2020
Incidence and clinical outcomes of bleeding complications and acute limb ischemia in STEMI and cardiogenic shock
Pahuja M, Ranka S, Chehab O, Mishra T, Akintoye E, Adegbala O, Yassin A, Ando T, Thayer K, Shah P, Kimmelstiel C, Salehi P, Kapur N. Incidence and clinical outcomes of bleeding complications and acute limb ischemia in STEMI and cardiogenic shock. Catheterization And Cardiovascular Interventions 2020, 97: 1129-1138. PMID: 32473083, PMCID: PMC8344361, DOI: 10.1002/ccd.29003.Peer-Reviewed Original ResearchConceptsST-segment elevation myocardial infarctionAcute limb ischemiaLength of stayCardiogenic shockCS-STEMIHospital mortalityVascular complicationsLimb ischemiaClinical outcomesManagement of CSPercutaneous ventricular assist deviceIntra-aortic balloon pumpPercutaneous mechanical circulatory supportRetrospective cohort studyElevation myocardial infarctionMechanical circulatory supportVentricular assist deviceU.S. national databaseTandem HeartMultiorgan failureCohort studyBalloon pumpCommon complicationMembrane oxygenationCirculatory supportTrends, Outcomes, and Readmissions Among Left Ventricular Assist Device Recipients with Acute Kidney Injury Requiring Hemodialysis.
Adegbala O, Olakanmi O, Akintoye E, Inampudi C, Pahuja M, Alvarez P, Briasoulis A. Trends, Outcomes, and Readmissions Among Left Ventricular Assist Device Recipients with Acute Kidney Injury Requiring Hemodialysis. ASAIO Journal 2020, 66: 507-512. PMID: 31192850, DOI: 10.1097/mat.0000000000001036.Peer-Reviewed Original ResearchConceptsAcute kidney injuryLength of stayHospital mortalityKidney injuryLVAD recipientsMaintenance hemodialysisLVAD implantationAcute Kidney Injury Requiring HemodialysisVentricular assist device implantationVentricular assist device recipientsNational Readmission DatabaseAssist device implantationReduced hospital costsHospital outcomesPostoperative bleedingHospital dischargeRenal functionDevice implantationDevice recipientsHemodialysis therapyHospital characteristicsHospital costsHemodialysisReadmissionPatientsPalliative Care in Ruptured Aortic Aneurysm in the United States: A Retrospective Analysis of Nationwide Inpatient Sample Database
Ando T, Adegbala O, Uemura T, Ashraf S, Akintoye E, Pahuja M, Afonso L, Briasoulis A, Takagi H. Palliative Care in Ruptured Aortic Aneurysm in the United States: A Retrospective Analysis of Nationwide Inpatient Sample Database. Angiology 2020, 71: 633-640. PMID: 32249588, DOI: 10.1177/0003319720917239.Peer-Reviewed Original ResearchConceptsLength of stayHospitalization costsPalliative careAortic aneurysmRepair groupNationwide Inpatient Sample databasePalliative care referralPC referral ratePercutaneous repair groupRuptured Aortic AneurysmSurgical repair groupNationwide Inpatient SamplePC referralCare referralInpatient SampleReferral ratesRetrospective analysisAdmissionStudy periodSample databaseFurther studiesStayAneurysmsReferralCare
2019
P3603Impact of idiopathic thrombocytopenic purpura on clinical outcomes in patients with acute myocardial infarction
Chehab O, Pahuja M, Adegbala O, Akintoye E, Ramia P, Morsi R, Alrojolah L, Mishra T, Shokr M, Kanj A, Abdallah N, Tabaja H, Afonso L, Abidov A. P3603Impact of idiopathic thrombocytopenic purpura on clinical outcomes in patients with acute myocardial infarction. European Heart Journal 2019, 40: ehz745.0462. DOI: 10.1093/eurheartj/ehz745.0462.Peer-Reviewed Original ResearchIdiopathic thrombocytopenic purpuraAcute myocardial infarctionLength of stayLonger LOSNon-ITP patientsAcute ischemic strokeClinical outcomesHospital mortalitySecondary outcomesThrombocytopenic purpuraAMI patientsMyocardial infarctionACC/AHA/ESCUS National Inpatient Sample databaseNational Inpatient Sample databaseCardiovascular risk factorsPropensity-matched cohortLow platelet countManagement of patientsShort-term mortalityLong-term outcomesCoronary revascularization proceduresHospital complicationsMore comorbiditiesAnticoagulation therapyGender Differences in Outcomes After Implantation of Left Ventricular Assist Devices
