2020
Aortic Valve Replacement for Severe Aortic Stenosis Before and During the Era of Transcatheter Aortic Valve Implantation
Akintoye E, Ando T, Sandio A, Adegbala O, Salih M, Zubairu J, Oseni A, Sistla P, Alqasrawi M, Egbe A, Mentias A, Afonso L, Briasoulis A, Panaich S, Desai M. Aortic Valve Replacement for Severe Aortic Stenosis Before and During the Era of Transcatheter Aortic Valve Implantation. The American Journal Of Cardiology 2020, 126: 73-81. PMID: 32336533, DOI: 10.1016/j.amjcard.2020.03.038.Peer-Reviewed Original ResearchConceptsSevere aortic stenosisAortic valve replacementNational Inpatient SampleTAVI eraAortic stenosisMean annual changeValve replacementFavorable short-term outcomesTranscatheter aortic valve replacementTranscatheter aortic valve implantationRate of AVRAcute kidney injuryRate of strokeAortic valve implantationShort-term outcomesRisk-adjusted ratesHospital mortalityPre-TAVIHospital outcomesKidney injuryHome dischargeHospital dischargePacemaker implantationValve implantationMedian length
2019
The impact of safety‐net burden on in‐hospital outcomes after surgical aortic valve replacement
Ando T, Adegbala O, Akintoye E, Briasoulis A, Takagi H. The impact of safety‐net burden on in‐hospital outcomes after surgical aortic valve replacement. Journal Of Cardiac Surgery 2019, 34: 1178-1184. PMID: 31441545, DOI: 10.1111/jocs.14187.Peer-Reviewed Original ResearchConceptsSurgical aortic valve replacementSafety-net burdenAortic valve replacementSAVR outcomesValve replacementAcute kidney injuryMajor perioperative complicationsHospital-level characteristicsNationwide Inpatient SampleLength of staySafety-net hospitalNumber of admissionsHospital mortalityNonroutine dischargeValvular surgeryHospital outcomesHospital stayKidney injuryPerioperative complicationsDisadvantaged patientsInpatient SampleHospital costsUnadjusted modelsHospitalPatientsIncidence and predictors of readmissions to non-index hospitals after transcatheter aortic valve replacement and the impact on in-hospital outcomes: From the nationwide readmission database
Ando T, Adegbala O, Villablanca P, Akintoye E, Ashraf S, Shokr M, Siddiqui F, Takagi H, Grines C, Afonso L, Briasoulis A. Incidence and predictors of readmissions to non-index hospitals after transcatheter aortic valve replacement and the impact on in-hospital outcomes: From the nationwide readmission database. International Journal Of Cardiology 2019, 292: 50-55. PMID: 31053244, DOI: 10.1016/j.ijcard.2019.04.056.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve replacementNon-index hospitalsNon-index hospital readmissionsNon-index readmissionsAortic valve replacementNationwide Readmissions DatabaseHospital mortalityIndex hospitalHospital outcomesValve replacementHospital readmissionEndovascular transcatheter aortic valve replacementMetropolitan non-teaching hospitalsMultivariable logistic regression analysisAcute kidney injuryPredictors of readmissionAcute myocardial infarctionLength of stayLogistic regression analysisNon-teaching hospitalsElective readmissionsTAVR recipientsKidney injuryPacemaker placementHealthcare utilizationINCIDENCE, PREDICTORS, AND IMPACT OF READMISSIONS TO NON-INDEX HOSPITALS AFTER TRANSCATHETER AORTIC VALVE REPLACEMENT ON IN-HOSPITAL OUTCOMES: FROM THE NATIONWIDE READMISSION DATABASE
