2019
A Pilot Study of a Standardized Smoking Cessation Intervention for Patients with Vascular Disease
Rajaee S, Holder T, Indes JE, Muhs B, Sarac T, Sumpio B, Toll BA, Ochoa Chaar CI. A Pilot Study of a Standardized Smoking Cessation Intervention for Patients with Vascular Disease. Annals Of Vascular Surgery 2019, 61: 91-99.e3. PMID: 31449932, DOI: 10.1016/j.avsg.2019.06.017.Peer-Reviewed Original ResearchMeSH KeywordsAneurysmCardiovascular AgentsCholinergic AgentsConnecticutEndovascular ProceduresFemaleHumansMaleMiddle AgedNicotinePatient Education as TopicPeripheral Arterial DiseasePilot ProjectsRisk FactorsRisk Reduction BehaviorSmokersSmokingSmoking CessationTime FactorsTobacco Use Cessation DevicesTransdermal PatchTreatment OutcomeVascular Surgical ProceduresConceptsSmoking cessation interventionIntervention groupSurgery providersPrimary outcomeCessation interventionsExact testBrief smoking cessation counselingCurrent smoking cessation practicesCarbon monoxide breath testingSmoking cessation counselingSmoking cessation practicesVascular surgery serviceSmoking cessation counseling sessionsTertiary care centerFree nicotine patchesSmoking cessation programOpen surgical proceduresOutpatient smoking cessation programFisher's exact testCessation counselingVascular complicationsStandard careNicotine patchNicotine replacementVascular patientsHigher Inpatient Mortality for Women after Intervention for Lifestyle Limiting Claudication
Miller SM, Sumpio BJ, Miller MS, Erben Y, Cordova AC, Sumpio BE. Higher Inpatient Mortality for Women after Intervention for Lifestyle Limiting Claudication. Annals Of Vascular Surgery 2019, 58: 54-62. PMID: 30910650, DOI: 10.1016/j.avsg.2019.01.006.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedComorbidityCritical IllnessDatabases, FactualEndovascular ProceduresFemaleHealth Status DisparitiesHospital MortalityHumansIntermittent ClaudicationIschemiaMalePatient AdmissionPeripheral Arterial DiseaseRisk AssessmentRisk FactorsSex FactorsTime FactorsTreatment OutcomeUnited StatesVascular Surgical ProceduresConceptsLifestyle-limiting claudicationHigher inpatient mortalityCritical limb ischemiaPeripheral artery diseaseInpatient mortalitySex-related differencesVascular interventionsEV interventionsArtery diseaseChronic obstructive pulmonary diseaseRegression analysisChronic renal failureObstructive pulmonary diseaseOpen surgical repairCoronary artery diseaseNationwide Inpatient SampleLogistic regression analysisChi-squared testLimb ischemiaRenal failureIndependent predictorsOpen repairPulmonary diseaseSurgical repairTreatment guidelines
2018
A survey of vascular specialists’ practice patterns of inferior vena cava filter placement and retrieval
Brahmandam A, Skrip L, Sumpio B, Indes J, Dardik A, Sarac T, Rectenwald J, Chaar CIO. A survey of vascular specialists’ practice patterns of inferior vena cava filter placement and retrieval. Vascular 2018, 27: 291-298. PMID: 30501583, DOI: 10.1177/1708538118815394.Peer-Reviewed Original ResearchMeSH KeywordsAttitude of Health PersonnelDevice RemovalHealth Care SurveysHealth Knowledge, Attitudes, PracticeHospitals, High-VolumeHospitals, Low-VolumeHumansPractice Patterns, Physicians'Prosthesis ImplantationRadiologistsRadiology, InterventionalSurgeonsTime FactorsUltrasonography, Doppler, DuplexUnited StatesVena Cava FiltersConceptsInferior vena cava filterVascular specialistsIVCF retrievalPractice patternsBronchoscopy forcepsRetrieval of IVCFTemporary inferior vena cava filterPermanent inferior vena cava filterInferior vena cava filter placementVena cava filter placementRetrievable inferior vena cava filtersLaser sheathLowest renal veinTertiary care centerCava filter placementVena cava filtersMajority of respondersChi-square testTwo-sample t-testVenous duplexRenal veinCare centerFilter placementSocietal guidelinesLower extremitiesRegulation of Yes-Associated Protein by Laminar Flow