Ahmed A, Adegbala O, Akintoye E, Inampudi C, Ajam M, Yassin A, Olawusi E, Shokr M, Alvarez P, Briasoulis A. Gender Differences in Outcomes After Implantation of Left Ventricular Assist Devices. The Annals Of Thoracic Surgery 2019, 109: 780-786. PMID: 31479642, DOI: 10.1016/j.athoracsur.2019.07.032.Peer-Reviewed Original ResearchConceptsLVAD implantationContinuous-flow LVADVentricular assist device implantationLeft ventricular assist deviceAcute kidney injuryAssist device implantationMost common complicationsExtracorporeal membrane oxygenationMedian hospitalization costNational Inpatient SamplePostoperative cardiac tamponadeLength of stayYears of ageVentricular assist deviceGender-specific differencesHospital mortalityPostoperative thromboembolismCardiac tamponadeHospital outcomesKidney injuryPeriprocedural complicationsPostoperative sepsisCommon complicationInpatient mortalityLVAD placementThe impact of safety‐net burden on in‐hospital outcomes after surgical aortic valve replacement
Ando T, Adegbala O, Akintoye E, Briasoulis A, Takagi H. The impact of safety‐net burden on in‐hospital outcomes after surgical aortic valve replacement. Journal Of Cardiac Surgery 2019, 34: 1178-1184. PMID: 31441545, DOI: 10.1111/jocs.14187.Peer-Reviewed Original ResearchConceptsSurgical aortic valve replacementSafety-net burdenAortic valve replacementSAVR outcomesValve replacementAcute kidney injuryMajor perioperative complicationsHospital-level characteristicsNationwide Inpatient SampleLength of staySafety-net hospitalNumber of admissionsHospital mortalityNonroutine dischargeValvular surgeryHospital outcomesHospital stayKidney injuryPerioperative complicationsDisadvantaged patientsInpatient SampleHospital costsUnadjusted modelsHospitalPatientsClinical Impact of Atrial Fibrillation on Short-Term Outcomes and In-Hospital Mortality in Patients with Takotsubo Syndrome: A Propensity-Matched National Study
Yassin A, Subahi A, Adegbala O, Abubakar H, Dawdy J, Mishra T, Akintoye E, Shereef H, Ghandour M, Alhusain R, Shokr M, Oviedo C, Afonso L. Clinical Impact of Atrial Fibrillation on Short-Term Outcomes and In-Hospital Mortality in Patients with Takotsubo Syndrome: A Propensity-Matched National Study. Cardiovascular Revascularization Medicine 2019, 21: 522-526. PMID: 31439442, DOI: 10.1016/j.carrev.2019.07.022.Peer-Reviewed Original ResearchConceptsCost of hospitalizationAtrial fibrillationHospital mortalityHospital complicationsVentricular arrhythmiasNational Inpatient Sample databasePropensity score-matched analysisMajor cardiac complicationsTakotsubo syndrome patientsIn-Hospital MortalityNon-routine dischargeAtrial fibrillation groupAtrial fibrillation patientsShort-term outcomesNational Inpatient SampleLength of stayPotential confounding factorsCardiac complicationsHospital stayFibrillation groupFibrillation patientsSecondary outcomesTakotsubo syndromePrimary outcomeCardiac arrestIncidence and predictors of readmissions to non-index hospitals after transcatheter aortic valve replacement and the impact on in-hospital outcomes: From the nationwide readmission database
Ando T, Adegbala O, Villablanca P, Akintoye E, Ashraf S, Shokr M, Siddiqui F, Takagi H, Grines C, Afonso L, Briasoulis A. Incidence and predictors of readmissions to non-index hospitals after transcatheter aortic valve replacement and the impact on in-hospital outcomes: From the nationwide readmission database. International Journal Of Cardiology 2019, 292: 50-55. PMID: 31053244, DOI: 10.1016/j.ijcard.2019.04.056.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve replacementNon-index hospitalsNon-index hospital readmissionsNon-index readmissionsAortic valve replacementNationwide Readmissions DatabaseHospital mortalityIndex hospitalHospital outcomesValve replacementHospital readmissionEndovascular transcatheter aortic valve replacementMetropolitan non-teaching hospitalsMultivariable logistic regression analysisAcute kidney injuryPredictors of readmissionAcute myocardial infarctionLength of stayLogistic regression analysisNon-teaching hospitalsElective readmissionsTAVR recipientsKidney injuryPacemaker placementHealthcare utilizationTrends, Outcomes and Readmissions among Left Ventricular Assist Device Recipients with Acute Kidney Injury Requiring Hemodialysis: An Insight from the National Readmissions Database 2012-2014
