Negative Regulation of Monocyte Adhesion to Arterial Elastic Laminae by Signal Regulatory Protein α and Src Homology 2 Domain-containing Protein-Tyrosine Phosphatase-1*
Liu SQ, Alkema PK, Tieché C, Tefft BJ, Liu DZ, Li YC, Sumpio BE, Caprini JA, Paniagua M. Negative Regulation of Monocyte Adhesion to Arterial Elastic Laminae by Signal Regulatory Protein α and Src Homology 2 Domain-containing Protein-Tyrosine Phosphatase-1*. Journal Of Biological Chemistry 2005, 280: 39294-39301. PMID: 16159885, DOI: 10.1074/jbc.m503866200.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsArteriesCell AdhesionElastic TissueIn Vitro TechniquesIntracellular Signaling Peptides and ProteinsLeukocytesMonocytesPhosphorylationProtein Phosphatase 1Protein Tyrosine Phosphatase, Non-Receptor Type 6Protein Tyrosine PhosphatasesRatsRats, Sprague-DawleyReceptors, Cell SurfaceRNA, Small InterferingConceptsSHP-1Arterial elastic laminaeSrc homology 2 domain-containing protein tyrosine phosphataseSIRP-alphaSrc homology 2 domain-containing protein tyrosine phosphatase 1Protein tyrosine phosphatase 1Protein tyrosine phosphataseSignal regulatory protein alphaSignal regulatory protein αRegulatory protein alphaExtracellular matrix constituentsMonocyte adhesionArterial morphogenesisPhosphatase 1Regulatory protein αNegative regulationProtein alphaProtein αImportant functionsInduced activationDegradation peptidesInhibitory effectElasticity of arteriesAdhesionMatrix constituents