Chitragari G, Shalaby SY, Sumpio BJ, Kurita J, Sumpio BE. Regulation of Yes-Associated Protein by Laminar Flow. Annals Of Vascular Surgery 2018, 52: 183-191. PMID: 29758328, DOI: 10.1016/j.avsg.2018.03.002.Peer-Reviewed Original ResearchMeSH KeywordsAdaptor Proteins, Signal TransducingCell ShapeCells, CulturedCytoskeletonDown-RegulationHuman Umbilical Vein Endothelial CellsHumansMechanotransduction, CellularPhosphoproteinsPhosphorylationProteolysisPulsatile FlowRegional Blood FlowStress, MechanicalTime FactorsTranscription FactorsYAP-Signaling ProteinsConceptsHuman umbilical vein endothelial cellsTotal YAPExposure of HUVECsRelease of mediatorsYAP levelsSignificant decreaseUbiquitin-proteasome system inhibitorsUmbilical vein endothelial cellsEndothelial cell proliferationVein endothelial cellsVascular healthSystem inhibitorsYes-Associated ProteinDisease modulationIntimal hyperplasiaDisturbed flowEndothelial cellsBlood vesselsDisease statesPotential targetCell proliferationProteasome-independent mechanismExposureKey regulatorPYAPEndovascular interventions decrease length of hospitalization and are cost-effective in acute mesenteric ischemia
Erben Y, Protack CD, Jean RA, Sumpio BJ, Miller SM, Liu S, Trejo G, Sumpio BE. Endovascular interventions decrease length of hospitalization and are cost-effective in acute mesenteric ischemia. Journal Of Vascular Surgery 2018, 68: 459-469. PMID: 29459015, DOI: 10.1016/j.jvs.2017.11.078.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAcute Kidney InjuryAdolescentAdultAgedAged, 80 and overComorbidityCost SavingsCost-Benefit AnalysisDatabases, FactualEndovascular ProceduresFemaleHospital CostsHospital MortalityHumansLength of StayLinear ModelsLogistic ModelsMaleMesenteric IschemiaMesenteric Vascular OcclusionMiddle AgedMultivariate AnalysisOdds RatioPatient DischargePropensity ScoreProportional Hazards ModelsRetrospective StudiesRisk FactorsSplanchnic CirculationTime FactorsTreatment OutcomeUnited StatesVascular Surgical ProceduresYoung AdultConceptsAcute mesenteric ischemiaAcute kidney injuryEndovascular interventionHospital mortalityMesenteric ischemiaHospitalization costsOpen groupPropensity-adjusted logistic regression analysisTreatment of AMISevere Charlson Comorbidity IndexEnd pointCharlson Comorbidity IndexOpen surgical revascularizationPrimary end pointSecondary end pointsIncreased hazard ratioLength of hospitalizationMean hospitalization costNational Inpatient SampleCost of hospitalizationLogistic regression analysisSkilled nursing facilitiesLower mortality rateComorbidity indexHospital stayImproved mortality in treatment of patients with endovascular interventions for chronic mesenteric ischemia
Erben Y, Jean RA, Protack CD, Chiu AS, Liu S, Sumpio BJ, Miller SM, Sumpio BE. Improved mortality in treatment of patients with endovascular interventions for chronic mesenteric ischemia. Journal Of Vascular Surgery 2018, 67: 1805-1812. PMID: 29395425, DOI: 10.1016/j.jvs.2017.10.071.Peer-Reviewed Original ResearchConceptsChronic mesenteric ischemiaCost of hospitalizationNational Inpatient SampleMesenteric ischemiaHospital factorsENDO groupCharlson Comorbidity Index scoreEnd pointComorbidity Index scorePrimary end pointSecondary end pointsTreatment of patientsHealth care costsLower mortality rateHospital mortalityHospital stayImproved mortalityLonger LOSMean LOSImproved survivalMean ageEndovascular interventionInpatient SampleOpen groupDevastating diagnosisIncreased mortality in octogenarians treated for lifestyle limiting claudication