Inampudi C, Adegbala O, Akintoye E, Alvarez P, Briasoulis A. Trends, Outcomes and Readmissions among Left Ventricular Assist Device Recipients with Acute Kidney Injury Requiring Hemodialysis: An Insight from the National Readmissions Database 2012-2014. The Journal Of Heart And Lung Transplantation 2019, 38: s348. DOI: 10.1016/j.healun.2019.01.882.Peer-Reviewed Original ResearchAcute kidney injuryLength of stayPost-operative bleedingLVAD implantationHospital mortalityMaintenance hemodialysisLVAD recipientsHospital costsAcute Kidney Injury Requiring HemodialysisVentricular assist device implantationVentricular assist device recipientsAnnual national ratesNational Readmission DatabaseAssist device implantationChronic kidney diseaseAcute kidneyIndex admissionHospital outcomesKidney injuryHospital dischargeRenal functionDevice implantationDevice recipientsKidney diseaseHemodialysis therapyCharacteristics and Outcomes of Patients with Cardiogenic Shock Complicated by Acute Kidney Injury Requiring Hemodialysis
Inampudi C, Adegbala O, Akintoye E, Alvarez P, Briasoulis A. Characteristics and Outcomes of Patients with Cardiogenic Shock Complicated by Acute Kidney Injury Requiring Hemodialysis. The Journal Of Heart And Lung Transplantation 2019, 38: s63. DOI: 10.1016/j.healun.2019.01.141.Peer-Reviewed Original ResearchLength of stayCardiogenic shockOutcomes of patientsHospital mortalityAcute Kidney Injury Requiring HemodialysisPre-existing chronic kidney diseasePropensity score-matched groupsHigher comorbidity burdenAcute kidney injuryChronic kidney diseaseRenal replacement therapyHospital-level characteristicsRenal venous pressureNational Inpatient SampleComorbidity burdenHospital morbidityHospital outcomesKidney injuryElixhauser scoreRenal functionBiventricular functionDiabetes mellitusRenal perfusionVenous pressureHospitalization costsCharacteristics and Outcomes of Patients With Cardiogenic Shock Utilizing Hemodialysis for Acute Kidney Injury
Adegbala O, Inampudi C, Adejumo A, Otuonye G, Akintoye E, Elsayed R, Williams K, Alvarez P, Afonso L, Briasoulis A. Characteristics and Outcomes of Patients With Cardiogenic Shock Utilizing Hemodialysis for Acute Kidney Injury. The American Journal Of Cardiology 2019, 123: 1816-1821. PMID: 30967283, DOI: 10.1016/j.amjcard.2019.02.038.Peer-Reviewed Original ResearchConceptsLength of stayAcute kidney injuryCardiogenic shockOutcomes of patientsHospital mortalityKidney injuryTemporary mechanical supportCause of CSPropensity score-matched groupsST-elevation myocardial infarctionMechanical circulatory support devicesHigher comorbidity burdenRenal replacement therapyElevation myocardial infarctionHospital-level characteristicsRenal venous pressureNational Inpatient SampleCirculatory support devicesComorbidity burdenHospital morbidityHospital outcomesRenal functionBiventricular functionRenal perfusionVenous pressureTrends in In-Hospital Mortality, Length of Stay, Nonroutine Discharge, and Cost Among End-Stage Renal Disease Patients on Dialysis Hospitalized With Heart Failure (2001–2014)
Inampudi C, Akintoye E, Bengaluru Jayanna M, Asleh R, Briasouli A, Alvarez P, Briasoulis A. Trends in In-Hospital Mortality, Length of Stay, Nonroutine Discharge, and Cost Among End-Stage Renal Disease Patients on Dialysis Hospitalized With Heart Failure (2001–2014). Journal Of Cardiac Failure 2019, 25: 524-533. PMID: 30844441, DOI: 10.1016/j.cardfail.2019.02.020.Peer-Reviewed Original ResearchConceptsLength of stayEnd-stage renal disease patientsHF admissionsRenal disease patientsHospital mortalityNonroutine dischargeHeart failureESRD patientsDisease patientsStudy periodAnnual national ratesHF admission ratesPrevalence of comorbiditiesIn-Hospital MortalityNational Inpatient SampleCost of hospitalizationAnnual percentage changeYears of ageHF hospitalizationSecondary admissionsAdmission diagnosisComorbidity prevalencePeritoneal dialysisSubgroup analysisInpatient SampleTrends in utilization, mortality, major complications, and cost after total artificial heart implantation in the United States (2009-2015)