Ando T, Adegbala O, Villablanca P, Akintoye E, Ashraf S, Shokr M, Siddiqui F, Briasoulis A, Takagi H, Grines C, Afonso L. INCIDENCE, PREDICTORS, AND IMPACT OF READMISSIONS TO NON-INDEX HOSPITALS AFTER TRANSCATHETER AORTIC VALVE REPLACEMENT ON IN-HOSPITAL OUTCOMES: FROM THE NATIONWIDE READMISSION DATABASE. Journal Of The American College Of Cardiology 2019, 73: 1199. DOI: 10.1016/s0735-1097(19)31806-6.Peer-Reviewed Original ResearchPredictors of Hospital Cost After Transcatheter Aortic Valve Implantation in the United States: From the Nationwide Inpatient Sample Database
Ando T, Adegbala O, Villablanca P, Akintoye E, Ashraf S, Briasoulis A, Telila T, Takagi H, Grines C, Schreiber T, Bhatt D, Afonso L. Predictors of Hospital Cost After Transcatheter Aortic Valve Implantation in the United States: From the Nationwide Inpatient Sample Database. The American Journal Of Cardiology 2019, 123: 1142-1148. PMID: 30658917, DOI: 10.1016/j.amjcard.2018.12.044.Peer-Reviewed Original ResearchMeSH KeywordsAged, 80 and overAortic Valve StenosisDatabases, FactualFemaleHospital CostsHospital MortalityHospitalizationHumansIncidenceInpatientsMalePatient Acceptance of Health CarePostoperative ComplicationsPropensity ScoreRisk FactorsTime FactorsTranscatheter Aortic Valve ReplacementUnited StatesConceptsTranscatheter aortic valve implantationNationwide Inpatient Sample databaseHigh-cost groupHigher hospitalization costsAortic valve implantationHospitalization costsValve implantationHospital costsSample databaseSurgical aortic valve replacementCost groupsHigher co-morbidity burdenAcute kidney injuryAcute respiratory failureAortic valve replacementPeripheral vascular diseaseCo-morbidity burdenCost of hospitalizationLength of stayMultivariable regression analysisLow-cost groupHigh incremental costPost-TAVITAVI hospitalizationsCardiogenic shock
2018
Incidence, Trends, and Predictors of Palliative Care Consultation After Aortic Valve Replacement in the United States
Ando T, Adegbala O, Uemura T, Akintoye E, Ashraf S, Briasoulis A, Takagi H, Afonso L. Incidence, Trends, and Predictors of Palliative Care Consultation After Aortic Valve Replacement in the United States. Journal Of Palliative Care 2018, 34: 111-117. PMID: 30587081, DOI: 10.1177/0825859718819433.Peer-Reviewed Original ResearchConceptsSurgical aortic valve replacementTranscatheter aortic valve replacementAortic valve replacementPC referral rateAdjusted odds ratioPC consultPC referralValve replacementIndex hospitalizationPC consultationReferral ratesTransapical transcatheter aortic valve replacementAortic valve replacement patientsNationwide Inpatient Sample databaseValve replacement patientsPalliative care consultPalliative care consultationMultivariable regression analysisCare consultTAVR cohortAcceptable morbidityInpatient mortalityReplacement patientsElectrolyte derangementsNIS databaseTCT-570 In-Hospital Outcomes of Transcatheter Aortic Valve Replacement After Non-Elective Admission in Comparison with Elective Admission
Ando T, Adegbala O, Villablanca P, Akintoye E, Ashraf S, Shokr M, Pahuja M, Briasoulis A, Takagi H, Grines C, Afonso L, Schreiber T. TCT-570 In-Hospital Outcomes of Transcatheter Aortic Valve Replacement After Non-Elective Admission in Comparison with Elective Admission. Journal Of The American College Of Cardiology 2018, 72: b228. DOI: 10.1016/j.jacc.2018.08.1761.Peer-Reviewed Original ResearchOutcomes and Effects of Hepatic Cirrhosis in Patients Who Underwent Transcatheter Aortic Valve Implantation