Erben Y, Mena‐Hurtado C, Miller S, Jean R, Sumpio BJ, Velasquez CA, Mojibian H, Aruny J, Dardik A, Sumpio B. Increased mortality in octogenarians treated for lifestyle limiting claudication. Catheterization And Cardiovascular Interventions 2018, 91: 1331-1338. PMID: 29405592, DOI: 10.1002/ccd.27523.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAged, 80 and overComorbidityDatabases, FactualEndovascular ProceduresFemaleHealth StatusHumansIntermittent ClaudicationLength of StayMaleMiddle AgedPeripheral Arterial DiseaseRetrospective StudiesRisk FactorsTime FactorsTreatment OutcomeUnited StatesVascular Surgical ProceduresConceptsCharlson Comorbidity IndexOpen surgeryTreatment modalitiesHigher Charlson comorbidity indexMean Charlson Comorbidity IndexYounger cohortsInfectious wound complicationsInfra-inguinal interventionsAcute kidney injuryPeripheral arterial diseasePeripheral artery diseaseCongestive heart failureNationwide Inpatient SampleBinary logistic regression analysisLogistic regression analysisSkilled nursing facilitiesTreatment of LLCHospital mortalityComorbidity indexExercise therapyHospital stayKidney injuryOverall morbidityWound complicationsLonger LOS
2017
Distal embolization during lower extremity endovascular interventions
Chaar C, Shebl F, Sumpio B, Dardik A, Indes J, Sarac T. Distal embolization during lower extremity endovascular interventions. Journal Of Vascular Surgery 2017, 66: 143-150. PMID: 28366300, DOI: 10.1016/j.jvs.2017.01.032.Peer-Reviewed Original ResearchMeSH KeywordsAgedAmputation, SurgicalAngioplasty, BalloonAtherectomyChi-Square DistributionCritical IllnessDatabases, FactualDisease-Free SurvivalEmbolismFemaleFemoral ArteryHumansIncidenceIntermittent ClaudicationIschemiaLimb SalvageLower ExtremityMaleMiddle AgedMultivariate AnalysisNew EnglandOdds RatioPeripheral Arterial DiseaseProportional Hazards ModelsRegistriesRetrospective StudiesRisk AssessmentRisk FactorsStentsTime FactorsTreatment OutcomeVascular PatencyConceptsLower extremity endovascular interventionsSuperficial femoral arteryCritical limb ischemiaDistal embolizationLoss of patencyEndovascular interventionBalloon angioplastyLimb ischemiaAdditional endovascular interventionArterial endovascular interventionUse of atherectomyVascular Study GroupLength of occlusionNew England databaseNumber of arteriesMajor amputationMost patientsPatient characteristicsFemoral arteryRisk factorsStudy groupMultivariable regressionLimb lossLower riskAngioplasty
2016
Percutaneous endovascular aneurysm repair in morbidly obese patients
Chin JA, Skrip L, Sumpio BE, Cardella JA, Indes JE, Sarac TP, Dardik A, Chaar C. Percutaneous endovascular aneurysm repair in morbidly obese patients. Journal Of Vascular Surgery 2016, 65: 643-650.e1. PMID: 28034584, DOI: 10.1016/j.jvs.2016.06.115.Peer-Reviewed Original ResearchMeSH KeywordsAdultAneurysmCatheterization, PeripheralChi-Square DistributionDatabases, FactualEndovascular ProceduresFemaleFemoral ArteryHumansMaleMiddle AgedObesity, MorbidOperative TimePostoperative ComplicationsPuncturesRetrospective StudiesRisk FactorsTime FactorsTreatment OutcomeUnited StatesWound HealingConceptsEndovascular aneurysm repairMO patientsSuperobese patientsObese patientsAneurysm repairSurgical outcomesSevere chronic obstructive pulmonary diseaseShorter total operation timeTotal endovascular aneurysm repairChronic obstructive pulmonary diseasePercutaneous endovascular aneurysm repairSurgeons National Surgical Quality Improvement Program filesMorbidly obese patientsObstructive pulmonary diseaseSimilar baseline characteristicsPercutaneous femoral accessCurrent Procedural TerminologyPEVAR groupBaseline comorbiditiesWound complicationsBaseline characteristicsFemoral accessPulmonary diseaseTotal operation timeFemoral cutdown