Briasoulis A, Akintoye E, Mohsen A, Inampudi C, Briasouli A, Asleh R, Alvarez P. Trends in utilization, mortality, major complications, and cost after total artificial heart implantation in the United States (2009-2015). Hellenic Journal Of Cardiology 2019, 61: 407-412. PMID: 30790715, DOI: 10.1016/j.hjc.2019.02.002.Peer-Reviewed Original ResearchConceptsLength of stayTotal artificial heartHospital mortalityHeart transplantationTAH implantationMajor complicationsLeft ventricular assist device implantationVentricular assist device implantationTotal artificial heart implantationComplex congenital heart diseaseStudy periodAcute kidney injuryAssist device implantationSame hospital staySevere biventricular failureDisposition of patientsNational Inpatient SampleTime of dischargeContinuous-flow LVADCost of hospitalizationArtificial heart implantationCongenital heart diseaseHospital complicationsMajor bleedingBiventricular failureTrends and Outcomes of Infective Endocarditis in Adults With Tetralogy of Fallot: A Review of the National Inpatient Sample Database
Egbe A, Vallabhajosyula S, Akintoye E, Connolly H. Trends and Outcomes of Infective Endocarditis in Adults With Tetralogy of Fallot: A Review of the National Inpatient Sample Database. Canadian Journal Of Cardiology 2019, 35: 721-726. PMID: 31151707, DOI: 10.1016/j.cjca.2019.02.006.Peer-Reviewed Original ResearchConceptsHealth care resource utilizationTetralogy of FallotProsthetic valve implantationNational Inpatient SampleCongenital heart diseaseHospital mortalityValve implantationInfective endocarditisHeart diseaseRisk factorsTOF patientsInflation-adjusted hospitalization costsNational Inpatient Sample databaseCyanotic congenital heart diseaseIncidence of endocarditisLength of stayPacemaker/defibrillatorLow socioeconomic classPopulation-based riskHospital dischargeSecondary outcomesPrimary outcomeHospitalization costsBlack raceInpatient SamplePredictors of Hospital Cost After Transcatheter Aortic Valve Implantation in the United States: From the Nationwide Inpatient Sample Database
Ando T, Adegbala O, Villablanca P, Akintoye E, Ashraf S, Briasoulis A, Telila T, Takagi H, Grines C, Schreiber T, Bhatt D, Afonso L. Predictors of Hospital Cost After Transcatheter Aortic Valve Implantation in the United States: From the Nationwide Inpatient Sample Database. The American Journal Of Cardiology 2019, 123: 1142-1148. PMID: 30658917, DOI: 10.1016/j.amjcard.2018.12.044.Peer-Reviewed Original ResearchMeSH KeywordsAged, 80 and overAortic Valve StenosisDatabases, FactualFemaleHospital CostsHospital MortalityHospitalizationHumansIncidenceInpatientsMalePatient Acceptance of Health CarePostoperative ComplicationsPropensity ScoreRisk FactorsTime FactorsTranscatheter Aortic Valve ReplacementUnited StatesConceptsTranscatheter aortic valve implantationNationwide Inpatient Sample databaseHigh-cost groupHigher hospitalization costsAortic valve implantationHospitalization costsValve implantationHospital costsSample databaseSurgical aortic valve replacementCost groupsHigher co-morbidity burdenAcute kidney injuryAcute respiratory failureAortic valve replacementPeripheral vascular diseaseCo-morbidity burdenCost of hospitalizationLength of stayMultivariable regression analysisLow-cost groupHigh incremental costPost-TAVITAVI hospitalizationsCardiogenic shock
2018
In‐hospital outcomes of transcatheter mitral valve repair with Mitraclip in patients with pulmonary hypertension: Insights from the National Inpatient Sample
Ahmed A, Akintoye E, Adegbala O, Yassin A, Subahi A, Bangura L, Abubakar H, Elder M, Shokr M, Afonso L. In‐hospital outcomes of transcatheter mitral valve repair with Mitraclip in patients with pulmonary hypertension: Insights from the National Inpatient Sample. Catheterization And Cardiovascular Interventions 2018, 94: e30-e36. PMID: 30506974, DOI: 10.1002/ccd.27997.