of StayMaleMyocardial InfarctionPacemaker, ArtificialPostoperative ComplicationsSepsisTranscatheter Aortic Valve ReplacementUnited StatesConceptsSurgical aortic valve replacementTranscatheter aortic valve replacementAortic valve replacementTAVR patientsValve replacementDM patientsHospital outcomesOdds ratioOutcomes of TAVRTranscatheter Versus Surgical Aortic Valve ReplacementNationwide Inpatient Sample databasePrimary end pointNew pacemaker implantationDiabetes mellitus patientsMean hospitalization costAcute myocardial infarctionLength of staySAVR patientsSAVR proceduresCardiac complicationsCause mortalityPerioperative complicationsPostoperative sepsisRespiratory complicationsVascular complications