2015
Cost-effectiveness of endovascular repair, open repair, and conservative management of splenic artery aneurysms
Hogendoorn W, Lavida A, Hunink MG, Moll FL, Geroulakos G, Muhs BE, Sumpio BE. Cost-effectiveness of endovascular repair, open repair, and conservative management of splenic artery aneurysms. Journal Of Vascular Surgery 2015, 61: 1432-1440. PMID: 25827968, DOI: 10.1016/j.jvs.2014.12.064.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAged, 80 and overAneurysmBlood Vessel Prosthesis ImplantationCost-Benefit AnalysisDecision Support TechniquesDecision TreesEndovascular ProceduresFemaleHealth Care CostsHumansMaleMarkov ChainsMiddle AgedModels, EconomicPatient SelectionPostoperative ComplicationsQuality of LifeRisk AssessmentRisk FactorsSex FactorsSoftwareSplenic ArteryTime FactorsTreatment OutcomeConceptsQuality-adjusted life yearsIncremental cost-effectiveness ratioHigher quality-adjusted life yearsReference case analysisProbabilistic sensitivity analysesCost-effectiveness ratioHealth care perspectiveExtensive sensitivity analysisSensitivity analysisDecision analysis modelLife yearsCost-effective treatmentSplenic artery aneurysmHypothetical cohortPerfect healthEndovascular repairConservative managementSmall gainsCostCare perspectiveFemale patientsAnalysis modelElderly patientsOpen repairArtery aneurysmVenous Ulcer: Late Complication of a Traumatic Arteriovenous Fistula
Young CJ, Dardik A, Sumpio B, Indes J, Muhs B, Chaar C. Venous Ulcer: Late Complication of a Traumatic Arteriovenous Fistula. Annals Of Vascular Surgery 2015, 29: 836.e1-836.e3. PMID: 25725283, DOI: 10.1016/j.avsg.2014.11.020.Peer-Reviewed Case Reports and Technical NotesConceptsTraumatic AVFsLate complicationsArteriovenous fistula formationCongestive heart failureTraumatic arteriovenous fistulaDistal ischemiaHard signsVenous dilatationHeart failureInitial presentationOpen repairFistula formationVenous congestionArteriovenous fistulaVascular injuryCase reportAVFOperating roomComplicationsInjurySignsFistulaIschemiaUlcersPatients
2014
Open repair, endovascular repair, and conservative management of true splenic artery aneurysms
Hogendoorn W, Lavida A, Hunink MG, Moll FL, Geroulakos G, Muhs BE, Sumpio BE. Open repair, endovascular repair, and conservative management of true splenic artery aneurysms. Journal Of Vascular Surgery 2014, 60: 1667-1676.e1. PMID: 25264364, DOI: 10.1016/j.jvs.2014.08.067.Peer-Reviewed Original ResearchConceptsTrue splenic artery aneurysmsSplenic artery aneurysmLate mortality rateEndovascular repairConservative managementSystematic reviewPerioperative mortalityOpen repairArtery aneurysmMortality rateManagement of SAAHigher late mortality rateRuptured splenic artery aneurysmEV groupGood short-term resultsHigh perioperative mortalityLow perioperative mortalityNumber of reinterventionsMajor treatment modalityTreatment of choiceSmall-sized aneurysmsMeta-Analyses (PRISMA) guidelinesShort-term resultsPreferred Reporting ItemsCONS groupCosts of repair of abdominal aortic aneurysm with different devices in a multicenter randomized trial