Yassin A, Subahi A, Abubakar H, Akintoye E, Alhusain R, Adegbala O, Ahmed A, Elmoughrabi A, Subahi E, Pahuja M, Sahlieh A, Elder M, Kaki A, Schreiber T, Mohamad T. Outcomes and Effects of Hepatic Cirrhosis in Patients Who Underwent Transcatheter Aortic Valve Implantation. The American Journal Of Cardiology 2018, 122: 455-460. PMID: 30041889, DOI: 10.1016/j.amjcard.2018.04.013.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve implantationAortic valve implantationLiver cirrhosisCirrhotic patientsValve implantationUnderwent Transcatheter Aortic Valve ImplantationNational Inpatient Sample databasePropensity score-matched analysisNonroutine hospital dischargeSevere aortic stenosisAortic valve replacementReasonable therapeutic optionCost of hospitalizationHospital mortalityHospital stayVascular complicationsHospital dischargeInpatient mortalitySecondary outcomesValve replacementAortic stenosisPacemaker implantationPrimary outcomeProcedural complicationsClinical outcomesClinical End Points of Transcatheter Aortic Valve Implantation Compared With Surgical Aortic Valve Replacement in Patients <65 Years of Age (From the National Inpatient Sample Database)
Ando T, Akintoye E, Holmes A, Briasoulis A, Pahuja M, Takagi H, Schreiber T, Grines C, Afonso L. Clinical End Points of Transcatheter Aortic Valve Implantation Compared With Surgical Aortic Valve Replacement in Patients <65 Years of Age (From the National Inpatient Sample Database). The American Journal Of Cardiology 2018, 122: 279-283. PMID: 29880287, DOI: 10.1016/j.amjcard.2018.03.356.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAortic ValveAortic Valve StenosisCause of DeathFemaleFollow-Up StudiesHospital MortalityHumansIncidenceInpatientsLength of StayMaleMiddle AgedPostoperative ComplicationsPropensity ScoreRegistriesRetrospective StudiesRisk AssessmentRisk FactorsSurvival RateTime FactorsTranscatheter Aortic Valve ReplacementUnited StatesYoung AdultConceptsSurgical aortic valve replacementTranscatheter aortic valve implantationAortic valve replacementShorter hospital stayAortic valve implantationHospital mortalityHospital stayValve replacementValve implantationNational Inpatient Sample databaseSafe alternativeAcute kidney injuryOlder patient populationClinical end pointsAcute myocardial infarctionPropensity score analysisYears of agePostprocedure strokeKidney injuryValve surgeryVascular complicationsMajor complicationsPacemaker implantationPatient populationMyocardial infarctionIs Transcatheter Aortic Valve Replacement Better Than Surgical Aortic Valve Replacement in Patients With Chronic Obstructive Pulmonary Disease? A Nationwide Inpatient Sample Analysis
Ando T, Adegbala O, Akintoye E, Ashraf S, Pahuja M, Briasoulis A, Takagi H, Grines C, Afonso L, Schreiber T. Is Transcatheter Aortic Valve Replacement Better Than Surgical Aortic Valve Replacement in Patients With Chronic Obstructive Pulmonary Disease? A Nationwide Inpatient Sample Analysis. Journal Of The American Heart Association 2018, 7: e008408. PMID: 29606641, PMCID: PMC5907603, DOI: 10.1161/jaha.117.008408.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAortic ValveAortic Valve StenosisCost SavingsCost-Benefit AnalysisDatabases, FactualFemaleHealth StatusHeart Valve Prosthesis ImplantationHospital CostsHospital MortalityHumansInpatientsLength of StayMaleMiddle AgedPostoperative ComplicationsPulmonary Disease, Chronic ObstructiveRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTranscatheter Aortic Valve ReplacementTreatment OutcomeUnited StatesConceptsTranscatheter aortic valve replacementAortic valve replacementValve replacementCOPD patientsChronic obstructive pulmonary disease patientsAortic valve replacement resultsNationwide Inpatient Sample AnalysisSurgical aortic valve replacementObstructive pulmonary disease patientsChronic obstructive pulmonary diseaseNationwide Inpatient Sample databaseRespiratory-related complicationsAcute kidney injuryAcute respiratory failurePropensity-matched cohortPulmonary disease patientsNoninvasive mechanical ventilationObstructive pulmonary diseaseAcute myocardial infarctionRespiratory related complicationsHospital mortalitySAVR patientsHospital stayKidney injuryRespiratory failure
