2019
The impact of safety‐net burden on in‐hospital outcomes after surgical aortic valve replacement
Ando T, Adegbala O, Akintoye E, Briasoulis A, Takagi H. The impact of safety‐net burden on in‐hospital outcomes after surgical aortic valve replacement. Journal Of Cardiac Surgery 2019, 34: 1178-1184. PMID: 31441545, DOI: 10.1111/jocs.14187.Peer-Reviewed Original ResearchConceptsSurgical aortic valve replacementSafety-net burdenAortic valve replacementSAVR outcomesValve replacementAcute kidney injuryMajor perioperative complicationsHospital-level characteristicsNationwide Inpatient SampleLength of staySafety-net hospitalNumber of admissionsHospital mortalityNonroutine dischargeValvular surgeryHospital outcomesHospital stayKidney injuryPerioperative complicationsDisadvantaged patientsInpatient SampleHospital costsUnadjusted modelsHospitalPatientsClinical and economic burden of heparin-induced thrombocytopenia in hospitalized patients undergoing percutaneous peripheral arterial interventions
Subahi A, Osman M, Adegbala O, Abubakar H, Kheiri B, Yassin A, Khalid M, Akintoye E, Eljack A, Osman K, Alkhouli M. Clinical and economic burden of heparin-induced thrombocytopenia in hospitalized patients undergoing percutaneous peripheral arterial interventions. Vascular 2019, 28: 81-86. PMID: 31382836, DOI: 10.1177/1708538119868615.Peer-Reviewed Original ResearchConceptsVenous thrombosis/pulmonary embolismAcute kidney injuryKidney injuryIschemic strokePulmonary embolismHigh riskDeep venous thrombosis/pulmonary embolismPercutaneous peripheral arterial interventionsICD-9-CM codesHospital mortality differenceProlonged hospital stayHospital-level characteristicsPeripheral arterial interventionsNational Inpatient SampleHospital outcomesHospital stayIntervention patientsAbsence of heparinBaseline characteristicsHome dischargeLonger hospitalizationArterial interventionsHospitalized patientsInpatient SampleThrombocytopeniaCharacteristics and Outcomes of Patients with Cardiogenic Shock Complicated by Acute Kidney Injury Requiring Hemodialysis
Inampudi C, Adegbala O, Akintoye E, Alvarez P, Briasoulis A. Characteristics and Outcomes of Patients with Cardiogenic Shock Complicated by Acute Kidney Injury Requiring Hemodialysis. The Journal Of Heart And Lung Transplantation 2019, 38: s63. DOI: 10.1016/j.healun.2019.01.141.Peer-Reviewed Original ResearchLength of stayCardiogenic shockOutcomes of patientsHospital mortalityAcute Kidney Injury Requiring HemodialysisPre-existing chronic kidney diseasePropensity score-matched groupsHigher comorbidity burdenAcute kidney injuryChronic kidney diseaseRenal replacement therapyHospital-level characteristicsRenal venous pressureNational Inpatient SampleComorbidity burdenHospital morbidityHospital outcomesKidney injuryElixhauser scoreRenal functionBiventricular functionDiabetes mellitusRenal perfusionVenous pressureHospitalization costsCharacteristics and Outcomes of Patients With Cardiogenic Shock Utilizing Hemodialysis for Acute Kidney Injury
Adegbala O, Inampudi C, Adejumo A, Otuonye G, Akintoye E, Elsayed R, Williams K, Alvarez P, Afonso L, Briasoulis A. Characteristics and Outcomes of Patients With Cardiogenic Shock Utilizing Hemodialysis for Acute Kidney Injury. The American Journal Of Cardiology 2019, 123: 1816-1821. PMID: 30967283, DOI: 10.1016/j.amjcard.2019.02.038.Peer-Reviewed Original ResearchConceptsLength of stayAcute kidney injuryCardiogenic shockOutcomes of patientsHospital mortalityKidney injuryTemporary mechanical supportCause of CSPropensity score-matched groupsST-elevation myocardial infarctionMechanical circulatory support devicesHigher comorbidity burdenRenal replacement therapyElevation myocardial infarctionHospital-level characteristicsRenal venous pressureNational Inpatient SampleCirculatory support devicesComorbidity burdenHospital morbidityHospital outcomesRenal functionBiventricular functionRenal perfusionVenous pressure