Matsumura JS, Stroupe KT, Lederle FA, Kyriakides TC, Ge L, Freischlag JA, Ketteler E, Kingsley D, Marek J, Massen R, Matteson B, Pitcher J, Langsfeld M, Corson J, Goff J, Kasirajan K, Paap C, Robertson D, Salam A, Veeraswamy R, Milner R, Kasirajan K, Guidot J, Lal B, Busuttil S, Lilly M, Braganza M, Ellis K, Patterson M, Jordan W, Whitley D, Taylor S, Passman M, Kerns D, Inman C, Poirier J, Ebaugh J, Raffetto J, Chew D, Lathi S, Owens C, Hickson K, Dosluoglu H, Eschberger K, Kibbe M, Baraniewski H, Matsumura J, Endo M, Busman A, Meadows W, Evans M, Giglia J, Sayed H, Reed A, Ruf M, Ross S, Jean-Claude J, Pinault G, Kang P, White N, Eiseman M, Jones R, Timaran C, Modrall J, Welborn M, Lopez J, Nguyen T, Chacko J, Granke K, Vouyouka A, Olgren E, Chand P, Allende B, Ranella M, Yales C, Whitehill T, Krupski W, Nehler M, Johnson S, Jones D, Strecker P, Bhola M, Shortell C, Gray J, Lawson J, McCann R, Sebastian M, Tetterton J, Blackwell C, Prinzo P, Lee N, Padberg F, Cerveira J, Lal B, Zickler R, Hauck K, Berceli S, Lee W, Ozaki C, Nelson P, Irwin A, Baum R, Aulivola B, Rodriguez H, Littooy F, Greisler H, O'Sullivan M, Kougias P, Lin P, Bush R, Guinn G, Cagiannos C, Pillack S, Guillory B, Cikrit D, Lalka S, Lemmon G, Nachreiner R, Rusomaroff M, O'Brien E, Cullen J, Hoballah J, Sharp W, McCandless J, Beach V, Minion D, Schwarcz T, Kimbrough J, Ashe L, Rockich A, Warner-Carpenter J, Moursi M, Eidt J, Brock S, Bianchi C, Bishop V, Gordon I, Fujitani R, Kubaska S, Behdad M, Azadegan R, Agas C, Zalecki K, Hoch J, Carr S, Acher C, Schwarze M, Tefera G, Mell M, Dunlap B, Rieder J, Stuart J, Weiman D, Abul-Khoudoud O, Garrett H, Walsh S, Wilson K, Seabrook G, Cambria R, Brown K, Lewis B, Framberg S, Kallio C, Barke R, Santilli S, d'Audiffret A, Oberle N, Proebstle C, Johnson L, Jacobowitz G, Cayne N, Rockman C, Adelman M, Gagne P, Nalbandian M, Caropolo L, Pipinos I, Johanning J, Lynch T, DeSpiegelaere H, Purviance G, Zhou W, Dalman R, Lee J, Safadi B, Coogan S, Wren S, Bahmani D, Maples D, Thunen S, Golden M, Mitchell M, Fairman R, Reinhardt S, Wilson M, Tzeng E, Muluk S, Peterson N, Foster M, Edwards J, Moneta G, Landry G, Taylor L, Yeager R, Cannady E, Treiman G, Hatton-Ward S, Salabsky B, Kansal N, Owens E, Estes M, Forbes B, Sobotta C, Rapp J, Reilly L, Perez S, Yan K, Sarkar R, Dwyer S, Kohler T, Hatsukami T, Glickerman D, Sobel M, Burdick T, Pedersen K, Cleary P, Kansal N, Owens E, Estes M, Forbes B, Sobotta C, Back M, Bandyk D, Johnson B, Shames M, Reinhard R, Thomas S, Hunter G, Leon L, Westerband A, Guerra R, Riveros M, Mills J, Hughes J, Escalante A, Psalms S, Day N, Macsata R, Sidawy A, Weiswasser J, Arora S, Jasper B, Dardik A, Gahtan V, Muhs B, Sumpio B, Gusberg R, Spector M, Pollak J, Aruny J, Kelly E, Wong J, Vasilas P, Joncas C, Gelabert H, DeVirgillio C, Rigberg D, Cole L. Costs of repair of abdominal aortic aneurysm with different devices in a multicenter randomized trial. Journal Of Vascular Surgery 2014, 61: 59-65.e2. PMID: 25238728, DOI: 10.1016/j.jvs.2014.08.003.Peer-Reviewed Original ResearchMeSH KeywordsAortic Aneurysm, AbdominalBlood Vessel ProsthesisBlood Vessel Prosthesis ImplantationEndovascular ProceduresHealth Care CostsHealth ExpendituresHospital CostsHumansLength of StayProsthesis DesignStentsTime FactorsTreatment OutcomeUnited StatesUnited States Department of Veterans AffairsConceptsTotal health care costsHealth care costsEndovascular repairAbdominal aortic aneurysmHealth care providersCare costsAneurysm repairAortic aneurysmVA costsAbdominal aortic aneurysm repairPatient's health care providersVeterans Affairs Cooperative StudyImplant costsHealth care utilization dataVA Health Economics Resource CenterOpen repair cohortsOpen repair groupAortic aneurysm repairEndovascular aneurysm repairInitial hospitalization costsHealth care system expendituresLower mean costQuality of lifeMean deviceMethod of repairEndovascular vs. Open Repair of Complicated Acute Type B Aortic Dissections