2017
Hospital outcomes of transcatheter versus surgical aortic valve replacement in female in the United States
Ando T, Akintoye E, Telila T, Briasoulis A, Takagi H, Schreiber T, Afonso L, Grines C. Hospital outcomes of transcatheter versus surgical aortic valve replacement in female in the United States. Catheterization And Cardiovascular Interventions 2017, 91: 813-819. PMID: 28990736, DOI: 10.1002/ccd.27362.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAortic ValveAortic Valve StenosisComorbidityCost SavingsCost-Benefit AnalysisDatabases, FactualExtracorporeal Membrane OxygenationFemaleHeart Valve Prosthesis ImplantationHospital CostsHospital MortalityHumansMiddle AgedPostoperative ComplicationsRisk AssessmentRisk FactorsSex FactorsTime FactorsTranscatheter Aortic Valve ReplacementTreatment OutcomeUnited StatesConceptsSurgical aortic valve replacementTranscatheter aortic valve replacementAortic valve replacementExtracorporeal membrane oxygenationTAVR patientsValve replacementPrimary endpointCardiac surgeryMembrane oxygenationFemale patientsMyocardial infarctionOdds ratioNationwide Inpatient Sample databaseRisk of needAcute kidney injuryNew pacemaker implantationNonfatal myocardial infarctionConcomitant cardiac surgeryPerioperative cardiac arrestMedian hospital costsAcute myocardial infarctionLength of stayPropensity score analysisHospital mortalityNonroutine dischargeHospital teaching status and trascatheter aortic valve replacement outcomes in the United States: Analysis of the national inpatient sample
Telila T, Akintoye E, Ando T, Merid O, Palla M, Mallikethi‐Reddy S, Briasoulis A, Grines C, Afonso L. Hospital teaching status and trascatheter aortic valve replacement outcomes in the United States: Analysis of the national inpatient sample. Catheterization And Cardiovascular Interventions 2017, 90: 1200-1205. PMID: 28795480, DOI: 10.1002/ccd.27236.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overChi-Square DistributionDatabases, FactualFemaleHealthcare DisparitiesHospital CostsHospital MortalityHospitals, TeachingHumansLength of StayLinear ModelsLogistic ModelsMaleMultivariate AnalysisOdds RatioPostoperative ComplicationsProcess Assessment, Health CareRegistriesRisk FactorsTime FactorsTranscatheter Aortic Valve ReplacementTreatment OutcomeUnited StatesConceptsTranscatheter aortic valve replacementAcute kidney injuryNational Inpatient SampleHospital teaching statusHospital mortalityTeaching statusInpatient SampleMechanical circulatory support devicesAortic valve replacementProcedure-related complicationsShort-term outcomesMechanical circulatory supportLength of stayCirculatory support devicesICD-9 codingHospital stayKidney injurySecondary outcomesValve replacementPrimary outcomeTAVR proceduresClinical outcomesCirculatory supportMean agePatient outcomesComparison of In-Hospital Outcomes of Transcatheter Aortic Valve Implantation Versus Surgical Aortic Valve Replacement in Obese (Body Mass Index ≥ 30 Kg/M2) Patients