2018
Clinical Impact of Diabetes Mellitus on Short-Term Outcomes andIn-Hospital Mortality of Cardiac Mechanical Support with Left Ventricular Assist Device (LVAD): A Retrospective Study from a National Database
Yassin A, Subahi A, Adegbala O, Abubakar H, Akintoye E, Ahmed A, Ismail A, Elhag A, Kambal A, Alade A, Shokr M, Weinberger J, Levine D, Afonso L. Clinical Impact of Diabetes Mellitus on Short-Term Outcomes andIn-Hospital Mortality of Cardiac Mechanical Support with Left Ventricular Assist Device (LVAD): A Retrospective Study from a National Database. Cardiovascular Revascularization Medicine 2018, 20: 883-886. PMID: 30578171, DOI: 10.1016/j.carrev.2018.12.011.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedDatabases, FactualDiabetes MellitusFemaleHeart FailureHeart-Assist DevicesHospital MortalityHumansMaleMiddle AgedProsthesis DesignProsthesis ImplantationRecovery of FunctionRegistriesRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeUnited StatesVentricular Dysfunction, LeftVentricular Function, LeftConceptsLeft ventricular assist deviceCardiac mechanical supportDiabetes mellitusCost of hospitalizationCardiac supportVentricular assist deviceHospital mortalityDiabetic patientsHeart failureClinical impactMultivariable logistic regression model analysisAssist deviceStage D heart failureAdvanced congestive heart failureNational Inpatient Sample databasePost-LVAD complicationsShort-term complicationsCongestive heart failureLogistic regression model analysisHospital-level characteristicsImpact of diabetesRegression model analysisInpatient mortalityLVAD implantationSecondary outcomesComparison of In-Hospital Outcomes of Patients With-Versus-Without Ischemic Cardiomyopathy Undergoing Left Ventricular Assist Device Placement
Abubakar H, Subahi A, Adegbala O, Yassin A, Akintoye E, Abdulrahman A, Ahmed A, Alade A, Pahuja M, Afonso L. Comparison of In-Hospital Outcomes of Patients With-Versus-Without Ischemic Cardiomyopathy Undergoing Left Ventricular Assist Device Placement. The American Journal Of Cardiology 2018, 123: 414-418. PMID: 30545482, DOI: 10.1016/j.amjcard.2018.10.039.Peer-Reviewed Original ResearchConceptsVentricular assist device placementPostoperative myocardial infarctionLength of stayHospital mortalityVascular complicationsLVAD placementMyocardial infarctionEnd pointLeft ventricular assist device placementNationwide Inpatient Sample databaseST-segment myocardial infarctionDevice placementPeriprocedural vascular complicationsHeart failure etiologyIn-Hospital OutcomesPrimary end pointSecondary end pointsClinical end pointsHospital-level characteristicsCost of hospitalizationHemorrhage requiring transfusionMixed-effects logistic modelHospital outcomesFailure etiologyIschemic cardiomyopathyThe impact of atrial fibrillation on transcatheter mitral valve repair outcomes: A propensity‐matched analysis