Hogendoorn W, Hunink MG, Schlösser FJ, Moll FL, Sumpio BE, Muhs BE. Endovascular vs. Open Repair of Complicated Acute Type B Aortic Dissections. Journal Of Endovascular Therapy 2014, 21: 503-514. PMID: 25101577, DOI: 10.1583/14-4716r.1.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAortic Aneurysm, ThoracicAortic DissectionComparative Effectiveness ResearchComputer SimulationDecision Support TechniquesEndovascular ProceduresEvidence-Based MedicineHumansMaleMarkov ChainsMiddle AgedPatient SelectionPostoperative ComplicationsQuality-Adjusted Life YearsReoperationRisk FactorsTime FactorsTreatment OutcomeVascular Surgical ProceduresConceptsComplicated acute type B aortic dissectionThoracic endovascular aortic repairOpen surgical repairQuality-adjusted life yearsAcute type B aortic dissectionType B aortic dissectionB aortic dissectionAortic dissectionAge groupsNumber of reinterventionsEndovascular aortic repairAortic-related complicationsDifferent clinical scenariosProbabilistic sensitivity analysesPerioperative mortalityEndovascular repairAortic repairOpen repairSurgical repairRelative riskMAIN OUTCOMEAortic anatomyClinical scenariosLife yearsComparative effectivenessA comparison of open and endovascular revascularization for chronic mesenteric ischemia in a clinical decision model
Hogendoorn W, Hunink MG, Schlösser FJ, Moll FL, Muhs BE, Sumpio BE. A comparison of open and endovascular revascularization for chronic mesenteric ischemia in a clinical decision model. Journal Of Vascular Surgery 2014, 60: 715-725.e2. PMID: 24721175, DOI: 10.1016/j.jvs.2014.03.009.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAged, 80 and overComparative Effectiveness ResearchComputer SimulationCost-Benefit AnalysisDecision Support TechniquesEndovascular ProceduresFemaleHealth Care CostsHumansIschemiaMaleMarkov ChainsMesenteric IschemiaMiddle AgedPatient SelectionPredictive Value of TestsQuality of LifeQuality-Adjusted Life YearsReoperationRisk AssessmentRisk FactorsSex FactorsTime FactorsTreatment OutcomeVascular DiseasesVascular PatencyVascular Surgical ProceduresConceptsChronic mesenteric ischemiaIncremental cost-effectiveness ratioEndovascular revascularizationCost-effectiveness ratioMesenteric ischemiaFemale patientsMortality riskAge groupsGood short-term resultsDisease-specific mortality riskPatients 60 yearsOverall mortality riskMarkov state transition modelTreatment of choiceExpensive treatment strategiesShort-term resultsHealth care perspectiveHealth care costsDifferent clinical scenariosProbabilistic sensitivity analysesClinical decision modelDecision analysis modelOlder patientsConservative managementYounger patients
2013
PECAM-1 phosphorylation and tissue factor expression in HUVECs exposed to uniform and disturbed pulsatile flow and chemical stimuli
Moriguchi T, Sumpio BE. PECAM-1 phosphorylation and tissue factor expression in HUVECs exposed to uniform and disturbed pulsatile flow and chemical stimuli. Journal Of Vascular Surgery 2013, 61: 481-488. PMID: 24342062, DOI: 10.1016/j.jvs.2013.09.059.Peer-Reviewed Original ResearchThoracic endovascular aortic repair with the chimney graft technique