Ando T, Akintoye E, Trehan N, Telila T, Briasoulis A, Takagi H, Grines C, Afonso L. Comparison of In-Hospital Outcomes of Transcatheter Aortic Valve Implantation Versus Surgical Aortic Valve Replacement in Obese (Body Mass Index ≥ 30 Kg/M2) Patients. The American Journal Of Cardiology 2017, 120: 1858-1862. PMID: 28860018, DOI: 10.1016/j.amjcard.2017.07.098.Peer-Reviewed Original ResearchMeSH KeywordsAgedAortic ValveAortic Valve StenosisBody Mass IndexComorbidityFemaleFollow-Up StudiesHospital MortalityHumansIncidenceInpatientsMaleObesityPostoperative ComplicationsPrevalencePrognosisPropensity ScoreRisk AssessmentRisk FactorsSurvival RateTime FactorsTranscatheter Aortic Valve ReplacementUnited StatesConceptsTranscatheter aortic valve implantationSurgical aortic valve replacementAortic valve replacementTAVI patientsNonroutine dischargeObese patientsValve replacementTranscatheter Aortic Valve Implantation Versus Surgical Aortic Valve ReplacementNationwide Inpatient Sample databaseHigher co-morbidity burdenCertain perioperative complicationsAcute kidney injuryIn-Hospital OutcomesShorter hospital stayAortic valve implantationCo-morbidity burdenMedian hospital costsAcute myocardial infarctionLength of stayCharlson scoreDeyo's modificationHospital mortalityCardiac complicationsHospital stayKidney injuryRole of diastolic function indices in the risk stratification of patients with mixed aortic valve disease
Egbe A, Khan A, Boler A, Said S, Geske J, Miranda W, Akintoye E, Connolly H, Warnes C, Oh J. Role of diastolic function indices in the risk stratification of patients with mixed aortic valve disease. European Heart Journal - Cardiovascular Imaging 2017, 19: 668-674. PMID: 28655164, DOI: 10.1093/ehjci/jex148.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAnalysis of VarianceAortic Valve InsufficiencyAortic Valve StenosisAsymptomatic DiseasesCohort StudiesConfidence IntervalsDiastoleEchocardiographyFemaleHumansMaleMiddle AgedMonitoring, PhysiologicPredictive Value of TestsPrognosisRetrospective StudiesRisk AssessmentSex FactorsStroke VolumeSurvival RateUnited StatesConceptsAortic valve replacementCardiovascular adverse eventsRelative wall thicknessMixed aortic valve diseaseDiastolic function indicesAortic valve diseaseCardiac deathRisk stratificationValve diseaseFunction IndexHigh-risk patient subsetsPost-operative risk stratificationSevere left ventricular dysfunctionAtrial volume indexHeart failure hospitalizationTricuspid regurgitation velocityEarly diastolic velocityLeft ventricular dysfunctionMultivariable risk factorsAsymptomatic patientsCardiovascular morbidityFailure hospitalizationPrimary endpointSecondary endpointsVentricular dysfunctionIncidence and Outcomes of Heparin-Induced Thrombocytopenia in Patients Undergoing Transcatheter Aortic Valve Replacement
Telila T, Akintoye E, Ando T, Merid O, Mallikethi-Reddy S, Briasoulis A, Grines C, Afonso L. Incidence and Outcomes of Heparin-Induced Thrombocytopenia in Patients Undergoing Transcatheter Aortic Valve Replacement. The American Journal Of Cardiology 2017, 120: 300-303. PMID: 28576265, DOI: 10.1016/j.amjcard.2017.04.028.Peer-Reviewed Original ResearchMeSH KeywordsAged, 80 and overAnticoagulantsAortic Valve StenosisFemaleHeparinHospital MortalityHumansIncidenceKaplan-Meier EstimateMalePostoperative ComplicationsPrognosisRetrospective StudiesRisk FactorsSurvival RateThrombocytopeniaThromboembolismTranscatheter Aortic Valve ReplacementTreatment OutcomeUnited StatesConceptsVenous thrombosis/pulmonary embolismAcute kidney injuryHospital-level characteristicsHospital stayHospital mortalityKidney injuryPulmonary embolismHospital costsTranscatheter aortic valve replacementNationwide Inpatient Sample databaseOutcomes of HITPerioperative thromboembolic complicationsLonger hospital stayOutcomes of patientsAortic valve replacementHeparin-Induced ThrombocytopeniaMedian hospital costsImpact of HITTAVR groupCumulative incidenceInpatient mortalitySecondary outcomesThromboembolic complicationsValve replacementCardiac surgeryTRANSCATHETER VERSUS SURGICAL AORTIC VALVE REPLACEMENT IN DIABETES MELLITUS: FROM THE NATIONWIDE INPATIENT SAMPLE