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overCardiac CatheterizationClinical Decision-MakingDatabases, FactualFemaleHeart Valve ProsthesisHeart Valve Prosthesis ImplantationHospital MortalityHumansHypertension, PulmonaryMaleMiddle AgedMitral ValveMitral Valve InsufficiencyPatient SelectionPostoperative ComplicationsPrevalenceProsthesis DesignRecovery of FunctionRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeUnited StatesConceptsTranscatheter mitral valve repairNational Inpatient SamplePulmonary hypertensionMitral valve repairHospital outcomesValve repairInpatient SamplePre-existing pulmonary hypertensionPrevalence of PHPostoperative deep vein thrombosisAcute respiratory failureCohort of patientsDeep vein thrombosisMedian hospital costsHemorrhage requiring transfusionLength of stayPH groupCardiogenic shockPostoperative sepsisRespiratory failureHome dischargeInpatient mortalityPeriprocedural outcomesProhibitive riskPulmonary embolismComparison of In-Hospital Outcomes of Patients With-Versus-Without Ischemic Cardiomyopathy Undergoing Left Ventricular Assist Device Placement
Abubakar H, Subahi A, Adegbala O, Yassin A, Akintoye E, Abdulrahman A, Ahmed A, Alade A, Pahuja M, Afonso L. Comparison of In-Hospital Outcomes of Patients With-Versus-Without Ischemic Cardiomyopathy Undergoing Left Ventricular Assist Device Placement. The American Journal Of Cardiology 2018, 123: 414-418. PMID: 30545482, DOI: 10.1016/j.amjcard.2018.10.039.Peer-Reviewed Original ResearchConceptsVentricular assist device placementPostoperative myocardial infarctionLength of stayHospital mortalityVascular complicationsLVAD placementMyocardial infarctionEnd pointLeft ventricular assist device placementNationwide Inpatient Sample databaseST-segment myocardial infarctionDevice placementPeriprocedural vascular complicationsHeart failure etiologyIn-Hospital OutcomesPrimary end pointSecondary end pointsClinical end pointsHospital-level characteristicsCost of hospitalizationHemorrhage requiring transfusionMixed-effects logistic modelHospital outcomesFailure etiologyIschemic cardiomyopathyThe impact of atrial fibrillation on transcatheter mitral valve repair outcomes: A propensity‐matched analysis
Subahi A, Munir A, Abubakar H, Akintoye E, Yassin A, Adegbala O, Alraies M, Elder M, Mohamad T, Kaki A, Schreiber T. The impact of atrial fibrillation on transcatheter mitral valve repair outcomes: A propensity‐matched analysis. Journal Of Interventional Cardiology 2018, 31: 925-931. PMID: 30456770, DOI: 10.1111/joic.12568.Peer-Reviewed Original ResearchConceptsTranscatheter mitral valve repairAtrial fibrillationHospital outcomesTranscatheter Mitral Valve Repair OutcomesICD-9-CM diagnostic codesMitral valve repair outcomesNational Inpatient Sample registryNon-routine hospital dischargeImpact of AFPrevalence of AFPropensity score-matched analysisHigher AF burdenPropensity-matched analysisRepresentative United States sampleHospital-level characteristicsMitral valve repairCost of hospitalizationLength of stayHospital mortalityAF burdenHospital dischargePatient characteristicsAF patientsBaseline rhythmTMVR proceduresNational trends in Fontan operation and in-hospital outcomes in the USA
Akintoye E, Miranda W, Veldtman G, Connolly H, Egbe A. National trends in Fontan operation and in-hospital outcomes in the USA. Heart 2018, 105: 708. PMID: 30377261, DOI: 10.1136/heartjnl-2018-313680.Peer-Reviewed Original ResearchConceptsFontan operationHospital mortalityPostoperative complicationsClinical Modification procedure codesHypoplastic left heart syndromePostoperative cardiac complicationsCongenital heart disease diagnosisNationwide Inpatient SampleAcute care facilitiesLength of stayNumber of patientsDiseases-Ninth RevisionVolume of proceduresSignificant declineNumber of proceduresCardiac complicationsRespiratory complicationsHospital dischargeHospital outcomesPatient demographicsMedian ageHeart syndromeHospitalisation costsPatient populationSignificant changesEffect of Hospital Ownership on Outcomes After Left Ventricular Assist Device Implantation in the United States
Briasoulis A, Inampudi C, Akintoye E, Adegbala O, Bhama J, Alvarez P. Effect of Hospital Ownership on Outcomes After Left Ventricular Assist Device Implantation in the United States. The Annals Of Thoracic Surgery 2018, 107: 527-532. PMID: 30316859, DOI: 10.1016/j.athoracsur.2018.08.051.Peer-Reviewed Original Research