Subahi A, Munir A, Abubakar H, Akintoye E, Yassin A, Adegbala O, Alraies M, Elder M, Mohamad T, Kaki A, Schreiber T. The impact of atrial fibrillation on transcatheter mitral valve repair outcomes: A propensity‐matched analysis. Journal Of Interventional Cardiology 2018, 31: 925-931. PMID: 30456770, DOI: 10.1111/joic.12568.Peer-Reviewed Original ResearchConceptsTranscatheter mitral valve repairAtrial fibrillationHospital outcomesTranscatheter Mitral Valve Repair OutcomesICD-9-CM diagnostic codesMitral valve repair outcomesNational Inpatient Sample registryNon-routine hospital dischargeImpact of AFPrevalence of AFPropensity score-matched analysisHigher AF burdenPropensity-matched analysisRepresentative United States sampleHospital-level characteristicsMitral valve repairCost of hospitalizationLength of stayHospital mortalityAF burdenHospital dischargePatient characteristicsAF patientsBaseline rhythmTMVR proceduresFinancial Implications and Impact of Pre-existing Atrial Fibrillation on In-Hospital Outcomes in Patients Who Underwent Transcatheter Aortic Valve Implantation (from the National Inpatient Database)
Abubakar H, Yassin A, Akintoye E, Bakhit K, Pahuja M, Shokr M, Lieberman R, Afonso L. Financial Implications and Impact of Pre-existing Atrial Fibrillation on In-Hospital Outcomes in Patients Who Underwent Transcatheter Aortic Valve Implantation (from the National Inpatient Database). The American Journal Of Cardiology 2018, 121: 1587-1592. PMID: 29622287, DOI: 10.1016/j.amjcard.2018.02.052.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAortic Valve StenosisArrhythmias, CardiacAtrial FibrillationCardiac Pacing, ArtificialCardiac TamponadeComorbidityDatabases, FactualFemaleHeart ArrestHeart FailureHospital CostsHospital MortalityHumansLength of StayLinear ModelsLogistic ModelsMaleMyocardial InfarctionPacemaker, ArtificialPericardial EffusionPostoperative ComplicationsPostoperative HemorrhageStrokeTranscatheter Aortic Valve ReplacementUnited StatesConceptsTranscatheter aortic valve implantationPre-existing atrial fibrillationLength of stayPeriprocedural cardiac complicationsAortic valve implantationAtrial fibrillationCost of hospitalizationCardiac complicationsHospital mortalityEnd pointValve implantationLonger hospital LOSUnderwent Transcatheter Aortic Valve ImplantationPre-existing AFHospital LOSIncidence of AFLonger LOSNationwide Inpatient Sample databaseIn-Hospital OutcomesPrimary end pointSecondary end pointsClinical end pointsHospital-level characteristicsMixed-effects logistic modelTAVI patients
2017
Incidence and Outcomes of Heparin-Induced Thrombocytopenia in Patients Undergoing Transcatheter Aortic Valve Replacement
Telila T, Akintoye E, Ando T, Merid O, Mallikethi-Reddy S, Briasoulis A, Grines C, Afonso L. Incidence and Outcomes of Heparin-Induced Thrombocytopenia in Patients Undergoing Transcatheter Aortic Valve Replacement. The American Journal Of Cardiology 2017, 120: 300-303. PMID: 28576265, DOI: 10.1016/j.amjcard.2017.04.028.Peer-Reviewed Original ResearchMeSH KeywordsAged, 80 and overAnticoagulantsAortic Valve StenosisFemaleHeparinHospital MortalityHumansIncidenceKaplan-Meier EstimateMalePostoperative ComplicationsPrognosisRetrospective StudiesRisk FactorsSurvival RateThrombocytopeniaThromboembolismTranscatheter Aortic Valve ReplacementTreatment OutcomeUnited StatesConceptsVenous thrombosis/pulmonary embolismAcute kidney injuryHospital-level characteristicsHospital stayHospital mortalityKidney injuryPulmonary embolismHospital costsTranscatheter aortic valve replacementNationwide Inpatient Sample databaseOutcomes of HITPerioperative thromboembolic complicationsLonger hospital stayOutcomes of patientsAortic valve replacementHeparin-Induced ThrombocytopeniaMedian hospital costsImpact of HITTAVR groupCumulative incidenceInpatient mortalitySecondary outcomesThromboembolic complicationsValve replacementCardiac surgery