Ando T, Akintoye E, Telila T, Briasoulis A, Takagi H, Slovut D, Schreiber T, Grines C, Afonso L. TRANSCATHETER VERSUS SURGICAL AORTIC VALVE REPLACEMENT IN DIABETES MELLITUS: FROM THE NATIONWIDE INPATIENT SAMPLE. Journal Of The American College Of Cardiology 2017, 69: 1310. DOI: 10.1016/s0735-1097(17)34699-5.Peer-Reviewed Original ResearchAortic valve replacementNationwide Inpatient SampleValve replacementDiabetes mellitusInpatient SampleMellitusTrends in Vascular Complications in High-Risk Patients Following Transcatheter Aortic Valve Replacement in the United States
Ando T, Akintoye E, Telila T, Briasoulis A, Takagi H, Grines C, Afonso L. Trends in Vascular Complications in High-Risk Patients Following Transcatheter Aortic Valve Replacement in the United States. The American Journal Of Cardiology 2017, 119: 1433-1437. PMID: 28256249, DOI: 10.1016/j.amjcard.2017.01.028.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAged, 80 and overAortic Valve StenosisComorbidityDiabetes MellitusFemaleHospital Bed CapacityHospitalsHospitals, RuralHospitals, TeachingHospitals, UrbanHumansMalePeripheral Vascular DiseasesPostoperative ComplicationsRisk FactorsSex FactorsTranscatheter Aortic Valve ReplacementUnited StatesVascular DiseasesConceptsTranscatheter aortic valve replacementHigh-risk groupAortic valve replacementHigh-risk patientsVascular complicationsVC rateValve replacementHigh riskPeripheral vascular disease patientsOverall populationNationwide Inpatient Sample databaseHigh-risk cohortVascular disease patientsContinuous longitudinal monitoringTAVR patientsCenter experienceDiabetes mellitusDisease patientsWorse outcomesInternational ClassificationPatientsSample databaseLongitudinal monitoringSignificant decreaseStatistical significanceComparison of Hospital Outcome of Transcatheter Versus Surgical Aortic Valve Replacement in Patients With Diabetes Mellitus (from the Nationwide Inpatient Sample)
Ando T, Akintoye E, Telila T, Briasoulis A, Takagi H, Slovut D, Schreiber T, Grines C, Afonso L. Comparison of Hospital Outcome of Transcatheter Versus Surgical Aortic Valve Replacement in Patients With Diabetes Mellitus (from the Nationwide Inpatient Sample). The American Journal Of Cardiology 2017, 119: 1250-1254. PMID: 28219665, DOI: 10.1016/j.amjcard.2016.12.026.Peer-Reviewed Original ResearchMeSH KeywordsAcute Kidney InjuryAgedAged, 80 and overBlood TransfusionDatabases, FactualDiabetes MellitusExtracorporeal Membrane OxygenationFemaleHeart Valve Prosthesis ImplantationHospital CostsHospital MortalityHumansLength of StayMaleMyocardial InfarctionPacemaker, ArtificialPostoperative ComplicationsSepsisTranscatheter Aortic Valve ReplacementUnited StatesConceptsSurgical aortic valve replacementTranscatheter aortic valve replacementAortic valve replacementTAVR patientsValve replacementDM patientsHospital outcomesOdds ratioOutcomes of TAVRTranscatheter Versus Surgical Aortic Valve ReplacementNationwide Inpatient Sample databasePrimary end pointNew pacemaker implantationDiabetes mellitus patientsMean hospitalization costAcute myocardial infarctionLength of staySAVR patientsSAVR proceduresCardiac complicationsCause mortalityPerioperative complicationsPostoperative sepsisRespiratory complicationsVascular complications