Hogendoorn W, Schlösser FJ, Moll FL, Sumpio BE, Muhs BE. Thoracic endovascular aortic repair with the chimney graft technique. Journal Of Vascular Surgery 2013, 58: 502-511. PMID: 23697513, DOI: 10.1016/j.jvs.2013.03.043.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAorta, ThoracicAortic DiseasesBlood Vessel ProsthesisBlood Vessel Prosthesis ImplantationChildElective Surgical ProceduresEmergenciesEndoleakEndovascular ProceduresFemaleHumansMaleMiddle AgedRisk FactorsStentsStrokeTime FactorsTreatment OutcomeVascular PatencyYoung AdultConceptsThoracic endovascular aortic repairChimney graft techniqueEndovascular aortic repairElective settingChimney stentsChimney techniqueAortic repairTreatment strategiesGraft techniqueLeft common carotid arteryAortic arch branchesOverall perioperative mortalityAortic side branchesLeft subclavian arteryThoracic aortic pathologyViable treatment optionCommon carotid arterySelf-expandable stentsBalloon-expandable stentsPerioperative mortalityAortic pathologySubclavian arteryArch branchesBrachiocephalic arteryEmergent setting
2012
Lower extremity limb salvage with cryoplasty: a single-center cohort study
Basco MT, Schlösser FJ, Muhs BE, Indes JE, Blume PA, Key JJ, Aruny JE, Sumpio BE. Lower extremity limb salvage with cryoplasty: a single-center cohort study. Vascular 2012, 20: 36-41. PMID: 22328618, DOI: 10.1258/vasc.2011.oa0309.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAmputation, SurgicalChi-Square DistributionConnecticutCryosurgeryFemaleHumansIschemiaKaplan-Meier EstimateLimb SalvageLower ExtremityMaleMiddle AgedPatient SelectionPeripheral Arterial DiseaseRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeConceptsChronic critical limb ischemiaCritical limb ischemiaCohort studyLimb ischemiaArtery diseaseSalvage rateSingle-center cohort studyRetrospective cohort studyLimb salvage ratePeripheral artery diseaseHistory of smokingLower extremity revascularizationCoronary artery diseaseKaplan-Meier analysisTechnical success rateLower extremity limb salvagePoor wound healingLower extremity lesionsRecent clinical experienceInadequate conduitMajor amputationPersistent ulcerationRest painSurgical revascularizationUncontrolled hypertension
2011
Laminar shear, but not orbital shear, has a synergistic effect with thrombin stimulation on tissue factor expression in human umbilical vein endothelial cells
Rochier A, Nixon A, Yamashita N, Abe R, Abe R, Madri JA, Sumpio BE. Laminar shear, but not orbital shear, has a synergistic effect with thrombin stimulation on tissue factor expression in human umbilical vein endothelial cells. Journal Of Vascular Surgery 2011, 54: 480-488. PMID: 21367569, DOI: 10.1016/j.jvs.2011.01.002.Peer-Reviewed Original ResearchAnalysis of VarianceBlotting, WesternCell Culture TechniquesCells, CulturedEndothelial CellsEnzyme ActivationHumansMechanotransduction, CellularMitogen-Activated Protein Kinase 1Mitogen-Activated Protein Kinase 3P38 Mitogen-Activated Protein KinasesPhosphorylationProtein Kinase InhibitorsRNA, MessengerStress, MechanicalThrombinThromboplastinTime FactorsUp-RegulationOlive Oil Polyphenol Oleuropein Inhibits Smooth Muscle Cell Proliferation
Abe R, Beckett J, Abe R, Nixon A, Rochier A, Yamashita N, Sumpio B. Olive Oil Polyphenol Oleuropein Inhibits Smooth Muscle Cell Proliferation. European Journal Of Vascular And Endovascular Surgery 2011, 41: 814-820. PMID: 21333557, DOI: 10.1016/j.ejvs.2010.12.021.Peer-Reviewed Original ResearchConceptsSmooth muscle cell proliferationMuscle cell proliferationCell cycle analysisSMC proliferationCell proliferationInhibits Smooth Muscle Cell ProliferationVascular smooth muscle cell proliferationCoronary artery diseaseNon-treated groupExtracellular signal-regulated kinase 1/2 activationCardiovascular mortalityArtery diseaseKinase 1/2 activationCell cycle blockG1-S phaseMediterranean dietDay 1Oleuropein treatmentGrowth of SMCsG1 phase regulatorsFlow cytometryVascular SMCsPresence of oleuropeinBeneficial effectsCycle analysis