Meta-Analysis Comparing Catheter-Directed Thrombolysis Versus Systemic Anticoagulation Alone for Submassive Pulmonary Embolism
Ismayl M, Machanahalli Balakrishna A, Aboeata A, Gupta T, Young M, Altin S, Aronow H, Goldsweig A. Meta-Analysis Comparing Catheter-Directed Thrombolysis Versus Systemic Anticoagulation Alone for Submassive Pulmonary Embolism. The American Journal Of Cardiology 2022, 178: 154-162. PMID: 35778309, DOI: 10.1016/j.amjcard.2022.06.004.Peer-Reviewed Original ResearchConceptsSubmassive pulmonary embolismSystemic anticoagulationMinor bleedingPulmonary embolismBlood transfusionRisk ratioSimilar bleeding ratesRight ventricular dysfunctionFirst-line therapyConfidence intervalsRandom-effects modelHospital mortalityMajor bleedingHemodynamic instabilityVentricular dysfunctionOptimal therapyBleeding rateIndependent reviewersSystematic reviewBleedingMortalityPatientsGoogle ScholarAnticoagulationTransfusionSex Differences in Peripheral Artery Disease
Pabon M, Cheng S, Altin S, Sethi S, Nelson M, Moreau K, Hamburg N, Hess C. Sex Differences in Peripheral Artery Disease. Circulation Research 2022, 130: 496-511. PMID: 35175843, PMCID: PMC8919803, DOI: 10.1161/circresaha.121.320702.Peer-Reviewed Original ResearchConceptsPeripheral artery diseaseArtery diseaseManagement of PADSuch sex-based differencesNontraditional risk factorsSex differencesLack of diagnosisSex-based differencesImportant sex differencesIschemic cardiovascularPAD prevalenceVascular stressorSubstantial morbidityClinical presentationClinical manifestationsRisk factorsPrevalent conditionLimb eventsOverall populationVascular substratesDiseaseSex variationWomenCurrent knowledgeManifestations